| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Lipoic acid perturbation in HS-578T cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Lipoic acid_HS-578T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CADM1 | cell adhesion molecule 1 | 0.0696161 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0547175 |
| FN1 | fibronectin 1 | 0.0498624 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0449476 |
| VEGFA | vascular endothelial growth factor A | 0.0444553 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0349661 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | 0.0332339 |
| RBM39 | RNA binding motif protein 39 | 0.0301875 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0292762 |
| NAV2 | neuron navigator 2 | 0.0275788 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0274045 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.027358 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0260891 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0259159 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0252406 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.025141 |
| QKI | QKI, KH domain containing, RNA binding | 0.0251309 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0242115 |
| EGFR | epidermal growth factor receptor | 0.0238155 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | 0.0237909 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0230635 |
| HYOU1 | hypoxia up-regulated 1 | 0.021739 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0213692 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0209025 |
| PTK2 | protein tyrosine kinase 2 | 0.0207308 |
| FAM13A | family with sequence similarity 13, member A | 0.0206499 |
| NDRG1 | N-myc downstream regulated 1 | 0.020644 |
| SMAD3 | SMAD family member 3 | 0.0200448 |
| RNF145 | ring finger protein 145 | 0.0198962 |
| SPAG9 | sperm associated antigen 9 | 0.0198024 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0191966 |
| ZNF292 | zinc finger protein 292 | 0.0190704 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.0188801 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0177117 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0171192 |
| TRAM2 | translocation associated membrane protein 2 | 0.0170189 |
| RBFOX2 | RNA binding protein, fox-1 homolog (C. elegans) 2 | 0.0167566 |
| OSBPL9 | oxysterol binding protein-like 9 | 0.0165036 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0163657 |
| HIP1 | huntingtin interacting protein 1 | 0.0163187 |
| HDAC9 | histone deacetylase 9 | 0.0161554 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0157016 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.015692 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0155354 |
| MRTFA | myocardin related transcription factor A | 0.015381 |
| KHDRBS3 | KH domain containing, RNA binding, signal transduction associated 3 | 0.0153709 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0153667 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.0153571 |
| TNS1 | tensin 1 | 0.015267 |
| PDE8A | phosphodiesterase 8A | 0.0152399 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0152396 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0151605 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0150919 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0148225 |
| CABIN1 | calcineurin binding protein 1 | 0.0147795 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0147306 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0144061 |
| CD109 | CD109 molecule | 0.0143544 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0143488 |
| HELZ | helicase with zinc finger | 0.0143131 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0142173 |
| NT5DC3 | 5'-nucleotidase domain containing 3 | 0.0138852 |
| SEPTIN9 | septin 9 | 0.0138717 |
| KIF13A | kinesin family member 13A | 0.0136455 |
| OGA | O-GlcNAcase | 0.0136075 |
| PPME1 | protein phosphatase methylesterase 1 | 0.013595 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0135437 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0135084 |
| USP3 | ubiquitin specific peptidase 3 | 0.0134455 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.013423 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0133606 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0133362 |
| CTBP2 | C-terminal binding protein 2 | 0.0132217 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0131399 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0129798 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0129498 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0129064 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | 0.0128841 |
| GRID1 | glutamate receptor, ionotropic, delta 1 | 0.012766 |
| XPO1 | exportin 1 | 0.0127082 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0126657 |
| RYBP | RING1 and YY1 binding protein | 0.0126237 |
| TMF1 | TATA element modulatory factor 1 | 0.0126209 |
| RNF220 | ring finger protein 220 | 0.0125931 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0124542 |
| OXSR1 | oxidative stress responsive 1 | 0.0124354 |
| RLF | rearranged L-myc fusion | 0.0123384 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0123011 |
| YEATS2 | YEATS domain containing 2 | 0.0122532 |
| MYOF | myoferlin | 0.0121041 |
| FYN | FYN proto-oncogene, Src family tyrosine kinase | 0.0120976 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0120602 |
| CCNY | cyclin Y | 0.0120458 |
| CPEB2 | cytoplasmic polyadenylation element binding protein 2 | 0.0120458 |
| MAP4 | microtubule-associated protein 4 | 0.012023 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0120133 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.012013 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0120068 |
| AMOTL1 | angiomotin like 1 | 0.0119252 |
| PARP8 | poly (ADP-ribose) polymerase family, member 8 | 0.0118856 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.218152 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.176389 |
| COL1A1 | collagen, type I, alpha 1 | -0.174346 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.134445 |
| COL1A2 | collagen, type I, alpha 2 | -0.122345 |
| TMSB10 | thymosin beta 10 | -0.113959 |
| STC1 | stanniocalcin 1 | -0.113906 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.10629 |
| MT2A | metallothionein 2A | -0.105262 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.105105 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0965081 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0913855 |
| CDH13 | cadherin 13 | -0.0881521 |
| TPM4 | tropomyosin 4 | -0.0874935 |
| NKAIN3 | Na+/K+ transporting ATPase interacting 3 | -0.0795572 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0755883 |
| VCAN | versican | -0.0754882 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0754538 |
| FBN1 | fibrillin 1 | -0.0745902 |
| INHBA | inhibin, beta A | -0.0675965 |
| IER3 | immediate early response 3 | -0.0656581 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0647502 |
| ENO1 | enolase 1, (alpha) | -0.0621873 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0620133 |
| ACTG1 | actin gamma 1 | -0.0571407 |
| CD44 | CD44 molecule (Indian blood group) | -0.0557963 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0544012 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0543692 |
| IL6 | interleukin 6 | -0.0514643 |
| ASPH | aspartate beta-hydroxylase | -0.0496187 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0484231 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0470005 |
| CALD1 | caldesmon 1 | -0.0454271 |
| VCL | vinculin | -0.0453149 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0447773 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0430208 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.039782 |
| IGFBP7 | insulin-like growth factor binding protein 7 | -0.0396557 |
| MAP1B | microtubule-associated protein 1B | -0.0391122 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0384156 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0377285 |
| CLMP | CXADR-like membrane protein | -0.0375782 |
| RPS8 | ribosomal protein S8 | -0.037353 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0367716 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0365239 |
| HLA-B | major histocompatibility complex, class I, B | -0.0355229 |
| CALR | calreticulin | -0.0355101 |
| LDHA | lactate dehydrogenase A | -0.0345336 |
| S100A6 | S100 calcium binding protein A6 | -0.0344051 |
| TMSB4X | thymosin beta 4, X-linked | -0.0343302 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.034099 |
| GLIS3 | GLIS family zinc finger 3 | -0.0340934 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | -0.0340316 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0337628 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0335618 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0333312 |
| S100A9 | S100 calcium binding protein A9 | -0.0331172 |
| PALLD | palladin, cytoskeletal associated protein | -0.0330884 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0325843 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0323179 |
| RPL35A | ribosomal protein L35a | -0.0318124 |
| FTL | ferritin, light polypeptide | -0.0318091 |
| NAV1 | neuron navigator 1 | -0.0315792 |
| OSMR | oncostatin M receptor | -0.0311555 |
| EGR1 | early growth response 1 | -0.0310003 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0308712 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0302034 |
| CALU | calumenin | -0.0301059 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.0299592 |
| RPS6 | ribosomal protein S6 | -0.0282593 |
| B2M | beta-2-microglobulin | -0.0279859 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0279787 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.0272665 |
| RPL30 | ribosomal protein L30 | -0.0268524 |
| ARFGAP3 | ADP-ribosylation factor GTPase activating protein 3 | -0.0267017 |
| RACK1 | receptor for activated C kinase 1 | -0.0261083 |
| CLIC4 | chloride intracellular channel 4 | -0.0259521 |
| TPM1 | tropomyosin 1 (alpha) | -0.0259344 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | -0.0251433 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.024984 |
| RPLP0 | ribosomal protein, large, P0 | -0.0248693 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0248344 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0243575 |
| POTEF | POTE ankyrin domain family, member F | -0.0232767 |
| LMO4 | LIM domain only 4 | -0.0231245 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0230532 |
| CAP1 | CAP, adenylate cyclase-associated protein 1 (yeast) | -0.0227841 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0226889 |
| TPI1 | triosephosphate isomerase 1 | -0.0226639 |
| RPL8 | ribosomal protein L8 | -0.0224431 |
| RPS3 | ribosomal protein S3 | -0.0222035 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0220317 |
| RPL26 | ribosomal protein L26 | -0.0220267 |
| LOXL2 | lysyl oxidase-like 2 | -0.0218768 |
| SLC24A3 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 | -0.0215997 |
| CTSB | cathepsin B | -0.0215768 |
| ADAM12 | ADAM metallopeptidase domain 12 | -0.0214396 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0211372 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0210631 |
| RPL19 | ribosomal protein L19 | -0.0209198 |
