| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Lidocaine (hydrochloride) perturbation in hTERT-HPNE cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Lidocaine (hydrochloride)_hTERT-HPNE drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.253822 |
| COL6A3 | collagen, type VI, alpha 3 | 0.207772 |
| FN1 | fibronectin 1 | 0.172324 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.142272 |
| INHBA | inhibin, beta A | 0.121417 |
| COL1A1 | collagen, type I, alpha 1 | 0.113575 |
| NAV1 | neuron navigator 1 | 0.10135 |
| MYO10 | myosin X | 0.0984145 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0970887 |
| COL6A2 | collagen, type VI, alpha 2 | 0.0928206 |
| CD44 | CD44 molecule (Indian blood group) | 0.0927969 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0883199 |
| GLIS3 | GLIS family zinc finger 3 | 0.0854433 |
| ACTG1 | actin gamma 1 | 0.0820037 |
| WNT5A | wingless-type MMTV integration site family, member 5A | 0.0789508 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0777659 |
| FRMD4A | FERM domain containing 4A | 0.0776934 |
| CALD1 | caldesmon 1 | 0.076696 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.075672 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0737039 |
| CD59 | CD59 molecule, complement regulatory protein | 0.0731855 |
| ASPH | aspartate beta-hydroxylase | 0.0705274 |
| ADGRB3 | adhesion G protein-coupled receptor B3 | 0.0693358 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.0682498 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0659837 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0654258 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0652601 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0641202 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0625126 |
| VCL | vinculin | 0.0620226 |
| VIM | vimentin | 0.0599088 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0585459 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0554571 |
| COL5A3 | collagen, type V, alpha 3 | 0.0549887 |
| SMAD3 | SMAD family member 3 | 0.0548059 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0546743 |
| LOX | lysyl oxidase | 0.053988 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0533149 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0532904 |
| EMP1 | epithelial membrane protein 1 | 0.0524015 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0523918 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | 0.0505817 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0499492 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | 0.0492537 |
| AHNAK | AHNAK nucleoprotein | 0.0490838 |
| DSPP | dentin sialophosphoprotein | 0.0488859 |
| CAVIN1 | caveolae associated protein 1 | 0.0483936 |
| COL1A2 | collagen, type I, alpha 2 | 0.0480224 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0478513 |
| EGFR | epidermal growth factor receptor | 0.0462864 |
| DST | dystonin | 0.044803 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0441464 |
| ANXA2 | annexin A2 | 0.0437159 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0434523 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0431054 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | 0.0428446 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0427967 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0426994 |
| FLNA | filamin A, alpha | 0.0416355 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | 0.0415369 |
| LDHA | lactate dehydrogenase A | 0.0412749 |
| CALU | calumenin | 0.040471 |
| MED13L | mediator complex subunit 13-like | 0.0395122 |
| FBN1 | fibrillin 1 | 0.0395068 |
| COL4A2 | collagen, type IV, alpha 2 | 0.0394266 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0381676 |
| SEPTIN9 | septin 9 | 0.0375676 |
| ARHGAP24 | Rho GTPase activating protein 24 | 0.0371887 |
| ANKRD28 | ankyrin repeat domain 28 | 0.037028 |
| PLEC | plectin | 0.0358358 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.0357031 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | 0.0353917 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0347183 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | 0.0344905 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0332785 |
| FAT1 | FAT atypical cadherin 1 | 0.0330179 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0329804 |
| FOXP1 | forkhead box P1 | 0.0329566 |
| CDK6 | cyclin-dependent kinase 6 | 0.0328123 |
| IGFBP7 | insulin-like growth factor binding protein 7 | 0.0326754 |
| PRSS23 | protease, serine, 23 | 0.0316034 |
| STARD13 | StAR-related lipid transfer (START) domain containing 13 | 0.0315901 |
| NRP1 | neuropilin 1 | 0.0314526 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0312164 |
| HMGA2 | high mobility group AT-hook 2 | 0.0306081 |
| JAK1 | Janus kinase 1 | 0.030396 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | 0.030385 |
| ACTN1 | actinin, alpha 1 | 0.0303075 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0302526 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0299645 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0299091 |
| COL3A1 | collagen, type III, alpha 1 | 0.0298303 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.0298146 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0297099 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0293951 |
| HLA-B | major histocompatibility complex, class I, B | 0.0293258 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | 0.0291467 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0290391 |
| ITGAV | integrin, alpha V | 0.0290092 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0285653 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0676234 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0560261 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0481698 |
| NDRG1 | N-myc downstream regulated 1 | -0.0448175 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | -0.0437827 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0432981 |
| MMP1 | matrix metallopeptidase 1 | -0.0420006 |
| MMP12 | matrix metallopeptidase 12 | -0.0384253 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0362586 |
| GOLGA4 | golgin A4 | -0.0354298 |
| SGIP1 | SH3-domain GRB2-like (endophilin) interacting protein 1 | -0.0317922 |
| TMSB10 | thymosin beta 10 | -0.0299284 |
| ZNF292 | zinc finger protein 292 | -0.0278372 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.026145 |
| FAM13A | family with sequence similarity 13, member A | -0.0251153 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0226216 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | -0.022145 |
| NCKAP5 | NCK-associated protein 5 | -0.022005 |
| NGLY1 | N-glycanase 1 | -0.0201969 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0201756 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0188513 |
| AFF3 | AF4/FMR2 family, member 3 | -0.0181688 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0171848 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0166698 |
| SAMD3 | sterile alpha motif domain containing 3 | -0.0165365 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0164771 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.016304 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0152529 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0150875 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0149889 |
| ADM | adrenomedullin | -0.0148248 |
| ARF4 | ADP-ribosylation factor 4 | -0.0145332 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0145031 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0144993 |
| SRP54 | signal recognition particle 54kDa | -0.0138898 |
| TMEM165 | transmembrane protein 165 | -0.01383 |
| FTL | ferritin, light polypeptide | -0.0133019 |
| USP3 | ubiquitin specific peptidase 3 | -0.0132728 |
| FRMPD4 | FERM and PDZ domain containing 4 | -0.0132381 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.013222 |
| SUCO | SUN domain containing ossification factor | -0.0132012 |
| ATP13A3 | ATPase type 13A3 | -0.0129849 |
| NPTX1 | neuronal pentraxin I | -0.0127752 |
| FMNL2 | formin-like 2 | -0.0127091 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0124948 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.012446 |
| PFN1 | profilin 1 | -0.0121881 |
| S100A9 | S100 calcium binding protein A9 | -0.0120942 |
| PGM3 | phosphoglucomutase 3 | -0.0120078 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.011893 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0115797 |
| RPS19 | ribosomal protein S19 | -0.0115666 |
| EGR1 | early growth response 1 | -0.0114728 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0114346 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0114325 |
| CANX | calnexin | -0.0114113 |
| FGF5 | fibroblast growth factor 5 | -0.0113326 |
| SLC8A1 | solute carrier family 8 (sodium/calcium exchanger), member 1 | -0.0112281 |
| RNF145 | ring finger protein 145 | -0.0111887 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | -0.011161 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0111195 |
| FGFR1 | fibroblast growth factor receptor 1 | -0.0110935 |
| HELZ | helicase with zinc finger | -0.0109911 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | -0.0109264 |
| ARHGAP21 | Rho GTPase activating protein 21 | -0.0106857 |
| KMT2A | lysine (K)-specific methyltransferase 2A | -0.010416 |
| PLAG1 | pleiomorphic adenoma gene 1 | -0.0104074 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0103612 |
| TFG | TRK-fused gene | -0.0102197 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0102153 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0101125 |
| GLRX | glutaredoxin (thioltransferase) | -0.0101003 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0100112 |
| CIRSR | corepressor of RBPJ and splicing regulator | -0.00987066 |
| FOSL1 | FOS-like antigen 1 | -0.00980549 |
| PRELID2 | PRELI domain containing 2 | -0.00977813 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | -0.00964408 |
| YEATS2 | YEATS domain containing 2 | -0.00957667 |
| ATF4 | activating transcription factor 4 | -0.00950551 |
| STC2 | stanniocalcin 2 | -0.00947663 |
| DTNA | dystrobrevin, alpha | -0.0094226 |
| MORF4L2 | mortality factor 4 like 2 | -0.00935923 |
| VEGFA | vascular endothelial growth factor A | -0.00933979 |
| HSPB6 | heat shock protein, alpha-crystallin-related, B6 | -0.00930388 |
| COG6 | component of oligomeric golgi complex 6 | -0.00909761 |
| OS9 | osteosarcoma amplified 9, endoplasmic reticulum lectin | -0.00907485 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.00903721 |
| SEC61A1 | Sec61 alpha 1 subunit (S. cerevisiae) | -0.00895286 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | -0.00885756 |
| TMF1 | TATA element modulatory factor 1 | -0.0088343 |
| DNER | delta/notch-like EGF repeat containing | -0.00881364 |
| FST | follistatin | -0.00871797 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.00859362 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | -0.00855857 |
| RAI1 | retinoic acid induced 1 | -0.00855385 |
| FAM219A | family with sequence similarity 219, member A | -0.00853472 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.00850215 |
| CD109 | CD109 molecule | -0.00849214 |
| CCNL1 | cyclin L1 | -0.00841182 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.00836024 |
