| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ligustrazine perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Ligustrazine_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MYH9 | myosin, heavy chain 9, non-muscle | 0.194965 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.165936 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.160668 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.136463 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.126522 |
| NAV2 | neuron navigator 2 | 0.122272 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.11515 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0931337 |
| PDE10A | phosphodiesterase 10A | 0.0881147 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0870534 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.0869762 |
| CADM1 | cell adhesion molecule 1 | 0.0772261 |
| ZNF292 | zinc finger protein 292 | 0.0709657 |
| GOLGA4 | golgin A4 | 0.0699409 |
| ENO1 | enolase 1, (alpha) | 0.0683161 |
| SPAG9 | sperm associated antigen 9 | 0.0676893 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0664025 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0638132 |
| ADM | adrenomedullin | 0.0636568 |
| MYOF | myoferlin | 0.0621197 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0606041 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0603752 |
| HELZ | helicase with zinc finger | 0.0584294 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0575036 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0572613 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0569699 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0568342 |
| PRELID2 | PRELI domain containing 2 | 0.0562152 |
| VEGFA | vascular endothelial growth factor A | 0.0557497 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0552163 |
| PCBP2 | poly(rC) binding protein 2 | 0.0546613 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.054356 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0535464 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0526978 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0520221 |
| FMNL2 | formin-like 2 | 0.0509277 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0505749 |
| ATP13A3 | ATPase type 13A3 | 0.0499048 |
| SEPTIN9 | septin 9 | 0.0489438 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0486218 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0477645 |
| MSN | moesin | 0.0477551 |
| ARRDC3 | arrestin domain containing 3 | 0.0471623 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0465864 |
| MMP12 | matrix metallopeptidase 12 | 0.0461415 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0460392 |
| PLIN2 | perilipin 2 | 0.0458442 |
| CEP250 | centrosomal protein 250kDa | 0.0458343 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0452342 |
| FLOT1 | flotillin 1 | 0.0451386 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0434956 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0434613 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0425009 |
| DST | dystonin | 0.0424671 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0409946 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0409797 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | 0.0404806 |
| AMPD3 | adenosine monophosphate deaminase 3 | 0.0400928 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.039985 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0389838 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0383163 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0376633 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0368589 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0358909 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0355731 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0354843 |
| SNX9 | sorting nexin 9 | 0.0353827 |
| OGA | O-GlcNAcase | 0.0349368 |
| TRPM7 | transient receptor potential cation channel, subfamily M, member 7 | 0.0338003 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0335366 |
| MYO1B | myosin IB | 0.0328441 |
| STC1 | stanniocalcin 1 | 0.0324993 |
| NGLY1 | N-glycanase 1 | 0.0324528 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.03223 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0321973 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0318329 |
| WDFY1 | WD repeat and FYVE domain containing 1 | 0.0318006 |
| JMJD1C | jumonji domain containing 1C | 0.0305367 |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 | 0.0302215 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0301751 |
| NDRG1 | N-myc downstream regulated 1 | 0.0301436 |
| FRMPD4 | FERM and PDZ domain containing 4 | 0.0300094 |
| ARFGEF3 | ARFGEF family member 3 | 0.0299858 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0298041 |
| RAI1 | retinoic acid induced 1 | 0.0297919 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0296077 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | 0.0296035 |
| YEATS2 | YEATS domain containing 2 | 0.0295195 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0294797 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0290342 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.028994 |
| FLNB | filamin B, beta | 0.0289379 |
| CD109 | CD109 molecule | 0.0288116 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0287777 |
| CNNM2 | cyclin and CBS domain divalent metal cation transport mediator 2 | 0.0282743 |
| ANXA5 | annexin A5 | 0.0282439 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0281722 |
| FNIP1 | folliculin interacting protein 1 | 0.0281671 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0276607 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0274623 |
| Symbol | Name | Standardized Value |
|---|---|---|
| BICC1 | BicC family RNA binding protein 1 | -0.185478 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.170742 |
| VCL | vinculin | -0.144606 |
| GLIS3 | GLIS family zinc finger 3 | -0.125773 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0902352 |
| HLA-B | major histocompatibility complex, class I, B | -0.088031 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0844556 |
| EGR1 | early growth response 1 | -0.0745333 |
| NABP1 | nucleic acid binding protein 1 | -0.0619308 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.059697 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0592465 |
| PALLD | palladin, cytoskeletal associated protein | -0.056097 |
| TMSB10 | thymosin beta 10 | -0.055048 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0540269 |
| HMGA2 | high mobility group AT-hook 2 | -0.0499814 |
| KYNU | kynureninase | -0.0499467 |
| FTL | ferritin, light polypeptide | -0.0488073 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0488029 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0472855 |
| RIGI | RNA sensor RIG-I | -0.0461938 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0447215 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.0442446 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0441086 |
| IER3 | immediate early response 3 | -0.0411474 |
| VIM | vimentin | -0.0395634 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0394896 |
| ACTG1 | actin gamma 1 | -0.0390956 |
| DCBLD1 | discoidin, CUB and LCCL domain containing 1 | -0.0389692 |
| HLA-A | major histocompatibility complex, class I, A | -0.0381627 |
| OSMR | oncostatin M receptor | -0.0375088 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0359153 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0347691 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0340294 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0330694 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0329773 |
| ANKS1B | ankyrin repeat and sterile alpha motif domain containing 1B | -0.0320888 |
| EPAS1 | endothelial PAS domain protein 1 | -0.031245 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.031101 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0300222 |
| THBS1 | thrombospondin 1 | -0.0300129 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0298653 |
| HDAC8 | histone deacetylase 8 | -0.0296113 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0288449 |
| GNAS | GNAS complex locus | -0.0287587 |
| BPTF | bromodomain PHD finger transcription factor | -0.028696 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0283844 |
| ZBTB38 | zinc finger and BTB domain containing 38 | -0.0276391 |
| GOPC | golgi-associated PDZ and coiled-coil motif containing | -0.0275368 |
| EHBP1 | EH domain binding protein 1 | -0.0274645 |
| INTS6 | integrator complex subunit 6 | -0.0274008 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0269345 |
| PMP22 | peripheral myelin protein 22 | -0.0262668 |
| SMYD3 | SET and MYND domain containing 3 | -0.0258424 |
| LOX | lysyl oxidase | -0.0258142 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0257282 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0255934 |
| RPS19 | ribosomal protein S19 | -0.024921 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0247408 |
| HLA-E | major histocompatibility complex, class I, E | -0.0245757 |
| GPC6 | glypican 6 | -0.0243866 |
| JAK2 | Janus kinase 2 | -0.0243705 |
| NTN4 | netrin 4 | -0.0238189 |
| MT2A | metallothionein 2A | -0.0236601 |
| TUT7 | terminal uridylyl transferase 7 | -0.0233431 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0232525 |
| SMAD3 | SMAD family member 3 | -0.0231383 |
| TAPBP | TAP binding protein (tapasin) | -0.0227024 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0226569 |
| VMP1 | vacuole membrane protein 1 | -0.0223252 |
| TRIM55 | tripartite motif containing 55 | -0.0223179 |
| DIAPH2 | diaphanous-related formin 2 | -0.0219309 |
| CTSD | cathepsin D | -0.0216823 |
| PDLIM5 | PDZ and LIM domain 5 | -0.021606 |
| RASAL2 | RAS protein activator like 2 | -0.0215704 |
| TRIM22 | tripartite motif containing 22 | -0.0213363 |
| FAM20C | family with sequence similarity 20, member C | -0.021011 |
| RPS3 | ribosomal protein S3 | -0.0206484 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0204239 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | -0.0204117 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.0203534 |
| NRP1 | neuropilin 1 | -0.0202443 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | -0.0201169 |
| TUBB | tubulin, beta class I | -0.0199494 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0199208 |
| MORF4L2 | mortality factor 4 like 2 | -0.0198067 |
| KLF12 | Kruppel-like factor 12 | -0.0197726 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0196296 |
| MX2 | MX dynamin-like GTPase 2 | -0.0195714 |
| RPL32 | ribosomal protein L32 | -0.0194088 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0193944 |
| TRIM38 | tripartite motif containing 38 | -0.0193363 |
| GREM1 | gremlin 1, DAN family BMP antagonist | -0.0192302 |
| GLIPR1 | GLI pathogenesis-related 1 | -0.0191851 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0191804 |
| WDR70 | WD repeat domain 70 | -0.0191208 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0189169 |
| TLE4 | transducin-like enhancer of split 4 | -0.0187078 |
| RPS14 | ribosomal protein S14 | -0.0186489 |
| TNNC1 | troponin C type 1 (slow) | -0.0186425 |
| NGF | nerve growth factor (beta polypeptide) | -0.0185714 |
