Lidocaine Gene Set

Dataset CTD Gene-Chemical Interactions
Category physical interactions
Type chemical
Description The monocarboxylic acid amide resulting from the formal condensation of N,N-diethylglycine with 2,6-dimethylaniline. (Chemical Entities of Biological Interest Ontology, CHEBI_6456)
External Link http://ctdbase.org/detail.go?type=chem&acc=D008012
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Genes

45 genes/proteins interacting with the chemical Lidocaine from the curated CTD Gene-Chemical Interactions dataset.

Symbol Name
CALCA calcitonin-related polypeptide alpha
CASP3 caspase 3, apoptosis-related cysteine peptidase
CASP9 caspase 9, apoptosis-related cysteine peptidase
CCL2 chemokine (C-C motif) ligand 2
CXCL8 chemokine (C-X-C motif) ligand 8
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5
FOS FBJ murine osteosarcoma viral oncogene homolog
HMGB1 high mobility group box 1
IL13 interleukin 13
IL4 interleukin 4
IL6 interleukin 6
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit)
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2
KCNK18 potassium channel, two pore domain subfamily K, member 18
KCNK9 potassium channel, two pore domain subfamily K, member 9
KNG1 kininogen 1
LGALS1 lectin, galactoside-binding, soluble, 1
MAPK1 mitogen-activated protein kinase 1
MAPK3 mitogen-activated protein kinase 3
NR1I2 nuclear receptor subfamily 1, group I, member 2
ORM1 orosomucoid 1
ORM2 orosomucoid 2
POMC proopiomelanocortin
PRKCG protein kinase C, gamma
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
SCN4A sodium channel, voltage gated, type IV alpha subunit
SCN5A sodium channel, voltage gated, type V alpha subunit
SELL selectin L
SLC22A1 solute carrier family 22 (organic cation transporter), member 1
SLC22A16 solute carrier family 22 (organic cation/carnitine transporter), member 16
SLC22A2 solute carrier family 22 (organic cation transporter), member 2
SLC22A3 solute carrier family 22 (organic cation transporter), member 3
SLC22A4 solute carrier family 22 (organic cation/zwitterion transporter), member 4
SLC22A5 solute carrier family 22 (organic cation/carnitine transporter), member 5
SLC6A2 solute carrier family 6 (neurotransmitter transporter), member 2
SULT1A1 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
SULT1B1 sulfotransferase family, cytosolic, 1B, member 1
TGFA transforming growth factor, alpha
TNF tumor necrosis factor
TRPA1 transient receptor potential cation channel, subfamily A, member 1
TRPV1 transient receptor potential cation channel, subfamily V, member 1