| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Lipoic acid perturbation in RKO cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Lipoic acid_RKO drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0718874 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.0636521 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0471423 |
| HDAC9 | histone deacetylase 9 | 0.0456855 |
| HMGA2 | high mobility group AT-hook 2 | 0.0382936 |
| TTR | transthyretin | 0.0374257 |
| GOLGA4 | golgin A4 | 0.0348682 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0330447 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0326 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0317113 |
| FLNB | filamin B, beta | 0.0313943 |
| DLC1 | DLC1 Rho GTPase activating protein | 0.0299817 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0288934 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0262295 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0247847 |
| CALD1 | caldesmon 1 | 0.0241408 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0241116 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0237916 |
| SRSF11 | serine/arginine-rich splicing factor 11 | 0.0233422 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0218158 |
| AXL | AXL receptor tyrosine kinase | 0.0217427 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0215742 |
| PCBP2 | poly(rC) binding protein 2 | 0.0215495 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 | 0.0208425 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.020607 |
| ATXN2 | ataxin 2 | 0.0202521 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.0201185 |
| RIC1 | RAB6A GEF complex partner 1 | 0.0199151 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.0196665 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0195061 |
| ATP13A3 | ATPase type 13A3 | 0.0194808 |
| SHANK1 | SH3 and multiple ankyrin repeat domains 1 | 0.0194806 |
| TXNRD1 | thioredoxin reductase 1 | 0.0191103 |
| ETNK1 | ethanolamine kinase 1 | 0.019076 |
| CYP51A1 | cytochrome P450, family 51, subfamily A, polypeptide 1 | 0.0183966 |
| FNBP4 | formin binding protein 4 | 0.0180331 |
| BBX | bobby sox homolog (Drosophila) | 0.0179875 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0179684 |
| TMF1 | TATA element modulatory factor 1 | 0.0178615 |
| SRPK2 | SRSF protein kinase 2 | 0.0177535 |
| XPC | xeroderma pigmentosum, complementation group C | 0.0172007 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0170248 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.016897 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0168727 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.016715 |
| RUNX1 | runt-related transcription factor 1 | 0.0166269 |
| FAM120A | family with sequence similarity 120A | 0.0166074 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.0165388 |
| KDELR1 | KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 | 0.0160604 |
| BCL2L1 | BCL2-like 1 | 0.0159914 |
| TOR1AIP2 | torsin A interacting protein 2 | 0.0159473 |
| MCL1 | myeloid cell leukemia 1 | 0.0157978 |
| SRPK1 | SRSF protein kinase 1 | 0.0156473 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A | 0.015393 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0151234 |
| ARL5B | ADP-ribosylation factor-like 5B | 0.0150043 |
| UBN2 | ubinuclein 2 | 0.0149723 |
| ECPAS | Ecm29 proteasome adaptor and scaffold | 0.0148939 |
| SCFD1 | sec1 family domain containing 1 | 0.0148775 |
| GALNT6 | polypeptide N-acetylgalactosaminyltransferase 6 | 0.0148155 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0147932 |
| YAP1 | Yes-associated protein 1 | 0.0147466 |
| ITSN2 | intersectin 2 | 0.014532 |
| THOC2 | THO complex 2 | 0.0145315 |
| VMP1 | vacuole membrane protein 1 | 0.0143459 |
| ANTXR2 | anthrax toxin receptor 2 | 0.0143102 |
| NF1 | neurofibromin 1 | 0.0142636 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.0142598 |
| RPL3 | ribosomal protein L3 | 0.0142162 |
| TMEM41B | transmembrane protein 41B | 0.0141976 |
| HLA-A | major histocompatibility complex, class I, A | 0.0141794 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0141764 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.014174 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0141511 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0141206 |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.0140926 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | 0.01387 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0137437 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0135544 |
| AP1G1 | adaptor-related protein complex 1, gamma 1 subunit | 0.0135279 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0133845 |
| ZYX | zyxin | 0.013299 |
| DDB2 | damage-specific DNA binding protein 2, 48kDa | 0.0132813 |
| BPTF | bromodomain PHD finger transcription factor | 0.0132692 |
| PHC2 | polyhomeotic homolog 2 (Drosophila) | 0.013218 |
| MAST4 | microtubule associated serine/threonine kinase family member 4 | 0.0132068 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | 0.0131926 |
| PTEN | phosphatase and tensin homolog | 0.0131621 |
| HSD17B12 | hydroxysteroid (17-beta) dehydrogenase 12 | 0.0130259 |
| TRAM1 | translocation associated membrane protein 1 | 0.0129976 |
| SEC24A | SEC24 family member A | 0.0129074 |
| TBC1D23 | TBC1 domain family, member 23 | 0.0129067 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | 0.0128649 |
| KRIT1 | KRIT1, ankyrin repeat containing | 0.0127575 |
| BAZ2B | bromodomain adjacent to zinc finger domain, 2B | 0.0127562 |
| GOLGA2 | golgin A2 | 0.012642 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0125934 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0125732 |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | 0.0125326 |
| ARHGAP10 | Rho GTPase activating protein 10 | 0.012326 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | -0.156607 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.112477 |
| RPL35A | ribosomal protein L35a | -0.0953787 |
| RPLP1 | ribosomal protein, large, P1 | -0.0916662 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0813779 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0799156 |
| AHNAK | AHNAK nucleoprotein | -0.077883 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0757662 |
| ACTG1 | actin gamma 1 | -0.0666232 |
| RPS24 | ribosomal protein S24 | -0.0644415 |
| RPL12 | ribosomal protein L12 | -0.0594874 |
| ZNF438 | zinc finger protein 438 | -0.0590016 |
| ARHGAP22 | Rho GTPase activating protein 22 | -0.058243 |
| RPS6 | ribosomal protein S6 | -0.0579807 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.056121 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0552694 |
| RPS8 | ribosomal protein S8 | -0.0548077 |
| RPL35 | ribosomal protein L35 | -0.054173 |
| RPL23 | ribosomal protein L23 | -0.0540692 |
| RPS21 | ribosomal protein S21 | -0.0523746 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0500238 |
| PTMA | prothymosin, alpha | -0.0491475 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0490948 |
| RPL34 | ribosomal protein L34 | -0.0471282 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0462957 |
| RPLP2 | ribosomal protein, large, P2 | -0.0460851 |
| TMSB10 | thymosin beta 10 | -0.0460042 |
| RPL8 | ribosomal protein L8 | -0.0456407 |
| RPLP0 | ribosomal protein, large, P0 | -0.0453059 |
| C2CD2 | C2 calcium-dependent domain containing 2 | -0.0452451 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0448039 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0436909 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0430911 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0422139 |
| RPL4 | ribosomal protein L4 | -0.0414157 |
| RRBP1 | ribosome binding protein 1 | -0.0406756 |
| RPL19 | ribosomal protein L19 | -0.0404717 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0404178 |
| RPL38 | ribosomal protein L38 | -0.0399487 |
| PGK1 | phosphoglycerate kinase 1 | -0.0392447 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0389935 |
| RPS27A | ribosomal protein S27a | -0.0384562 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0377178 |
| STC1 | stanniocalcin 1 | -0.0371808 |
| RPL13A | ribosomal protein L13a | -0.0364962 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0359759 |
| RPL30 | ribosomal protein L30 | -0.0358075 |
| RPS19 | ribosomal protein S19 | -0.0357365 |
| RPL7A | ribosomal protein L7a | -0.0356365 |
| NAV3 | neuron navigator 3 | -0.0347398 |
| SP100 | SP100 nuclear antigen | -0.0345443 |
| AGO2 | argonaute RISC catalytic component 2 | -0.0343398 |
| PRRC2B | proline-rich coiled-coil 2B | -0.0340191 |
| MTAP | methylthioadenosine phosphorylase | -0.0338956 |
| MATR3 | matrin 3 | -0.0336434 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | -0.0333041 |
| RPL26 | ribosomal protein L26 | -0.0332947 |
| RPS20 | ribosomal protein S20 | -0.0318586 |
| RPS29 | ribosomal protein S29 | -0.0318299 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0317157 |
| RPL7 | ribosomal protein L7 | -0.0307631 |
| RPL31 | ribosomal protein L31 | -0.0299412 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0295639 |
| RPS25 | ribosomal protein S25 | -0.0292173 |
| GNAS | GNAS complex locus | -0.0291512 |
| PKM | pyruvate kinase, muscle | -0.0291044 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0289353 |
| RPS16 | ribosomal protein S16 | -0.0286961 |
| RPL37A | ribosomal protein L37a | -0.0285952 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0283508 |
| SSR3 | signal sequence receptor, gamma (translocon-associated protein gamma) | -0.0283132 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0282429 |
| MT1X | metallothionein 1X | -0.0281921 |
| RPL9 | ribosomal protein L9 | -0.0279843 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | -0.0276129 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.0269107 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0267451 |
| HMGB1 | high mobility group box 1 | -0.0260813 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.025787 |
| ANXA2 | annexin A2 | -0.0255841 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | -0.0255691 |
| EIF3H | eukaryotic translation initiation factor 3, subunit H | -0.0253785 |
| NAV2 | neuron navigator 2 | -0.0251587 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.024867 |
| ENO1 | enolase 1, (alpha) | -0.0246425 |
| RPS15 | ribosomal protein S15 | -0.0243773 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | -0.0243301 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0240606 |
| RTN4 | reticulon 4 | -0.0240119 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0239005 |
| HMGB2 | high mobility group box 2 | -0.0238582 |
| RIGI | RNA sensor RIG-I | -0.0238199 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0234274 |
| ASPH | aspartate beta-hydroxylase | -0.0233103 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | -0.0232853 |
| TPR | translocated promoter region, nuclear basket protein | -0.0232831 |
| RPL10A | ribosomal protein L10a | -0.0231265 |
| RPL28 | ribosomal protein L28 | -0.0231019 |
| S100A2 | S100 calcium binding protein A2 | -0.0230036 |
| RGS4 | regulator of G-protein signaling 4 | -0.0229937 |
