| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Lipoic acid perturbation in CFPAC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Lipoic acid_CFPAC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.161656 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.100716 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0670103 |
| DTNA | dystrobrevin, alpha | 0.0533855 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0437335 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.042725 |
| ANKRD11 | ankyrin repeat domain 11 | 0.039122 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | 0.0340427 |
| STC2 | stanniocalcin 2 | 0.0335288 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | 0.0327023 |
| RIMKLB | ribosomal modification protein rimK-like family member B | 0.0324247 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0323552 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.0313124 |
| VEGFA | vascular endothelial growth factor A | 0.0312604 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0294972 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.02854 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0279586 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0270061 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0268921 |
| ADAM28 | ADAM metallopeptidase domain 28 | 0.0261764 |
| RBCK1 | RanBP-type and C3HC4-type zinc finger containing 1 | 0.0258825 |
| LAMB3 | laminin, beta 3 | 0.0252494 |
| TGM2 | transglutaminase 2 | 0.0239601 |
| RAD51B | RAD51 paralog B | 0.0235138 |
| SGMS2 | sphingomyelin synthase 2 | 0.0225826 |
| GOLGB1 | golgin B1 | 0.0218002 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0215671 |
| OPTN | optineurin | 0.020694 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | 0.0206622 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0203617 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0200237 |
| SRP54 | signal recognition particle 54kDa | 0.0197654 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0197492 |
| NDRG1 | N-myc downstream regulated 1 | 0.019317 |
| HM13 | histocompatibility (minor) 13 | 0.0191884 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | 0.0183498 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0182496 |
| TINAGL1 | tubulointerstitial nephritis antigen-like 1 | 0.0172034 |
| KIAA1217 | KIAA1217 | 0.0171938 |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) | 0.0171773 |
| EPAS1 | endothelial PAS domain protein 1 | 0.017136 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | 0.0165366 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | 0.0164356 |
| TNFRSF6B | tumor necrosis factor receptor superfamily, member 6b, decoy | 0.0162216 |
| LCN2 | lipocalin 2 | 0.0157882 |
| BAG6 | BCL2-associated athanogene 6 | 0.0155206 |
| FAT1 | FAT atypical cadherin 1 | 0.015366 |
| NRG1 | neuregulin 1 | 0.0152628 |
| SEC24D | SEC24 family member D | 0.0151869 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | 0.0150555 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0149755 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0149709 |
| LAMA5 | laminin, alpha 5 | 0.0145827 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | 0.0144025 |
| PER2 | period circadian clock 2 | 0.0141962 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0141319 |
| CMIP | c-Maf inducing protein | 0.0140942 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | 0.0140125 |
| NAV2 | neuron navigator 2 | 0.0138288 |
| RNF149 | ring finger protein 149 | 0.013696 |
| PPP2R2C | protein phosphatase 2, regulatory subunit B, gamma | 0.0135346 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0134741 |
| ANXA1 | annexin A1 | 0.0132468 |
| COPA | coatomer protein complex, subunit alpha | 0.0132298 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0132163 |
| CD68 | CD68 molecule | 0.013171 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.0130631 |
| MCL1 | myeloid cell leukemia 1 | 0.0129466 |
| ZFYVE28 | zinc finger, FYVE domain containing 28 | 0.0128688 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | 0.0127364 |
| LRRC49 | leucine rich repeat containing 49 | 0.0126609 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | 0.0126361 |
| NGLY1 | N-glycanase 1 | 0.012494 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0124933 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0124774 |
| CLDN4 | claudin 4 | 0.0124499 |
| ZNF185 | zinc finger protein 185 (LIM domain) | 0.0124006 |
| STT3A | STT3A, subunit of the oligosaccharyltransferase complex (catalytic) | 0.0123308 |
| RARA | retinoic acid receptor, alpha | 0.0122291 |
| HIP1 | huntingtin interacting protein 1 | 0.0121323 |
| LOXL2 | lysyl oxidase-like 2 | 0.0118867 |
| ATP2C2 | ATPase, Ca++ transporting, type 2C, member 2 | 0.0118689 |
| C3 | complement component 3 | 0.0117847 |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 | 0.0117768 |
| ANO10 | anoctamin 10 | 0.0117603 |
| EIF2AK3 | eukaryotic translation initiation factor 2-alpha kinase 3 | 0.0116295 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0116167 |
| FRY | furry homolog (Drosophila) | 0.0116058 |
| ZNRF1 | zinc and ring finger 1, E3 ubiquitin protein ligase | 0.0114084 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0112864 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.0112417 |
| C1D | C1D nuclear receptor corepressor | 0.0110404 |
| KIRREL1 | kirre like nephrin family adhesion molecule 1 | 0.0109793 |
| PGM3 | phosphoglucomutase 3 | 0.0109248 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | 0.0109064 |
| HKDC1 | hexokinase domain containing 1 | 0.0108892 |
| KIAA1671 | KIAA1671 | 0.0108549 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | 0.0107957 |
| SLC2A13 | solute carrier family 2 (facilitated glucose transporter), member 13 | 0.0107227 |
| CFB | complement factor B | 0.010709 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | -0.191597 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.185959 |
| PTMA | prothymosin, alpha | -0.16082 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.133073 |
| TMSB4X | thymosin beta 4, X-linked | -0.106878 |
| MMP7 | matrix metallopeptidase 7 | -0.106146 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.103591 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.100812 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0889142 |
| LAMC2 | laminin, gamma 2 | -0.0861256 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0850885 |
| B2M | beta-2-microglobulin | -0.0846192 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.0822227 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0770676 |
| RPL19 | ribosomal protein L19 | -0.0734952 |
| CD2AP | CD2-associated protein | -0.0731223 |
| PGK1 | phosphoglycerate kinase 1 | -0.0712862 |
| ASPH | aspartate beta-hydroxylase | -0.070428 |
| TMSB10 | thymosin beta 10 | -0.0694216 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0684221 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0681155 |
| VCL | vinculin | -0.0678084 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0661397 |
| HLA-B | major histocompatibility complex, class I, B | -0.0658823 |
| MT1X | metallothionein 1X | -0.0657385 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.0650789 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0646062 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.060438 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0599531 |
| DST | dystonin | -0.0599154 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0588428 |
| AHNAK | AHNAK nucleoprotein | -0.0580413 |
| ACTG1 | actin gamma 1 | -0.0577622 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0566721 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0566159 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0563399 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0552729 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0544143 |
| UBC | ubiquitin C | -0.0535958 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.053335 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0531022 |
| RPL23 | ribosomal protein L23 | -0.052888 |
| APP | amyloid beta (A4) precursor protein | -0.0526281 |
| RPS2 | ribosomal protein S2 | -0.0514779 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.050808 |
| PLAU | plasminogen activator, urokinase | -0.0504695 |
| RPS8 | ribosomal protein S8 | -0.0501866 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0501129 |
| RPS6 | ribosomal protein S6 | -0.0498681 |
| EHBP1 | EH domain binding protein 1 | -0.0493658 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0492434 |
| PLAUR | plasminogen activator, urokinase receptor | -0.0484323 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0480965 |
| TPM1 | tropomyosin 1 (alpha) | -0.0475098 |
| RPS24 | ribosomal protein S24 | -0.0470113 |
| RPS3 | ribosomal protein S3 | -0.0467074 |
| RTN4 | reticulon 4 | -0.0459668 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0456794 |
| RPL11 | ribosomal protein L11 | -0.0451508 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0441403 |
| DSG2 | desmoglein 2 | -0.0436442 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | -0.0435386 |
| MYOF | myoferlin | -0.0432988 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.042432 |
| ANXA2 | annexin A2 | -0.0413601 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0413546 |
| EPCAM | epithelial cell adhesion molecule | -0.0410228 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0410072 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0409071 |
| ITPRID2 | ITPR interacting domain containing 2 | -0.0404529 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.040043 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0398647 |
| MACC1 | metastasis associated in colon cancer 1 | -0.0397646 |
| RPLP1 | ribosomal protein, large, P1 | -0.0390963 |
| ITGA6 | integrin, alpha 6 | -0.0388107 |
| POTEF | POTE ankyrin domain family, member F | -0.0385186 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0383709 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0380785 |
| RPS21 | ribosomal protein S21 | -0.0380198 |
| RPS12 | ribosomal protein S12 | -0.0379502 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0376487 |
| IER3 | immediate early response 3 | -0.0371357 |
| VIM | vimentin | -0.0371276 |
| LAMA4 | laminin, alpha 4 | -0.0369196 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0367332 |
| LAMB1 | laminin, beta 1 | -0.0366671 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0359296 |
| PCDH7 | protocadherin 7 | -0.0354956 |
| EREG | epiregulin | -0.0353763 |
| RPS29 | ribosomal protein S29 | -0.0353361 |
| RPL9 | ribosomal protein L9 | -0.035078 |
| RPL37A | ribosomal protein L37a | -0.03483 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0345519 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0341587 |
| MKI67 | marker of proliferation Ki-67 | -0.034136 |
| ACTN4 | actinin, alpha 4 | -0.0340988 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.033856 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0338278 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0338219 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0336227 |
