| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Lipoic acid perturbation in PANC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Lipoic acid_PANC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ZFP36 | ZFP36 ring finger protein | 0.128766 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.080118 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0780945 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0756467 |
| AKT2 | v-akt murine thymoma viral oncogene homolog 2 | 0.072538 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0708668 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0684682 |
| RPS12 | ribosomal protein S12 | 0.0653692 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0646155 |
| PCBP2 | poly(rC) binding protein 2 | 0.0627166 |
| ASPH | aspartate beta-hydroxylase | 0.0618075 |
| RPS2 | ribosomal protein S2 | 0.0573884 |
| YBX1 | Y box binding protein 1 | 0.0567541 |
| RPS3 | ribosomal protein S3 | 0.054692 |
| SEPTIN9 | septin 9 | 0.0535829 |
| SAMD4B | sterile alpha motif domain containing 4B | 0.0528697 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0489541 |
| MT2A | metallothionein 2A | 0.0489136 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0488259 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0483689 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0480287 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0456829 |
| BRD2 | bromodomain containing 2 | 0.0437112 |
| JMJD1C | jumonji domain containing 1C | 0.0433997 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0416829 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0413939 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0402044 |
| RPS8 | ribosomal protein S8 | 0.0392838 |
| MSN | moesin | 0.0384968 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0374074 |
| VEGFA | vascular endothelial growth factor A | 0.0370205 |
| TPM3 | tropomyosin 3 | 0.0367901 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0359094 |
| SET | SET nuclear proto-oncogene | 0.0358882 |
| SLK | STE20-like kinase | 0.0351946 |
| LDHA | lactate dehydrogenase A | 0.0347603 |
| CENPF | centromere protein F, 350/400kDa | 0.034385 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0341601 |
| SFPQ | splicing factor proline/glutamine-rich | 0.034048 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0331823 |
| VMP1 | vacuole membrane protein 1 | 0.0331775 |
| EGR1 | early growth response 1 | 0.0331134 |
| FTL | ferritin, light polypeptide | 0.0321569 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0321407 |
| RPL37A | ribosomal protein L37a | 0.0316989 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0312579 |
| B2M | beta-2-microglobulin | 0.0311502 |
| CCDC88A | coiled-coil domain containing 88A | 0.0311023 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0305781 |
| FOSL1 | FOS-like antigen 1 | 0.0303267 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.030214 |
| RTN4 | reticulon 4 | 0.0301149 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0294477 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0290328 |
| ZNF146 | zinc finger protein 146 | 0.0285253 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.028283 |
| PTEN | phosphatase and tensin homolog | 0.0282287 |
| RPS6 | ribosomal protein S6 | 0.0280663 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.027164 |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.0270277 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0269344 |
| RPS4X | ribosomal protein S4, X-linked | 0.0267894 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.026786 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0267645 |
| HDAC9 | histone deacetylase 9 | 0.0265995 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0262049 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0260356 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.026033 |
| TXNRD1 | thioredoxin reductase 1 | 0.0260036 |
| SESN2 | sestrin 2 | 0.0254959 |
| RPS17 | ribosomal protein S17 | 0.0254423 |
| STC2 | stanniocalcin 2 | 0.0253791 |
| NRDC | nardilysin convertase | 0.0253641 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0253188 |
| ERBIN | erbb2 interacting protein | 0.0252993 |
| BAG6 | BCL2-associated athanogene 6 | 0.0250037 |
| ITGAV | integrin, alpha V | 0.0247387 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0245238 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0240942 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0239807 |
| POTEF | POTE ankyrin domain family, member F | 0.0238421 |
| MYADM | myeloid-associated differentiation marker | 0.0237282 |
| UTRN | utrophin | 0.0236418 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0231919 |
| GOLGB1 | golgin B1 | 0.0229556 |
| RPL21 | ribosomal protein L21 | 0.0227143 |
| L1CAM | L1 cell adhesion molecule | 0.0226555 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.022612 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0225449 |
| HNRNPH3 | heterogeneous nuclear ribonucleoprotein H3 (2H9) | 0.0220651 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0219339 |
| OPTN | optineurin | 0.0216967 |
| PTK2 | protein tyrosine kinase 2 | 0.0216842 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0216379 |
| NCKAP1 | NCK-associated protein 1 | 0.0215724 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0215149 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0212711 |
| RPL9 | ribosomal protein L9 | 0.0211178 |
| MAP3K10 | mitogen-activated protein kinase kinase kinase 10 | 0.0210457 |
| RPL3 | ribosomal protein L3 | 0.0209194 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.201877 |
| AHNAK | AHNAK nucleoprotein | -0.200429 |
| RPS16 | ribosomal protein S16 | -0.175335 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.148044 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.111648 |
| TMSB10 | thymosin beta 10 | -0.0950368 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0928695 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0925323 |
| ACTN4 | actinin, alpha 4 | -0.0852177 |
| PTMA | prothymosin, alpha | -0.0810769 |
| CD44 | CD44 molecule (Indian blood group) | -0.0674562 |
| TMEM123 | transmembrane protein 123 | -0.0653369 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0601508 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.059945 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0594381 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0552415 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0543436 |
| PGK1 | phosphoglycerate kinase 1 | -0.0519667 |
| CANX | calnexin | -0.0516285 |
| PSMC4 | proteasome (prosome, macropain) 26S subunit, ATPase, 4 | -0.0478848 |
| ACTG1 | actin gamma 1 | -0.0435178 |
| EGFR | epidermal growth factor receptor | -0.0403296 |
| ATG7 | autophagy related 7 | -0.0393504 |
| RPS24 | ribosomal protein S24 | -0.0378786 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.037763 |
| MORF4L2 | mortality factor 4 like 2 | -0.0370964 |
| S100A6 | S100 calcium binding protein A6 | -0.0368209 |
| RPL4 | ribosomal protein L4 | -0.0353613 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | -0.0351478 |
| APP | amyloid beta (A4) precursor protein | -0.0347783 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0341117 |
| MYOF | myoferlin | -0.0340031 |
| EHBP1 | EH domain binding protein 1 | -0.0338863 |
| HDLBP | high density lipoprotein binding protein | -0.0338661 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0331924 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0330762 |
| CALU | calumenin | -0.0326331 |
| CAVIN1 | caveolae associated protein 1 | -0.0317381 |
| JPT2 | Jupiter microtubule associated homolog 2 | -0.0308723 |
| SPAG9 | sperm associated antigen 9 | -0.0303922 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | -0.0301459 |
| TUBB | tubulin, beta class I | -0.0298416 |
| FRMD5 | FERM domain containing 5 | -0.0295435 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0288256 |
| AFAP1 | actin filament associated protein 1 | -0.0279601 |
| WDR45B | WD repeat domain 45B | -0.0270323 |
| RPL27A | ribosomal protein L27a | -0.0266977 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0265309 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.0261791 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0260146 |
| CTSD | cathepsin D | -0.0258062 |
| ZNF217 | zinc finger protein 217 | -0.0257383 |
| DHX32 | DEAH (Asp-Glu-Ala-His) box polypeptide 32 | -0.0256015 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0253138 |
| TRPM7 | transient receptor potential cation channel, subfamily M, member 7 | -0.024519 |
| HSPG2 | heparan sulfate proteoglycan 2 | -0.0244164 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0242873 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0238753 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0236198 |
| TMSB4X | thymosin beta 4, X-linked | -0.0234296 |
| RNF213 | ring finger protein 213 | -0.0234228 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0234195 |
| AHNAK2 | AHNAK nucleoprotein 2 | -0.0233979 |
| FHL2 | four and a half LIM domains 2 | -0.0233462 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0231704 |
| BMAL2 | basic helix-loop-helix ARNT like 2 | -0.0229602 |
| HNRNPL | heterogeneous nuclear ribonucleoprotein L | -0.0224201 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | -0.0220372 |
| H1-0 | H1.0 linker histone | -0.022035 |
| RLF | rearranged L-myc fusion | -0.0218901 |
| ZNF546 | zinc finger protein 546 | -0.0216984 |
| RASAL2 | RAS protein activator like 2 | -0.0216743 |
| S100A10 | S100 calcium binding protein A10 | -0.0216585 |
| BLTP2 | bridge-like lipid transfer protein family member 2 | -0.0213313 |
| RPS5 | ribosomal protein S5 | -0.0213302 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0212828 |
| CD109 | CD109 molecule | -0.0210866 |
| KMT2A | lysine (K)-specific methyltransferase 2A | -0.0210095 |
| EEPD1 | endonuclease/exonuclease/phosphatase family domain containing 1 | -0.0208793 |
| PDE10A | phosphodiesterase 10A | -0.0206477 |
| ARF1 | ADP-ribosylation factor 1 | -0.020536 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0204894 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0202493 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.020237 |
| GNAS | GNAS complex locus | -0.0201819 |
| HMGA2 | high mobility group AT-hook 2 | -0.019971 |
| NF1 | neurofibromin 1 | -0.019837 |
| PRSS23 | protease, serine, 23 | -0.0198335 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0192818 |
| RAB1B | RAB1B, member RAS oncogene family | -0.0192474 |
| NPR2 | natriuretic peptide receptor 2 | -0.0192401 |
| CARD18 | caspase recruitment domain family, member 18 | -0.0192063 |
| SHTN1 | shootin 1 | -0.0186632 |
| HM13 | histocompatibility (minor) 13 | -0.0186607 |
| WASF2 | WAS protein family, member 2 | -0.0186118 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0185783 |
| ENOSF1 | enolase superfamily member 1 | -0.0183378 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | -0.018133 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0181105 |
| ANLN | anillin, actin binding protein | -0.0180572 |
