| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Lipoic acid perturbation in HEC-1-A cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Lipoic acid_HEC-1-A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.147823 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0910858 |
| GOLGA4 | golgin A4 | 0.0567633 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0524379 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0515786 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.046697 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.045095 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0443872 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0440596 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0435916 |
| HELZ | helicase with zinc finger | 0.0423239 |
| BBS9 | Bardet-Biedl syndrome 9 | 0.0388436 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.0386978 |
| CLTC | clathrin, heavy chain (Hc) | 0.037419 |
| MKI67 | marker of proliferation Ki-67 | 0.0372448 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0352073 |
| H1-0 | H1.0 linker histone | 0.0339251 |
| GOLGB1 | golgin B1 | 0.0335435 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0332441 |
| TMF1 | TATA element modulatory factor 1 | 0.0317976 |
| SEC24D | SEC24 family member D | 0.0317606 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0310872 |
| TJP1 | tight junction protein 1 | 0.0309642 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.030515 |
| COG6 | component of oligomeric golgi complex 6 | 0.0300573 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0299225 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.029796 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0292883 |
| TUSC3 | tumor suppressor candidate 3 | 0.0289209 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0288533 |
| H1-4 | H1.4 linker histone, cluster member | 0.0287737 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0283547 |
| HDLBP | high density lipoprotein binding protein | 0.0280767 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0280283 |
| PDIA5 | protein disulfide isomerase family A, member 5 | 0.0280039 |
| HYOU1 | hypoxia up-regulated 1 | 0.0278351 |
| RAB3GAP1 | RAB3 GTPase activating protein subunit 1 (catalytic) | 0.0262357 |
| BCKDHB | branched chain keto acid dehydrogenase E1, beta polypeptide | 0.0260879 |
| FNIP1 | folliculin interacting protein 1 | 0.0259813 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.0255943 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.0255859 |
| PHF3 | PHD finger protein 3 | 0.0254465 |
| NBAS | neuroblastoma amplified sequence | 0.0251863 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0251786 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.0251696 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0251549 |
| NIBAN1 | niban apoptosis regulator 1 | 0.0250744 |
| MYEOV | myeloma overexpressed | 0.0247107 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0242474 |
| SPAG9 | sperm associated antigen 9 | 0.0241617 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0241145 |
| CLINT1 | clathrin interactor 1 | 0.0240452 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.023964 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0239636 |
| JMJD1C | jumonji domain containing 1C | 0.0239379 |
| COPA | coatomer protein complex, subunit alpha | 0.0238482 |
| ATXN7 | ataxin 7 | 0.0235194 |
| MON2 | MON2 homolog (S. cerevisiae) | 0.0232935 |
| NBEA | neurobeachin | 0.022853 |
| TMEM39A | transmembrane protein 39A | 0.0224836 |
| VGLL4 | vestigial-like family member 4 | 0.0224029 |
| CDK5RAP2 | CDK5 regulatory subunit associated protein 2 | 0.022324 |
| NUP58 | nucleoporin 58 | 0.0221633 |
| RNF145 | ring finger protein 145 | 0.021968 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0219266 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0218712 |
| MAGI3 | membrane associated guanylate kinase, WW and PDZ domain containing 3 | 0.0218079 |
| RANBP2 | RAN binding protein 2 | 0.0218078 |
| SETD2 | SET domain containing 2 | 0.0217314 |
| SNX9 | sorting nexin 9 | 0.021527 |
| CANX | calnexin | 0.0214734 |
| PGM3 | phosphoglucomutase 3 | 0.0214692 |
| TBL1X | transducin (beta)-like 1X-linked | 0.0213494 |
| LARP1B | La ribonucleoprotein domain family, member 1B | 0.0212426 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0209954 |
| ARID1A | AT rich interactive domain 1A (SWI-like) | 0.0209867 |
| CREB3L2 | cAMP responsive element binding protein 3-like 2 | 0.0209507 |
| BRD2 | bromodomain containing 2 | 0.0206678 |
| TGFA | transforming growth factor, alpha | 0.0206323 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0205733 |
| LMAN1 | lectin, mannose-binding, 1 | 0.0205569 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0205264 |
| LCOR | ligand dependent nuclear receptor corepressor | 0.020351 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0203509 |
| PCM1 | pericentriolar material 1 | 0.0202375 |
| SEC61A1 | Sec61 alpha 1 subunit (S. cerevisiae) | 0.0201895 |
| INTS6 | integrator complex subunit 6 | 0.0201729 |
| SETD5 | SET domain containing 5 | 0.0200616 |
| CALR | calreticulin | 0.0199666 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0198896 |
| IARS1 | isoleucyl-tRNA synthetase 1 | 0.0198708 |
| TRA2B | transformer 2 beta homolog (Drosophila) | 0.0197553 |
| CCDC138 | coiled-coil domain containing 138 | 0.0197232 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | 0.0196354 |
| BBX | bobby sox homolog (Drosophila) | 0.0194821 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0194637 |
| ARF4 | ADP-ribosylation factor 4 | 0.0194071 |
| TXNRD1 | thioredoxin reductase 1 | 0.0193872 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0193154 |
| AFDN | afadin, adherens junction formation factor | 0.019301 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.144139 |
| PTMA | prothymosin, alpha | -0.124744 |
| ACTG1 | actin gamma 1 | -0.120189 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.113453 |
| RPL35A | ribosomal protein L35a | -0.0980409 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.097437 |
| MT2A | metallothionein 2A | -0.0885111 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0867619 |
| ASPH | aspartate beta-hydroxylase | -0.0824217 |
| FTL | ferritin, light polypeptide | -0.0809068 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0780029 |
| HMGA2 | high mobility group AT-hook 2 | -0.0747025 |
| RPS8 | ribosomal protein S8 | -0.0731841 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.072339 |
| RPS6 | ribosomal protein S6 | -0.0717367 |
| AHNAK | AHNAK nucleoprotein | -0.0691685 |
| TPM4 | tropomyosin 4 | -0.0674278 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0643178 |
| NDRG1 | N-myc downstream regulated 1 | -0.0633459 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0632346 |
| CD44 | CD44 molecule (Indian blood group) | -0.059965 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0595733 |
| RPL31 | ribosomal protein L31 | -0.057863 |
| RPS24 | ribosomal protein S24 | -0.0575668 |
| RPL23 | ribosomal protein L23 | -0.0574767 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0571538 |
| RPL9 | ribosomal protein L9 | -0.0569049 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0558248 |
| HMGA1 | high mobility group AT-hook 1 | -0.0539819 |
| S100A10 | S100 calcium binding protein A10 | -0.0509707 |
| RPL34 | ribosomal protein L34 | -0.0501361 |
| LAMA4 | laminin, alpha 4 | -0.049161 |
| RHEX | regulator of hemoglobinization and erythroid cell expansion | -0.0490608 |
| RPL12 | ribosomal protein L12 | -0.0482153 |
| RPL11 | ribosomal protein L11 | -0.0464299 |
| VCL | vinculin | -0.0463478 |
| LAMB3 | laminin, beta 3 | -0.0452722 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0450575 |
| KRT7 | keratin 7, type II | -0.0446188 |
| TMSB4X | thymosin beta 4, X-linked | -0.044557 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0445513 |
| PCED1B | PC-esterase domain containing 1B | -0.044367 |
| RPS27A | ribosomal protein S27a | -0.0427065 |
| RPL37A | ribosomal protein L37a | -0.0426557 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0424935 |
| RPS12 | ribosomal protein S12 | -0.0424729 |
| DSCAML1 | Down syndrome cell adhesion molecule like 1 | -0.0423322 |
| FLNA | filamin A, alpha | -0.0417855 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0404438 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.039349 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0392972 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0388651 |
| EGFR | epidermal growth factor receptor | -0.0387041 |
| RPL7A | ribosomal protein L7a | -0.0385948 |
| RPL37 | ribosomal protein L37 | -0.0380591 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0379472 |
| CCND1 | cyclin D1 | -0.0374508 |
| RPS29 | ribosomal protein S29 | -0.0373718 |
| RPS19 | ribosomal protein S19 | -0.0372372 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0368171 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0365925 |
| ITGA6 | integrin, alpha 6 | -0.036263 |
| ADAMTS9 | ADAM metallopeptidase with thrombospondin type 1 motif, 9 | -0.0352091 |
| EMP1 | epithelial membrane protein 1 | -0.035125 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0350162 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0338051 |
| RPL26 | ribosomal protein L26 | -0.0331914 |
| RPS17 | ribosomal protein S17 | -0.0328019 |
| RPLP2 | ribosomal protein, large, P2 | -0.0327951 |
| PAX8 | paired box 8 | -0.0326346 |
| RPS25 | ribosomal protein S25 | -0.0326253 |
| ATG7 | autophagy related 7 | -0.032625 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0325278 |
| RPL19 | ribosomal protein L19 | -0.0324849 |
| LAMC2 | laminin, gamma 2 | -0.0322628 |
| CAPN2 | calpain 2, (m/II) large subunit | -0.0322488 |
| SEPTIN7 | septin 7 | -0.0321392 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0319872 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0319724 |
| RPS3 | ribosomal protein S3 | -0.0308539 |
| SH3TC2 | SH3 domain and tetratricopeptide repeats 2 | -0.0307588 |
| RPS14 | ribosomal protein S14 | -0.0303631 |
| KRT19 | keratin 19, type I | -0.0303038 |
| HMGB1 | high mobility group box 1 | -0.0300993 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0299776 |
| RPS11 | ribosomal protein S11 | -0.0292945 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0292916 |
| RPLP1 | ribosomal protein, large, P1 | -0.0292887 |
| RPL5 | ribosomal protein L5 | -0.0291869 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | -0.0291861 |
| S100A6 | S100 calcium binding protein A6 | -0.0289896 |
| RPS13 | ribosomal protein S13 | -0.0289648 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.0287281 |
| RPL38 | ribosomal protein L38 | -0.0286393 |
| CLDN1 | claudin 1 | -0.028504 |
| DIAPH2 | diaphanous-related formin 2 | -0.0277954 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0277763 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0276327 |
| CAP1 | CAP, adenylate cyclase-associated protein 1 (yeast) | -0.0275816 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0274015 |
