| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Lipoic acid perturbation in HOP62 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Lipoic acid_HOP62 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.216749 |
| FN1 | fibronectin 1 | 0.125118 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0987134 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0492781 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0443552 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0441279 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0431205 |
| GRAMD1B | GRAM domain containing 1B | 0.0415467 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0406386 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0404895 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0399289 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0365067 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0357962 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0348828 |
| GOLGA4 | golgin A4 | 0.0330412 |
| CANX | calnexin | 0.0329655 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0324982 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0317469 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0305083 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0301361 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0299297 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.02939 |
| SEPTIN9 | septin 9 | 0.0289138 |
| ABLIM3 | actin binding LIM protein family, member 3 | 0.0288274 |
| NAV2 | neuron navigator 2 | 0.0276939 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0272574 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0269453 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0261261 |
| TNS1 | tensin 1 | 0.0250461 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0239439 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0239136 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0230413 |
| FNIP1 | folliculin interacting protein 1 | 0.022987 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.0229223 |
| INTS6 | integrator complex subunit 6 | 0.0228788 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0220706 |
| FAM13A | family with sequence similarity 13, member A | 0.0220114 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.0212432 |
| MLPH | melanophilin | 0.0210473 |
| ZNF638 | zinc finger protein 638 | 0.0204885 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 0.0203938 |
| SYAP1 | synapse associated protein 1 | 0.0203541 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0201493 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0201381 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0201328 |
| DNMBP | dynamin binding protein | 0.019981 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0193272 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0190533 |
| ATP13A3 | ATPase type 13A3 | 0.0189116 |
| VEGFA | vascular endothelial growth factor A | 0.0186237 |
| PCBP3 | poly(rC) binding protein 3 | 0.0184578 |
| TMF1 | TATA element modulatory factor 1 | 0.0184488 |
| ABHD12 | abhydrolase domain containing 12 | 0.01841 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0181271 |
| FAT1 | FAT atypical cadherin 1 | 0.0179989 |
| AHI1 | Abelson helper integration site 1 | 0.0179651 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0173299 |
| H1-4 | H1.4 linker histone, cluster member | 0.0173182 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0171012 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0168723 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0168199 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0167896 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | 0.0166744 |
| HYOU1 | hypoxia up-regulated 1 | 0.0165881 |
| PER1 | period circadian clock 1 | 0.0164506 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0164492 |
| KYNU | kynureninase | 0.0164341 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0163106 |
| GOLGB1 | golgin B1 | 0.0162525 |
| COG5 | component of oligomeric golgi complex 5 | 0.0162143 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0161659 |
| GPC5 | glypican 5 | 0.0161425 |
| TXNIP | thioredoxin interacting protein | 0.0160128 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0159425 |
| RUNX1 | runt-related transcription factor 1 | 0.0158511 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0157442 |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | 0.0157439 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.0152982 |
| CTBP2 | C-terminal binding protein 2 | 0.0152769 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0152397 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.0152296 |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) | 0.0152013 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0151261 |
| SLFN11 | schlafen family member 11 | 0.015096 |
| FOXO3 | forkhead box O3 | 0.0150879 |
| ARFGEF3 | ARFGEF family member 3 | 0.0150572 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.01488 |
| PGM3 | phosphoglucomutase 3 | 0.0148482 |
| VPS13C | vacuolar protein sorting 13 homolog C (S. cerevisiae) | 0.0147165 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0145819 |
| LOXL2 | lysyl oxidase-like 2 | 0.0145249 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0142616 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0141572 |
| RBM39 | RNA binding motif protein 39 | 0.0139552 |
| XPO1 | exportin 1 | 0.013821 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0137833 |
| PCM1 | pericentriolar material 1 | 0.0137413 |
| FAM219A | family with sequence similarity 219, member A | 0.0137072 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0136828 |
| MKI67 | marker of proliferation Ki-67 | 0.0136218 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.242581 |
| TMSB10 | thymosin beta 10 | -0.177804 |
| CDH13 | cadherin 13 | -0.139352 |
| EGR1 | early growth response 1 | -0.125471 |
| ACTG1 | actin gamma 1 | -0.118502 |
| CD44 | CD44 molecule (Indian blood group) | -0.118199 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.118108 |
| ASPH | aspartate beta-hydroxylase | -0.108309 |
| EXT1 | exostosin glycosyltransferase 1 | -0.107639 |
| NAV1 | neuron navigator 1 | -0.106745 |
| VCL | vinculin | -0.105413 |
| MYO10 | myosin X | -0.102408 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0995698 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0966825 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0950686 |
| COL6A2 | collagen, type VI, alpha 2 | -0.0945597 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0896937 |
| IGF2 | insulin-like growth factor 2 | -0.0888652 |
| NDRG1 | N-myc downstream regulated 1 | -0.0871672 |
| HMGA2 | high mobility group AT-hook 2 | -0.082423 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0769807 |
| TENM2 | teneurin transmembrane protein 2 | -0.0731629 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0697067 |
| GLIS3 | GLIS family zinc finger 3 | -0.068864 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.068663 |
| COL6A3 | collagen, type VI, alpha 3 | -0.0648404 |
| LAMB3 | laminin, beta 3 | -0.0636655 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0614775 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0597501 |
| PGK1 | phosphoglycerate kinase 1 | -0.0596463 |
| RAI14 | retinoic acid induced 14 | -0.0594192 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0592602 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0569105 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0554677 |
| DIAPH2 | diaphanous-related formin 2 | -0.0544776 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0543789 |
| PTMA | prothymosin, alpha | -0.0539893 |
| RFX8 | RFX family member 8, lacking RFX DNA binding domain | -0.0534605 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0531978 |
| AHNAK | AHNAK nucleoprotein | -0.0503728 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0501624 |
| POTEF | POTE ankyrin domain family, member F | -0.049882 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0494263 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | -0.0491493 |
| IL1B | interleukin 1, beta | -0.0478483 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.04565 |
| MMP14 | matrix metallopeptidase 14 (membrane-inserted) | -0.0456477 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0450676 |
| COL1A1 | collagen, type I, alpha 1 | -0.0447931 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0443496 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0436219 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0425364 |
| TUBB6 | tubulin, beta 6 class V | -0.041577 |
| CCDC91 | coiled-coil domain containing 91 | -0.0415586 |
| PLAUR | plasminogen activator, urokinase receptor | -0.0408984 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0405801 |
| TPM1 | tropomyosin 1 (alpha) | -0.0389582 |
| CCND1 | cyclin D1 | -0.0389434 |
| PRSS23 | protease, serine, 23 | -0.0388195 |
| STC1 | stanniocalcin 1 | -0.0388124 |
| RRM2 | ribonucleotide reductase M2 | -0.0380276 |
| ATXN1 | ataxin 1 | -0.0368571 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0367494 |
| TNNC1 | troponin C type 1 (slow) | -0.0366388 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0362084 |
| CALU | calumenin | -0.0359328 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.035863 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0357367 |
| ACTN1 | actinin, alpha 1 | -0.0357255 |
| ENO1 | enolase 1, (alpha) | -0.0349576 |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 | -0.0345799 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0340782 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0340022 |
| KIAA1549L | KIAA1549-like | -0.0336787 |
| ANTXR1 | anthrax toxin receptor 1 | -0.0331666 |
| IER3 | immediate early response 3 | -0.0329281 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0325838 |
| FRMD4A | FERM domain containing 4A | -0.0323197 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0322268 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0321618 |
| MSN | moesin | -0.0317562 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0315859 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0315203 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0313349 |
| CLMP | CXADR-like membrane protein | -0.0312898 |
| CALD1 | caldesmon 1 | -0.0309477 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0309034 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0305925 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0305608 |
| CAP1 | CAP, adenylate cyclase-associated protein 1 (yeast) | -0.0304945 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0304837 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0303207 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0302892 |
| PTK2 | protein tyrosine kinase 2 | -0.0302428 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0301314 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0299705 |
| SMC4 | structural maintenance of chromosomes 4 | -0.029743 |
| WDFY2 | WD repeat and FYVE domain containing 2 | -0.0297358 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | -0.0293193 |
| CDK14 | cyclin-dependent kinase 14 | -0.0292881 |
