| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Lipoic acid perturbation in Hs 766T cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Lipoic acid_Hs 766T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LMO7 | LIM domain 7 | 0.160272 |
| IGF2 | insulin-like growth factor 2 | 0.0786295 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0728011 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.069551 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0661618 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0649112 |
| NDRG1 | N-myc downstream regulated 1 | 0.0591203 |
| PTK2 | protein tyrosine kinase 2 | 0.0586142 |
| TGM2 | transglutaminase 2 | 0.0541309 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0532593 |
| TXNIP | thioredoxin interacting protein | 0.0528671 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0520718 |
| RAI14 | retinoic acid induced 14 | 0.0516102 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0497389 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0491192 |
| DST | dystonin | 0.0479199 |
| PODXL | podocalyxin-like | 0.0473599 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.047127 |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | 0.0469975 |
| ITGBL1 | integrin, beta-like 1 (with EGF-like repeat domains) | 0.0466381 |
| MTSS1 | metastasis suppressor 1 | 0.045425 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0453339 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0447732 |
| TRAM1 | translocation associated membrane protein 1 | 0.0422767 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0419828 |
| BARX2 | BARX homeobox 2 | 0.0419764 |
| CDKN2A | cyclin-dependent kinase inhibitor 2A | 0.0414419 |
| FRMD6 | FERM domain containing 6 | 0.039396 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0384669 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0376401 |
| COG6 | component of oligomeric golgi complex 6 | 0.0367209 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0365319 |
| SLK | STE20-like kinase | 0.0359496 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0353313 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0352736 |
| DOCK9 | dedicator of cytokinesis 9 | 0.0352409 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0344372 |
| NUCB2 | nucleobindin 2 | 0.0342329 |
| PDLIM1 | PDZ and LIM domain 1 | 0.0337757 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0333529 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0332126 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0329182 |
| WASF2 | WAS protein family, member 2 | 0.0327431 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0322674 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0320237 |
| TMF1 | TATA element modulatory factor 1 | 0.0316322 |
| LRRC8C | leucine rich repeat containing 8 family, member C | 0.0310093 |
| ATM | ATM serine/threonine kinase | 0.0307326 |
| MAP4 | microtubule-associated protein 4 | 0.0304445 |
| BCL2L1 | BCL2-like 1 | 0.0302563 |
| FNIP1 | folliculin interacting protein 1 | 0.0300883 |
| GOLGB1 | golgin B1 | 0.03003 |
| SQLE | squalene epoxidase | 0.029879 |
| SPIRE1 | spire-type actin nucleation factor 1 | 0.0294939 |
| EZR | ezrin | 0.0294237 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 0.0293547 |
| CALB1 | calbindin 1, 28kDa | 0.0291526 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0285251 |
| CMIP | c-Maf inducing protein | 0.0284585 |
| USO1 | USO1 vesicle transport factor | 0.0283849 |
| GOLGA4 | golgin A4 | 0.0280227 |
| MEF2A | myocyte enhancer factor 2A | 0.0278956 |
| HSD17B2 | hydroxysteroid (17-beta) dehydrogenase 2 | 0.0277394 |
| KIF16B | kinesin family member 16B | 0.0277274 |
| VEGFA | vascular endothelial growth factor A | 0.0277067 |
| CLU | clusterin | 0.0274977 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0274061 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0273681 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0270815 |
| ITGB4 | integrin, beta 4 | 0.0269484 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.0265497 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0261715 |
| COG5 | component of oligomeric golgi complex 5 | 0.026107 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0260643 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0258162 |
| ETS2 | v-ets avian erythroblastosis virus E26 oncogene homolog 2 | 0.0257938 |
| RNF217 | ring finger protein 217 | 0.0257497 |
| LAMA5 | laminin, alpha 5 | 0.0256144 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | 0.0251796 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | 0.0249122 |
| VEGFC | vascular endothelial growth factor C | 0.0248457 |
| RAB22A | RAB22A, member RAS oncogene family | 0.0247861 |
| RPS6KC1 | ribosomal protein S6 kinase, 52kDa, polypeptide 1 | 0.0247368 |
| DSPP | dentin sialophosphoprotein | 0.0245433 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0245289 |
| IRAK2 | interleukin-1 receptor-associated kinase 2 | 0.0245092 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0244769 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.024169 |
| UBN2 | ubinuclein 2 | 0.0237008 |
| PGM3 | phosphoglucomutase 3 | 0.0235847 |
| ITGAV | integrin, alpha V | 0.0235165 |
| SEPTIN9 | septin 9 | 0.0235165 |
| FAM107B | family with sequence similarity 107, member B | 0.0230549 |
| GPR176 | G protein-coupled receptor 176 | 0.022958 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0227661 |
| WEE1 | WEE1 G2 checkpoint kinase | 0.0224874 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | 0.0224727 |
| RNF145 | ring finger protein 145 | 0.0223613 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0223362 |
| SLTM | SAFB-like, transcription modulator | 0.0220917 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.127056 |
| AHNAK | AHNAK nucleoprotein | -0.12573 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.12193 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.115756 |
| RIGI | RNA sensor RIG-I | -0.107525 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.106913 |
| TMSB4X | thymosin beta 4, X-linked | -0.0896334 |
| PTMA | prothymosin, alpha | -0.0882148 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0838385 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0834918 |
| UBC | ubiquitin C | -0.0818175 |
| RPS21 | ribosomal protein S21 | -0.072894 |
| TMSB10 | thymosin beta 10 | -0.0698155 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0697699 |
| RPS8 | ribosomal protein S8 | -0.066411 |
| STC1 | stanniocalcin 1 | -0.0645531 |
| RPS24 | ribosomal protein S24 | -0.062756 |
| VCL | vinculin | -0.0627304 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0620227 |
| B2M | beta-2-microglobulin | -0.0617846 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0616844 |
| ACTN4 | actinin, alpha 4 | -0.0611612 |
| RPS27A | ribosomal protein S27a | -0.0606118 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0602113 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0599554 |
| KIAA1217 | KIAA1217 | -0.057531 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0575281 |
| KRT17 | keratin 17, type I | -0.0567997 |
| RPL23 | ribosomal protein L23 | -0.0557826 |
| ENO1 | enolase 1, (alpha) | -0.0545676 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0540318 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0525449 |
| SQSTM1 | sequestosome 1 | -0.0522036 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0513699 |
| EGR1 | early growth response 1 | -0.0513447 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | -0.0494749 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0494127 |
| RPL11 | ribosomal protein L11 | -0.0493389 |
| SULF1 | sulfatase 1 | -0.0493002 |
| ACTG1 | actin gamma 1 | -0.0489581 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | -0.0486969 |
| FLNA | filamin A, alpha | -0.0484247 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0475098 |
| RPL19 | ribosomal protein L19 | -0.0468436 |
| RPLP1 | ribosomal protein, large, P1 | -0.0457525 |
| RPS3 | ribosomal protein S3 | -0.0441405 |
| POTEF | POTE ankyrin domain family, member F | -0.0433621 |
| NEK7 | NIMA-related kinase 7 | -0.0426833 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0422267 |
| RPLP2 | ribosomal protein, large, P2 | -0.0420824 |
| HLA-B | major histocompatibility complex, class I, B | -0.0420276 |
| CAP1 | CAP, adenylate cyclase-associated protein 1 (yeast) | -0.0412995 |
| S100A10 | S100 calcium binding protein A10 | -0.0411166 |
| FN1 | fibronectin 1 | -0.0403232 |
| PITPNB | phosphatidylinositol transfer protein, beta | -0.0402683 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0399672 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0399415 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0386617 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0386042 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0375544 |
| ANKRD33B | ankyrin repeat domain 33B | -0.0375467 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0359138 |
| RPS12 | ribosomal protein S12 | -0.0357834 |
| C4BPB | complement component 4 binding protein, beta | -0.0357195 |
| LMNA | lamin A/C | -0.0354514 |
| SET | SET nuclear proto-oncogene | -0.0348628 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0347513 |
| SMYD3 | SET and MYND domain containing 3 | -0.0342458 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0342176 |
| RPL37A | ribosomal protein L37a | -0.0341895 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | -0.0341138 |
| IER3 | immediate early response 3 | -0.0335964 |
| CSE1L | CSE1 chromosome segregation 1-like (yeast) | -0.0335867 |
| RPL37 | ribosomal protein L37 | -0.0334425 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.0333833 |
| MT2A | metallothionein 2A | -0.0332611 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.032893 |
| EMP1 | epithelial membrane protein 1 | -0.0327158 |
| TPX2 | TPX2, microtubule-associated | -0.0327039 |
| FOXP1 | forkhead box P1 | -0.0326571 |
| RPL34 | ribosomal protein L34 | -0.0325125 |
| GNAS | GNAS complex locus | -0.0325122 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0324847 |
| YBX3 | Y box binding protein 3 | -0.0323763 |
| RPS25 | ribosomal protein S25 | -0.0323398 |
| SDCBP | syndecan binding protein (syntenin) | -0.0318813 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0314449 |
| RPL9 | ribosomal protein L9 | -0.0310889 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0308001 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | -0.0304729 |
| RPS13 | ribosomal protein S13 | -0.0304679 |
| SOX13 | SRY (sex determining region Y)-box 13 | -0.0301097 |
| RPL26 | ribosomal protein L26 | -0.0301066 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | -0.0300367 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0299274 |
| CENPF | centromere protein F, 350/400kDa | -0.0297589 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0295442 |
| IRF1 | interferon regulatory factor 1 | -0.0291134 |
| RPL7A | ribosomal protein L7a | -0.0287833 |
| HMGB1 | high mobility group box 1 | -0.0284812 |
