| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Lidocaine (hydrochloride) perturbation in SW 900 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Lidocaine (hydrochloride)_SW 900 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EXT1 | exostosin glycosyltransferase 1 | 0.161085 |
| HMGA2 | high mobility group AT-hook 2 | 0.157781 |
| FN1 | fibronectin 1 | 0.130361 |
| TMEM156 | transmembrane protein 156 | 0.123552 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | 0.0938945 |
| NTN4 | netrin 4 | 0.088195 |
| NRP1 | neuropilin 1 | 0.0850261 |
| ASPH | aspartate beta-hydroxylase | 0.0834579 |
| GLIS3 | GLIS family zinc finger 3 | 0.0803606 |
| VCL | vinculin | 0.0792966 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0782925 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0772879 |
| OSMR | oncostatin M receptor | 0.0764463 |
| ITGA1 | integrin, alpha 1 | 0.0755573 |
| SEPTIN9 | septin 9 | 0.0746212 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0717751 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0705661 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0685493 |
| SMAD3 | SMAD family member 3 | 0.0678106 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.0657872 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | 0.0635446 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0634973 |
| RNF213 | ring finger protein 213 | 0.0630433 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0629801 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | 0.0608152 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0601336 |
| DST | dystonin | 0.0573567 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0561844 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.055606 |
| ETV1 | ets variant 1 | 0.0551241 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0542963 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 0.0538385 |
| KSR1 | kinase suppressor of ras 1 | 0.0537954 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | 0.0534437 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0514604 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0514241 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.0513946 |
| SYT1 | synaptotagmin I | 0.0501156 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | 0.0501007 |
| RAB10 | RAB10, member RAS oncogene family | 0.0476134 |
| NXN | nucleoredoxin | 0.0467139 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0458363 |
| TPI1 | triosephosphate isomerase 1 | 0.0457409 |
| SVIL | supervillin | 0.0454726 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0449125 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0446208 |
| KLHL5 | kelch-like family member 5 | 0.0443139 |
| ACTG1 | actin gamma 1 | 0.044177 |
| SFTPA2 | surfactant protein A2 | 0.0438482 |
| CENPF | centromere protein F, 350/400kDa | 0.0435918 |
| FOXP1 | forkhead box P1 | 0.0425841 |
| BPTF | bromodomain PHD finger transcription factor | 0.041989 |
| FTL | ferritin, light polypeptide | 0.041922 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0418355 |
| FLNA | filamin A, alpha | 0.0418317 |
| MLPH | melanophilin | 0.0416719 |
| RASAL2 | RAS protein activator like 2 | 0.0403933 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0394659 |
| RBMS1 | RNA binding motif, single stranded interacting protein 1 | 0.0392873 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0390297 |
| FHL2 | four and a half LIM domains 2 | 0.0389215 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0389006 |
| PALLD | palladin, cytoskeletal associated protein | 0.0387977 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0387496 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0381828 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0380287 |
| CD44 | CD44 molecule (Indian blood group) | 0.0378657 |
| RAB31 | RAB31, member RAS oncogene family | 0.0376679 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0374926 |
| ECE1 | endothelin converting enzyme 1 | 0.0372089 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0369527 |
| LMNA | lamin A/C | 0.0366002 |
| TGFB2 | transforming growth factor, beta 2 | 0.0364933 |
| MYO10 | myosin X | 0.0364048 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0363485 |
| ENAH | enabled homolog (Drosophila) | 0.0355753 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0352547 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0352427 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0350747 |
| MX2 | MX dynamin-like GTPase 2 | 0.0346696 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0343595 |
| DUSP16 | dual specificity phosphatase 16 | 0.0342413 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0338162 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | 0.0338103 |
| PELO | pelota homolog (Drosophila) | 0.0336943 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0335417 |
| ADAR | adenosine deaminase, RNA-specific | 0.0329304 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.0329232 |
| ATXN1 | ataxin 1 | 0.0326857 |
| ERBIN | erbb2 interacting protein | 0.032666 |
| CAPN2 | calpain 2, (m/II) large subunit | 0.0325378 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0324861 |
| LY6E | lymphocyte antigen 6 complex, locus E | 0.0324563 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0323712 |
| ABR | active BCR-related | 0.0323619 |
| RUNX2 | runt-related transcription factor 2 | 0.0323581 |
| SSH1 | slingshot protein phosphatase 1 | 0.0320759 |
| SDC2 | syndecan 2 | 0.0319461 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0318963 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | 0.0316442 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.230836 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.180455 |
| CANX | calnexin | -0.121235 |
| NDRG1 | N-myc downstream regulated 1 | -0.074259 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0741164 |
| UBC | ubiquitin C | -0.0701826 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0664015 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0660681 |
| PTMA | prothymosin, alpha | -0.0588346 |
| RPS27A | ribosomal protein S27a | -0.0576758 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0545207 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0468249 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0466932 |
| TMSB10 | thymosin beta 10 | -0.0449529 |
| CALR | calreticulin | -0.0409442 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0394448 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0383077 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0369494 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0363791 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0347722 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0315775 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0312553 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0308491 |
| ZNF292 | zinc finger protein 292 | -0.0298851 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0287687 |
| ERO1B | endoplasmic reticulum oxidoreductase 1 beta | -0.0283731 |
| LRRC23 | leucine rich repeat containing 23 | -0.0278785 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0278146 |
| CALU | calumenin | -0.0270654 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0266011 |
| IFRD1 | interferon-related developmental regulator 1 | -0.026088 |
| TMEM263 | transmembrane protein 263 | -0.0257979 |
| EIF2AK3 | eukaryotic translation initiation factor 2-alpha kinase 3 | -0.0243277 |
| CADM1 | cell adhesion molecule 1 | -0.0242916 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0242434 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0239569 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0239314 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0234474 |
| PAG1 | phosphoprotein membrane anchor with glycosphingolipid microdomains 1 | -0.023267 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | -0.0223018 |
| ARF4 | ADP-ribosylation factor 4 | -0.0222919 |
| MMP13 | matrix metallopeptidase 13 | -0.0217524 |
| OGA | O-GlcNAcase | -0.0213799 |
| FRY | furry homolog (Drosophila) | -0.0213408 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0211499 |
| MT2A | metallothionein 2A | -0.0207542 |
| CAPZA2 | capping protein (actin filament) muscle Z-line, alpha 2 | -0.0206363 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0201217 |
| SUCO | SUN domain containing ossification factor | -0.0198386 |
| COG6 | component of oligomeric golgi complex 6 | -0.0197938 |
| RPL23 | ribosomal protein L23 | -0.0193961 |
| TUFT1 | tuftelin 1 | -0.0192587 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0192354 |
| POU2F2 | POU class 2 homeobox 2 | -0.0191628 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0191197 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0190657 |
| RNMT | RNA (guanine-7-) methyltransferase | -0.018718 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0186666 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | -0.0184323 |
| SEPTIN2 | septin 2 | -0.0182908 |
| RSF1 | remodeling and spacing factor 1 | -0.0182294 |
| FGF18 | fibroblast growth factor 18 | -0.0181532 |
| CCDC138 | coiled-coil domain containing 138 | -0.0174255 |
| TMF1 | TATA element modulatory factor 1 | -0.0171943 |
| SRP54 | signal recognition particle 54kDa | -0.0171314 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.017131 |
| BTBD9 | BTB (POZ) domain containing 9 | -0.0169149 |
| GPR75-ASB3 | GPR75-ASB3 readthrough | -0.016782 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | -0.0163702 |
| SNX14 | sorting nexin 14 | -0.0163323 |
| CRELD2 | cysteine-rich with EGF-like domains 2 | -0.0162846 |
| ELOVL5 | ELOVL fatty acid elongase 5 | -0.0162122 |
| LAMB3 | laminin, beta 3 | -0.0161668 |
| TOR1AIP2 | torsin A interacting protein 2 | -0.0159039 |
| SPAG9 | sperm associated antigen 9 | -0.015807 |
| FAM13A | family with sequence similarity 13, member A | -0.015714 |
| MORF4L2 | mortality factor 4 like 2 | -0.0156102 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0155448 |
| HBP1 | HMG-box transcription factor 1 | -0.0154495 |
| PIM3 | Pim-3 proto-oncogene, serine/threonine kinase | -0.0153573 |
| INTS6 | integrator complex subunit 6 | -0.0151592 |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) | -0.0151024 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | -0.0150052 |
| TFG | TRK-fused gene | -0.0149891 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0149877 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -0.0149561 |
| SMAP1 | small ArfGAP 1 | -0.0149396 |
| NDEL1 | nudE neurodevelopment protein 1-like 1 | -0.0149297 |
| FOSL1 | FOS-like antigen 1 | -0.0149295 |
| ZNF841 | zinc finger protein 841 | -0.0147884 |
| TTC23L | tetratricopeptide repeat domain 23-like | -0.0145996 |
| PPP1CB | protein phosphatase 1, catalytic subunit, beta isozyme | -0.0141299 |
| TENT4A | terminal nucleotidyltransferase 4A | -0.0140294 |
| CAMTA1 | calmodulin binding transcription activator 1 | -0.0140143 |
| CSGALNACT2 | chondroitin sulfate N-acetylgalactosaminyltransferase 2 | -0.0139131 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.013907 |
| RANBP2 | RAN binding protein 2 | -0.0138843 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0138486 |
| RHEB | Ras homolog enriched in brain | -0.0137915 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | -0.013741 |
