| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ligustrazine perturbation in KATO III cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Ligustrazine_KATO III drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.280054 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.137322 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.111632 |
| AHNAK | AHNAK nucleoprotein | 0.090227 |
| HYOU1 | hypoxia up-regulated 1 | 0.087687 |
| CANX | calnexin | 0.0866247 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0803 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0786199 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0776695 |
| TES | testin LIM domain protein | 0.0667821 |
| GOLGA4 | golgin A4 | 0.0661431 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0653797 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0610572 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.059745 |
| FAM13A | family with sequence similarity 13, member A | 0.0596342 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0588599 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0585902 |
| KRT18 | keratin 18, type I | 0.058408 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0575925 |
| KRT17 | keratin 17, type I | 0.057001 |
| CALR | calreticulin | 0.0555194 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0522233 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | 0.0510964 |
| IARS1 | isoleucyl-tRNA synthetase 1 | 0.0509781 |
| FGFR2 | fibroblast growth factor receptor 2 | 0.0508992 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0476013 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0475329 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0474305 |
| XPO1 | exportin 1 | 0.0468092 |
| ANXA2 | annexin A2 | 0.0457014 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.045293 |
| OGA | O-GlcNAcase | 0.0450212 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0448993 |
| NDRG1 | N-myc downstream regulated 1 | 0.0443984 |
| H1-0 | H1.0 linker histone | 0.0435804 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.04281 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0427679 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0427164 |
| TRIM2 | tripartite motif containing 2 | 0.0420618 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0410592 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.0405246 |
| HELZ | helicase with zinc finger | 0.0403636 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0401353 |
| PLEC | plectin | 0.0396225 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | 0.0385723 |
| CCNY | cyclin Y | 0.0383012 |
| ENO1 | enolase 1, (alpha) | 0.0375737 |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) | 0.0374435 |
| SEC23B | Sec23 homolog B (S. cerevisiae) | 0.0374087 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0373845 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0369335 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0355714 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0354931 |
| ZNF292 | zinc finger protein 292 | 0.0354434 |
| NUP58 | nucleoporin 58 | 0.0346621 |
| DNAJB11 | DnaJ (Hsp40) homolog, subfamily B, member 11 | 0.0344947 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.034422 |
| PCBP2 | poly(rC) binding protein 2 | 0.034273 |
| ESRP1 | epithelial splicing regulatory protein 1 | 0.0340818 |
| NBAS | neuroblastoma amplified sequence | 0.0340693 |
| TM9SF3 | transmembrane 9 superfamily member 3 | 0.0339037 |
| KLHL29 | kelch-like family member 29 | 0.0338309 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0335942 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0335332 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0333735 |
| MUC17 | mucin 17, cell surface associated | 0.0329369 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0328174 |
| DSPP | dentin sialophosphoprotein | 0.0327677 |
| ITGA6 | integrin, alpha 6 | 0.0327163 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0324848 |
| SEC61A1 | Sec61 alpha 1 subunit (S. cerevisiae) | 0.0322914 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0319769 |
| KRT19 | keratin 19, type I | 0.0319534 |
| YTHDC1 | YTH domain containing 1 | 0.0317563 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0312715 |
| RBM33 | RNA binding motif protein 33 | 0.0312595 |
| RLIM | ring finger protein, LIM domain interacting | 0.0310447 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0306303 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0296927 |
| PGK1 | phosphoglycerate kinase 1 | 0.0292197 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.029206 |
| MATR3 | matrin 3 | 0.0290916 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0285468 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.028529 |
| DDX6 | DEAD (Asp-Glu-Ala-Asp) box helicase 6 | 0.0282457 |
| PTK2 | protein tyrosine kinase 2 | 0.0281953 |
| AFTPH | aftiphilin | 0.0279726 |
| SPAG9 | sperm associated antigen 9 | 0.0279198 |
| LYZ | lysozyme | 0.0277608 |
| SERINC1 | serine incorporator 1 | 0.0277167 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0276702 |
| ARCN1 | archain 1 | 0.0275533 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0274778 |
| SRP54 | signal recognition particle 54kDa | 0.0274487 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0273625 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0273347 |
| CCDC47 | coiled-coil domain containing 47 | 0.0271956 |
| ANXA11 | annexin A11 | 0.0271841 |
| CLINT1 | clathrin interactor 1 | 0.0271751 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.027161 |
| Symbol | Name | Standardized Value |
|---|---|---|
| LMO7 | LIM domain 7 | -0.0882083 |
| TMC5 | transmembrane channel-like 5 | -0.0817846 |
| TMSB10 | thymosin beta 10 | -0.0742828 |
| RPS6 | ribosomal protein S6 | -0.0660461 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0615989 |
| EHBP1 | EH domain binding protein 1 | -0.0577125 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0552642 |
| B2M | beta-2-microglobulin | -0.0544071 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0498094 |
| BPTF | bromodomain PHD finger transcription factor | -0.047052 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0464976 |
| SLC38A2 | solute carrier family 38, member 2 | -0.044216 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0435406 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0422915 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0414636 |
| RPS19 | ribosomal protein S19 | -0.0401872 |
| EFNA5 | ephrin-A5 | -0.0366074 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0359412 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0352156 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0352151 |
| S100P | S100 calcium binding protein P | -0.0338644 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0329304 |
| RPL28 | ribosomal protein L28 | -0.0328838 |
| RPS2 | ribosomal protein S2 | -0.0320002 |
| RPS3 | ribosomal protein S3 | -0.031791 |
| RNF213 | ring finger protein 213 | -0.0314769 |
| ASPH | aspartate beta-hydroxylase | -0.0312685 |
| RPLP1 | ribosomal protein, large, P1 | -0.0303469 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.02991 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | -0.0296282 |
| RPL9 | ribosomal protein L9 | -0.0294135 |
| MYO1D | myosin ID | -0.0289647 |
| HLA-B | major histocompatibility complex, class I, B | -0.0283999 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.0281803 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0276641 |
| ATM | ATM serine/threonine kinase | -0.027555 |
| H3-3B | H3.3 histone B | -0.0270468 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | -0.0267048 |
| ACTG1 | actin gamma 1 | -0.0265258 |
| MTUS1 | microtubule associated tumor suppressor 1 | -0.0265027 |
| TMEM45B | transmembrane protein 45B | -0.0265018 |
| INTS6 | integrator complex subunit 6 | -0.0264115 |
| RAD51B | RAD51 paralog B | -0.026259 |
| PTMA | prothymosin, alpha | -0.0259168 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0252501 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0252191 |
| YAP1 | Yes-associated protein 1 | -0.0249599 |
| OGDH | oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) | -0.0249031 |
| S100A11 | S100 calcium binding protein A11 | -0.0248408 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0247145 |
| PHF14 | PHD finger protein 14 | -0.0246926 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0245849 |
| C6ORF132 | chromosome 6 open reading frame 132 | -0.0245396 |
| C6ORF62 | chromosome 6 open reading frame 62 | -0.0244895 |
| RBBP6 | retinoblastoma binding protein 6 | -0.0244795 |
| RPS25 | ribosomal protein S25 | -0.0244435 |
| TNRC6B | trinucleotide repeat containing 6B | -0.024327 |
| LIMA1 | LIM domain and actin binding 1 | -0.0242246 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.024092 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0240872 |
| PLSCR1 | phospholipid scramblase 1 | -0.0239202 |
| SLCO1B3-SLCO1B7 | SLCO1B3-SLCO1B7 readthrough | -0.0237817 |
| GPATCH8 | G patch domain containing 8 | -0.0237024 |
| CASK | calcium/calmodulin-dependent serine protein kinase (MAGUK family) | -0.0237021 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0236749 |
| RPL18 | ribosomal protein L18 | -0.0235523 |
| TXNRD1 | thioredoxin reductase 1 | -0.0234967 |
| WWC1 | WW and C2 domain containing 1 | -0.023203 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.023081 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0230174 |
| RPL26 | ribosomal protein L26 | -0.0227619 |
| RPS8 | ribosomal protein S8 | -0.0227526 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0225881 |
| ESF1 | ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae) | -0.0225526 |
| RPS16 | ribosomal protein S16 | -0.0225444 |
| PRAG1 | PEAK1 related, kinase-activating pseudokinase 1 | -0.0225031 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0224118 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0221753 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0221053 |
| VMP1 | vacuole membrane protein 1 | -0.0221029 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0220862 |
| PCSK5 | proprotein convertase subtilisin/kexin type 5 | -0.0220173 |
| EFNB2 | ephrin-B2 | -0.0218815 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | -0.0217472 |
| MUC1 | mucin 1, cell surface associated | -0.0216844 |
| ZFP36L2 | ZFP36 ring finger protein-like 2 | -0.0216672 |
| MTAP | methylthioadenosine phosphorylase | -0.0214901 |
| RPS21 | ribosomal protein S21 | -0.0213045 |
| LLGL2 | lethal giant larvae homolog 2 (Drosophila) | -0.0212633 |
| RNF43 | ring finger protein 43 | -0.0212246 |
| LRRTM4 | leucine rich repeat transmembrane neuronal 4 | -0.0211868 |
| CDK6 | cyclin-dependent kinase 6 | -0.0210762 |
| LMNA | lamin A/C | -0.0210254 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.021018 |
| ZC3H12B | zinc finger CCCH-type containing 12B | -0.0209107 |
| SHB | Src homology 2 domain containing adaptor protein B | -0.0208754 |
| SEC61G | Sec61 gamma subunit | -0.0207987 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | -0.0207646 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0207393 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0205495 |
