| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Lipoic acid perturbation in NCI-H2030 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Lipoic acid_NCI-H2030 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FTH1 | ferritin, heavy polypeptide 1 | 0.182564 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.172609 |
| TMSB10 | thymosin beta 10 | 0.120254 |
| PM20D1 | peptidase M20 domain containing 1 | 0.11408 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.105815 |
| VIM | vimentin | 0.0992842 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.096128 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0838823 |
| FTL | ferritin, light polypeptide | 0.0830685 |
| IGF2 | insulin-like growth factor 2 | 0.0820175 |
| SMOC1 | SPARC related modular calcium binding 1 | 0.0799209 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0776797 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0711091 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0641676 |
| CMIP | c-Maf inducing protein | 0.0629535 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.0612764 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0611323 |
| LDHA | lactate dehydrogenase A | 0.0572795 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0528694 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0525884 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0490603 |
| COPA | coatomer protein complex, subunit alpha | 0.0464217 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0454555 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0451757 |
| PCBP2 | poly(rC) binding protein 2 | 0.0441251 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | 0.0439377 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0414708 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0411495 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0411391 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0400997 |
| ATF6 | activating transcription factor 6 | 0.0375624 |
| PFN1 | profilin 1 | 0.037115 |
| CALR | calreticulin | 0.0362151 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0361371 |
| KYNU | kynureninase | 0.0360924 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0359936 |
| PDE10A | phosphodiesterase 10A | 0.0332379 |
| RBM39 | RNA binding motif protein 39 | 0.0324041 |
| AHNAK | AHNAK nucleoprotein | 0.0323634 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0321623 |
| NF1 | neurofibromin 1 | 0.0321379 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0321309 |
| AGO2 | argonaute RISC catalytic component 2 | 0.0318618 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | 0.0314725 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0305781 |
| SPIDR | scaffolding protein involved in DNA repair | 0.0304731 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0302995 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | 0.0300666 |
| MAP4K3 | mitogen-activated protein kinase kinase kinase kinase 3 | 0.0298321 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0298272 |
| CTBP2 | C-terminal binding protein 2 | 0.029599 |
| LARP4B | La ribonucleoprotein domain family, member 4B | 0.0295792 |
| CYTH1 | cytohesin 1 | 0.0289927 |
| VDAC1 | voltage-dependent anion channel 1 | 0.0287838 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0285913 |
| CAMKMT | calmodulin-lysine N-methyltransferase | 0.0279657 |
| USP36 | ubiquitin specific peptidase 36 | 0.0273845 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0273038 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0268519 |
| PCNX4 | pecanex 4 | 0.0265984 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0264877 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.026403 |
| BDP1 | B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB | 0.026326 |
| EGFR | epidermal growth factor receptor | 0.0262991 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.0259728 |
| NEDD4 | neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase | 0.0257982 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.0255779 |
| MYO1E | myosin IE | 0.0250769 |
| PRKCE | protein kinase C, epsilon | 0.0250741 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0249207 |
| FLNB | filamin B, beta | 0.0248905 |
| FGA | fibrinogen alpha chain | 0.0248535 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0248382 |
| STRN3 | striatin, calmodulin binding protein 3 | 0.024815 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0246494 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0243414 |
| NRG1 | neuregulin 1 | 0.0243184 |
| RPTOR | regulatory associated protein of MTOR, complex 1 | 0.024259 |
| INTS6 | integrator complex subunit 6 | 0.0240239 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0239693 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0239596 |
| EXOC6B | exocyst complex component 6B | 0.0239024 |
| HLA-A | major histocompatibility complex, class I, A | 0.0238785 |
| H1-0 | H1.0 linker histone | 0.0237938 |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) | 0.0237924 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.0237589 |
| UBR3 | ubiquitin protein ligase E3 component n-recognin 3 (putative) | 0.0235901 |
| HYOU1 | hypoxia up-regulated 1 | 0.0232747 |
| RBM5 | RNA binding motif protein 5 | 0.023172 |
| EYA2 | EYA transcriptional coactivator and phosphatase 2 | 0.0231629 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0229257 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0229215 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0226346 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0226115 |
| USP53 | ubiquitin specific peptidase 53 | 0.0225444 |
| HMGA2 | high mobility group AT-hook 2 | 0.0225432 |
| GLG1 | golgi glycoprotein 1 | 0.0224856 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 | 0.0224139 |
| CABIN1 | calcineurin binding protein 1 | 0.0223762 |
| RBM6 | RNA binding motif protein 6 | 0.022329 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GRAMD1B | GRAM domain containing 1B | -0.169609 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.135118 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.118301 |
| RPS2 | ribosomal protein S2 | -0.118138 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.112119 |
| TXNRD1 | thioredoxin reductase 1 | -0.108656 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0943251 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.089275 |
| PTMA | prothymosin, alpha | -0.088939 |
| RTN4 | reticulon 4 | -0.0830322 |
| TPM3 | tropomyosin 3 | -0.0769444 |
| PFDN2 | prefoldin subunit 2 | -0.072993 |
| MT2A | metallothionein 2A | -0.0672795 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0649795 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0627211 |
| RPL19 | ribosomal protein L19 | -0.0620089 |
| IER3 | immediate early response 3 | -0.0602571 |
| DENND4A | DENN/MADD domain containing 4A | -0.0600103 |
| HSPA8 | heat shock 70kDa protein 8 | -0.0579638 |
| ASPH | aspartate beta-hydroxylase | -0.0579013 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.055939 |
| RPS12 | ribosomal protein S12 | -0.0531988 |
| RPL4 | ribosomal protein L4 | -0.0529848 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.050321 |
| PTP4A1 | protein tyrosine phosphatase type IVA, member 1 | -0.0495996 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0493668 |
| APP | amyloid beta (A4) precursor protein | -0.0468613 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0464085 |
| YBX3 | Y box binding protein 3 | -0.0457 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.0456255 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0454499 |
| RPS8 | ribosomal protein S8 | -0.044329 |
| RPS25 | ribosomal protein S25 | -0.0434011 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0424228 |
| RPL7 | ribosomal protein L7 | -0.0423936 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0418775 |
| DGKD | diacylglycerol kinase, delta 130kDa | -0.0384335 |
| KIF5B | kinesin family member 5B | -0.0367099 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0362485 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | -0.0358892 |
| MCL1 | myeloid cell leukemia 1 | -0.0358589 |
| RPL3 | ribosomal protein L3 | -0.0355374 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0342774 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | -0.0341801 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0341067 |
| RPS6 | ribosomal protein S6 | -0.0334936 |
| EIF3H | eukaryotic translation initiation factor 3, subunit H | -0.0326216 |
| WDR43 | WD repeat domain 43 | -0.0317706 |
| BCLAF1 | BCL2-associated transcription factor 1 | -0.0315234 |
| S100A6 | S100 calcium binding protein A6 | -0.0310654 |
| CCL2 | chemokine (C-C motif) ligand 2 | -0.030608 |
| ACTG1 | actin gamma 1 | -0.0305155 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.0299535 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | -0.0298213 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | -0.0292132 |
| ZNF292 | zinc finger protein 292 | -0.0292005 |
| ARPP19 | cAMP-regulated phosphoprotein, 19kDa | -0.0289743 |
| DLGAP5 | discs, large (Drosophila) homolog-associated protein 5 | -0.028687 |
| RPS27A | ribosomal protein S27a | -0.0284254 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | -0.0282593 |
| QKI | QKI, KH domain containing, RNA binding | -0.0279009 |
| GOLT1B | golgi transport 1B | -0.0276888 |
| HDAC9 | histone deacetylase 9 | -0.0274569 |
| RPL37A | ribosomal protein L37a | -0.0272692 |
| UPP1 | uridine phosphorylase 1 | -0.0267047 |
| CAMTA1 | calmodulin binding transcription activator 1 | -0.0264186 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | -0.0262665 |
| RPS7 | ribosomal protein S7 | -0.0261738 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0260173 |
| SUB1 | SUB1 homolog (S. cerevisiae) | -0.0259487 |
| RFWD3 | ring finger and WD repeat domain 3 | -0.0257167 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0255435 |
| ARL5B | ADP-ribosylation factor-like 5B | -0.0255264 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0255094 |
| EGR1 | early growth response 1 | -0.0251674 |
| NCAPD2 | non-SMC condensin I complex, subunit D2 | -0.0251581 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | -0.0251189 |
| CBX5 | chromobox homolog 5 | -0.0248179 |
| SQSTM1 | sequestosome 1 | -0.0247938 |
| USP3 | ubiquitin specific peptidase 3 | -0.024368 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.0241411 |
| CCT5 | chaperonin containing TCP1, subunit 5 (epsilon) | -0.0240007 |
| RPL23 | ribosomal protein L23 | -0.0238051 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | -0.0237383 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0237059 |
| NAV3 | neuron navigator 3 | -0.0236705 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | -0.0232152 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0231891 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0231889 |
| SMAD3 | SMAD family member 3 | -0.0229957 |
| RPS18 | ribosomal protein S18 | -0.0229304 |
| TPM4 | tropomyosin 4 | -0.0228246 |
| CFLAR | CASP8 and FADD-like apoptosis regulator | -0.0228016 |
| RSPO3 | R-spondin 3 | -0.0226972 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | -0.0226049 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0223739 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | -0.0223368 |
| CLTC | clathrin, heavy chain (Hc) | -0.0223191 |
| RPL5 | ribosomal protein L5 | -0.0222927 |
| ECT2 | epithelial cell transforming 2 | -0.0220198 |
