| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Lipoic acid perturbation in SK-MEL-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Lipoic acid_SK-MEL-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| DST | dystonin | 0.0799445 |
| NLGN1 | neuroligin 1 | 0.0786993 |
| RAD51B | RAD51 paralog B | 0.0776603 |
| NRG3 | neuregulin 3 | 0.0650821 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0604642 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0594784 |
| MSN | moesin | 0.0575314 |
| FHIT | fragile histidine triad | 0.0544008 |
| FRMD4A | FERM domain containing 4A | 0.0539737 |
| FMN1 | formin 1 | 0.0508451 |
| HDAC9 | histone deacetylase 9 | 0.0478577 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0473812 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0468519 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | 0.0424581 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0404033 |
| PTK2 | protein tyrosine kinase 2 | 0.0351365 |
| IFI44L | interferon-induced protein 44-like | 0.0335394 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.032437 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0323285 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0320701 |
| SFPQ | splicing factor proline/glutamine-rich | 0.030423 |
| NOTCH2 | notch 2 | 0.0296609 |
| EXOC4 | exocyst complex component 4 | 0.0277767 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0277682 |
| SOX6 | SRY (sex determining region Y)-box 6 | 0.0276802 |
| LAMB1 | laminin, beta 1 | 0.027588 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | 0.0271527 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0261214 |
| CLIP4 | CAP-GLY domain containing linker protein family, member 4 | 0.0260081 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0249744 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0247304 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0242933 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0241927 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0241909 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0240554 |
| PRELID2 | PRELI domain containing 2 | 0.0240539 |
| FRMD5 | FERM domain containing 5 | 0.0239571 |
| EP300 | E1A binding protein p300 | 0.0238871 |
| IFI16 | interferon, gamma-inducible protein 16 | 0.0234072 |
| SUMF1 | sulfatase modifying factor 1 | 0.0225122 |
| JMJD1C | jumonji domain containing 1C | 0.0223167 |
| LRMDA | leucine rich melanocyte differentiation associated | 0.0220237 |
| HDAC4 | histone deacetylase 4 | 0.0214581 |
| COMMD10 | COMM domain containing 10 | 0.0213954 |
| PLSCR1 | phospholipid scramblase 1 | 0.0209089 |
| VEGFA | vascular endothelial growth factor A | 0.0208989 |
| MDGA2 | MAM domain containing glycosylphosphatidylinositol anchor 2 | 0.0200738 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.020023 |
| SAMD9 | sterile alpha motif domain containing 9 | 0.0198726 |
| GATAD2A | GATA zinc finger domain containing 2A | 0.0198712 |
| CCNL1 | cyclin L1 | 0.0196061 |
| SRPK2 | SRSF protein kinase 2 | 0.0194854 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0194442 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0193796 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0193281 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0192508 |
| RO60 | Ro60, Y RNA binding protein | 0.0188988 |
| EHBP1 | EH domain binding protein 1 | 0.0188856 |
| YEATS2 | YEATS domain containing 2 | 0.0187453 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0186317 |
| TPM3 | tropomyosin 3 | 0.0185482 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0185294 |
| HELZ | helicase with zinc finger | 0.018463 |
| CNKSR3 | CNKSR family member 3 | 0.0184413 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0183474 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0181286 |
| GATAD2B | GATA zinc finger domain containing 2B | 0.0179669 |
| RNF144A | ring finger protein 144A | 0.017737 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.0177048 |
| METTL15 | methyltransferase like 15 | 0.0175694 |
| NSUN6 | NOP2/Sun domain family, member 6 | 0.0174879 |
| FN1 | fibronectin 1 | 0.0174879 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0174053 |
| PARP9 | poly (ADP-ribose) polymerase family, member 9 | 0.0172487 |
| FAM219A | family with sequence similarity 219, member A | 0.0172325 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | 0.0171354 |
| TMEM87A | transmembrane protein 87A | 0.0170715 |
| TRA2B | transformer 2 beta homolog (Drosophila) | 0.0170244 |
| RNF213 | ring finger protein 213 | 0.0169642 |
| CTBP2 | C-terminal binding protein 2 | 0.0169258 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.0168521 |
| NDUFA10 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 10, 42kDa | 0.0164555 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0164491 |
| ZFYVE16 | zinc finger, FYVE domain containing 16 | 0.016387 |
| SCAF8 | SR-related CTD-associated factor 8 | 0.0162602 |
| SP100 | SP100 nuclear antigen | 0.0162219 |
| CYTH3 | cytohesin 3 | 0.0161176 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0160096 |
| FAM78B | family with sequence similarity 78, member B | 0.0157473 |
| UBE3A | ubiquitin protein ligase E3A | 0.0156482 |
| MELTF | melanotransferrin | 0.0156424 |
| KIAA1217 | KIAA1217 | 0.0156291 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0155073 |
| ANGPTL4 | angiopoietin-like 4 | 0.0155057 |
| ZNF654 | zinc finger protein 654 | 0.0154882 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0153936 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.015392 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0152899 |
| BPNT2 | 3'(2'), 5'-bisphosphate nucleotidase 2 | 0.01518 |
| WWOX | WW domain containing oxidoreductase | 0.0149452 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.232889 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.168391 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.127509 |
| LSAMP | limbic system-associated membrane protein | -0.124589 |
| FTL | ferritin, light polypeptide | -0.117366 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.115505 |
| PTMA | prothymosin, alpha | -0.0924464 |
| RPL35A | ribosomal protein L35a | -0.0912257 |
| MT2A | metallothionein 2A | -0.0886285 |
| RPLP1 | ribosomal protein, large, P1 | -0.0869418 |
| RPS6 | ribosomal protein S6 | -0.0782118 |
| PMEL | premelanosome protein | -0.0775085 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.077067 |
| RPS3 | ribosomal protein S3 | -0.0761078 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0760573 |
| SQSTM1 | sequestosome 1 | -0.0746675 |
| RPS8 | ribosomal protein S8 | -0.0698434 |
| RACK1 | receptor for activated C kinase 1 | -0.0626942 |
| PGK1 | phosphoglycerate kinase 1 | -0.0621291 |
| TMSB10 | thymosin beta 10 | -0.0591304 |
| RPS16 | ribosomal protein S16 | -0.0575663 |
| IER3 | immediate early response 3 | -0.0574733 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | -0.0556864 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0539983 |
| ACTG1 | actin gamma 1 | -0.0537894 |
| ICAM1 | intercellular adhesion molecule 1 | -0.0512195 |
| RPL31 | ribosomal protein L31 | -0.0509154 |
| RPS23 | ribosomal protein S23 | -0.0504152 |
| VDAC1 | voltage-dependent anion channel 1 | -0.049864 |
| RPL23 | ribosomal protein L23 | -0.0466816 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0461622 |
| LOC112694756 | uncharaterized LOC112694756 | -0.041547 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | -0.0414966 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0414805 |
| ST13 | suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) | -0.0413143 |
| CA8 | carbonic anhydrase VIII | -0.0411055 |
| ANKRD1 | ankyrin repeat domain 1 (cardiac muscle) | -0.0405736 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0400618 |
| CANX | calnexin | -0.0389307 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0388542 |
| HLA-E | major histocompatibility complex, class I, E | -0.0388428 |
| RPL11 | ribosomal protein L11 | -0.0379138 |
| RPL38 | ribosomal protein L38 | -0.0378225 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0371245 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | -0.0369098 |
| RPL12 | ribosomal protein L12 | -0.0367777 |
| GOLGA4 | golgin A4 | -0.0367761 |
| RPLP2 | ribosomal protein, large, P2 | -0.0353726 |
| RPS13 | ribosomal protein S13 | -0.034959 |
| RPL19 | ribosomal protein L19 | -0.034125 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0336706 |
| RPS12 | ribosomal protein S12 | -0.033542 |
| RPL37A | ribosomal protein L37a | -0.0326586 |
| RPL34 | ribosomal protein L34 | -0.031648 |
| APOD | apolipoprotein D | -0.031436 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0310207 |
| RPS29 | ribosomal protein S29 | -0.0309995 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0306813 |
| RPS20 | ribosomal protein S20 | -0.0304992 |
| TPM4 | tropomyosin 4 | -0.0304398 |
| RPL39 | ribosomal protein L39 | -0.0304012 |
| RPS27A | ribosomal protein S27a | -0.0303253 |
| RPL13A | ribosomal protein L13a | -0.0302856 |
| MORF4L2 | mortality factor 4 like 2 | -0.0300799 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -0.0297565 |
| RPL32 | ribosomal protein L32 | -0.0296612 |
| GNAS | GNAS complex locus | -0.029512 |
| TKT | transketolase | -0.0293941 |
| RPL36A | ribosomal protein L36a | -0.0291569 |
| RPL8 | ribosomal protein L8 | -0.028468 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0283552 |
| B2M | beta-2-microglobulin | -0.0282265 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0282044 |
| KAZN | kazrin, periplakin interacting protein | -0.0270675 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0269945 |
| RPS25 | ribosomal protein S25 | -0.0269706 |
| RPS5 | ribosomal protein S5 | -0.0267302 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0266657 |
| RPL37 | ribosomal protein L37 | -0.026477 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.02638 |
| WDR45B | WD repeat domain 45B | -0.0263274 |
| CSDE1 | cold shock domain containing E1, RNA-binding | -0.0261681 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0259753 |
| RPS11 | ribosomal protein S11 | -0.0259208 |
| RPLP0 | ribosomal protein, large, P0 | -0.0257874 |
| RPL5 | ribosomal protein L5 | -0.025696 |
| S100A9 | S100 calcium binding protein A9 | -0.0256888 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.025255 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0250053 |
| RPS24 | ribosomal protein S24 | -0.0248884 |
| CD44 | CD44 molecule (Indian blood group) | -0.024619 |
| COX4I1 | cytochrome c oxidase subunit IV isoform 1 | -0.0244274 |
| TOMM20 | translocase of outer mitochondrial membrane 20 homolog (yeast) | -0.0243937 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0242767 |
| RPL9 | ribosomal protein L9 | -0.02406 |
| ANXA5 | annexin A5 | -0.0238988 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0238143 |
| RPL36 | ribosomal protein L36 | -0.023605 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0235795 |
| TFRC | transferrin receptor | -0.0230121 |
