| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Lipoic acid perturbation in NCI-H1573 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Lipoic acid_NCI-H1573 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| THSD4 | thrombospondin, type I, domain containing 4 | 0.149727 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.138408 |
| FAM13A | family with sequence similarity 13, member A | 0.133616 |
| GRAMD1B | GRAM domain containing 1B | 0.105868 |
| FNDC3B | fibronectin type III domain containing 3B | 0.090956 |
| INTS6 | integrator complex subunit 6 | 0.0878845 |
| ASPH | aspartate beta-hydroxylase | 0.087333 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0802556 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0743735 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0674972 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0656679 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0640411 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0620056 |
| SMAD3 | SMAD family member 3 | 0.0609653 |
| PDE8A | phosphodiesterase 8A | 0.0599765 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0597541 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0566417 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.055347 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0528501 |
| ANKRD37 | ankyrin repeat domain 37 | 0.0528109 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0504139 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.05003 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0489344 |
| PCBP2 | poly(rC) binding protein 2 | 0.048312 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0470752 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0468826 |
| PM20D1 | peptidase M20 domain containing 1 | 0.0460474 |
| NDRG1 | N-myc downstream regulated 1 | 0.0449385 |
| BRD2 | bromodomain containing 2 | 0.04247 |
| SEC61G | Sec61 gamma subunit | 0.0408034 |
| ARRDC3 | arrestin domain containing 3 | 0.0401338 |
| HYOU1 | hypoxia up-regulated 1 | 0.0400973 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0396509 |
| MSN | moesin | 0.0392982 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0389941 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0384033 |
| MYOF | myoferlin | 0.0382916 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0382115 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0376555 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0367843 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0367509 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0367053 |
| RNF145 | ring finger protein 145 | 0.0363044 |
| UVRAG | UV radiation resistance associated | 0.0357733 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | 0.0357713 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0344377 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0337823 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0335563 |
| MCL1 | myeloid cell leukemia 1 | 0.0334187 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0332689 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.0331702 |
| ANXA1 | annexin A1 | 0.0330126 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.032956 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0327221 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0326122 |
| HELZ | helicase with zinc finger | 0.0326008 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0318913 |
| KCMF1 | potassium channel modulatory factor 1 | 0.0318327 |
| SLK | STE20-like kinase | 0.0314662 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0314374 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0312754 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0311202 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0309399 |
| CTBP2 | C-terminal binding protein 2 | 0.0309186 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | 0.0306372 |
| NTSR1 | neurotensin receptor 1 (high affinity) | 0.0306019 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0297072 |
| SFPQ | splicing factor proline/glutamine-rich | 0.029482 |
| CAPZA2 | capping protein (actin filament) muscle Z-line, alpha 2 | 0.029363 |
| TPD52 | tumor protein D52 | 0.0288179 |
| VEGFC | vascular endothelial growth factor C | 0.0287572 |
| SCEL | sciellin | 0.0285498 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0285389 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | 0.0282206 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0281249 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0276261 |
| HOMER1 | homer scaffolding protein 1 | 0.0275685 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0270907 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.027039 |
| LRP12 | low density lipoprotein receptor-related protein 12 | 0.0268864 |
| IFI44L | interferon-induced protein 44-like | 0.0268326 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0267811 |
| GPHN | gephyrin | 0.0264146 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0261824 |
| DTNA | dystrobrevin, alpha | 0.0257866 |
| RAD51B | RAD51 paralog B | 0.0256724 |
| DNAJB11 | DnaJ (Hsp40) homolog, subfamily B, member 11 | 0.0253358 |
| ATF6 | activating transcription factor 6 | 0.0253209 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0249348 |
| ENO1 | enolase 1, (alpha) | 0.0248885 |
| PTK2 | protein tyrosine kinase 2 | 0.0248332 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0247937 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0246158 |
| SMOC1 | SPARC related modular calcium binding 1 | 0.0244945 |
| STC1 | stanniocalcin 1 | 0.024299 |
| GOLGA4 | golgin A4 | 0.0241527 |
| RNF213 | ring finger protein 213 | 0.0241318 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.024037 |
| PTMA | prothymosin, alpha | 0.0236184 |
| STC2 | stanniocalcin 2 | 0.0234935 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TXNRD1 | thioredoxin reductase 1 | -0.171826 |
| OSMR | oncostatin M receptor | -0.11614 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.112329 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0975766 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.093306 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0768711 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0756343 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0733291 |
| LAMC2 | laminin, gamma 2 | -0.0666975 |
| TMSB10 | thymosin beta 10 | -0.0636931 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0620578 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0617148 |
| ACTG1 | actin gamma 1 | -0.060708 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.0508676 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0505616 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0494965 |
| HDLBP | high density lipoprotein binding protein | -0.0490413 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0486216 |
| GM2A | GM2 ganglioside activator | -0.0482603 |
| NPC1 | Niemann-Pick disease, type C1 | -0.0480802 |
| MKI67 | marker of proliferation Ki-67 | -0.0480608 |
| AHNAK | AHNAK nucleoprotein | -0.0458717 |
| PGK1 | phosphoglycerate kinase 1 | -0.0457865 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0456824 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0431588 |
| MGAT4C | MGAT4 family, member C | -0.0431223 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | -0.0394574 |
| EGR1 | early growth response 1 | -0.0376633 |
| TES | testin LIM domain protein | -0.0374259 |
| MGST1 | microsomal glutathione S-transferase 1 | -0.0372289 |
| H1-0 | H1.0 linker histone | -0.0371063 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0369305 |
| ANKLE2 | ankyrin repeat and LEM domain containing 2 | -0.0359926 |
| LAMA4 | laminin, alpha 4 | -0.0353137 |
| CAMTA1 | calmodulin binding transcription activator 1 | -0.0352323 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0351503 |
| RPS24 | ribosomal protein S24 | -0.0348759 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | -0.0339038 |
| BMAL2 | basic helix-loop-helix ARNT like 2 | -0.0331486 |
| AGO2 | argonaute RISC catalytic component 2 | -0.0331007 |
| KMT2A | lysine (K)-specific methyltransferase 2A | -0.0330053 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0326246 |
| TPTEP2-CSNK1E | TPTEP2-CSNK1E readthrough | -0.0323355 |
| RPL35A | ribosomal protein L35a | -0.0320549 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -0.0317088 |
| KRT18 | keratin 18, type I | -0.0316823 |
| EGFR | epidermal growth factor receptor | -0.0314298 |
| TKT | transketolase | -0.0308696 |
| LMO7 | LIM domain 7 | -0.0308502 |
| S100A10 | S100 calcium binding protein A10 | -0.0303856 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0298731 |
| SENP5 | SUMO1/sentrin specific peptidase 5 | -0.0296911 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0296023 |
| HLA-B | major histocompatibility complex, class I, B | -0.0295079 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0290303 |
| SCLT1 | sodium channel and clathrin linker 1 | -0.0288866 |
| ZC3H11A | zinc finger CCCH-type containing 11A | -0.0288592 |
| MARF1 | meiosis regulator and mRNA stability factor 1 | -0.0282479 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0282202 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0281979 |
| RPL34 | ribosomal protein L34 | -0.0276029 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0274409 |
| RPL4 | ribosomal protein L4 | -0.0274296 |
| RNF169 | ring finger protein 169 | -0.0273627 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0273461 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0267268 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0266266 |
| ABLIM1 | actin binding LIM protein 1 | -0.0263738 |
| KIAA1328 | KIAA1328 | -0.0261507 |
| NGLY1 | N-glycanase 1 | -0.0261455 |
| PERP | PERP, TP53 apoptosis effector | -0.0254512 |
| S100A11 | S100 calcium binding protein A11 | -0.0252602 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0251726 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0250323 |
| RAB27B | RAB27B, member RAS oncogene family | -0.024962 |
| RAP2B | RAP2B, member of RAS oncogene family | -0.0248455 |
| SMIM14 | small integral membrane protein 14 | -0.0245084 |
| SDC4 | syndecan 4 | -0.0239487 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0236844 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0233137 |
| RTN4 | reticulon 4 | -0.023283 |
| CANX | calnexin | -0.0232478 |
| ADAR | adenosine deaminase, RNA-specific | -0.0231078 |
| IER3 | immediate early response 3 | -0.0228543 |
| ADGRF1 | adhesion G protein-coupled receptor F1 | -0.0227903 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | -0.0225858 |
| REL | v-rel avian reticuloendotheliosis viral oncogene homolog | -0.0224748 |
| ARF1 | ADP-ribosylation factor 1 | -0.022439 |
| VCL | vinculin | -0.0220235 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0219702 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | -0.021945 |
| CCNI | cyclin I | -0.0218011 |
| KDM5A | lysine (K)-specific demethylase 5A | -0.0216476 |
| CBL | Cbl proto-oncogene, E3 ubiquitin protein ligase | -0.021347 |
| NDE1 | nudE neurodevelopment protein 1 | -0.0211238 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0206022 |
| GPATCH2L | G patch domain containing 2-like | -0.0206018 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0205666 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0204596 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0199817 |
