| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Lipoic acid perturbation in C32 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Lipoic acid_C32 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.10891 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.101594 |
| FN1 | fibronectin 1 | 0.0727151 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0661745 |
| TMEM178B | transmembrane protein 178B | 0.0608013 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0572722 |
| PRELID2 | PRELI domain containing 2 | 0.0543468 |
| MDGA2 | MAM domain containing glycosylphosphatidylinositol anchor 2 | 0.0523862 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0468137 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0415418 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0399381 |
| LEF1 | lymphoid enhancer-binding factor 1 | 0.0341616 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0325983 |
| TLE4 | transducin-like enhancer of split 4 | 0.0300851 |
| PPFIA4 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4 | 0.0298497 |
| PHC2 | polyhomeotic homolog 2 (Drosophila) | 0.0292073 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0284966 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0265352 |
| SETBP1 | SET binding protein 1 | 0.0262886 |
| COPA | coatomer protein complex, subunit alpha | 0.025472 |
| COG5 | component of oligomeric golgi complex 5 | 0.0253239 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0237012 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0236788 |
| NBAS | neuroblastoma amplified sequence | 0.0231668 |
| ATXN1 | ataxin 1 | 0.0231309 |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) | 0.0217035 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0210209 |
| PTCHD4 | patched domain containing 4 | 0.0201832 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | 0.0200558 |
| EXOC4 | exocyst complex component 4 | 0.019868 |
| UTRN | utrophin | 0.0180401 |
| USP53 | ubiquitin specific peptidase 53 | 0.0180035 |
| FAM3C | family with sequence similarity 3, member C | 0.0179845 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0177753 |
| UBN2 | ubinuclein 2 | 0.0177647 |
| TRIM9 | tripartite motif containing 9 | 0.0177254 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0175856 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0173348 |
| FLNB | filamin B, beta | 0.0168841 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0167093 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.0166809 |
| RNASE12 | ribonuclease, RNase A family, 12 (non-active) | 0.0166489 |
| HYOU1 | hypoxia up-regulated 1 | 0.0164961 |
| VMP1 | vacuole membrane protein 1 | 0.0164347 |
| SETX | senataxin | 0.016121 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.016077 |
| ANK2 | ankyrin 2, neuronal | 0.0157925 |
| INTS6 | integrator complex subunit 6 | 0.0157825 |
| EFCAB13 | EF-hand calcium binding domain 13 | 0.015695 |
| COG6 | component of oligomeric golgi complex 6 | 0.015323 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.0152768 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0151864 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0151699 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0151596 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.0151263 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0151175 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.0151064 |
| SEC24D | SEC24 family member D | 0.0150268 |
| DST | dystonin | 0.0149568 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0146831 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0146077 |
| MTERF1 | mitochondrial transcription termination factor 1 | 0.0143325 |
| CALR | calreticulin | 0.0142725 |
| IFRD1 | interferon-related developmental regulator 1 | 0.0142321 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0142257 |
| PTK2 | protein tyrosine kinase 2 | 0.0141761 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0141329 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0141091 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0140562 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0140383 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0137688 |
| CADM1 | cell adhesion molecule 1 | 0.013679 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0136035 |
| GOLGB1 | golgin B1 | 0.0135273 |
| SLC9A1 | solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 | 0.0134536 |
| SOX13 | SRY (sex determining region Y)-box 13 | 0.0133095 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0132861 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0130955 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | 0.0130468 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0130134 |
| ARHGEF2 | Rho/Rac guanine nucleotide exchange factor (GEF) 2 | 0.0129408 |
| ACTN1 | actinin, alpha 1 | 0.0128918 |
| PAX3 | paired box 3 | 0.0127001 |
| SEM1 | SEM1 26S proteasome subunit | 0.0126895 |
| ZFYVE28 | zinc finger, FYVE domain containing 28 | 0.0126006 |
| OSBPL10 | oxysterol binding protein-like 10 | 0.0125239 |
| ANO6 | anoctamin 6 | 0.0124548 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0123705 |
| CTBP2 | C-terminal binding protein 2 | 0.0122318 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0121853 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.012021 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0119562 |
| LRMDA | leucine rich melanocyte differentiation associated | 0.0119156 |
| PACSIN2 | protein kinase C and casein kinase substrate in neurons 2 | 0.0119083 |
| KHDRBS3 | KH domain containing, RNA binding, signal transduction associated 3 | 0.0118749 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0115827 |
| SLIT2 | slit homolog 2 (Drosophila) | 0.0115433 |
| BTBD9 | BTB (POZ) domain containing 9 | 0.0115164 |
| TRAPPC9 | trafficking protein particle complex 9 | 0.0115163 |
| ATP2A2 | ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 | 0.0114875 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.236401 |
| VIM | vimentin | -0.14321 |
| VGF | VGF nerve growth factor inducible | -0.096534 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.081287 |
| FRMD4A | FERM domain containing 4A | -0.0757347 |
| DCT | dopachrome tautomerase | -0.0686108 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0658137 |
| ENO1 | enolase 1, (alpha) | -0.0576815 |
| HLA-B | major histocompatibility complex, class I, B | -0.0567464 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0557835 |
| S100A6 | S100 calcium binding protein A6 | -0.0555065 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0545819 |
| ACTG1 | actin gamma 1 | -0.054118 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0531195 |
| CENPF | centromere protein F, 350/400kDa | -0.0518144 |
| TMSB10 | thymosin beta 10 | -0.0517587 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0499315 |
| PGK1 | phosphoglycerate kinase 1 | -0.0488348 |
| GPC6 | glypican 6 | -0.0465654 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0446686 |
| MT2A | metallothionein 2A | -0.0421578 |
| PTMA | prothymosin, alpha | -0.0401028 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | -0.0397072 |
| CALD1 | caldesmon 1 | -0.0368173 |
| RUNX1 | runt-related transcription factor 1 | -0.0354127 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0320617 |
| CD109 | CD109 molecule | -0.0320416 |
| HMCN1 | hemicentin 1 | -0.0318504 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0314952 |
| COL19A1 | collagen, type XIX, alpha 1 | -0.0307291 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0304149 |
| NAV3 | neuron navigator 3 | -0.0298923 |
| NDRG1 | N-myc downstream regulated 1 | -0.0291767 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0281082 |
| TPI1 | triosephosphate isomerase 1 | -0.027889 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0277917 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0274672 |
| IER3 | immediate early response 3 | -0.0274236 |
| NPC1 | Niemann-Pick disease, type C1 | -0.0272859 |
| TMEM123 | transmembrane protein 123 | -0.0268705 |
| POTEF | POTE ankyrin domain family, member F | -0.0268191 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0268105 |
| RPLP1 | ribosomal protein, large, P1 | -0.0263069 |
| WDR45B | WD repeat domain 45B | -0.0255165 |
| GNAS | GNAS complex locus | -0.0254562 |
| RPS8 | ribosomal protein S8 | -0.0250017 |
| TAGLN2 | transgelin 2 | -0.0244789 |
| CD74 | CD74 molecule, major histocompatibility complex, class II invariant chain | -0.0243151 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0240512 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0233147 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0230147 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0227723 |
| CHSY1 | chondroitin sulfate synthase 1 | -0.0225366 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0224071 |
| RPL35A | ribosomal protein L35a | -0.0220606 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0220125 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0215689 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0213799 |
| PKM | pyruvate kinase, muscle | -0.0213556 |
| BACE2 | beta-site APP-cleaving enzyme 2 | -0.0210153 |
| SCFD2 | sec1 family domain containing 2 | -0.0207567 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0206895 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0203973 |
| ADM | adrenomedullin | -0.0203666 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0201859 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.020172 |
| LAMB1 | laminin, beta 1 | -0.0201322 |
| FMN1 | formin 1 | -0.0199179 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0198582 |
| TNFRSF19 | tumor necrosis factor receptor superfamily, member 19 | -0.0197163 |
| GDF15 | growth differentiation factor 15 | -0.0196552 |
| S100A9 | S100 calcium binding protein A9 | -0.0195385 |
| DDIT4 | DNA-damage-inducible transcript 4 | -0.0193098 |
| EHBP1 | EH domain binding protein 1 | -0.0190555 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0190041 |
| B2M | beta-2-microglobulin | -0.0189657 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0189028 |
| RPL37A | ribosomal protein L37a | -0.0188317 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0187415 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0186786 |
| S100A10 | S100 calcium binding protein A10 | -0.0184839 |
| MTPN | myotrophin | -0.0183113 |
| RPS12 | ribosomal protein S12 | -0.0182935 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0182612 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0180084 |
| FAM162A | family with sequence similarity 162, member A | -0.0179784 |
| A2M | alpha-2-macroglobulin | -0.0179723 |
| CD63 | CD63 molecule | -0.0177771 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0176796 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | -0.0173723 |
| RPL11 | ribosomal protein L11 | -0.0173418 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0172849 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0172835 |
| MMP14 | matrix metallopeptidase 14 (membrane-inserted) | -0.0169646 |
| OSMR | oncostatin M receptor | -0.0169076 |
| PLIN2 | perilipin 2 | -0.0169051 |
| RPL34 | ribosomal protein L34 | -0.0168974 |
| RPLP0 | ribosomal protein, large, P0 | -0.0167716 |
| ICAM1 | intercellular adhesion molecule 1 | -0.0167454 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0166486 |
