| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Lipoic acid perturbation in CHP-212 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Lipoic acid_CHP-212 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| VCL | vinculin | 0.122579 |
| LSAMP | limbic system-associated membrane protein | 0.0744158 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0659391 |
| TLE4 | transducin-like enhancer of split 4 | 0.0566826 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0544489 |
| NRG1 | neuregulin 1 | 0.0543874 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0476102 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0409159 |
| PRKCA | protein kinase C, alpha | 0.040119 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | 0.038661 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0377879 |
| SLIT2 | slit homolog 2 (Drosophila) | 0.0329687 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0319915 |
| RAD51B | RAD51 paralog B | 0.0303948 |
| TPM1 | tropomyosin 1 (alpha) | 0.030085 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0292359 |
| SMYD3 | SET and MYND domain containing 3 | 0.0285583 |
| MAPK10 | mitogen-activated protein kinase 10 | 0.0281133 |
| GOLGB1 | golgin B1 | 0.0275579 |
| PTPN13 | protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) | 0.0269518 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.0267732 |
| USP34 | ubiquitin specific peptidase 34 | 0.0264458 |
| EXOC4 | exocyst complex component 4 | 0.0264399 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0259741 |
| ADGRB3 | adhesion G protein-coupled receptor B3 | 0.0257346 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | 0.0255555 |
| MYO1E | myosin IE | 0.0255247 |
| VMP1 | vacuole membrane protein 1 | 0.0242774 |
| LPIN1 | lipin 1 | 0.0239348 |
| FERMT2 | fermitin family member 2 | 0.0232329 |
| GPATCH2L | G patch domain containing 2-like | 0.0227045 |
| MYO9A | myosin IXA | 0.0226871 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0224512 |
| PDE10A | phosphodiesterase 10A | 0.022388 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0221165 |
| GPATCH8 | G patch domain containing 8 | 0.0219922 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | 0.0219032 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0218216 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.0211319 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0210756 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0210216 |
| GREM2 | gremlin 2, DAN family BMP antagonist | 0.0209296 |
| RIGI | RNA sensor RIG-I | 0.0208717 |
| DNM3 | dynamin 3 | 0.0205986 |
| ZNF638 | zinc finger protein 638 | 0.0205713 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0204236 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0198002 |
| HMGA2 | high mobility group AT-hook 2 | 0.0194715 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0193856 |
| SETBP1 | SET binding protein 1 | 0.0190109 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0186492 |
| FAM107B | family with sequence similarity 107, member B | 0.0186092 |
| DACH2 | dachshund family transcription factor 2 | 0.0185592 |
| STXBP4 | syntaxin binding protein 4 | 0.0185484 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0185162 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.018307 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | 0.0183065 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0182522 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0177768 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0177432 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.017667 |
| STK38L | serine/threonine kinase 38 like | 0.0176495 |
| RUNX1T1 | runt-related transcription factor 1; translocated to, 1 (cyclin D-related) | 0.0175467 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0175069 |
| PALLD | palladin, cytoskeletal associated protein | 0.0174902 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0174782 |
| KCNT2 | potassium channel, sodium activated subfamily T, member 2 | 0.0174075 |
| MRTFA | myocardin related transcription factor A | 0.0173488 |
| FN1 | fibronectin 1 | 0.0172458 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0171165 |
| ASPH | aspartate beta-hydroxylase | 0.0171163 |
| FMN1 | formin 1 | 0.0168765 |
| PDE8A | phosphodiesterase 8A | 0.0167523 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0167512 |
| IARS1 | isoleucyl-tRNA synthetase 1 | 0.0167151 |
| CENPF | centromere protein F, 350/400kDa | 0.0166235 |
| KDM5B | lysine (K)-specific demethylase 5B | 0.0163881 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.0163452 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0162169 |
| FRMD4A | FERM domain containing 4A | 0.0161553 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0160786 |
| SNX14 | sorting nexin 14 | 0.0159557 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | 0.0158072 |
| TPR | translocated promoter region, nuclear basket protein | 0.0157833 |
| DYNC2H1 | dynein, cytoplasmic 2, heavy chain 1 | 0.0157399 |
| ZNF644 | zinc finger protein 644 | 0.0157389 |
| GYS1 | glycogen synthase 1 (muscle) | 0.0157093 |
| BCAS3 | breast carcinoma amplified sequence 3 | 0.0155605 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0155297 |
| SAMD5 | sterile alpha motif domain containing 5 | 0.0154974 |
| TBL1X | transducin (beta)-like 1X-linked | 0.0154726 |
| UBAP2L | ubiquitin associated protein 2-like | 0.0153612 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | 0.0153448 |
| LIMA1 | LIM domain and actin binding 1 | 0.0153376 |
| RFX3 | regulatory factor X, 3 (influences HLA class II expression) | 0.0152173 |
| KLHL13 | kelch-like family member 13 | 0.0151044 |
| DST | dystonin | 0.0151032 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | 0.0150911 |
| MCL1 | myeloid cell leukemia 1 | 0.0149808 |
| EFNA5 | ephrin-A5 | 0.0148725 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.205035 |
| IGF2 | insulin-like growth factor 2 | -0.098008 |
| PTMA | prothymosin, alpha | -0.0892233 |
| VIM | vimentin | -0.0836373 |
| RPL19 | ribosomal protein L19 | -0.0658081 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0584908 |
| RPS6 | ribosomal protein S6 | -0.058055 |
| RPLP1 | ribosomal protein, large, P1 | -0.0547404 |
| RPL23 | ribosomal protein L23 | -0.0540042 |
| RPL34 | ribosomal protein L34 | -0.0517353 |
| MAP1B | microtubule-associated protein 1B | -0.0502434 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0498934 |
| COL1A1 | collagen, type I, alpha 1 | -0.0482288 |
| RPS24 | ribosomal protein S24 | -0.0479691 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0479356 |
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | -0.0479118 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0445009 |
| COL3A1 | collagen, type III, alpha 1 | -0.0443956 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0442092 |
| B2M | beta-2-microglobulin | -0.0423715 |
| RPL35A | ribosomal protein L35a | -0.0388274 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0384984 |
| CSDE1 | cold shock domain containing E1, RNA-binding | -0.0374006 |
| RPL31 | ribosomal protein L31 | -0.0367228 |
| RPL27 | ribosomal protein L27 | -0.0360716 |
| GPBP1 | GC-rich promoter binding protein 1 | -0.035781 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0352245 |
| FAM13A | family with sequence similarity 13, member A | -0.0341772 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0333059 |
| MAP3K1 | mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase | -0.0329019 |
| PLAT | plasminogen activator, tissue | -0.0323899 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.0321186 |
| FNBP1 | formin binding protein 1 | -0.0319691 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0305318 |
| RPLP0 | ribosomal protein, large, P0 | -0.0303273 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0302588 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0300476 |
| RPL38 | ribosomal protein L38 | -0.0292426 |
| HELZ | helicase with zinc finger | -0.0286131 |
| GNAS | GNAS complex locus | -0.0284122 |
| RPL36 | ribosomal protein L36 | -0.027826 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0277449 |
| HAND2 | heart and neural crest derivatives expressed 2 | -0.0273559 |
| PKM | pyruvate kinase, muscle | -0.0271926 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0271203 |
| RPL32 | ribosomal protein L32 | -0.0270188 |
| RACK1 | receptor for activated C kinase 1 | -0.0269182 |
| FTL | ferritin, light polypeptide | -0.0269091 |
| S100A9 | S100 calcium binding protein A9 | -0.0268828 |
| RPS19 | ribosomal protein S19 | -0.0266869 |
| RPL8 | ribosomal protein L8 | -0.0266433 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0260508 |
| H3-3B | H3.3 histone B | -0.0257676 |
| RNF145 | ring finger protein 145 | -0.0255994 |
| RPS3 | ribosomal protein S3 | -0.0253231 |
| COL4A2 | collagen, type IV, alpha 2 | -0.0253165 |
| DCAF7 | DDB1 and CUL4 associated factor 7 | -0.0250599 |
| RPL37 | ribosomal protein L37 | -0.0243622 |
| QKI | QKI, KH domain containing, RNA binding | -0.0242086 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0238847 |
| RPS12 | ribosomal protein S12 | -0.0236364 |
| C1ORF21 | chromosome 1 open reading frame 21 | -0.0234475 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0232094 |
| TUBB | tubulin, beta class I | -0.0232001 |
| WDR45B | WD repeat domain 45B | -0.0226275 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0224786 |
| RPL7A | ribosomal protein L7a | -0.0224491 |
| RPS11 | ribosomal protein S11 | -0.0224191 |
| RPS14 | ribosomal protein S14 | -0.0223753 |
| RPS5 | ribosomal protein S5 | -0.0222865 |
| RPL12 | ribosomal protein L12 | -0.0212535 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0210917 |
| RNF213 | ring finger protein 213 | -0.0210605 |
| RPL37A | ribosomal protein L37a | -0.0210475 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0207885 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0207817 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0206931 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0206913 |
| MEIS2 | Meis homeobox 2 | -0.0206497 |
| RPS27 | ribosomal protein S27 | -0.0205603 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0204861 |
| FKBP10 | FK506 binding protein 10, 65 kDa | -0.0203952 |
| RPS8 | ribosomal protein S8 | -0.0202813 |
| NUP58 | nucleoporin 58 | -0.020136 |
| ITPRID2 | ITPR interacting domain containing 2 | -0.0200899 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0200603 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0200561 |
| RPL36A | ribosomal protein L36a | -0.0198545 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.0197483 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0196517 |
| AHNAK | AHNAK nucleoprotein | -0.0196188 |
| SPAG9 | sperm associated antigen 9 | -0.0193374 |
| RPLP2 | ribosomal protein, large, P2 | -0.0193364 |
| PTK2 | protein tyrosine kinase 2 | -0.0191962 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.019151 |
| PGK1 | phosphoglycerate kinase 1 | -0.0190674 |
| AOPEP | aminopeptidase O (putative) | -0.0190117 |
| NOP58 | NOP58 ribonucleoprotein | -0.0190007 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | -0.0189725 |
| XPR1 | xenotropic and polytropic retrovirus receptor 1 | -0.0188225 |
