| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Lidocaine (hydrochloride) perturbation in SW1417 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Lidocaine (hydrochloride)_SW1417 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.109216 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0938954 |
| KRT8 | keratin 8, type II | 0.0855323 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0772077 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0748792 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.0735886 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0715787 |
| H1-0 | H1.0 linker histone | 0.0691484 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0633013 |
| MYOF | myoferlin | 0.0628498 |
| ANXA2 | annexin A2 | 0.0626822 |
| SERINC5 | serine incorporator 5 | 0.0604626 |
| KRT18 | keratin 18, type I | 0.060072 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.0600289 |
| MYO1E | myosin IE | 0.0589677 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0570274 |
| ACTN4 | actinin, alpha 4 | 0.0542473 |
| CCND1 | cyclin D1 | 0.0536504 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | 0.0521264 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | 0.0518411 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0510152 |
| PERP | PERP, TP53 apoptosis effector | 0.0509811 |
| KRT20 | keratin 20, type I | 0.0509708 |
| LDHA | lactate dehydrogenase A | 0.0500649 |
| ADAM19 | ADAM metallopeptidase domain 19 | 0.0498035 |
| ACTG1 | actin gamma 1 | 0.0491499 |
| SMAD3 | SMAD family member 3 | 0.0484273 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0483724 |
| NEBL | nebulette | 0.0474951 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0474518 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0468351 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0463579 |
| FLNA | filamin A, alpha | 0.0461069 |
| FAT1 | FAT atypical cadherin 1 | 0.0456866 |
| YAP1 | Yes-associated protein 1 | 0.0451142 |
| RPLP0 | ribosomal protein, large, P0 | 0.0443408 |
| OSBPL10 | oxysterol binding protein-like 10 | 0.043502 |
| TMEM123 | transmembrane protein 123 | 0.0432522 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0427425 |
| VCL | vinculin | 0.0422814 |
| MACC1 | metastasis associated in colon cancer 1 | 0.0420903 |
| EPCAM | epithelial cell adhesion molecule | 0.0420725 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0420061 |
| MKI67 | marker of proliferation Ki-67 | 0.0405551 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0402371 |
| UBC | ubiquitin C | 0.0397048 |
| CTDSPL | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like | 0.0397005 |
| ETV6 | ets variant 6 | 0.0391262 |
| EZR | ezrin | 0.0380342 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0375382 |
| STT3B | STT3B, subunit of the oligosaccharyltransferase complex (catalytic) | 0.0373435 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0373001 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 | 0.0371211 |
| FHL2 | four and a half LIM domains 2 | 0.0367704 |
| EHF | ets homologous factor | 0.0366105 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.036067 |
| TRIM2 | tripartite motif containing 2 | 0.0356798 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0356047 |
| WWOX | WW domain containing oxidoreductase | 0.0352546 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0352506 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | 0.0352143 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | 0.0346668 |
| EGFR | epidermal growth factor receptor | 0.0341442 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0336805 |
| CD9 | CD9 molecule | 0.0334384 |
| TMSB4X | thymosin beta 4, X-linked | 0.0332032 |
| ZNRF3 | zinc and ring finger 3 | 0.0331407 |
| SMAD2 | SMAD family member 2 | 0.0328891 |
| PLSCR1 | phospholipid scramblase 1 | 0.03256 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0324807 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 0.0311527 |
| DSPP | dentin sialophosphoprotein | 0.0310763 |
| CSE1L | CSE1 chromosome segregation 1-like (yeast) | 0.0310742 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0310622 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0307579 |
| SQSTM1 | sequestosome 1 | 0.0307474 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | 0.0305517 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0304907 |
| FHIT | fragile histidine triad | 0.0304714 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | 0.030405 |
| MYO10 | myosin X | 0.030332 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.0294679 |
| KPNB1 | karyopherin (importin) beta 1 | 0.0292602 |
| RNF213 | ring finger protein 213 | 0.0291575 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0290733 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0289312 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0288787 |
| PARD3B | par-3 family cell polarity regulator beta | 0.0288749 |
| TOM1L2 | target of myb1-like 2 (chicken) | 0.0288257 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.028795 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0287156 |
| SKAP2 | src kinase associated phosphoprotein 2 | 0.0285011 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0283541 |
| OXR1 | oxidation resistance 1 | 0.0281935 |
| FAM3C | family with sequence similarity 3, member C | 0.0281041 |
| RPL12 | ribosomal protein L12 | 0.0280199 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0273785 |
| PATJ | PATJ crumbs cell polarity complex component | 0.0271088 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0270558 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0270077 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | -0.086313 |
| NDRG1 | N-myc downstream regulated 1 | -0.0576721 |
| FNDC3B | fibronectin type III domain containing 3B | -0.048312 |
| RPS6 | ribosomal protein S6 | -0.0448043 |
| TMSB10 | thymosin beta 10 | -0.0388481 |
| RPLP2 | ribosomal protein, large, P2 | -0.0386996 |
| GOLGA4 | golgin A4 | -0.0342192 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | -0.0338707 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0334369 |
| RPS21 | ribosomal protein S21 | -0.0319718 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0314869 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0314597 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0305337 |
| TMF1 | TATA element modulatory factor 1 | -0.029803 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0295304 |
| JMJD1C | jumonji domain containing 1C | -0.0278141 |
| GOLGB1 | golgin B1 | -0.0273531 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0266684 |
| CCNL1 | cyclin L1 | -0.0262914 |
| CDK13 | cyclin-dependent kinase 13 | -0.0262729 |
| NFIA | nuclear factor I/A | -0.0245626 |
| RPS19 | ribosomal protein S19 | -0.0242388 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0236968 |
| BBX | bobby sox homolog (Drosophila) | -0.0236812 |
| RBM39 | RNA binding motif protein 39 | -0.0233817 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0224793 |
| TMEM39A | transmembrane protein 39A | -0.0224249 |
| ARF4 | ADP-ribosylation factor 4 | -0.0220563 |
| EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit | -0.0216997 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0216493 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0213884 |
| RPS13 | ribosomal protein S13 | -0.0211247 |
| VEGFA | vascular endothelial growth factor A | -0.0210702 |
| ATP1A4 | ATPase, Na+/K+ transporting, alpha 4 polypeptide | -0.0207042 |
| STC2 | stanniocalcin 2 | -0.0204417 |
| RPS17 | ribosomal protein S17 | -0.0200303 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0198698 |
| NCOR2 | nuclear receptor corepressor 2 | -0.0197398 |
| TXNDC11 | thioredoxin domain containing 11 | -0.0197334 |
| FBXO11 | F-box protein 11 | -0.019501 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | -0.0194351 |
| HM13 | histocompatibility (minor) 13 | -0.0188536 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.018706 |
| RRBP1 | ribosome binding protein 1 | -0.0186842 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0186298 |
| LENG8 | leukocyte receptor cluster (LRC) member 8 | -0.0183105 |
| RAB6A | RAB6A, member RAS oncogene family | -0.0181585 |
| PDIA5 | protein disulfide isomerase family A, member 5 | -0.0180682 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 | -0.0177891 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0177408 |
| COPA | coatomer protein complex, subunit alpha | -0.0176986 |
| RPL35A | ribosomal protein L35a | -0.017382 |
| KDM6A | lysine (K)-specific demethylase 6A | -0.0173415 |
| SCAF4 | SR-related CTD-associated factor 4 | -0.0172514 |
| EWSR1 | EWS RNA-binding protein 1 | -0.0172359 |
| SEC61A1 | Sec61 alpha 1 subunit (S. cerevisiae) | -0.017128 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0169788 |
| PTK2 | protein tyrosine kinase 2 | -0.0167058 |
| RPS3 | ribosomal protein S3 | -0.0164424 |
| VMP1 | vacuole membrane protein 1 | -0.0162387 |
| FAM107B | family with sequence similarity 107, member B | -0.0161253 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.0161087 |
| ZMIZ2 | zinc finger, MIZ-type containing 2 | -0.0160988 |
| CNOT4 | CCR4-NOT transcription complex, subunit 4 | -0.0158818 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0158401 |
| ZNF148 | zinc finger protein 148 | -0.0158273 |
| FOXO1 | forkhead box O1 | -0.0157565 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0157014 |
| PPP3R1 | protein phosphatase 3, regulatory subunit B, alpha | -0.0156092 |
| SRPK2 | SRSF protein kinase 2 | -0.0155554 |
| BRD4 | bromodomain containing 4 | -0.0152805 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | -0.0150885 |
| FOXO3 | forkhead box O3 | -0.0149465 |
| RBM12 | RNA binding motif protein 12 | -0.0148409 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0147716 |
| SRSF6 | serine/arginine-rich splicing factor 6 | -0.0147456 |
| USP36 | ubiquitin specific peptidase 36 | -0.0146846 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0146658 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0146397 |
| EIF2AK3 | eukaryotic translation initiation factor 2-alpha kinase 3 | -0.0145282 |
| FOSL1 | FOS-like antigen 1 | -0.0144546 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase | -0.014432 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | -0.0143202 |
| PPARG | peroxisome proliferator-activated receptor gamma | -0.0143176 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | -0.0141249 |
| RPL37A | ribosomal protein L37a | -0.0140985 |
| RPRD1B | regulation of nuclear pre-mRNA domain containing 1B | -0.0140075 |
| UNC13A | unc-13 homolog A (C. elegans) | -0.0139169 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | -0.013828 |
| RBM25 | RNA binding motif protein 25 | -0.0137641 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | -0.0137293 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0136862 |
| ANKRD11 | ankyrin repeat domain 11 | -0.01368 |
| RYK | receptor-like tyrosine kinase | -0.0135983 |
| SRP54 | signal recognition particle 54kDa | -0.0135402 |
| CREB3L2 | cAMP responsive element binding protein 3-like 2 | -0.0134899 |
| MAX | MYC associated factor X | -0.0134505 |
| NRXN1 | neurexin 1 | -0.0134454 |
| CHKA | choline kinase alpha | -0.0132928 |
| RPS29 | ribosomal protein S29 | -0.0132779 |
