| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Lipoic acid perturbation in NCI-H661 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Lipoic acid_NCI-H661 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0645841 |
| ANKRD33B | ankyrin repeat domain 33B | 0.0628211 |
| COL5A2 | collagen, type V, alpha 2 | 0.0546954 |
| NTM | neurotrimin | 0.0464955 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0404846 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0315671 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0307768 |
| DST | dystonin | 0.0289059 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0287635 |
| SLC2A13 | solute carrier family 2 (facilitated glucose transporter), member 13 | 0.0276153 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0269679 |
| BTBD9 | BTB (POZ) domain containing 9 | 0.0263988 |
| CABLES1 | Cdk5 and Abl enzyme substrate 1 | 0.0263054 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0259923 |
| TGFB2 | transforming growth factor, beta 2 | 0.0236051 |
| SERTAD2 | SERTA domain containing 2 | 0.0234402 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0234134 |
| WDFY3 | WD repeat and FYVE domain containing 3 | 0.0232888 |
| INTS6 | integrator complex subunit 6 | 0.0231836 |
| FOXP2 | forkhead box P2 | 0.0221826 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0217322 |
| LRP12 | low density lipoprotein receptor-related protein 12 | 0.021671 |
| SPPL3 | signal peptide peptidase like 3 | 0.0215655 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0213665 |
| CALR | calreticulin | 0.0213213 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0212481 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0212263 |
| VMP1 | vacuole membrane protein 1 | 0.0209338 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0206017 |
| TNFRSF19 | tumor necrosis factor receptor superfamily, member 19 | 0.0205833 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0205576 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0204115 |
| KCNJ6 | potassium channel, inwardly rectifying subfamily J, member 6 | 0.0203597 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 0.0202024 |
| OSBPL8 | oxysterol binding protein-like 8 | 0.0198984 |
| PPP2R2D | protein phosphatase 2, regulatory subunit B, delta | 0.0198476 |
| SMCHD1 | structural maintenance of chromosomes flexible hinge domain containing 1 | 0.0198083 |
| SORBS2 | sorbin and SH3 domain containing 2 | 0.0196827 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0196477 |
| UBN2 | ubinuclein 2 | 0.0195114 |
| HMGA2 | high mobility group AT-hook 2 | 0.0194778 |
| USP34 | ubiquitin specific peptidase 34 | 0.0193442 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.019224 |
| RYBP | RING1 and YY1 binding protein | 0.0190458 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0190174 |
| QKI | QKI, KH domain containing, RNA binding | 0.0188532 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.0188109 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | 0.0185513 |
| NSUN6 | NOP2/Sun domain family, member 6 | 0.0183116 |
| MTF2 | metal response element binding transcription factor 2 | 0.0183095 |
| XPO6 | exportin 6 | 0.0181892 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0180535 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | 0.0178895 |
| TENM3 | teneurin transmembrane protein 3 | 0.0178622 |
| CUL4B | cullin 4B | 0.0178343 |
| RAB3GAP2 | RAB3 GTPase activating protein subunit 2 (non-catalytic) | 0.0177793 |
| PER1 | period circadian clock 1 | 0.0177616 |
| EPB41L3 | erythrocyte membrane protein band 4.1-like 3 | 0.0176702 |
| PTEN | phosphatase and tensin homolog | 0.01767 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.017533 |
| PAWR | PRKC, apoptosis, WT1, regulator | 0.0170584 |
| STK38L | serine/threonine kinase 38 like | 0.0170439 |
| CDK12 | cyclin-dependent kinase 12 | 0.0169919 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0169784 |
| ATP2C1 | ATPase, Ca++ transporting, type 2C, member 1 | 0.016978 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0167456 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0166876 |
| ELOVL5 | ELOVL fatty acid elongase 5 | 0.0166674 |
| MAD1L1 | MAD1 mitotic arrest deficient-like 1 (yeast) | 0.0166569 |
| NCKAP1 | NCK-associated protein 1 | 0.0166313 |
| TLE1 | transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) | 0.0165658 |
| CMSS1 | cms1 ribosomal small subunit homolog (yeast) | 0.0165115 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0164804 |
| TFG | TRK-fused gene | 0.0163363 |
| USO1 | USO1 vesicle transport factor | 0.0162752 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0161873 |
| RPE | ribulose-5-phosphate-3-epimerase | 0.0161852 |
| CELF2 | CUGBP, Elav-like family member 2 | 0.015999 |
| CSRNP3 | cysteine-serine-rich nuclear protein 3 | 0.0159985 |
| CPNE8 | copine VIII | 0.0159418 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0159178 |
| RNF145 | ring finger protein 145 | 0.0158187 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | 0.0157834 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0157803 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0156143 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0154557 |
| SETD2 | SET domain containing 2 | 0.0153542 |
| DAG1 | dystroglycan 1 (dystrophin-associated glycoprotein 1) | 0.0151234 |
| ATP9B | ATPase, class II, type 9B | 0.0151223 |
| DHX8 | DEAH (Asp-Glu-Ala-His) box polypeptide 8 | 0.0149756 |
| PTBP2 | polypyrimidine tract binding protein 2 | 0.0148915 |
| THBS1 | thrombospondin 1 | 0.0147931 |
| APBA1 | amyloid beta (A4) precursor protein-binding, family A, member 1 | 0.0147163 |
| FMR1 | fragile X mental retardation 1 | 0.0146993 |
| FIGN | fidgetin | 0.0146617 |
| ATP5F1B | ATP synthase F1 subunit beta | 0.0146482 |
| PAG1 | phosphoprotein membrane anchor with glycosphingolipid microdomains 1 | 0.0145589 |
| WASL | Wiskott-Aldrich syndrome-like | 0.0145075 |
| TUFT1 | tuftelin 1 | 0.0144908 |
| RLIM | ring finger protein, LIM domain interacting | 0.0143495 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | -0.23333 |
| COL11A1 | collagen, type XI, alpha 1 | -0.199633 |
| CADM2 | cell adhesion molecule 2 | -0.1854 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.155292 |
| PCLO | piccolo presynaptic cytomatrix protein | -0.127138 |
| CTNNA3 | catenin (cadherin-associated protein), alpha 3 | -0.126373 |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) | -0.123084 |
| ADGRV1 | adhesion G protein-coupled receptor V1 | -0.109938 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | -0.109256 |
| GPC3 | glypican 3 | -0.107112 |
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | -0.0972143 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | -0.0908113 |
| VIM | vimentin | -0.0898452 |
| PHIP | pleckstrin homology domain interacting protein | -0.0790805 |
| PCDH9 | protocadherin 9 | -0.0727321 |
| PTMA | prothymosin, alpha | -0.0655091 |
| COL1A2 | collagen, type I, alpha 2 | -0.0615543 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0597088 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0576353 |
| CSMD3 | CUB and Sushi multiple domains 3 | -0.0573067 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.0562411 |
| NHSL1 | NHS-like 1 | -0.0561373 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.053745 |
| NPAS3 | neuronal PAS domain protein 3 | -0.0510789 |
| PARD3B | par-3 family cell polarity regulator beta | -0.0488445 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0471704 |
| PGK1 | phosphoglycerate kinase 1 | -0.0438743 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0430682 |
| NEBL | nebulette | -0.0430223 |
| ADGRL3 | adhesion G protein-coupled receptor L3 | -0.0429967 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0426766 |
| DARS1 | aspartyl-tRNA synthetase 1 | -0.037622 |
| ACTG1 | actin gamma 1 | -0.0370644 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0369507 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0366164 |
| PRKD1 | protein kinase D1 | -0.0358755 |
| ARHGAP15 | Rho GTPase activating protein 15 | -0.0354496 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0353415 |
| STAG2 | stromal antigen 2 | -0.0349652 |
| RPS8 | ribosomal protein S8 | -0.0343187 |
| HS6ST2 | heparan sulfate 6-O-sulfotransferase 2 | -0.0340425 |
| TTC28 | tetratricopeptide repeat domain 28 | -0.0339948 |
| TMSB10 | thymosin beta 10 | -0.0339142 |
| BMPR1A | bone morphogenetic protein receptor, type IA | -0.0336922 |
| COL3A1 | collagen, type III, alpha 1 | -0.0333674 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0333092 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.0331559 |
| NRXN1 | neurexin 1 | -0.0330819 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.0323047 |
| RPS6 | ribosomal protein S6 | -0.0316281 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0314681 |
| COLGALT2 | collagen beta(1-O)galactosyltransferase 2 | -0.0311733 |
| GNAS | GNAS complex locus | -0.0306518 |
| FST | follistatin | -0.030521 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0301748 |
| SEMA3E | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E | -0.0301042 |
| JMJD1C | jumonji domain containing 1C | -0.0299454 |
| SLC30A8 | solute carrier family 30 (zinc transporter), member 8 | -0.0296819 |
| NCAM2 | neural cell adhesion molecule 2 | -0.0296733 |
| UTRN | utrophin | -0.0296468 |
| RPLP1 | ribosomal protein, large, P1 | -0.0294319 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0293854 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.0291578 |
| RAI1 | retinoic acid induced 1 | -0.0290175 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0288759 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0284543 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0281892 |
| TMSB4X | thymosin beta 4, X-linked | -0.0281533 |
| RALGAPA1 | Ral GTPase activating protein, alpha subunit 1 (catalytic) | -0.0279877 |
| SEMA3D | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D | -0.0278149 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 | -0.0277882 |
| SOX2 | SRY (sex determining region Y)-box 2 | -0.0276496 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0274446 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0273486 |
| RPS16 | ribosomal protein S16 | -0.0272509 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0269078 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0265523 |
| PLEKHG1 | pleckstrin homology domain containing, family G (with RhoGef domain) member 1 | -0.0265429 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0262776 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0262348 |
| HMCN1 | hemicentin 1 | -0.0260819 |
| MED13L | mediator complex subunit 13-like | -0.0260787 |
| H1-0 | H1.0 linker histone | -0.0256503 |
| KLHL5 | kelch-like family member 5 | -0.0255078 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | -0.0252512 |
| PBX3 | pre-B-cell leukemia homeobox 3 | -0.0252343 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0248162 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0243824 |
| ENO1 | enolase 1, (alpha) | -0.0243771 |
| TNS3 | tensin 3 | -0.0243632 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | -0.0243125 |
| MYL12B | myosin, light chain 12B, regulatory | -0.024237 |
| PCDH7 | protocadherin 7 | -0.0241251 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | -0.0240089 |
| MRPS30 | mitochondrial ribosomal protein S30 | -0.0240024 |
| SMC3 | structural maintenance of chromosomes 3 | -0.0238459 |
| PRPF40A | PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) | -0.0236449 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0236136 |
| SAMD4B | sterile alpha motif domain containing 4B | -0.0234026 |
| NRG1 | neuregulin 1 | -0.0233887 |
