| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Lipoic acid perturbation in NCI-H1792 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Lipoic acid_NCI-H1792 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.197405 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.14923 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.116567 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.108885 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.107031 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | 0.0935413 |
| CD44 | CD44 molecule (Indian blood group) | 0.0862278 |
| NAV2 | neuron navigator 2 | 0.076797 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0725167 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0683671 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0677742 |
| VIM | vimentin | 0.0675181 |
| SMAD3 | SMAD family member 3 | 0.0615342 |
| TGM2 | transglutaminase 2 | 0.0580891 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0569634 |
| LOX | lysyl oxidase | 0.0567991 |
| RHCG | Rh family, C glycoprotein | 0.0528428 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0518258 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0510661 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0504917 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0489019 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0484755 |
| LDHA | lactate dehydrogenase A | 0.0476968 |
| EHBP1 | EH domain binding protein 1 | 0.0465677 |
| VEGFA | vascular endothelial growth factor A | 0.045984 |
| ZC3H12C | zinc finger CCCH-type containing 12C | 0.0453607 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0452854 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | 0.0451965 |
| LOXL2 | lysyl oxidase-like 2 | 0.0451021 |
| NTN4 | netrin 4 | 0.0434966 |
| UTRN | utrophin | 0.0425948 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0415055 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0414085 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | 0.0414043 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.041215 |
| FN1 | fibronectin 1 | 0.0406189 |
| FER | fer (fps/fes related) tyrosine kinase | 0.0403464 |
| RFFL | ring finger and FYVE-like domain containing E3 ubiquitin protein ligase | 0.0400903 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0381011 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0374036 |
| IL1R1 | interleukin 1 receptor, type I | 0.0368894 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0367591 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0361684 |
| MYO10 | myosin X | 0.035742 |
| OPTN | optineurin | 0.035225 |
| ECE1 | endothelin converting enzyme 1 | 0.0347581 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0347255 |
| IRAK2 | interleukin-1 receptor-associated kinase 2 | 0.0347247 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0342389 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.0333477 |
| SYAP1 | synapse associated protein 1 | 0.0328742 |
| B2M | beta-2-microglobulin | 0.0326423 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0324485 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0323888 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0321313 |
| KIAA1217 | KIAA1217 | 0.0312464 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0309904 |
| KSR1 | kinase suppressor of ras 1 | 0.0309377 |
| RAD51B | RAD51 paralog B | 0.0306256 |
| CADPS2 | Ca++-dependent secretion activator 2 | 0.0305311 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0304702 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0302674 |
| FAM107B | family with sequence similarity 107, member B | 0.0300258 |
| HDAC9 | histone deacetylase 9 | 0.0292006 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0285445 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | 0.0285419 |
| CEP250 | centrosomal protein 250kDa | 0.0284713 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0279506 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0272343 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0268982 |
| AHI1 | Abelson helper integration site 1 | 0.0267453 |
| EGFR | epidermal growth factor receptor | 0.0265059 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.0263898 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | 0.0263865 |
| ATF7 | activating transcription factor 7 | 0.0260144 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.02601 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0259657 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.0259467 |
| MIPOL1 | mirror-image polydactyly 1 | 0.0248768 |
| IL6ST | interleukin 6 signal transducer | 0.0247423 |
| ANGPTL4 | angiopoietin-like 4 | 0.0242784 |
| RND3 | Rho family GTPase 3 | 0.0242559 |
| SFTPA2 | surfactant protein A2 | 0.0241832 |
| VEGFC | vascular endothelial growth factor C | 0.0240396 |
| SVIL | supervillin | 0.0239764 |
| SEPTIN9 | septin 9 | 0.0239196 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0234071 |
| LGALS12 | lectin, galactoside-binding, soluble, 12 | 0.0230645 |
| LRRC49 | leucine rich repeat containing 49 | 0.0230057 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0229122 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0228965 |
| KYNU | kynureninase | 0.022823 |
| PODXL | podocalyxin-like | 0.022706 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0226369 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0225758 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0223872 |
| DST | dystonin | 0.02203 |
| WWOX | WW domain containing oxidoreductase | 0.0220257 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0219051 |
| DNMBP | dynamin binding protein | 0.021844 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.266311 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.179059 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.143486 |
| TMSB10 | thymosin beta 10 | -0.135877 |
| GPC6 | glypican 6 | -0.131978 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0783679 |
| CDH13 | cadherin 13 | -0.075731 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0739489 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0728033 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0723332 |
| USP34 | ubiquitin specific peptidase 34 | -0.071979 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0696446 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0695703 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0636321 |
| GLCCI1 | glucocorticoid induced 1 | -0.0619211 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0617154 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0610914 |
| FTL | ferritin, light polypeptide | -0.0599698 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.0583238 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0577671 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0566237 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0565476 |
| DDIT3 | DNA-damage-inducible transcript 3 | -0.0546222 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0534511 |
| NPC1 | Niemann-Pick disease, type C1 | -0.0529155 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0525851 |
| MECOM | MDS1 and EVI1 complex locus | -0.0522773 |
| HMGA2 | high mobility group AT-hook 2 | -0.0514217 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0494602 |
| CDK14 | cyclin-dependent kinase 14 | -0.0490431 |
| PRELID2 | PRELI domain containing 2 | -0.0484886 |
| FAM20C | family with sequence similarity 20, member C | -0.0484806 |
| OGA | O-GlcNAcase | -0.0483467 |
| MTSS1 | metastasis suppressor 1 | -0.0471083 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0442694 |
| ZNF804A | zinc finger protein 804A | -0.0434343 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0426639 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0419196 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0409444 |
| RBM39 | RNA binding motif protein 39 | -0.0405648 |
| MT2A | metallothionein 2A | -0.0404177 |
| ETV6 | ets variant 6 | -0.0396192 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0391919 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0391269 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0376285 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | -0.0373443 |
| IER3 | immediate early response 3 | -0.0369321 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0357801 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0352004 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0346586 |
| OSMR | oncostatin M receptor | -0.0342965 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0340989 |
| NLK | nemo-like kinase | -0.0336034 |
| ITGBL1 | integrin, beta-like 1 (with EGF-like repeat domains) | -0.0335411 |
| HDAC4 | histone deacetylase 4 | -0.0332086 |
| DIAPH2 | diaphanous-related formin 2 | -0.0331464 |
| VCL | vinculin | -0.0330749 |
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) | -0.0329877 |
| NEK7 | NIMA-related kinase 7 | -0.0329654 |
| SETD5 | SET domain containing 5 | -0.032946 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | -0.0325345 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.032405 |
| CUX1 | cut-like homeobox 1 | -0.0322622 |
| MSRB3 | methionine sulfoxide reductase B3 | -0.0322195 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.0321451 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0319701 |
| GNAS | GNAS complex locus | -0.0318552 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0318342 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0314595 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0309816 |
| COL7A1 | collagen, type VII, alpha 1 | -0.0305893 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0305533 |
| CFAP20DC | CFAP20 domain containing | -0.0303908 |
| PTMA | prothymosin, alpha | -0.0303534 |
| COL12A1 | collagen, type XII, alpha 1 | -0.0302953 |
| RBMS1 | RNA binding motif, single stranded interacting protein 1 | -0.030237 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0301093 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0299709 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0293415 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0289963 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0289146 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0288639 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0283711 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.0282112 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.027934 |
| EFCAB13 | EF-hand calcium binding domain 13 | -0.0278411 |
| NRG1 | neuregulin 1 | -0.0277091 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0274742 |
| TMEM263 | transmembrane protein 263 | -0.0272646 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | -0.0270821 |
| NF1 | neurofibromin 1 | -0.0270534 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | -0.0269598 |
| PTGIS | prostaglandin I2 (prostacyclin) synthase | -0.0268669 |
| RPS21 | ribosomal protein S21 | -0.0267532 |
| MMP14 | matrix metallopeptidase 14 (membrane-inserted) | -0.0262632 |
| SSBP2 | single-stranded DNA binding protein 2 | -0.0258303 |
| SOS2 | son of sevenless homolog 2 (Drosophila) | -0.0257592 |
| FOXP1 | forkhead box P1 | -0.0256205 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0255844 |
| STC1 | stanniocalcin 1 | -0.0255471 |
