| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Lipoic acid perturbation in HT-29 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Lipoic acid_HT-29 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ADARB1 | adenosine deaminase, RNA-specific, B1 | 0.0810127 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0751956 |
| INTS6 | integrator complex subunit 6 | 0.0675416 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0613234 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0534547 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.0499853 |
| MCL1 | myeloid cell leukemia 1 | 0.0489095 |
| EMP1 | epithelial membrane protein 1 | 0.0469879 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0438736 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | 0.0391198 |
| CTBP2 | C-terminal binding protein 2 | 0.0379075 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0378893 |
| VEGFA | vascular endothelial growth factor A | 0.0378809 |
| VMP1 | vacuole membrane protein 1 | 0.0364621 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.0349524 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0347478 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0347404 |
| SMAD3 | SMAD family member 3 | 0.0346542 |
| ATXN1 | ataxin 1 | 0.0330253 |
| SEPTIN9 | septin 9 | 0.032983 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.0326775 |
| RND3 | Rho family GTPase 3 | 0.0302203 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | 0.0299923 |
| PRKN | parkin RBR E3 ubiquitin protein ligase | 0.0298622 |
| PCBP2 | poly(rC) binding protein 2 | 0.0293062 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.029027 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0279303 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0264961 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0259945 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0257676 |
| TRIB1 | tribbles pseudokinase 1 | 0.0249144 |
| RPL21 | ribosomal protein L21 | 0.0247872 |
| GCNT3 | glucosaminyl (N-acetyl) transferase 3, mucin type | 0.024384 |
| SGMS2 | sphingomyelin synthase 2 | 0.0234713 |
| TUFT1 | tuftelin 1 | 0.0233964 |
| VIM | vimentin | 0.0227709 |
| FAT1 | FAT atypical cadherin 1 | 0.0224619 |
| EEPD1 | endonuclease/exonuclease/phosphatase family domain containing 1 | 0.022104 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0215722 |
| RASEF | RAS and EF-hand domain containing | 0.021546 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0214067 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0213921 |
| ANXA1 | annexin A1 | 0.0213209 |
| CATSPERB | catsper channel auxiliary subunit beta | 0.0212658 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0209804 |
| MAGT1 | magnesium transporter 1 | 0.0207522 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0203973 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0203355 |
| PRR5L | proline rich 5 like | 0.0200569 |
| ATP2A2 | ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 | 0.019766 |
| LAMA4 | laminin, alpha 4 | 0.0193784 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0192009 |
| UBN2 | ubinuclein 2 | 0.0190592 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0189726 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.018384 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0179527 |
| EFNB2 | ephrin-B2 | 0.0177627 |
| TNS1 | tensin 1 | 0.0176681 |
| NABP1 | nucleic acid binding protein 1 | 0.0176262 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0174985 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 0.0174844 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0173578 |
| RPL37A | ribosomal protein L37a | 0.0173341 |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A | 0.01731 |
| UBAP2 | ubiquitin associated protein 2 | 0.017221 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0169832 |
| FAM107B | family with sequence similarity 107, member B | 0.0169764 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0169713 |
| PLK2 | polo-like kinase 2 | 0.0169317 |
| ZFP36 | ZFP36 ring finger protein | 0.0169298 |
| LARP1B | La ribonucleoprotein domain family, member 1B | 0.0168206 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0168178 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0166096 |
| CYSTM1 | cysteine-rich transmembrane module containing 1 | 0.0166078 |
| JMJD1C | jumonji domain containing 1C | 0.016559 |
| GOLGB1 | golgin B1 | 0.0164197 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0163488 |
| MYEOV | myeloma overexpressed | 0.0163073 |
| RPS3 | ribosomal protein S3 | 0.0162259 |
| AREG | amphiregulin | 0.0161191 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0161122 |
| RIGI | RNA sensor RIG-I | 0.0161102 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0160395 |
| MARCHF3 | membrane associated ring-CH-type finger 3 | 0.0159775 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.015774 |
| MPZL3 | myelin protein zero-like 3 | 0.0157381 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0157165 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0157136 |
| RPL3 | ribosomal protein L3 | 0.0156776 |
| CLDN4 | claudin 4 | 0.0155816 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0155643 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0154567 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0153237 |
| B2M | beta-2-microglobulin | 0.0152591 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | 0.0152113 |
| RPS17 | ribosomal protein S17 | 0.0150544 |
| MYADM | myeloid-associated differentiation marker | 0.0150487 |
| MYO10 | myosin X | 0.0149891 |
| POF1B | premature ovarian failure, 1B | 0.0149159 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0148916 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TPT1 | tumor protein, translationally-controlled 1 | -0.108208 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0933655 |
| NDRG1 | N-myc downstream regulated 1 | -0.0865797 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.083138 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0815242 |
| PGK1 | phosphoglycerate kinase 1 | -0.07666 |
| LYZ | lysozyme | -0.0682424 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0615496 |
| ACTN4 | actinin, alpha 4 | -0.0612526 |
| NECTIN2 | nectin cell adhesion molecule 2 | -0.0605311 |
| KRT18 | keratin 18, type I | -0.0598269 |
| AHNAK | AHNAK nucleoprotein | -0.0591179 |
| TMEM123 | transmembrane protein 123 | -0.0581677 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0569152 |
| TMSB10 | thymosin beta 10 | -0.0530914 |
| CD2AP | CD2-associated protein | -0.0525781 |
| S100A6 | S100 calcium binding protein A6 | -0.0518631 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0508896 |
| SQSTM1 | sequestosome 1 | -0.0503609 |
| ITPKC | inositol-trisphosphate 3-kinase C | -0.0500664 |
| TXNRD1 | thioredoxin reductase 1 | -0.0495828 |
| RRBP1 | ribosome binding protein 1 | -0.0490934 |
| PLAUR | plasminogen activator, urokinase receptor | -0.0488491 |
| ACACA | acetyl-CoA carboxylase alpha | -0.0482965 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0468995 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.044604 |
| NF1 | neurofibromin 1 | -0.043865 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.0421104 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -0.0418891 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0417152 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0409958 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.0398945 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0393324 |
| ZNF292 | zinc finger protein 292 | -0.0382463 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | -0.0374583 |
| ACTG1 | actin gamma 1 | -0.0373826 |
| PTMA | prothymosin, alpha | -0.0367298 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0364223 |
| MUC13 | mucin 13, cell surface associated | -0.0354462 |
| RNF213 | ring finger protein 213 | -0.0351721 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.035036 |
| FRY | furry homolog (Drosophila) | -0.0348094 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 | -0.0342254 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | -0.0338085 |
| NSMCE2 | non-SMC element 2, MMS21 homolog (S. cerevisiae) | -0.0336485 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0335431 |
| ARF1 | ADP-ribosylation factor 1 | -0.0326069 |
| CD164 | CD164 molecule, sialomucin | -0.0325614 |
| MYO6 | myosin VI | -0.0325256 |
| KLF5 | Kruppel-like factor 5 (intestinal) | -0.032304 |
| WDR45B | WD repeat domain 45B | -0.0321344 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0318308 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0317639 |
| CANX | calnexin | -0.0312535 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0311425 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0310825 |
| JUN | jun proto-oncogene | -0.0307742 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0305492 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0304185 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | -0.030366 |
| WASF2 | WAS protein family, member 2 | -0.0303163 |
| KLF3 | Kruppel-like factor 3 (basic) | -0.0300684 |
| MAL2 | mal, T-cell differentiation protein 2 (gene/pseudogene) | -0.0295744 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0294542 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0291422 |
| TM4SF4 | transmembrane 4 L six family member 4 | -0.0289935 |
| EIF3H | eukaryotic translation initiation factor 3, subunit H | -0.0287638 |
| KRT19 | keratin 19, type I | -0.0286958 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.02868 |
| MMP7 | matrix metallopeptidase 7 | -0.0282161 |
| FOXP1 | forkhead box P1 | -0.0281994 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | -0.0276618 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0275507 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0270469 |
| SPINT2 | serine peptidase inhibitor, Kunitz type, 2 | -0.0267312 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0263653 |
| HDLBP | high density lipoprotein binding protein | -0.0262168 |
| MKI67 | marker of proliferation Ki-67 | -0.0262113 |
| TMSB4X | thymosin beta 4, X-linked | -0.0259952 |
| LDHA | lactate dehydrogenase A | -0.0259748 |
| FTL | ferritin, light polypeptide | -0.0258974 |
| PIAS1 | protein inhibitor of activated STAT, 1 | -0.0258034 |
| TPM4 | tropomyosin 4 | -0.0256642 |
| RPLP1 | ribosomal protein, large, P1 | -0.0256275 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0255356 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0254655 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | -0.0251485 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0250864 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0250069 |
| ABLIM1 | actin binding LIM protein 1 | -0.0246412 |
| TJP1 | tight junction protein 1 | -0.0245184 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0242479 |
| RAB2A | RAB2A, member RAS oncogene family | -0.0241296 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0237247 |
| CAMK2D | calcium/calmodulin-dependent protein kinase II delta | -0.0236146 |
| S100A10 | S100 calcium binding protein A10 | -0.0233382 |
| LGALS4 | lectin, galactoside-binding, soluble, 4 | -0.0233235 |
| NIBAN2 | niban apoptosis regulator 2 | -0.0227922 |
| TFRC | transferrin receptor | -0.0226981 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0225812 |
