| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Lipoic acid perturbation in COLO 205 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Lipoic acid_COLO 205 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LMO7 | LIM domain 7 | 0.135719 |
| STS | steroid sulfatase (microsomal), isozyme S | 0.063886 |
| PHF3 | PHD finger protein 3 | 0.0629035 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | 0.0625568 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0536523 |
| MYO1E | myosin IE | 0.0512287 |
| TMC5 | transmembrane channel-like 5 | 0.0510509 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.050113 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.046893 |
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | 0.0457653 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0370972 |
| SEPTIN9 | septin 9 | 0.0364298 |
| VMP1 | vacuole membrane protein 1 | 0.0363526 |
| MX1 | MX dynamin-like GTPase 1 | 0.036122 |
| ANXA2 | annexin A2 | 0.0357442 |
| MACC1 | metastasis associated in colon cancer 1 | 0.0347323 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0344184 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.0338752 |
| UBR1 | ubiquitin protein ligase E3 component n-recognin 1 | 0.0334831 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0331689 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0331507 |
| MCL1 | myeloid cell leukemia 1 | 0.0329422 |
| EFNB2 | ephrin-B2 | 0.0324319 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | 0.0321627 |
| STK24 | serine/threonine kinase 24 | 0.02906 |
| RAD51B | RAD51 paralog B | 0.0284114 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0283172 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0275505 |
| BICRAL | BICRA like chromatin remodeling complex associated protein | 0.0271697 |
| DIAPH1 | diaphanous-related formin 1 | 0.0270719 |
| CDHR2 | cadherin-related family member 2 | 0.0261002 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0260397 |
| SAMD12 | sterile alpha motif domain containing 12 | 0.0255312 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0254724 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0254411 |
| CCNL1 | cyclin L1 | 0.0241646 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0238974 |
| VEGFA | vascular endothelial growth factor A | 0.0236703 |
| CYSTM1 | cysteine-rich transmembrane module containing 1 | 0.0236314 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0236094 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.0230738 |
| GK | glycerol kinase | 0.0228858 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0227559 |
| RIGI | RNA sensor RIG-I | 0.0227289 |
| TSHZ2 | teashirt zinc finger homeobox 2 | 0.0226787 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0225322 |
| ITGA6 | integrin, alpha 6 | 0.0222338 |
| ERBIN | erbb2 interacting protein | 0.0217805 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0215367 |
| ARL15 | ADP-ribosylation factor-like 15 | 0.0214544 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | 0.0213796 |
| ITPKC | inositol-trisphosphate 3-kinase C | 0.0211979 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0210596 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0210279 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.020962 |
| MLPH | melanophilin | 0.0206751 |
| EXOC4 | exocyst complex component 4 | 0.0206685 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0205029 |
| SH3PXD2A | SH3 and PX domains 2A | 0.0204204 |
| KIAA1217 | KIAA1217 | 0.0203041 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0202375 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0198154 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0198016 |
| XDH | xanthine dehydrogenase | 0.0197878 |
| KIF16B | kinesin family member 16B | 0.0195141 |
| RHPN2 | rhophilin, Rho GTPase binding protein 2 | 0.0194268 |
| CORIN | corin, serine peptidase | 0.0192606 |
| SETX | senataxin | 0.0192441 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0188143 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | 0.0186392 |
| AREG | amphiregulin | 0.0186306 |
| OCLN | occludin | 0.0185999 |
| POU2F2 | POU class 2 homeobox 2 | 0.0185684 |
| TNIK | TRAF2 and NCK interacting kinase | 0.0183812 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0183118 |
| RBM47 | RNA binding motif protein 47 | 0.0182008 |
| COG3 | component of oligomeric golgi complex 3 | 0.0181026 |
| ZHX2 | zinc fingers and homeoboxes 2 | 0.0180379 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | 0.0179643 |
| DPP4 | dipeptidyl-peptidase 4 | 0.0179564 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0178781 |
| TPM3 | tropomyosin 3 | 0.0177085 |
| DNAJB14 | DnaJ (Hsp40) homolog, subfamily B, member 14 | 0.0174749 |
| SCARB1 | scavenger receptor class B, member 1 | 0.0174441 |
| FOXO1 | forkhead box O1 | 0.0171791 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | 0.0169681 |
| PADI1 | peptidyl arginine deiminase, type I | 0.016944 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0169109 |
| DUSP10 | dual specificity phosphatase 10 | 0.016748 |
| ECE1 | endothelin converting enzyme 1 | 0.0166624 |
| JAK1 | Janus kinase 1 | 0.0166535 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.0166333 |
| AKAP11 | A kinase (PRKA) anchor protein 11 | 0.0165604 |
| GSPT1 | G1 to S phase transition 1 | 0.0165228 |
| RASEF | RAS and EF-hand domain containing | 0.0164628 |
| SMARCA2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 | 0.0162602 |
| NUP58 | nucleoporin 58 | 0.0162598 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.0162255 |
| EGR1 | early growth response 1 | 0.0161811 |
| WEE1 | WEE1 G2 checkpoint kinase | 0.015723 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TPT1 | tumor protein, translationally-controlled 1 | -0.194 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.165208 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.152336 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.144807 |
| HLA-B | major histocompatibility complex, class I, B | -0.1376 |
| PTMA | prothymosin, alpha | -0.122516 |
| B2M | beta-2-microglobulin | -0.111467 |
| H1-0 | H1.0 linker histone | -0.101502 |
| TMSB10 | thymosin beta 10 | -0.0732425 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0702672 |
| TXNIP | thioredoxin interacting protein | -0.0689649 |
| C6ORF132 | chromosome 6 open reading frame 132 | -0.0687298 |
| PERP | PERP, TP53 apoptosis effector | -0.0671411 |
| UBC | ubiquitin C | -0.0623901 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0601498 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0567527 |
| HLA-C | major histocompatibility complex, class I, C | -0.0564271 |
| RPL35A | ribosomal protein L35a | -0.0547225 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.054347 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.0533266 |
| AHNAK | AHNAK nucleoprotein | -0.0532832 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0525564 |
| RPL34 | ribosomal protein L34 | -0.0523029 |
| RPS24 | ribosomal protein S24 | -0.052159 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | -0.0506286 |
| RRBP1 | ribosome binding protein 1 | -0.050358 |
| FTL | ferritin, light polypeptide | -0.0495712 |
| HLA-E | major histocompatibility complex, class I, E | -0.0492208 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0490311 |
| RPL23 | ribosomal protein L23 | -0.0487033 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0486523 |
| BTBD9 | BTB (POZ) domain containing 9 | -0.0472181 |
| LYZ | lysozyme | -0.0471012 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0467658 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0462269 |
| MT2A | metallothionein 2A | -0.0460828 |
| ENO1 | enolase 1, (alpha) | -0.0458611 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0458344 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0456776 |
| EPCAM | epithelial cell adhesion molecule | -0.0455024 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0450172 |
| RPL7L1 | ribosomal protein L7-like 1 | -0.0447017 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0443252 |
| HDLBP | high density lipoprotein binding protein | -0.0440609 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0434997 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0434553 |
| RPLP1 | ribosomal protein, large, P1 | -0.0434147 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0426934 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.042574 |
| H3-3B | H3.3 histone B | -0.0423541 |
| RNF213 | ring finger protein 213 | -0.0422679 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0421699 |
| RPL19 | ribosomal protein L19 | -0.0420606 |
| RUNX1 | runt-related transcription factor 1 | -0.0418356 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0417656 |
| ABLIM1 | actin binding LIM protein 1 | -0.0416895 |
| RBM39 | RNA binding motif protein 39 | -0.040998 |
| RPS8 | ribosomal protein S8 | -0.0408037 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0405477 |
| NF1 | neurofibromin 1 | -0.0403191 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0401139 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0399523 |
| HLA-A | major histocompatibility complex, class I, A | -0.0399143 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0390344 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0388766 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.0388195 |
| S100A10 | S100 calcium binding protein A10 | -0.0381025 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | -0.0380621 |
| RPL12 | ribosomal protein L12 | -0.037965 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | -0.0372143 |
| CANX | calnexin | -0.0371188 |
| RPL26 | ribosomal protein L26 | -0.0364823 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0364299 |
| RNF149 | ring finger protein 149 | -0.0362783 |
| MUC20 | mucin 20, cell surface associated | -0.0362291 |
| CALR | calreticulin | -0.0360229 |
| S100A6 | S100 calcium binding protein A6 | -0.0358575 |
| MKI67 | marker of proliferation Ki-67 | -0.0356986 |
| RPS19 | ribosomal protein S19 | -0.035217 |
| KLF6 | Kruppel-like factor 6 | -0.0350036 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0349003 |
| GNAS | GNAS complex locus | -0.0346618 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0341127 |
| CSTB | cystatin B (stefin B) | -0.0341062 |
| RPLP0 | ribosomal protein, large, P0 | -0.0339058 |
| TMSB4X | thymosin beta 4, X-linked | -0.0336351 |
| TPI1 | triosephosphate isomerase 1 | -0.0333793 |
| NT5C3A | 5'-nucleotidase, cytosolic IIIA | -0.0333444 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0331877 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0330092 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -0.0326203 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0320995 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0319298 |
| RPL11 | ribosomal protein L11 | -0.0318964 |
| GOLGA4 | golgin A4 | -0.0317353 |
| MT1X | metallothionein 1X | -0.0313045 |
| RPL37 | ribosomal protein L37 | -0.031239 |
| FNDC3A | fibronectin type III domain containing 3A | -0.031171 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.0311091 |
| VDAC1 | voltage-dependent anion channel 1 | -0.031038 |
