| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Lipoic acid perturbation in AN3 CA cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Lipoic acid_AN3 CA drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MEST | mesoderm specific transcript | 0.108894 |
| OGA | O-GlcNAcase | 0.0700653 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0660976 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0564185 |
| USP34 | ubiquitin specific peptidase 34 | 0.0562213 |
| UTRN | utrophin | 0.0548524 |
| VEGFA | vascular endothelial growth factor A | 0.0537422 |
| PHIP | pleckstrin homology domain interacting protein | 0.0535095 |
| PDE10A | phosphodiesterase 10A | 0.0516186 |
| ITGAV | integrin, alpha V | 0.05132 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | 0.0510147 |
| TSHZ2 | teashirt zinc finger homeobox 2 | 0.0505325 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0495213 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0480694 |
| MKI67 | marker of proliferation Ki-67 | 0.0449651 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0442545 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0428326 |
| CANX | calnexin | 0.0417111 |
| BCAS3 | breast carcinoma amplified sequence 3 | 0.0393052 |
| NR6A1 | nuclear receptor subfamily 6, group A, member 1 | 0.0382969 |
| CSNK1G3 | casein kinase 1, gamma 3 | 0.0380336 |
| PCM1 | pericentriolar material 1 | 0.0380208 |
| RANBP17 | RAN binding protein 17 | 0.0377406 |
| NCKAP1 | NCK-associated protein 1 | 0.03755 |
| DST | dystonin | 0.0375411 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0366179 |
| XPO1 | exportin 1 | 0.0363955 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0359716 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.035935 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0354912 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0352968 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0349293 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0346905 |
| YEATS2 | YEATS domain containing 2 | 0.0346465 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 | 0.034616 |
| TENT2 | terminal nucleotidyltransferase 2 | 0.0345304 |
| SOX6 | SRY (sex determining region Y)-box 6 | 0.0335387 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0335094 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0333784 |
| WWC2 | WW and C2 domain containing 2 | 0.0330086 |
| GSE1 | Gse1 coiled-coil protein | 0.0326889 |
| LARP4B | La ribonucleoprotein domain family, member 4B | 0.0319715 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0316657 |
| GPHN | gephyrin | 0.0315389 |
| SMCHD1 | structural maintenance of chromosomes flexible hinge domain containing 1 | 0.0314457 |
| HYOU1 | hypoxia up-regulated 1 | 0.0313792 |
| RALGAPA1 | Ral GTPase activating protein, alpha subunit 1 (catalytic) | 0.0313167 |
| MAN1A2 | mannosidase, alpha, class 1A, member 2 | 0.0312833 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0311895 |
| MED13 | mediator complex subunit 13 | 0.0308732 |
| TENT4A | terminal nucleotidyltransferase 4A | 0.0307778 |
| VPS13D | vacuolar protein sorting 13 homolog D (S. cerevisiae) | 0.0306953 |
| PRELID2 | PRELI domain containing 2 | 0.0306907 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0302455 |
| BBX | bobby sox homolog (Drosophila) | 0.0301589 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0300621 |
| ZNF516 | zinc finger protein 516 | 0.0299769 |
| BCOR | BCL6 corepressor | 0.0298017 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0294718 |
| ZNF407 | zinc finger protein 407 | 0.0293541 |
| PCDH7 | protocadherin 7 | 0.0290931 |
| MAP4 | microtubule-associated protein 4 | 0.0289928 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | 0.0289155 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | 0.0288997 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0283401 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0283172 |
| WDPCP | WD repeat containing planar cell polarity effector | 0.0281042 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0279217 |
| METTL15 | methyltransferase like 15 | 0.0278556 |
| OSBPL10 | oxysterol binding protein-like 10 | 0.0277508 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0276633 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0276251 |
| PIAS1 | protein inhibitor of activated STAT, 1 | 0.0274326 |
| TAOK1 | TAO kinase 1 | 0.0271731 |
| SRPK2 | SRSF protein kinase 2 | 0.0271674 |
| ABI2 | abl-interactor 2 | 0.027132 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0271089 |
| KIF5B | kinesin family member 5B | 0.0270929 |
| CLINT1 | clathrin interactor 1 | 0.0269917 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | 0.0268384 |
| POM121C | POM121 transmembrane nucleoporin C | 0.0265418 |
| SCD5 | stearoyl-CoA desaturase 5 | 0.0264632 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | 0.0264245 |
| BCKDHB | branched chain keto acid dehydrogenase E1, beta polypeptide | 0.0263666 |
| UBR2 | ubiquitin protein ligase E3 component n-recognin 2 | 0.0261667 |
| ZMYM4 | zinc finger, MYM-type 4 | 0.0260482 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | 0.0259857 |
| TASOR2 | transcription activation suppressor family member 2 | 0.0255748 |
| VCL | vinculin | 0.0253988 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0250479 |
| EYA1 | EYA transcriptional coactivator and phosphatase 1 | 0.025031 |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa | 0.0249947 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0249357 |
| ZNRF1 | zinc and ring finger 1, E3 ubiquitin protein ligase | 0.0248775 |
| PKP4 | plakophilin 4 | 0.0248514 |
| ATF7IP | activating transcription factor 7 interacting protein | 0.0247125 |
| NIN | ninein (GSK3B interacting protein) | 0.0246593 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0241404 |
| CLTC | clathrin, heavy chain (Hc) | 0.0240745 |
| SRSF11 | serine/arginine-rich splicing factor 11 | 0.0240023 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PRKG1 | protein kinase, cGMP-dependent, type I | -0.210335 |
| VIM | vimentin | -0.163944 |
| PEG10 | paternally expressed 10 | -0.119233 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.118595 |
| CADM2 | cell adhesion molecule 2 | -0.0890168 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | -0.0880622 |
| HMGA2 | high mobility group AT-hook 2 | -0.0782918 |
| ACTG1 | actin gamma 1 | -0.0756961 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.070463 |
| PTMA | prothymosin, alpha | -0.0619693 |
| MGP | matrix Gla protein | -0.0591808 |
| RPL37A | ribosomal protein L37a | -0.0564833 |
| NFIB | nuclear factor I/B | -0.055495 |
| IGF2R | insulin-like growth factor 2 receptor | -0.0524343 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0521543 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0507865 |
| RPL23 | ribosomal protein L23 | -0.0507827 |
| TMSB4X | thymosin beta 4, X-linked | -0.0440632 |
| RPS27A | ribosomal protein S27a | -0.0428807 |
| PGK1 | phosphoglycerate kinase 1 | -0.0416962 |
| RPS24 | ribosomal protein S24 | -0.0389566 |
| EXOC4 | exocyst complex component 4 | -0.0389297 |
| MT2A | metallothionein 2A | -0.0385906 |
| TMSB10 | thymosin beta 10 | -0.0375691 |
| RPS10 | ribosomal protein S10 | -0.0374582 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0372752 |
| FLNB | filamin B, beta | -0.0369005 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0368145 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0352005 |
| IER3 | immediate early response 3 | -0.0349517 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0346114 |
| PDGFC | platelet derived growth factor C | -0.0344889 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | -0.0342194 |
| RPS8 | ribosomal protein S8 | -0.0340597 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0337133 |
| NPR2 | natriuretic peptide receptor 2 | -0.0329651 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | -0.0326418 |
| FGFR2 | fibroblast growth factor receptor 2 | -0.0325576 |
| RFX7 | regulatory factor X, 7 | -0.0317966 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -0.0315184 |
| RHEB | Ras homolog enriched in brain | -0.0314352 |
| COTL1 | coactosin-like F-actin binding protein 1 | -0.0312964 |
| UBC | ubiquitin C | -0.0310964 |
| NFATC3 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 | -0.0307341 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0303418 |
| ATP6V1H | ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H | -0.0302217 |
| KANTR | KDM5C adjacent non-coding transcript | -0.0298891 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0298605 |
| LITAF | lipopolysaccharide-induced TNF factor | -0.0298027 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0295776 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0294671 |
| TTC28 | tetratricopeptide repeat domain 28 | -0.0293966 |
| FRMD6 | FERM domain containing 6 | -0.0289767 |
| HMGB2 | high mobility group box 2 | -0.0289489 |
| FNBP1 | formin binding protein 1 | -0.0287247 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0286433 |
| COL1A2 | collagen, type I, alpha 2 | -0.0286026 |
| MEOX2 | mesenchyme homeobox 2 | -0.028077 |
| DENND5A | DENN/MADD domain containing 5A | -0.0276942 |
| SIK3 | SIK family kinase 3 | -0.0275676 |
| CHKA | choline kinase alpha | -0.0275303 |
| CHD9 | chromodomain helicase DNA binding protein 9 | -0.0275267 |
| SERBP1 | SERPINE1 mRNA binding protein 1 | -0.0269389 |
| RPS14 | ribosomal protein S14 | -0.026518 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | -0.0262378 |
| CREBBP | CREB binding protein | -0.026225 |
| RACK1 | receptor for activated C kinase 1 | -0.026219 |
| FBXL2 | F-box and leucine-rich repeat protein 2 | -0.0256258 |
| HBP1 | HMG-box transcription factor 1 | -0.025613 |
| DDIT4 | DNA-damage-inducible transcript 4 | -0.0255866 |
| TOP1 | topoisomerase (DNA) I | -0.0255095 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | -0.0254554 |
| JAM3 | junctional adhesion molecule 3 | -0.0253746 |
| NFIA | nuclear factor I/A | -0.0250526 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.024657 |
| RNF130 | ring finger protein 130 | -0.0246518 |
| GAS2L3 | growth arrest-specific 2 like 3 | -0.0242941 |
| MTUS1 | microtubule associated tumor suppressor 1 | -0.0242835 |
| MEIS2 | Meis homeobox 2 | -0.0242267 |
| RPL35A | ribosomal protein L35a | -0.024105 |
| PRKCA | protein kinase C, alpha | -0.023844 |
| DEK | DEK proto-oncogene | -0.0237427 |
| RPL7 | ribosomal protein L7 | -0.0235731 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | -0.0235061 |
| MIB1 | mindbomb E3 ubiquitin protein ligase 1 | -0.0235036 |
| ATP5MG | ATP synthase membrane subunit g | -0.0234612 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0234439 |
| ZFAND6 | zinc finger, AN1-type domain 6 | -0.0233479 |
| SBNO1 | strawberry notch homolog 1 (Drosophila) | -0.0233149 |
| SLC16A1 | solute carrier family 16 (monocarboxylate transporter), member 1 | -0.0231393 |
| RPL31 | ribosomal protein L31 | -0.0230912 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0229986 |
| ANP32A | acidic (leucine-rich) nuclear phosphoprotein 32 family, member A | -0.0225766 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0225702 |
| EVL | Enah/Vasp-like | -0.0225175 |
| GPBP1 | GC-rich promoter binding protein 1 | -0.0224919 |
| KDM3B | lysine (K)-specific demethylase 3B | -0.0221694 |
| RPS19 | ribosomal protein S19 | -0.0219995 |
| ILRUN | inflammation and lipid regulator with UBA-like and NBR1-like domains | -0.0219728 |
| ATP8A1 | ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1 | -0.0219369 |
