| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Lipoic acid perturbation in BT-474 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Lipoic acid_BT-474 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| VMP1 | vacuole membrane protein 1 | 0.0981069 |
| NDRG1 | N-myc downstream regulated 1 | 0.0857164 |
| FBXL20 | F-box and leucine-rich repeat protein 20 | 0.0670385 |
| VEGFA | vascular endothelial growth factor A | 0.054435 |
| NCOA3 | nuclear receptor coactivator 3 | 0.0492829 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0446292 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0442055 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0437574 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0374794 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0370709 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0366775 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0356974 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0347493 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0331836 |
| INTS6 | integrator complex subunit 6 | 0.0315907 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0314867 |
| ZNF292 | zinc finger protein 292 | 0.0311589 |
| UNC13B | unc-13 homolog B (C. elegans) | 0.0305472 |
| FAM168A | family with sequence similarity 168, member A | 0.0299361 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0295197 |
| PIP4K2B | phosphatidylinositol-5-phosphate 4-kinase, type II, beta | 0.0292986 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.027901 |
| IGFBP5 | insulin-like growth factor binding protein 5 | 0.027523 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0270901 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0266948 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0265754 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.026123 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0261137 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0257298 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0256497 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.0248047 |
| RPS3 | ribosomal protein S3 | 0.0245309 |
| BRD4 | bromodomain containing 4 | 0.0244142 |
| RPL37A | ribosomal protein L37a | 0.0240021 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0236875 |
| TPD52 | tumor protein D52 | 0.0235981 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0231728 |
| PCBP2 | poly(rC) binding protein 2 | 0.0231337 |
| RTN3 | reticulon 3 | 0.0225629 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0223492 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0222858 |
| VIPR2 | vasoactive intestinal peptide receptor 2 | 0.0219818 |
| USO1 | USO1 vesicle transport factor | 0.0218527 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0218238 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0215531 |
| MMP24OS | MMP24 opposite strand | 0.0213991 |
| POTEF | POTE ankyrin domain family, member F | 0.0213373 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0207643 |
| YAP1 | Yes-associated protein 1 | 0.0206809 |
| HELZ | helicase with zinc finger | 0.0200377 |
| PKM | pyruvate kinase, muscle | 0.0200163 |
| ATP1A4 | ATPase, Na+/K+ transporting, alpha 4 polypeptide | 0.0199589 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0199236 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0198293 |
| TPM3 | tropomyosin 3 | 0.019783 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0197666 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0195227 |
| RUNX1 | runt-related transcription factor 1 | 0.0195179 |
| MCL1 | myeloid cell leukemia 1 | 0.0194689 |
| CCNL1 | cyclin L1 | 0.0194644 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0192375 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0190889 |
| FGD4 | FYVE, RhoGEF and PH domain containing 4 | 0.0190069 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0187952 |
| RCOR1 | REST corepressor 1 | 0.0186963 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0185545 |
| AHCTF1 | AT hook containing transcription factor 1 | 0.0184635 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0183909 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0182719 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0182493 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | 0.0182304 |
| LARP1B | La ribonucleoprotein domain family, member 1B | 0.0180267 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0179457 |
| DENND5A | DENN/MADD domain containing 5A | 0.017895 |
| CMIP | c-Maf inducing protein | 0.0177601 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0177557 |
| SCFD1 | sec1 family domain containing 1 | 0.017725 |
| LCOR | ligand dependent nuclear receptor corepressor | 0.0177209 |
| SLC22A23 | solute carrier family 22, member 23 | 0.0177093 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0176569 |
| TAB3 | TGF-beta activated kinase 1/MAP3K7 binding protein 3 | 0.0175986 |
| PLEKHG4B | pleckstrin homology domain containing, family G (with RhoGef domain) member 4B | 0.0174632 |
| GATAD2B | GATA zinc finger domain containing 2B | 0.0174488 |
| KRT86 | keratin 86, type II | 0.0174474 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.0172901 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0171946 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.0171693 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0169722 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0169135 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0166928 |
| PCGF2 | polycomb group ring finger 2 | 0.0166396 |
| WASF2 | WAS protein family, member 2 | 0.0166265 |
| SETD5 | SET domain containing 5 | 0.016589 |
| SBF2 | SET binding factor 2 | 0.0164931 |
| LDHA | lactate dehydrogenase A | 0.0163462 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | 0.0160919 |
| TOB1 | transducer of ERBB2, 1 | 0.0159849 |
| SPAG9 | sperm associated antigen 9 | 0.0159745 |
| SEC16A | SEC16 homolog A (S. cerevisiae) | 0.0158263 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0157011 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ACACA | acetyl-CoA carboxylase alpha | -0.139402 |
| CATSPERB | catsper channel auxiliary subunit beta | -0.1218 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.109993 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0764402 |
| ASPH | aspartate beta-hydroxylase | -0.0745544 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0660551 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0646236 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.060746 |
| RARRES1 | retinoic acid receptor responder (tazarotene induced) 1 | -0.0579524 |
| OSMR | oncostatin M receptor | -0.0562474 |
| CDK12 | cyclin-dependent kinase 12 | -0.0550312 |
| CCND1 | cyclin D1 | -0.0507346 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | -0.0490607 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0472049 |
| IL1RAPL2 | interleukin 1 receptor accessory protein-like 2 | -0.0464675 |
| RPL19 | ribosomal protein L19 | -0.0451002 |
| TMSB4X | thymosin beta 4, X-linked | -0.0425391 |
| AHNAK | AHNAK nucleoprotein | -0.0388021 |
| PBX1 | pre-B-cell leukemia homeobox 1 | -0.037484 |
| MT2A | metallothionein 2A | -0.0373031 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | -0.0348593 |
| S100A9 | S100 calcium binding protein A9 | -0.0348253 |
| S100A8 | S100 calcium binding protein A8 | -0.0342375 |
| DNAH14 | dynein, axonemal, heavy chain 14 | -0.0337768 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0331087 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0324541 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.032394 |
| TC2N | tandem C2 domains, nuclear | -0.0313221 |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) | -0.0309024 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0308593 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0308326 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0307418 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.030595 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | -0.0300222 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0299929 |
| ZNF217 | zinc finger protein 217 | -0.0294037 |
| TMSB10 | thymosin beta 10 | -0.0290055 |
| TTC6 | tetratricopeptide repeat domain 6 | -0.0284011 |
| BCAS1 | breast carcinoma amplified sequence 1 | -0.0281326 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0277116 |
| PGK1 | phosphoglycerate kinase 1 | -0.0276741 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0270668 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | -0.0269441 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.026713 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0266857 |
| PLSCR1 | phospholipid scramblase 1 | -0.0264877 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.026432 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0263767 |
| TENM2 | teneurin transmembrane protein 2 | -0.0263745 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0262284 |
| GDPD1 | glycerophosphodiester phosphodiesterase domain containing 1 | -0.0256162 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0250669 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | -0.0250292 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0249789 |
| SERPINB4 | serpin peptidase inhibitor, clade B (ovalbumin), member 4 | -0.0249091 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0248331 |
| SYTL2 | synaptotagmin-like 2 | -0.0246461 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | -0.0243919 |
| FOXP1 | forkhead box P1 | -0.0243901 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0234289 |
| MYO1D | myosin ID | -0.023408 |
| SERPINB3 | serpin peptidase inhibitor, clade B (ovalbumin), member 3 | -0.0233676 |
| NRG3 | neuregulin 3 | -0.023279 |
| ACSS2 | acyl-CoA synthetase short-chain family member 2 | -0.0232122 |
| TNS3 | tensin 3 | -0.0231376 |
| TMC5 | transmembrane channel-like 5 | -0.0228522 |
| GSK3B | glycogen synthase kinase 3 beta | -0.0226916 |
| SMIM14 | small integral membrane protein 14 | -0.0225135 |
| CD164 | CD164 molecule, sialomucin | -0.0225103 |
| DTNA | dystrobrevin, alpha | -0.0222012 |
| RPL35A | ribosomal protein L35a | -0.0220562 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0220057 |
| GNAS | GNAS complex locus | -0.0219935 |
| GLCCI1 | glucocorticoid induced 1 | -0.0214043 |
| CEP250 | centrosomal protein 250kDa | -0.0212919 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0211894 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0210545 |
| ANKLE2 | ankyrin repeat and LEM domain containing 2 | -0.021037 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0206222 |
| KRT7 | keratin 7, type II | -0.0205116 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0205008 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | -0.0204561 |
| RESF1 | retroelement silencing factor 1 | -0.0204109 |
| S100A6 | S100 calcium binding protein A6 | -0.0203833 |
| LGALS12 | lectin, galactoside-binding, soluble, 12 | -0.0201095 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0199997 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0198426 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0197524 |
| TENM4 | teneurin transmembrane protein 4 | -0.0195632 |
| AUTS2 | autism susceptibility candidate 2 | -0.0191549 |
| ARHGAP29 | Rho GTPase activating protein 29 | -0.0191413 |
| ZFAND6 | zinc finger, AN1-type domain 6 | -0.0191127 |
| PSMD3 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 3 | -0.0187609 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0187279 |
| DSG2 | desmoglein 2 | -0.0187267 |
| FDPS | farnesyl diphosphate synthase | -0.0186369 |
| CDH15 | cadherin 15, type 1, M-cadherin (myotubule) | -0.0185639 |
| TNNC1 | troponin C type 1 (slow) | -0.0184996 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0180396 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0179854 |
