| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Lipoic acid perturbation in A-427 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Lipoic acid_A-427 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0996791 |
| YBX3 | Y box binding protein 3 | 0.0578412 |
| AREG | amphiregulin | 0.0568786 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0474739 |
| CELF2 | CUGBP, Elav-like family member 2 | 0.0471807 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0460694 |
| PDGFC | platelet derived growth factor C | 0.0399967 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0354411 |
| DST | dystonin | 0.0348819 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0333557 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.033352 |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.0330109 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0315822 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0315416 |
| MPG | N-methylpurine-DNA glycosylase | 0.0313858 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0303661 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.027189 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0270436 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0250899 |
| YAP1 | Yes-associated protein 1 | 0.0246553 |
| MARCHF4 | membrane associated ring-CH-type finger 4 | 0.0243271 |
| SFPQ | splicing factor proline/glutamine-rich | 0.024278 |
| CLTC | clathrin, heavy chain (Hc) | 0.0239413 |
| MYPN | myopalladin | 0.0234934 |
| RPL12 | ribosomal protein L12 | 0.0234924 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0231167 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0227215 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0223105 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0222006 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0221407 |
| INTS6 | integrator complex subunit 6 | 0.0220948 |
| CANX | calnexin | 0.0220695 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0219774 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.021407 |
| RPS2 | ribosomal protein S2 | 0.0207372 |
| ZNF217 | zinc finger protein 217 | 0.0197607 |
| NEK7 | NIMA-related kinase 7 | 0.0196995 |
| HDAC9 | histone deacetylase 9 | 0.0196487 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | 0.0192684 |
| EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit | 0.0190909 |
| SETX | senataxin | 0.0189072 |
| HELLS | helicase, lymphoid-specific | 0.0185986 |
| CDK17 | cyclin-dependent kinase 17 | 0.0184475 |
| SERTAD2 | SERTA domain containing 2 | 0.0182745 |
| PCDH7 | protocadherin 7 | 0.0180119 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.017986 |
| ZNF644 | zinc finger protein 644 | 0.0177989 |
| ANKS1B | ankyrin repeat and sterile alpha motif domain containing 1B | 0.0177086 |
| ERBIN | erbb2 interacting protein | 0.0176475 |
| FBXL17 | F-box and leucine-rich repeat protein 17 | 0.017584 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0172713 |
| EDARADD | EDAR-associated death domain | 0.017064 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0168334 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0165149 |
| LARP4B | La ribonucleoprotein domain family, member 4B | 0.0165109 |
| SPAG9 | sperm associated antigen 9 | 0.0163809 |
| TJP1 | tight junction protein 1 | 0.0161417 |
| VCL | vinculin | 0.0161194 |
| CALD1 | caldesmon 1 | 0.0157875 |
| BRD4 | bromodomain containing 4 | 0.0157287 |
| MON2 | MON2 homolog (S. cerevisiae) | 0.0155359 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0152637 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0152401 |
| PDK4 | pyruvate dehydrogenase kinase, isozyme 4 | 0.0152257 |
| RTN4 | reticulon 4 | 0.0151815 |
| SON | SON DNA binding protein | 0.0151105 |
| FNIP1 | folliculin interacting protein 1 | 0.0151045 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0150829 |
| RCOR1 | REST corepressor 1 | 0.0149886 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.0149767 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0149606 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.014936 |
| TRA2B | transformer 2 beta homolog (Drosophila) | 0.0148832 |
| USP15 | ubiquitin specific peptidase 15 | 0.0148032 |
| RPS4X | ribosomal protein S4, X-linked | 0.0146489 |
| DIAPH3 | diaphanous-related formin 3 | 0.0145632 |
| RAPGEF6 | Rap guanine nucleotide exchange factor (GEF) 6 | 0.0144564 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0144155 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0142095 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | 0.0141993 |
| STK4 | serine/threonine kinase 4 | 0.0141764 |
| TNRC6C | trinucleotide repeat containing 6C | 0.0141393 |
| WWOX | WW domain containing oxidoreductase | 0.0140826 |
| RRM2 | ribonucleotide reductase M2 | 0.0139872 |
| ETNK1 | ethanolamine kinase 1 | 0.0138914 |
| RALGAPB | Ral GTPase activating protein, beta subunit (non-catalytic) | 0.01371 |
| TOP1 | topoisomerase (DNA) I | 0.0136821 |
| RAP1B | RAP1B, member of RAS oncogene family | 0.0136037 |
| NEGR1 | neuronal growth regulator 1 | 0.0135523 |
| ARPC1B | actin related protein 2/3 complex, subunit 1B, 41kDa | 0.0134797 |
| POLA1 | polymerase (DNA directed), alpha 1, catalytic subunit | 0.013478 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0134671 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.013439 |
| NRXN3 | neurexin 3 | 0.0133238 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.013319 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0130894 |
| NCAPG2 | non-SMC condensin II complex, subunit G2 | 0.0130321 |
| PLK2 | polo-like kinase 2 | 0.012931 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0129259 |
| PRIM2 | primase, DNA, polypeptide 2 (58kDa) | 0.0127804 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.150498 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0863191 |
| PTMA | prothymosin, alpha | -0.0751159 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | -0.0725739 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0632106 |
| EHBP1 | EH domain binding protein 1 | -0.0502148 |
| NLGN1 | neuroligin 1 | -0.0451646 |
| ACTG1 | actin gamma 1 | -0.0421814 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0384131 |
| ASPH | aspartate beta-hydroxylase | -0.0383394 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0355995 |
| MKI67 | marker of proliferation Ki-67 | -0.0355026 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0347747 |
| RPL35A | ribosomal protein L35a | -0.034238 |
| LDHB | lactate dehydrogenase B | -0.0300191 |
| RPS6 | ribosomal protein S6 | -0.029561 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0283625 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0277072 |
| S100A10 | S100 calcium binding protein A10 | -0.0276221 |
| USP34 | ubiquitin specific peptidase 34 | -0.0269996 |
| S100A6 | S100 calcium binding protein A6 | -0.0267414 |
| ANXA1 | annexin A1 | -0.0266353 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0258305 |
| MATR3 | matrin 3 | -0.0248076 |
| LRRTM4 | leucine rich repeat transmembrane neuronal 4 | -0.0246081 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0243252 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.022857 |
| NR5A2 | nuclear receptor subfamily 5, group A, member 2 | -0.0225355 |
| GNAS | GNAS complex locus | -0.0221306 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | -0.0217414 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0214546 |
| NHSL1 | NHS-like 1 | -0.0208769 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0206629 |
| SPATS2 | spermatogenesis associated, serine-rich 2 | -0.0206299 |
| TMSB10 | thymosin beta 10 | -0.0203103 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0202702 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | -0.0201872 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0196861 |
| RPL37A | ribosomal protein L37a | -0.0195095 |
| RPS27 | ribosomal protein S27 | -0.0194997 |
| PKM | pyruvate kinase, muscle | -0.0193647 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0192186 |
| MMP12 | matrix metallopeptidase 12 | -0.019049 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0190289 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0189851 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0188538 |
| TPM4 | tropomyosin 4 | -0.018847 |
| PGK1 | phosphoglycerate kinase 1 | -0.01884 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | -0.0187906 |
| RHOA | ras homolog family member A | -0.0187339 |
| RPS16 | ribosomal protein S16 | -0.0184867 |
| SEPTIN7 | septin 7 | -0.0183732 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | -0.0182416 |
| CUX1 | cut-like homeobox 1 | -0.0179349 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0178484 |
| RPLP1 | ribosomal protein, large, P1 | -0.0178399 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0177983 |
| BCHE | butyrylcholinesterase | -0.0176715 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.017334 |
| KIF5B | kinesin family member 5B | -0.0170703 |
| ZNF292 | zinc finger protein 292 | -0.0168206 |
| AHNAK | AHNAK nucleoprotein | -0.0163425 |
| KRR1 | KRR1, small subunit (SSU) processome component, homolog (yeast) | -0.0163368 |
| R3HDM2 | R3H domain containing 2 | -0.0162269 |
| VMP1 | vacuole membrane protein 1 | -0.0162228 |
| RPS27A | ribosomal protein S27a | -0.0160903 |
| UNC13A | unc-13 homolog A (C. elegans) | -0.0155969 |
| RPL38 | ribosomal protein L38 | -0.0155734 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | -0.0154953 |
| MTCL1 | microtubule crosslinking factor 1 | -0.0154347 |
| BRI3BP | BRI3 binding protein | -0.0154217 |
| PTPRZ1 | protein tyrosine phosphatase, receptor-type, Z polypeptide 1 | -0.0153433 |
| TMEM123 | transmembrane protein 123 | -0.015186 |
| RPL31 | ribosomal protein L31 | -0.0147645 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 | -0.0146781 |
| CDH12 | cadherin 12, type 2 (N-cadherin 2) | -0.014673 |
| LARP1 | La ribonucleoprotein domain family, member 1 | -0.0145159 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0144885 |
| RPL36A | ribosomal protein L36a | -0.0143141 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | -0.0142849 |
| PDS5A | PDS5 cohesin associated factor A | -0.0140437 |
| PCDH9 | protocadherin 9 | -0.014022 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0140123 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | -0.0139498 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0138016 |
| RPS29 | ribosomal protein S29 | -0.0137937 |
| HMGA1 | high mobility group AT-hook 1 | -0.0137356 |
| HLA-A | major histocompatibility complex, class I, A | -0.0136716 |
| DENND5B | DENN/MADD domain containing 5B | -0.0136103 |
| PRR11 | proline rich 11 | -0.0135605 |
| KSR2 | kinase suppressor of ras 2 | -0.0135136 |
| STARD4 | StAR-related lipid transfer (START) domain containing 4 | -0.0134792 |
| HMGB1 | high mobility group box 1 | -0.0134506 |
| DDIT3 | DNA-damage-inducible transcript 3 | -0.0133692 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0133444 |
| RBM25 | RNA binding motif protein 25 | -0.0133263 |
| NEBL | nebulette | -0.0132701 |
| SYT1 | synaptotagmin I | -0.0130945 |
| TSPAN5 | tetraspanin 5 | -0.0130813 |
| CCN2 | cellular communication network factor 2 | -0.0130518 |
