| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Lipoic acid perturbation in A-172 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Lipoic acid_A-172 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.133924 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.119843 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.101654 |
| HDAC9 | histone deacetylase 9 | 0.089787 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0875602 |
| PLAT | plasminogen activator, tissue | 0.0860179 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.0775777 |
| EGFR | epidermal growth factor receptor | 0.0755555 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0737347 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0657844 |
| NAV2 | neuron navigator 2 | 0.0652139 |
| CALR | calreticulin | 0.0618675 |
| PODXL | podocalyxin-like | 0.0608257 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0534635 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0503529 |
| GOLGB1 | golgin B1 | 0.0476108 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0471556 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0468509 |
| TPM3 | tropomyosin 3 | 0.0458999 |
| TPM4 | tropomyosin 4 | 0.0444612 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0438564 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0429598 |
| MYADM | myeloid-associated differentiation marker | 0.0424414 |
| BCL2L1 | BCL2-like 1 | 0.0415794 |
| ERBIN | erbb2 interacting protein | 0.0404599 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0386511 |
| GOLGA4 | golgin A4 | 0.038383 |
| SEPTIN9 | septin 9 | 0.0382984 |
| PRKCE | protein kinase C, epsilon | 0.0381253 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0377087 |
| FNDC3B | fibronectin type III domain containing 3B | 0.035441 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | 0.0353853 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0353756 |
| SMYD3 | SET and MYND domain containing 3 | 0.0353404 |
| PRKAG2 | protein kinase, AMP-activated, gamma 2 non-catalytic subunit | 0.0349985 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0347713 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.034008 |
| E2F7 | E2F transcription factor 7 | 0.0339967 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0337854 |
| OPTN | optineurin | 0.0336786 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0335831 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.0335233 |
| CDH13 | cadherin 13 | 0.0333806 |
| CD99 | CD99 molecule | 0.0312668 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0310306 |
| NIBAN1 | niban apoptosis regulator 1 | 0.0309234 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0307198 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0306113 |
| ASPH | aspartate beta-hydroxylase | 0.0301378 |
| ATP13A3 | ATPase type 13A3 | 0.0301076 |
| RND3 | Rho family GTPase 3 | 0.0299261 |
| IL6ST | interleukin 6 signal transducer | 0.0294825 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0294347 |
| DST | dystonin | 0.0290602 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0290195 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0281773 |
| CAMSAP2 | calmodulin regulated spectrin-associated protein family, member 2 | 0.0276761 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0272172 |
| SETX | senataxin | 0.0270563 |
| LDHA | lactate dehydrogenase A | 0.0268374 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0267501 |
| TXNRD1 | thioredoxin reductase 1 | 0.0266868 |
| VOPP1 | vesicular, overexpressed in cancer, prosurvival protein 1 | 0.0266698 |
| ANXA2 | annexin A2 | 0.0265541 |
| BTBD10 | BTB (POZ) domain containing 10 | 0.0262685 |
| MSN | moesin | 0.0261581 |
| BPTF | bromodomain PHD finger transcription factor | 0.0258049 |
| DSPP | dentin sialophosphoprotein | 0.0256531 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0254695 |
| ICE1 | interactor of little elongation complex ELL subunit 1 | 0.0254331 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.0253798 |
| ANKRD30B | ankyrin repeat domain 30B | 0.0253793 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0251941 |
| B2M | beta-2-microglobulin | 0.0251277 |
| L1CAM | L1 cell adhesion molecule | 0.0250517 |
| MED13 | mediator complex subunit 13 | 0.0250215 |
| LYST | lysosomal trafficking regulator | 0.0249839 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0249631 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0249235 |
| SET | SET nuclear proto-oncogene | 0.0247326 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0247154 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.0246807 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0246697 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0246601 |
| AFF3 | AF4/FMR2 family, member 3 | 0.0245202 |
| DOCK9 | dedicator of cytokinesis 9 | 0.0244344 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.0243237 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.0241378 |
| ASTN2 | astrotactin 2 | 0.0239365 |
| XPC | xeroderma pigmentosum, complementation group C | 0.0238709 |
| PPM1D | protein phosphatase, Mg2+/Mn2+ dependent, 1D | 0.0238097 |
| AAK1 | AP2 associated kinase 1 | 0.0237988 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0237867 |
| XKR6 | XK, Kell blood group complex subunit-related family, member 6 | 0.0236829 |
| REST | RE1-silencing transcription factor | 0.0235974 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0235939 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0230096 |
| JMJD1C | jumonji domain containing 1C | 0.0229349 |
| NEK7 | NIMA-related kinase 7 | 0.0229059 |
| CD44 | CD44 molecule (Indian blood group) | 0.0228777 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.149317 |
| TMSB10 | thymosin beta 10 | -0.142914 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.123274 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.122344 |
| FBN1 | fibrillin 1 | -0.101031 |
| COL8A1 | collagen, type VIII, alpha 1 | -0.0939862 |
| RIGI | RNA sensor RIG-I | -0.0886168 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0871762 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | -0.0830577 |
| NAV1 | neuron navigator 1 | -0.0819108 |
| AHNAK | AHNAK nucleoprotein | -0.0816171 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0791069 |
| THBS2 | thrombospondin 2 | -0.0779206 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0760833 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0746183 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0745475 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0743438 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0735792 |
| MEIS2 | Meis homeobox 2 | -0.0657812 |
| COL5A2 | collagen, type V, alpha 2 | -0.064866 |
| COL5A1 | collagen, type V, alpha 1 | -0.0647411 |
| MT2A | metallothionein 2A | -0.0640344 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.06351 |
| FN1 | fibronectin 1 | -0.0604434 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0594982 |
| PRSS23 | protease, serine, 23 | -0.0544827 |
| TMSB4X | thymosin beta 4, X-linked | -0.0542442 |
| FSTL1 | follistatin-like 1 | -0.0541074 |
| COL1A2 | collagen, type I, alpha 2 | -0.051307 |
| PGK1 | phosphoglycerate kinase 1 | -0.0502139 |
| LOXL2 | lysyl oxidase-like 2 | -0.0502112 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0479283 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0463641 |
| MSI2 | musashi RNA-binding protein 2 | -0.0459591 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0450434 |
| MX2 | MX dynamin-like GTPase 2 | -0.0449065 |
| PTMA | prothymosin, alpha | -0.0382473 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0378036 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0377603 |
| RPS6KC1 | ribosomal protein S6 kinase, 52kDa, polypeptide 1 | -0.0370318 |
| FNDC3A | fibronectin type III domain containing 3A | -0.036894 |
| DIRAS3 | DIRAS family, GTP-binding RAS-like 3 | -0.0367642 |
| SLC8A1 | solute carrier family 8 (sodium/calcium exchanger), member 1 | -0.0366465 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.036597 |
| DKK3 | dickkopf WNT signaling pathway inhibitor 3 | -0.0354504 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0352792 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0347881 |
| S100A10 | S100 calcium binding protein A10 | -0.0343999 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0339526 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0334506 |
| SOX9 | SRY (sex determining region Y)-box 9 | -0.0334354 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | -0.0331706 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0326791 |
| SPAG9 | sperm associated antigen 9 | -0.0324672 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0313703 |
| HLA-B | major histocompatibility complex, class I, B | -0.0303903 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0302079 |
| COL4A2 | collagen, type IV, alpha 2 | -0.0299292 |
| OASL | 2'-5'-oligoadenylate synthetase-like | -0.0296085 |
| TAGLN2 | transgelin 2 | -0.0295595 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0289782 |
| CAVIN1 | caveolae associated protein 1 | -0.028734 |
| SORBS2 | sorbin and SH3 domain containing 2 | -0.0280345 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0277693 |
| AEBP2 | AE binding protein 2 | -0.0265895 |
| JAZF1 | JAZF zinc finger 1 | -0.0265503 |
| SUCNR1 | succinate receptor 1 | -0.0264453 |
| SSBP2 | single-stranded DNA binding protein 2 | -0.0256351 |
| HLA-C | major histocompatibility complex, class I, C | -0.0254718 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0253758 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0253148 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0252017 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0250425 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0248017 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0247016 |
| LRRC17 | leucine rich repeat containing 17 | -0.0243508 |
| TNS3 | tensin 3 | -0.0241854 |
| GNAS | GNAS complex locus | -0.0241041 |
| DPYSL3 | dihydropyrimidinase-like 3 | -0.0239313 |
| COL3A1 | collagen, type III, alpha 1 | -0.0239031 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0237761 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0234999 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0233592 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0231815 |
| PCDH7 | protocadherin 7 | -0.0231245 |
| S100A4 | S100 calcium binding protein A4 | -0.0226536 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0225763 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0222772 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0222391 |
| MT1X | metallothionein 1X | -0.0222238 |
| DDR2 | discoidin domain receptor tyrosine kinase 2 | -0.0221909 |
| ACTG1 | actin gamma 1 | -0.0221194 |
| FRMD4A | FERM domain containing 4A | -0.0218718 |
| IER3 | immediate early response 3 | -0.0218048 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | -0.0217976 |
| CUX1 | cut-like homeobox 1 | -0.0216154 |
| PIAS1 | protein inhibitor of activated STAT, 1 | -0.0216025 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | -0.0215795 |
| CBX3 | chromobox homolog 3 | -0.0214932 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0214878 |
