| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Lipoic acid perturbation in MIA PaCa-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Lipoic acid_MIA PaCa-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| DST | dystonin | 0.0924798 |
| POTEF | POTE ankyrin domain family, member F | 0.063192 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0450279 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0442131 |
| TXNIP | thioredoxin interacting protein | 0.0439242 |
| CAPRIN2 | caprin family member 2 | 0.0412957 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0384023 |
| PCBP2 | poly(rC) binding protein 2 | 0.0364081 |
| EZR | ezrin | 0.0354334 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0353451 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0350409 |
| PRELID2 | PRELI domain containing 2 | 0.03148 |
| DPYD | dihydropyrimidine dehydrogenase | 0.0314683 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0304499 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0289325 |
| RAB27B | RAB27B, member RAS oncogene family | 0.027764 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0277418 |
| CCNL1 | cyclin L1 | 0.0275609 |
| SLK | STE20-like kinase | 0.027539 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0270376 |
| SMYD3 | SET and MYND domain containing 3 | 0.0263388 |
| RAD51B | RAD51 paralog B | 0.0260263 |
| FOSL1 | FOS-like antigen 1 | 0.0259821 |
| VMP1 | vacuole membrane protein 1 | 0.0257964 |
| SRSF11 | serine/arginine-rich splicing factor 11 | 0.0255459 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0255359 |
| CALD1 | caldesmon 1 | 0.0250082 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0248823 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0248515 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0247823 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.024768 |
| MSN | moesin | 0.0237206 |
| RNF213 | ring finger protein 213 | 0.0236699 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0235341 |
| ASPH | aspartate beta-hydroxylase | 0.0234892 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0232878 |
| MKI67 | marker of proliferation Ki-67 | 0.0232211 |
| UBXN4 | UBX domain protein 4 | 0.0230535 |
| PLEKHA4 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4 | 0.0225828 |
| HLA-A | major histocompatibility complex, class I, A | 0.0225497 |
| TNFRSF6B | tumor necrosis factor receptor superfamily, member 6b, decoy | 0.0224032 |
| TP63 | tumor protein p63 | 0.0220852 |
| OPTN | optineurin | 0.0219096 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0207328 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | 0.0203257 |
| XPO1 | exportin 1 | 0.0198932 |
| BRD2 | bromodomain containing 2 | 0.0198622 |
| VEGFC | vascular endothelial growth factor C | 0.0197702 |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | 0.019588 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | 0.0195854 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0195301 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.0194565 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0193226 |
| ECPAS | Ecm29 proteasome adaptor and scaffold | 0.0193203 |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.0193195 |
| BCAS3 | breast carcinoma amplified sequence 3 | 0.0191814 |
| F2R | coagulation factor II (thrombin) receptor | 0.0190671 |
| VEGFA | vascular endothelial growth factor A | 0.0188128 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0184521 |
| SMC4 | structural maintenance of chromosomes 4 | 0.018293 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0182081 |
| CENPF | centromere protein F, 350/400kDa | 0.0181431 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0180522 |
| CEP128 | centrosomal protein 128kDa | 0.0180393 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0180086 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0179794 |
| FERMT1 | fermitin family member 1 | 0.0179285 |
| DDX41 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 41 | 0.0179097 |
| SYAP1 | synapse associated protein 1 | 0.0173846 |
| CUBN | cubilin (intrinsic factor-cobalamin receptor) | 0.017261 |
| SLCO1B3 | solute carrier organic anion transporter family, member 1B3 | 0.0171624 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0165897 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0165086 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0163523 |
| USP11 | ubiquitin specific peptidase 11 | 0.016305 |
| NDRG1 | N-myc downstream regulated 1 | 0.0162787 |
| COPA | coatomer protein complex, subunit alpha | 0.0162515 |
| EXOC4 | exocyst complex component 4 | 0.0162268 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0162046 |
| PDE10A | phosphodiesterase 10A | 0.0161524 |
| GRIPAP1 | GRIP1 associated protein 1 | 0.0161292 |
| SRPK2 | SRSF protein kinase 2 | 0.016036 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0160318 |
| SETX | senataxin | 0.0159967 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0159425 |
| SKIL | SKI-like proto-oncogene | 0.0159092 |
| PGM3 | phosphoglucomutase 3 | 0.0158714 |
| DEK | DEK proto-oncogene | 0.0158058 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0157532 |
| NT5E | 5'-nucleotidase, ecto (CD73) | 0.0157389 |
| MYH10 | myosin, heavy chain 10, non-muscle | 0.0155582 |
| BLTP1 | bridge-like lipid transfer protein family member 1 | 0.0155538 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.0153586 |
| GOLGB1 | golgin B1 | 0.0151989 |
| RTTN | rotatin | 0.0150047 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.014949 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0149223 |
| PRKCI | protein kinase C, iota | 0.0148177 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.014812 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0147436 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.277078 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.229222 |
| TMSB10 | thymosin beta 10 | -0.148408 |
| VIM | vimentin | -0.131931 |
| TMSB4X | thymosin beta 4, X-linked | -0.116251 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.101916 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0988269 |
| PTMA | prothymosin, alpha | -0.0955197 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0771432 |
| AHNAK | AHNAK nucleoprotein | -0.0757763 |
| CD44 | CD44 molecule (Indian blood group) | -0.0748841 |
| RPL35A | ribosomal protein L35a | -0.0743664 |
| EHBP1 | EH domain binding protein 1 | -0.0666883 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0633972 |
| APP | amyloid beta (A4) precursor protein | -0.0573909 |
| ACTG1 | actin gamma 1 | -0.0551877 |
| RPS24 | ribosomal protein S24 | -0.0522168 |
| RPS8 | ribosomal protein S8 | -0.0509323 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0505605 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.049597 |
| RPS27A | ribosomal protein S27a | -0.0476084 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0471401 |
| RPL12 | ribosomal protein L12 | -0.0470012 |
| RPL23 | ribosomal protein L23 | -0.0454668 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0437721 |
| TXNRD1 | thioredoxin reductase 1 | -0.0432729 |
| EREG | epiregulin | -0.0428768 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0428365 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0423916 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0419933 |
| RPL26 | ribosomal protein L26 | -0.0416125 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0398769 |
| RACK1 | receptor for activated C kinase 1 | -0.0387432 |
| PGK1 | phosphoglycerate kinase 1 | -0.0386917 |
| RPLP0 | ribosomal protein, large, P0 | -0.0383766 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0381301 |
| ZNF217 | zinc finger protein 217 | -0.037931 |
| MT1X | metallothionein 1X | -0.0377854 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0370793 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0367008 |
| TMEM123 | transmembrane protein 123 | -0.0365307 |
| RPL19 | ribosomal protein L19 | -0.0362787 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0357037 |
| RPLP1 | ribosomal protein, large, P1 | -0.0355761 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0355221 |
| MYOF | myoferlin | -0.0350047 |
| SRGN | serglycin | -0.0345041 |
| EPHA4 | EPH receptor A4 | -0.034304 |
| GNAS | GNAS complex locus | -0.0342687 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0340694 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0336799 |
| RPL7A | ribosomal protein L7a | -0.0324418 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0321961 |
| CANX | calnexin | -0.0319879 |
| CAVIN1 | caveolae associated protein 1 | -0.0316158 |
| USP34 | ubiquitin specific peptidase 34 | -0.0312248 |
| RPL8 | ribosomal protein L8 | -0.0311427 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | -0.030705 |
| KLF6 | Kruppel-like factor 6 | -0.0305878 |
| RPS25 | ribosomal protein S25 | -0.030203 |
| SERPINB9 | serpin peptidase inhibitor, clade B (ovalbumin), member 9 | -0.0301863 |
| STK17A | serine/threonine kinase 17a | -0.0298448 |
| RPL38 | ribosomal protein L38 | -0.0297662 |
| RPL4 | ribosomal protein L4 | -0.0294472 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | -0.028916 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.028824 |
| FTL | ferritin, light polypeptide | -0.0287129 |
| NPR2 | natriuretic peptide receptor 2 | -0.0280062 |
| S100A10 | S100 calcium binding protein A10 | -0.0278522 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0278074 |
| TFRC | transferrin receptor | -0.0276002 |
| RPL18 | ribosomal protein L18 | -0.0273479 |
| RPS21 | ribosomal protein S21 | -0.0272187 |
| RPL37 | ribosomal protein L37 | -0.0271953 |
| RPS23 | ribosomal protein S23 | -0.0270803 |
| RPL37A | ribosomal protein L37a | -0.0264258 |
| RPS13 | ribosomal protein S13 | -0.0263865 |
| ZDHHC14 | zinc finger, DHHC-type containing 14 | -0.0263733 |
| RPL11 | ribosomal protein L11 | -0.0261418 |
| RPL5 | ribosomal protein L5 | -0.0260479 |
| NEK10 | NIMA-related kinase 10 | -0.0259183 |
| EFNA5 | ephrin-A5 | -0.0258401 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.0256892 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0252313 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0250501 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0250139 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0249166 |
| NAV2 | neuron navigator 2 | -0.0248043 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0246268 |
| RPL34 | ribosomal protein L34 | -0.0245024 |
| WDR45B | WD repeat domain 45B | -0.024373 |
| CDK13 | cyclin-dependent kinase 13 | -0.0241362 |
| RPS16 | ribosomal protein S16 | -0.0235704 |
| ANXA1 | annexin A1 | -0.0235267 |
| RPL27A | ribosomal protein L27a | -0.0233488 |
| RPL31 | ribosomal protein L31 | -0.0232842 |
| RPL6 | ribosomal protein L6 | -0.0232012 |
| RPS20 | ribosomal protein S20 | -0.0231071 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0230053 |
| DENND1A | DENN/MADD domain containing 1A | -0.0227771 |
