| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ligustrazine perturbation in SW 1271 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Ligustrazine_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NUP58 | nucleoporin 58 | 0.0586326 |
| ZNF292 | zinc finger protein 292 | 0.0440474 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0355039 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0348071 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0342981 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0301987 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0295528 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0288661 |
| ECT2 | epithelial cell transforming 2 | 0.0285267 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0276785 |
| HELZ | helicase with zinc finger | 0.0270378 |
| CEP250 | centrosomal protein 250kDa | 0.026772 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0261031 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0260088 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0258806 |
| DTNA | dystrobrevin, alpha | 0.0250498 |
| OLA1 | Obg-like ATPase 1 | 0.0240458 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.024012 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.023419 |
| RANBP9 | RAN binding protein 9 | 0.0233585 |
| RBM33 | RNA binding motif protein 33 | 0.0230263 |
| NUP153 | nucleoporin 153kDa | 0.0227255 |
| PTCD3 | pentatricopeptide repeat domain 3 | 0.0224153 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0222913 |
| RARS1 | arginyl-tRNA synthetase 1 | 0.021971 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0219597 |
| DERA | deoxyribose-phosphate aldolase (putative) | 0.021358 |
| SFXN1 | sideroflexin 1 | 0.0209663 |
| ETNK1 | ethanolamine kinase 1 | 0.0209111 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | 0.0207735 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0207041 |
| DCP2 | decapping mRNA 2 | 0.0205998 |
| SNX14 | sorting nexin 14 | 0.0204497 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0204204 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0202856 |
| CANX | calnexin | 0.0202357 |
| TPR | translocated promoter region, nuclear basket protein | 0.0201038 |
| LUC7L2 | LUC7-like 2 (S. cerevisiae) | 0.0200151 |
| AAGAB | alpha- and gamma-adaptin binding protein | 0.0199549 |
| SS18 | synovial sarcoma translocation, chromosome 18 | 0.0199423 |
| CUL4B | cullin 4B | 0.0198299 |
| NR1D2 | nuclear receptor subfamily 1, group D, member 2 | 0.0197807 |
| AHCTF1 | AT hook containing transcription factor 1 | 0.0197452 |
| USP37 | ubiquitin specific peptidase 37 | 0.0197202 |
| TCEA1 | transcription elongation factor A (SII), 1 | 0.019673 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0196414 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0196138 |
| UBE3A | ubiquitin protein ligase E3A | 0.0193567 |
| ARRDC3 | arrestin domain containing 3 | 0.0192861 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0191781 |
| ANP32B | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B | 0.0190156 |
| SKIC3 | SKI3 subunit of superkiller complex | 0.0189686 |
| MIS18BP1 | MIS18 binding protein 1 | 0.018815 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | 0.0185109 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.018493 |
| WAPL | WAPL cohesin release factor | 0.0184799 |
| MIER1 | mesoderm induction early response 1, transcriptional regulator | 0.0184313 |
| RIMKLB | ribosomal modification protein rimK-like family member B | 0.0184036 |
| FLNB | filamin B, beta | 0.0183541 |
| SBNO1 | strawberry notch homolog 1 (Drosophila) | 0.0182532 |
| HIPK1 | homeodomain interacting protein kinase 1 | 0.0182125 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0179915 |
| DDB1 | damage-specific DNA binding protein 1, 127kDa | 0.0178294 |
| RAB8B | RAB8B, member RAS oncogene family | 0.0176679 |
| RACGAP1 | Rac GTPase activating protein 1 | 0.0175465 |
| PCMT1 | protein-L-isoaspartate (D-aspartate) O-methyltransferase | 0.0175335 |
| FAM168B | family with sequence similarity 168, member B | 0.0172697 |
| FAM117B | family with sequence similarity 117, member B | 0.0171574 |
| USP3 | ubiquitin specific peptidase 3 | 0.0171092 |
| NGLY1 | N-glycanase 1 | 0.0171006 |
| CEP70 | centrosomal protein 70kDa | 0.0170181 |
| ATP13A3 | ATPase type 13A3 | 0.0169815 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0168586 |
| RSRC1 | arginine/serine-rich coiled-coil 1 | 0.0168207 |
| TNRC6B | trinucleotide repeat containing 6B | 0.0167195 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0166447 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.0165569 |
| RREB1 | ras responsive element binding protein 1 | 0.0164911 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.016451 |
| RRAS2 | related RAS viral (r-ras) oncogene homolog 2 | 0.0164373 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0163511 |
| YAP1 | Yes-associated protein 1 | 0.0160916 |
| HSPA4 | heat shock 70kDa protein 4 | 0.0160014 |
| PDE10A | phosphodiesterase 10A | 0.015921 |
| AUH | AU RNA binding protein/enoyl-CoA hydratase | 0.0158731 |
| RBM26 | RNA binding motif protein 26 | 0.015806 |
| CBX1 | chromobox homolog 1 | 0.0157717 |
| TFG | TRK-fused gene | 0.015654 |
| MRE11 | MRE11 homolog, double strand break repair nuclease | 0.0156497 |
| STT3B | STT3B, subunit of the oligosaccharyltransferase complex (catalytic) | 0.0156166 |
| UHMK1 | U2AF homology motif (UHM) kinase 1 | 0.0156152 |
| HMGN3 | high mobility group nucleosomal binding domain 3 | 0.0155491 |
| SEPTIN2 | septin 2 | 0.0154823 |
| EED | embryonic ectoderm development | 0.0153855 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.015374 |
| RPRD1B | regulation of nuclear pre-mRNA domain containing 1B | 0.0153594 |
| TP53BP1 | tumor protein p53 binding protein 1 | 0.0153521 |
| DNAJB11 | DnaJ (Hsp40) homolog, subfamily B, member 11 | 0.0153316 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0153207 |
| SEC63 | SEC63 homolog (S. cerevisiae) | 0.0153035 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.47596 |
| VIM | vimentin | -0.155176 |
| TMSB10 | thymosin beta 10 | -0.0815318 |
| CD44 | CD44 molecule (Indian blood group) | -0.0756841 |
| PTMA | prothymosin, alpha | -0.0673021 |
| LOC112694756 | uncharaterized LOC112694756 | -0.06282 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.056245 |
| GNAS | GNAS complex locus | -0.0554175 |
| FMNL2 | formin-like 2 | -0.0487268 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0459731 |
| UBC | ubiquitin C | -0.0459508 |
| ANGPTL4 | angiopoietin-like 4 | -0.0441235 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0428639 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0425402 |
| PRKCA | protein kinase C, alpha | -0.0411659 |
| UBB | ubiquitin B | -0.0406951 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0406479 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0386128 |
| BPTF | bromodomain PHD finger transcription factor | -0.0378739 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0377691 |
| IGF2 | insulin-like growth factor 2 | -0.0366743 |
| HMGA2 | high mobility group AT-hook 2 | -0.0360411 |
| OSMR | oncostatin M receptor | -0.0356517 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0353827 |
| TPM4 | tropomyosin 4 | -0.0352846 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0342568 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.0332286 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0332014 |
| PKM | pyruvate kinase, muscle | -0.0329251 |
| POTEF | POTE ankyrin domain family, member F | -0.0327967 |
| ACTG1 | actin gamma 1 | -0.0327899 |
| SQSTM1 | sequestosome 1 | -0.0318913 |
| LDHA | lactate dehydrogenase A | -0.0318534 |
| MAP3K20 | mitogen-activated protein kinase kinase kinase 20 | -0.0318381 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0309176 |
| ATXN1 | ataxin 1 | -0.0308733 |
| MED13 | mediator complex subunit 13 | -0.0308555 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0308177 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0304508 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0302612 |
| EFNA5 | ephrin-A5 | -0.0302463 |
| SVIL | supervillin | -0.0300124 |
| NF1 | neurofibromin 1 | -0.0299341 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0298845 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0298055 |
| B2M | beta-2-microglobulin | -0.0295088 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0292471 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0289499 |
| RPLP1 | ribosomal protein, large, P1 | -0.028538 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0283743 |
| YBX3 | Y box binding protein 3 | -0.0283094 |
| ANXA2 | annexin A2 | -0.0278876 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.027862 |
| PTK2 | protein tyrosine kinase 2 | -0.027783 |
| EGR1 | early growth response 1 | -0.0260397 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0259433 |
| RIGI | RNA sensor RIG-I | -0.0257543 |
| CAVIN1 | caveolae associated protein 1 | -0.0255873 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0255223 |
| RPS8 | ribosomal protein S8 | -0.0254393 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.0253675 |
| RNF213 | ring finger protein 213 | -0.0253169 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0252233 |
| S100A10 | S100 calcium binding protein A10 | -0.0251707 |
| S100A9 | S100 calcium binding protein A9 | -0.0251203 |
| CCNI | cyclin I | -0.02498 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0246693 |
| NT5E | 5'-nucleotidase, ecto (CD73) | -0.0245107 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0243639 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0238625 |
| CLIP1 | CAP-GLY domain containing linker protein 1 | -0.0236867 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.023605 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0232716 |
| SETX | senataxin | -0.0231318 |
| FTL | ferritin, light polypeptide | -0.0231053 |
| ZBTB7A | zinc finger and BTB domain containing 7A | -0.0228638 |
| FER | fer (fps/fes related) tyrosine kinase | -0.0228465 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0227711 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0225013 |
| EGFR | epidermal growth factor receptor | -0.0223957 |
| RPLP0 | ribosomal protein, large, P0 | -0.0223887 |
| MYO9A | myosin IXA | -0.0223372 |
| RRBP1 | ribosome binding protein 1 | -0.0223049 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0221418 |
| DST | dystonin | -0.0221109 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0220713 |
| INTS6 | integrator complex subunit 6 | -0.0220705 |
| NALCN | sodium leak channel, non selective | -0.0219785 |
| CDK6 | cyclin-dependent kinase 6 | -0.0218477 |
| RPS20 | ribosomal protein S20 | -0.0215212 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0215127 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0214344 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0212689 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0211957 |
| RPS14 | ribosomal protein S14 | -0.021092 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0210856 |
| SCAPER | S-phase cyclin A-associated protein in the ER | -0.020999 |
| MT1X | metallothionein 1X | -0.0209673 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.020934 |
| MT2A | metallothionein 2A | -0.0208828 |
