| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ligustrazine perturbation in Hs 766T cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Ligustrazine_Hs 766T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FLNB | filamin B, beta | 0.201905 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.127226 |
| MEF2A | myocyte enhancer factor 2A | 0.115611 |
| SLC35F3 | solute carrier family 35, member F3 | 0.08754 |
| PODXL | podocalyxin-like | 0.0844637 |
| ITGA6 | integrin, alpha 6 | 0.0825185 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.079824 |
| PLEC | plectin | 0.074045 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0688216 |
| SPAG9 | sperm associated antigen 9 | 0.0682694 |
| NDRG1 | N-myc downstream regulated 1 | 0.0671068 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0659199 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.063566 |
| SLK | STE20-like kinase | 0.0606928 |
| MYO10 | myosin X | 0.0598594 |
| EZR | ezrin | 0.0587305 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0580602 |
| ANXA2 | annexin A2 | 0.0554797 |
| MYOF | myoferlin | 0.0548848 |
| SULF1 | sulfatase 1 | 0.0544632 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0535446 |
| HERC3 | HECT and RLD domain containing E3 ubiquitin protein ligase 3 | 0.0528903 |
| ADM | adrenomedullin | 0.0518646 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0503951 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0500713 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0496976 |
| CUL4B | cullin 4B | 0.0485121 |
| EFHD2 | EF-hand domain family, member D2 | 0.0480919 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0461619 |
| OGA | O-GlcNAcase | 0.0457282 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0456681 |
| ADAMTS16 | ADAM metallopeptidase with thrombospondin type 1 motif, 16 | 0.0456628 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0444894 |
| NAB1 | NGFI-A binding protein 1 (EGR1 binding protein 1) | 0.0444881 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.043859 |
| ARRDC3 | arrestin domain containing 3 | 0.0435251 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0421775 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0420667 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0419723 |
| GOLGA4 | golgin A4 | 0.0402179 |
| PTMA | prothymosin, alpha | 0.0397994 |
| ANLN | anillin, actin binding protein | 0.0390908 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0388301 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.037095 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0370245 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 0.0363361 |
| CANX | calnexin | 0.0351167 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0350653 |
| FAM13A | family with sequence similarity 13, member A | 0.0347052 |
| NUP58 | nucleoporin 58 | 0.0344867 |
| EMP1 | epithelial membrane protein 1 | 0.0343401 |
| SQLE | squalene epoxidase | 0.0340827 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | 0.0338652 |
| TAGLN2 | transgelin 2 | 0.0332807 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | 0.0332447 |
| FMNL2 | formin-like 2 | 0.0331235 |
| MATR3 | matrin 3 | 0.0329564 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0328375 |
| CNN3 | calponin 3, acidic | 0.0325693 |
| ZNF292 | zinc finger protein 292 | 0.0325118 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0323436 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.032333 |
| SLMAP | sarcolemma associated protein | 0.0323039 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0321386 |
| ATP13A3 | ATPase type 13A3 | 0.0321093 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0321061 |
| PFKFB2 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 | 0.0319259 |
| COPA | coatomer protein complex, subunit alpha | 0.0315719 |
| PGK1 | phosphoglycerate kinase 1 | 0.0314429 |
| RNF145 | ring finger protein 145 | 0.0314132 |
| SUCO | SUN domain containing ossification factor | 0.0311917 |
| KIAA1217 | KIAA1217 | 0.0310448 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0307872 |
| AHNAK | AHNAK nucleoprotein | 0.0307781 |
| LMO7 | LIM domain 7 | 0.0304115 |
| QKI | QKI, KH domain containing, RNA binding | 0.0303593 |
| CLU | clusterin | 0.0301855 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0300246 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0294915 |
| YOD1 | YOD1 deubiquitinase | 0.0291769 |
| GANAB | glucosidase, alpha; neutral AB | 0.0289615 |
| FAM162A | family with sequence similarity 162, member A | 0.0288103 |
| MSN | moesin | 0.0286965 |
| HELZ | helicase with zinc finger | 0.0286517 |
| KRT6A | keratin 6A, type II | 0.0286323 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0284919 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0282095 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0281783 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0281176 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0281082 |
| PPARG | peroxisome proliferator-activated receptor gamma | 0.0278323 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | 0.0278023 |
| ANXA1 | annexin A1 | 0.027689 |
| LRRFIP2 | leucine rich repeat (in FLII) interacting protein 2 | 0.0276674 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.027571 |
| INSIG2 | insulin induced gene 2 | 0.0271248 |
| COLEC11 | collectin sub-family member 11 | 0.027079 |
| KDM7A | lysine (K)-specific demethylase 7A | 0.0267462 |
| CEP170 | centrosomal protein 170kDa | 0.0266662 |
| CD47 | CD47 molecule | 0.0264517 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.180063 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.16395 |
| UBC | ubiquitin C | -0.11228 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0706968 |
| TMSB4X | thymosin beta 4, X-linked | -0.0646815 |
| HLA-B | major histocompatibility complex, class I, B | -0.0643458 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0636961 |
| INTS6 | integrator complex subunit 6 | -0.0633618 |
| FOXP1 | forkhead box P1 | -0.0572343 |
| RPS27A | ribosomal protein S27a | -0.0545865 |
| CNTNAP3 | contactin associated protein-like 3 | -0.0515776 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0467225 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0463974 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0455054 |
| TMSB10 | thymosin beta 10 | -0.0447295 |
| GNAS | GNAS complex locus | -0.0436019 |
| KLF5 | Kruppel-like factor 5 (intestinal) | -0.0426756 |
| MT1X | metallothionein 1X | -0.0421326 |
| IGF2 | insulin-like growth factor 2 | -0.0416632 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0415229 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0403946 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0395657 |
| HMGA2 | high mobility group AT-hook 2 | -0.0393274 |
| OSMR | oncostatin M receptor | -0.0372208 |
| HM13 | histocompatibility (minor) 13 | -0.0368628 |
| SMYD3 | SET and MYND domain containing 3 | -0.0367263 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0364297 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0357296 |
| DOK5 | docking protein 5 | -0.0349997 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0346321 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0345465 |
| ACTG1 | actin gamma 1 | -0.0342989 |
| RIGI | RNA sensor RIG-I | -0.0342219 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0336952 |
| S100A6 | S100 calcium binding protein A6 | -0.0330309 |
| MT2A | metallothionein 2A | -0.0326984 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0326315 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0322674 |
| CYB5R3 | cytochrome b5 reductase 3 | -0.032103 |
| B2M | beta-2-microglobulin | -0.0317895 |
| SULF2 | sulfatase 2 | -0.0317125 |
| TXNIP | thioredoxin interacting protein | -0.0315541 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0305303 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0304753 |
| RPS21 | ribosomal protein S21 | -0.0304448 |
| ATM | ATM serine/threonine kinase | -0.0298352 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0297492 |
| HDAC8 | histone deacetylase 8 | -0.0294361 |
| SOX7 | SRY (sex determining region Y)-box 7 | -0.0285956 |
| POTEF | POTE ankyrin domain family, member F | -0.0282847 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0281562 |
| MECOM | MDS1 and EVI1 complex locus | -0.028039 |
| CDK6 | cyclin-dependent kinase 6 | -0.027953 |
| HLA-E | major histocompatibility complex, class I, E | -0.0278739 |
| AOPEP | aminopeptidase O (putative) | -0.0272828 |
| IGFBP4 | insulin-like growth factor binding protein 4 | -0.0270307 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0269981 |
| RPLP1 | ribosomal protein, large, P1 | -0.0267407 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0265872 |
| CDK13 | cyclin-dependent kinase 13 | -0.0265764 |
| PLAT | plasminogen activator, tissue | -0.0263645 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 | -0.0263084 |
| NDE1 | nudE neurodevelopment protein 1 | -0.0262098 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0258663 |
| BPTF | bromodomain PHD finger transcription factor | -0.0258 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0250572 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0247316 |
| RPL34 | ribosomal protein L34 | -0.0244677 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0242499 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.024182 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0241386 |
| MYO9A | myosin IXA | -0.0240367 |
| ARHGAP29 | Rho GTPase activating protein 29 | -0.0239141 |
| S100A4 | S100 calcium binding protein A4 | -0.0237952 |
| TRIM56 | tripartite motif containing 56 | -0.0235775 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0235747 |
| EFNA5 | ephrin-A5 | -0.0235367 |
| ARB2A | ARB2 cotranscriptional regulator A | -0.0234867 |
| PMP22 | peripheral myelin protein 22 | -0.0234466 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0234015 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.023328 |
| MT1E | metallothionein 1E | -0.0229842 |
| EP300 | E1A binding protein p300 | -0.0228953 |
| IFI44L | interferon-induced protein 44-like | -0.0228167 |
| LRRC8A | leucine rich repeat containing 8 family, member A | -0.0227049 |
| EGR1 | early growth response 1 | -0.022638 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.022603 |
| WNT2B | wingless-type MMTV integration site family, member 2B | -0.0225325 |
| SMG6 | SMG6 nonsense mediated mRNA decay factor | -0.0224543 |
| ATXN1 | ataxin 1 | -0.0224458 |
| PDGFB | platelet-derived growth factor beta polypeptide | -0.0223735 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0223692 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0222004 |
| LUZP1 | leucine zipper protein 1 | -0.0219922 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.0217654 |
| RPS24 | ribosomal protein S24 | -0.0217529 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0216562 |
| MEIS2 | Meis homeobox 2 | -0.0216465 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0215912 |
| SP100 | SP100 nuclear antigen | -0.0215906 |
