| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Lipoic acid perturbation in LS 180 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Lipoic acid_LS 180 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MUC6 | mucin 6, oligomeric mucus/gel-forming | 0.216972 |
| ITGA6 | integrin, alpha 6 | 0.128542 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.115455 |
| FAT1 | FAT atypical cadherin 1 | 0.115091 |
| LMO7 | LIM domain 7 | 0.0873124 |
| VEGFA | vascular endothelial growth factor A | 0.0859204 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | 0.0794454 |
| NDRG1 | N-myc downstream regulated 1 | 0.0618368 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0606986 |
| EZR | ezrin | 0.0590945 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.055202 |
| TXNIP | thioredoxin interacting protein | 0.053161 |
| PTEN | phosphatase and tensin homolog | 0.0516832 |
| DSPP | dentin sialophosphoprotein | 0.0497086 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0477661 |
| CALB1 | calbindin 1, 28kDa | 0.0433606 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0433348 |
| MED13 | mediator complex subunit 13 | 0.0414793 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0401063 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | 0.039571 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0388165 |
| CD47 | CD47 molecule | 0.03746 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0364725 |
| SLK | STE20-like kinase | 0.0349306 |
| PCBP2 | poly(rC) binding protein 2 | 0.0348097 |
| LGR4 | leucine-rich repeat containing G protein-coupled receptor 4 | 0.0343273 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | 0.0342418 |
| RNF145 | ring finger protein 145 | 0.034092 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0340753 |
| ANXA1 | annexin A1 | 0.0339878 |
| MUC17 | mucin 17, cell surface associated | 0.0331921 |
| GOLGB1 | golgin B1 | 0.0331064 |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 | 0.0329718 |
| MUC5B | mucin 5B, oligomeric mucus/gel-forming | 0.0329526 |
| RNF217 | ring finger protein 217 | 0.032632 |
| CCNY | cyclin Y | 0.0326074 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0325287 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0318949 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.031348 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | 0.0303098 |
| POTEF | POTE ankyrin domain family, member F | 0.0302206 |
| EMP1 | epithelial membrane protein 1 | 0.0291938 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0285582 |
| COG6 | component of oligomeric golgi complex 6 | 0.0283292 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0283074 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0282827 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0277719 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0274052 |
| ASPH | aspartate beta-hydroxylase | 0.026991 |
| COPA | coatomer protein complex, subunit alpha | 0.0269812 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0267975 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0267283 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0261377 |
| SVIL | supervillin | 0.0259354 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0258605 |
| CALR | calreticulin | 0.0254717 |
| LMNA | lamin A/C | 0.0254408 |
| PPARG | peroxisome proliferator-activated receptor gamma | 0.0252779 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0249829 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | 0.0245971 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0241917 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0240281 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0239442 |
| NAB1 | NGFI-A binding protein 1 (EGR1 binding protein 1) | 0.0237363 |
| GRIN2B | glutamate receptor, ionotropic, N-methyl D-aspartate 2B | 0.0235694 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0234385 |
| HMGA1 | high mobility group AT-hook 1 | 0.0234182 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0230277 |
| CLOCK | clock circadian regulator | 0.0229948 |
| ZNF148 | zinc finger protein 148 | 0.0224306 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0221608 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0221298 |
| CYB5R3 | cytochrome b5 reductase 3 | 0.0221265 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0219298 |
| CLCN3 | chloride channel, voltage-sensitive 3 | 0.0217217 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0216601 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | 0.0213435 |
| CLDN7 | claudin 7 | 0.0212174 |
| TNIK | TRAF2 and NCK interacting kinase | 0.0211607 |
| FAM13A | family with sequence similarity 13, member A | 0.0210405 |
| RIC1 | RAB6A GEF complex partner 1 | 0.0209599 |
| ERBIN | erbb2 interacting protein | 0.0208964 |
| FAM120A | family with sequence similarity 120A | 0.020814 |
| ARHGAP12 | Rho GTPase activating protein 12 | 0.020597 |
| UBN2 | ubinuclein 2 | 0.0205126 |
| TMF1 | TATA element modulatory factor 1 | 0.0204683 |
| RCOR1 | REST corepressor 1 | 0.0202382 |
| ITGB4 | integrin, beta 4 | 0.020227 |
| PER2 | period circadian clock 2 | 0.0201602 |
| FNBP4 | formin binding protein 4 | 0.0201575 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0201276 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0200962 |
| CDC42BPB | CDC42 binding protein kinase beta (DMPK-like) | 0.0197406 |
| NUCB2 | nucleobindin 2 | 0.0195956 |
| ZFP36L2 | ZFP36 ring finger protein-like 2 | 0.0195885 |
| SBF2 | SET binding factor 2 | 0.0195323 |
| DNM2 | dynamin 2 | 0.0192902 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.0192723 |
| ZFP36 | ZFP36 ring finger protein | 0.0191881 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0191307 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.166415 |
| VCL | vinculin | -0.151555 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.135108 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.129045 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.116845 |
| AHNAK | AHNAK nucleoprotein | -0.0996204 |
| PTMA | prothymosin, alpha | -0.0863202 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0856579 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.080561 |
| RPS24 | ribosomal protein S24 | -0.0643577 |
| RPL34 | ribosomal protein L34 | -0.0560268 |
| RPLP1 | ribosomal protein, large, P1 | -0.0539502 |
| ONECUT3 | one cut homeobox 3 | -0.0529588 |
| NPSR1 | neuropeptide S receptor 1 | -0.0522528 |
| RPL35A | ribosomal protein L35a | -0.0499417 |
| PIGR | polymeric immunoglobulin receptor | -0.0489952 |
| TMSB10 | thymosin beta 10 | -0.0484122 |
| RPL26 | ribosomal protein L26 | -0.0478109 |
| RNF43 | ring finger protein 43 | -0.0476444 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.0469545 |
| RPLP0 | ribosomal protein, large, P0 | -0.0469284 |
| IER3 | immediate early response 3 | -0.0453532 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0448799 |
| ACTG1 | actin gamma 1 | -0.0448757 |
| RPL12 | ribosomal protein L12 | -0.0447177 |
| KLF5 | Kruppel-like factor 5 (intestinal) | -0.0442175 |
| ACTN4 | actinin, alpha 4 | -0.0435693 |
| MYO1E | myosin IE | -0.0432882 |
| RPL4 | ribosomal protein L4 | -0.0414125 |
| TNS4 | tensin 4 | -0.0408927 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0405561 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0401316 |
| MYO1D | myosin ID | -0.0392145 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0372873 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0372457 |
| EPCAM | epithelial cell adhesion molecule | -0.0360638 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0359769 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 | -0.035613 |
| RPS27A | ribosomal protein S27a | -0.0348996 |
| PDLIM5 | PDZ and LIM domain 5 | -0.034371 |
| ARF1 | ADP-ribosylation factor 1 | -0.034104 |
| RPL19 | ribosomal protein L19 | -0.0333079 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0331069 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0328189 |
| TPM4 | tropomyosin 4 | -0.0325508 |
| RPS6 | ribosomal protein S6 | -0.0322854 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0318635 |
| GPHN | gephyrin | -0.0318456 |
| TFRC | transferrin receptor | -0.0317833 |
| PKP2 | plakophilin 2 | -0.0317471 |
| RPL11 | ribosomal protein L11 | -0.0312116 |
| CCND1 | cyclin D1 | -0.0312086 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0306431 |
| RPLP2 | ribosomal protein, large, P2 | -0.0303304 |
| SMYD3 | SET and MYND domain containing 3 | -0.0303132 |
| NFIA | nuclear factor I/A | -0.0303062 |
| RPL23 | ribosomal protein L23 | -0.0302882 |
| RPS8 | ribosomal protein S8 | -0.030182 |
| RPL9 | ribosomal protein L9 | -0.0300607 |
| ANXA2 | annexin A2 | -0.0298079 |
| RPL30 | ribosomal protein L30 | -0.0297564 |
| SENP5 | SUMO1/sentrin specific peptidase 5 | -0.0297248 |
| FHIT | fragile histidine triad | -0.0294231 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0294041 |
| RACK1 | receptor for activated C kinase 1 | -0.0293491 |
| CANX | calnexin | -0.0291079 |
| PALLD | palladin, cytoskeletal associated protein | -0.0290753 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0284219 |
| HNRNPAB | heterogeneous nuclear ribonucleoprotein A/B | -0.0282505 |
| RAB10 | RAB10, member RAS oncogene family | -0.0281483 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.027973 |
| RPS25 | ribosomal protein S25 | -0.0278647 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0270233 |
| KLF6 | Kruppel-like factor 6 | -0.02692 |
| EGR1 | early growth response 1 | -0.0267712 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0265549 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0264141 |
| FHL2 | four and a half LIM domains 2 | -0.0263621 |
| TSPAN8 | tetraspanin 8 | -0.0262751 |
| RESF1 | retroelement silencing factor 1 | -0.0260277 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0260106 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | -0.0259892 |
| RPL32 | ribosomal protein L32 | -0.0259809 |
| RPL13A | ribosomal protein L13a | -0.0259805 |
| HDAC2 | histone deacetylase 2 | -0.025828 |
| S100A10 | S100 calcium binding protein A10 | -0.0257008 |
| RPL31 | ribosomal protein L31 | -0.0256928 |
| CD44 | CD44 molecule (Indian blood group) | -0.0256873 |
| MTAP | methylthioadenosine phosphorylase | -0.0252641 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0250923 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0250018 |
| RPL37 | ribosomal protein L37 | -0.0245444 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0243041 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | -0.0242703 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0241874 |
| H1-0 | H1.0 linker histone | -0.0241647 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.02416 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0240643 |
| RPS21 | ribosomal protein S21 | -0.0240094 |
| RPS20 | ribosomal protein S20 | -0.0237873 |
