| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Lipoic acid perturbation in SNU-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Lipoic acid_SNU-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0925273 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.075319 |
| ZNF292 | zinc finger protein 292 | 0.0708232 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.0603856 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0587008 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0539837 |
| QKI | QKI, KH domain containing, RNA binding | 0.049726 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.0485327 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0475571 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0453131 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0415025 |
| NUP58 | nucleoporin 58 | 0.0403302 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0386374 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0381708 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0352682 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0329811 |
| TXNIP | thioredoxin interacting protein | 0.0329051 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0322773 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0312007 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0311682 |
| USP3 | ubiquitin specific peptidase 3 | 0.0306188 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.030251 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0293539 |
| HELZ | helicase with zinc finger | 0.0284581 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0284178 |
| POTEF | POTE ankyrin domain family, member F | 0.0281523 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0278701 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0278462 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0275957 |
| CNOT6L | CCR4-NOT transcription complex, subunit 6-like | 0.0266989 |
| TFG | TRK-fused gene | 0.0263274 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0258152 |
| GOLGA4 | golgin A4 | 0.0256743 |
| RYBP | RING1 and YY1 binding protein | 0.0256371 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0256337 |
| RNMT | RNA (guanine-7-) methyltransferase | 0.0248883 |
| CCNL1 | cyclin L1 | 0.0248559 |
| SRP54 | signal recognition particle 54kDa | 0.0245078 |
| RHOA | ras homolog family member A | 0.0243177 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0242409 |
| NCKAP1 | NCK-associated protein 1 | 0.024221 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | 0.0241525 |
| ZNF148 | zinc finger protein 148 | 0.0241232 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0240836 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0239992 |
| RIOK3 | RIO kinase 3 | 0.0238428 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0235862 |
| PCBP2 | poly(rC) binding protein 2 | 0.023538 |
| RAB18 | RAB18, member RAS oncogene family | 0.022908 |
| HYOU1 | hypoxia up-regulated 1 | 0.0226863 |
| RLF | rearranged L-myc fusion | 0.0223819 |
| PDS5B | PDS5 cohesin associated factor B | 0.0221395 |
| DNAJB11 | DnaJ (Hsp40) homolog, subfamily B, member 11 | 0.0221271 |
| SLTM | SAFB-like, transcription modulator | 0.0221118 |
| ZNF451 | zinc finger protein 451 | 0.0219397 |
| CDC73 | cell division cycle 73 | 0.0216999 |
| ZNF608 | zinc finger protein 608 | 0.0215685 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0211712 |
| EML4 | echinoderm microtubule associated protein like 4 | 0.0211074 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0210504 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.0206121 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0204877 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0204011 |
| ATOSA | atos homolog A | 0.0201954 |
| SNX9 | sorting nexin 9 | 0.0200815 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0200693 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0200555 |
| PLK2 | polo-like kinase 2 | 0.0200551 |
| MON2 | MON2 homolog (S. cerevisiae) | 0.0199472 |
| SLMAP | sarcolemma associated protein | 0.0199292 |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | 0.0198044 |
| FAM162A | family with sequence similarity 162, member A | 0.019771 |
| RHEB | Ras homolog enriched in brain | 0.0197088 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0196286 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.019578 |
| ELOVL5 | ELOVL fatty acid elongase 5 | 0.0195335 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0195086 |
| ECT2 | epithelial cell transforming 2 | 0.0194592 |
| FGD4 | FYVE, RhoGEF and PH domain containing 4 | 0.0194296 |
| RNF145 | ring finger protein 145 | 0.0193589 |
| CYTH3 | cytohesin 3 | 0.0191065 |
| EZR | ezrin | 0.0190984 |
| CRY1 | cryptochrome circadian clock 1 | 0.0190791 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 0.0189333 |
| YAP1 | Yes-associated protein 1 | 0.0188847 |
| RNASE3 | ribonuclease, RNase A family, 3 | 0.018785 |
| TBC1D12 | TBC1 domain family, member 12 | 0.0186702 |
| MED4 | mediator complex subunit 4 | 0.0186206 |
| PPME1 | protein phosphatase methylesterase 1 | 0.0185379 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0185149 |
| PPP1CB | protein phosphatase 1, catalytic subunit, beta isozyme | 0.0184346 |
| CCNY | cyclin Y | 0.0181888 |
| CREB3L2 | cAMP responsive element binding protein 3-like 2 | 0.0181605 |
| KIF5C | kinesin family member 5C | 0.0181473 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0181405 |
| RUSC2 | RUN and SH3 domain containing 2 | 0.0181116 |
| FAM13A | family with sequence similarity 13, member A | 0.0180011 |
| TRA2B | transformer 2 beta homolog (Drosophila) | 0.01798 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0179155 |
| BRD2 | bromodomain containing 2 | 0.0178971 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VCL | vinculin | -0.192065 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.149665 |
| AHNAK | AHNAK nucleoprotein | -0.138939 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | -0.130024 |
| FOXP1 | forkhead box P1 | -0.122887 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | -0.119635 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.110174 |
| CACNB4 | calcium channel, voltage-dependent, beta 4 subunit | -0.107826 |
| NBEA | neurobeachin | -0.102195 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.100065 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0971187 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | -0.094262 |
| PTMA | prothymosin, alpha | -0.0934167 |
| TMSB4X | thymosin beta 4, X-linked | -0.0882729 |
| EGFR | epidermal growth factor receptor | -0.0852783 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0776897 |
| ENOX1 | ecto-NOX disulfide-thiol exchanger 1 | -0.0759465 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0733107 |
| FLNB | filamin B, beta | -0.0702373 |
| ACTG1 | actin gamma 1 | -0.0692868 |
| ADAM10 | ADAM metallopeptidase domain 10 | -0.0658963 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0652142 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0635624 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0625391 |
| CAMKMT | calmodulin-lysine N-methyltransferase | -0.0623155 |
| TNFRSF11B | tumor necrosis factor receptor superfamily, member 11b | -0.0614155 |
| SOX6 | SRY (sex determining region Y)-box 6 | -0.0610247 |
| TTC28 | tetratricopeptide repeat domain 28 | -0.0588037 |
| GLI3 | GLI family zinc finger 3 | -0.0560843 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0550595 |
| SMYD3 | SET and MYND domain containing 3 | -0.05185 |
| EFNA5 | ephrin-A5 | -0.0498101 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0496598 |
| CCND1 | cyclin D1 | -0.0487147 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0466715 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0464274 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0462566 |
| NFIA | nuclear factor I/A | -0.0452968 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0452934 |
| GLI2 | GLI family zinc finger 2 | -0.0449048 |
| RPS6 | ribosomal protein S6 | -0.0427926 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0422488 |
| S100A6 | S100 calcium binding protein A6 | -0.0409852 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0409389 |
| OSMR | oncostatin M receptor | -0.0407809 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0406056 |
| RPL26 | ribosomal protein L26 | -0.0399772 |
| RPLP0 | ribosomal protein, large, P0 | -0.0397663 |
| TXNRD1 | thioredoxin reductase 1 | -0.0397506 |
| DIAPH2 | diaphanous-related formin 2 | -0.0385532 |
| TJP1 | tight junction protein 1 | -0.0385279 |
| RPL35A | ribosomal protein L35a | -0.0379253 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0374145 |
| BMP10 | bone morphogenetic protein 10 | -0.0371954 |
| MYO5C | myosin VC | -0.0362884 |
| PYGB | phosphorylase, glycogen; brain | -0.0360879 |
| RPL11 | ribosomal protein L11 | -0.0359302 |
| RPS24 | ribosomal protein S24 | -0.0352166 |
| KLF3 | Kruppel-like factor 3 (basic) | -0.0349707 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0348506 |
| GCNT1 | glucosaminyl (N-acetyl) transferase 1, core 2 | -0.0347075 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.034654 |
| FHIT | fragile histidine triad | -0.0343768 |
| NAV2 | neuron navigator 2 | -0.0341707 |
| EHBP1 | EH domain binding protein 1 | -0.0338004 |
| GSE1 | Gse1 coiled-coil protein | -0.0337439 |
| ZNF438 | zinc finger protein 438 | -0.0337281 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0333895 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0332522 |
| RPS13 | ribosomal protein S13 | -0.033023 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0327539 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0319173 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | -0.0317935 |
| LOXL3 | lysyl oxidase-like 3 | -0.0317834 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.0310981 |
| PRELID2 | PRELI domain containing 2 | -0.0309645 |
| CUX1 | cut-like homeobox 1 | -0.0304184 |
| RPS8 | ribosomal protein S8 | -0.030326 |
| RPL4 | ribosomal protein L4 | -0.030271 |
| PRUNE2 | prune homolog 2 (Drosophila) | -0.0298216 |
| ZNF217 | zinc finger protein 217 | -0.0295621 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0295308 |
| RPL34 | ribosomal protein L34 | -0.0292568 |
| NF1 | neurofibromin 1 | -0.0291321 |
| CYB5B | cytochrome b5 type B (outer mitochondrial membrane) | -0.029045 |
| RPL12 | ribosomal protein L12 | -0.0289652 |
| CENPE | centromere protein E, 312kDa | -0.0289541 |
| RPLP2 | ribosomal protein, large, P2 | -0.0289128 |
| RPL9 | ribosomal protein L9 | -0.0288024 |
| FHAD1 | forkhead-associated (FHA) phosphopeptide binding domain 1 | -0.0287187 |
| SLC1A3 | solute carrier family 1 (glial high affinity glutamate transporter), member 3 | -0.0285703 |
| TMEM65 | transmembrane protein 65 | -0.0282772 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0282704 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0282694 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0280943 |
| TRERF1 | transcriptional regulating factor 1 | -0.0278849 |
| RIGI | RNA sensor RIG-I | -0.0278056 |
| DENND1A | DENN/MADD domain containing 1A | -0.0277728 |
| RAD51B | RAD51 paralog B | -0.0277475 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0274193 |
