| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Lipoic acid perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Lipoic acid_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.139274 |
| HDAC9 | histone deacetylase 9 | 0.118547 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.110868 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.106862 |
| FN1 | fibronectin 1 | 0.0984026 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0938325 |
| INTS6 | integrator complex subunit 6 | 0.07785 |
| CADM1 | cell adhesion molecule 1 | 0.0738126 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0700391 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.0696536 |
| LDHA | lactate dehydrogenase A | 0.068377 |
| PCBP2 | poly(rC) binding protein 2 | 0.0660919 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0618193 |
| SFTPA2 | surfactant protein A2 | 0.0606163 |
| SQSTM1 | sequestosome 1 | 0.0605133 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0602972 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0602326 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0572798 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0572048 |
| SPAG9 | sperm associated antigen 9 | 0.0556907 |
| ADM | adrenomedullin | 0.0542308 |
| CANX | calnexin | 0.0541006 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0529131 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0501369 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0499336 |
| IARS1 | isoleucyl-tRNA synthetase 1 | 0.0483463 |
| OPTN | optineurin | 0.048026 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0471717 |
| MYOF | myoferlin | 0.0470319 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0466999 |
| BRD2 | bromodomain containing 2 | 0.0458144 |
| RND3 | Rho family GTPase 3 | 0.0457387 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0449921 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0440511 |
| FMNL2 | formin-like 2 | 0.0428402 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0424515 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0418556 |
| GOLGB1 | golgin B1 | 0.0416016 |
| RBCK1 | RanBP-type and C3HC4-type zinc finger containing 1 | 0.0414846 |
| DUSP10 | dual specificity phosphatase 10 | 0.0407068 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0397009 |
| AHR | aryl hydrocarbon receptor | 0.0385059 |
| HELZ | helicase with zinc finger | 0.0380091 |
| DDIT3 | DNA-damage-inducible transcript 3 | 0.0379632 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0376617 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0369389 |
| FRMPD4 | FERM and PDZ domain containing 4 | 0.0367553 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0363017 |
| FOXO3 | forkhead box O3 | 0.0359216 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.0351647 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.035096 |
| AFF3 | AF4/FMR2 family, member 3 | 0.0350503 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0350404 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0341536 |
| RYBP | RING1 and YY1 binding protein | 0.0339365 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0339303 |
| EGFR | epidermal growth factor receptor | 0.0337813 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0333611 |
| UBAP2 | ubiquitin associated protein 2 | 0.0329585 |
| VEGFA | vascular endothelial growth factor A | 0.0329459 |
| LOX | lysyl oxidase | 0.0329134 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.0326953 |
| COL5A1 | collagen, type V, alpha 1 | 0.0316691 |
| OSBPL8 | oxysterol binding protein-like 8 | 0.0315131 |
| HLA-A | major histocompatibility complex, class I, A | 0.0311805 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0310739 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0310025 |
| UBE2B | ubiquitin-conjugating enzyme E2B | 0.0309744 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0305778 |
| FNIP1 | folliculin interacting protein 1 | 0.0305175 |
| HMGA2 | high mobility group AT-hook 2 | 0.0301148 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0299258 |
| MLPH | melanophilin | 0.0295887 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0292359 |
| IRS2 | insulin receptor substrate 2 | 0.0290818 |
| B2M | beta-2-microglobulin | 0.0288935 |
| LCOR | ligand dependent nuclear receptor corepressor | 0.0286404 |
| KYNU | kynureninase | 0.0280964 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0280685 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0280015 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | 0.0278721 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0276348 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | 0.0275585 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0275295 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0272708 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.0271085 |
| USP37 | ubiquitin specific peptidase 37 | 0.0270072 |
| OGA | O-GlcNAcase | 0.0269296 |
| TLE4 | transducin-like enhancer of split 4 | 0.026892 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0267589 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0267448 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0266426 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0264738 |
| CHST15 | carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 | 0.0264204 |
| RPS4X | ribosomal protein S4, X-linked | 0.0263809 |
| SETX | senataxin | 0.0263068 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0262386 |
| YBX1 | Y box binding protein 1 | 0.0261951 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0261801 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0261228 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NAMPT | nicotinamide phosphoribosyltransferase | -0.218297 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.139709 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.112928 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.107565 |
| VIM | vimentin | -0.101734 |
| VCL | vinculin | -0.0940767 |
| PGK1 | phosphoglycerate kinase 1 | -0.0909317 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0881678 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.086488 |
| IER3 | immediate early response 3 | -0.0796751 |
| VCAN | versican | -0.0763526 |
| TPM4 | tropomyosin 4 | -0.0740598 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0729444 |
| PTMA | prothymosin, alpha | -0.0706852 |
| HLA-B | major histocompatibility complex, class I, B | -0.0697995 |
| MT2A | metallothionein 2A | -0.0691419 |
| CENPF | centromere protein F, 350/400kDa | -0.0662891 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0650701 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0629289 |
| MKI67 | marker of proliferation Ki-67 | -0.0610565 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0596857 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0590247 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.058496 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0583663 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0553767 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.0529132 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0525639 |
| FRMD4A | FERM domain containing 4A | -0.0520369 |
| RPS24 | ribosomal protein S24 | -0.0506952 |
| GPC6 | glypican 6 | -0.046547 |
| OSMR | oncostatin M receptor | -0.0434098 |
| KIF4A | kinesin family member 4A | -0.0433896 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0433687 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0431731 |
| THBS1 | thrombospondin 1 | -0.0430268 |
| MX1 | MX dynamin-like GTPase 1 | -0.0426578 |
| GLIS3 | GLIS family zinc finger 3 | -0.042332 |
| RAI14 | retinoic acid induced 14 | -0.042017 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0415045 |
| TMSB10 | thymosin beta 10 | -0.0413899 |
| ACTG1 | actin gamma 1 | -0.0410073 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.0409634 |
| CDCP1 | CUB domain containing protein 1 | -0.0394175 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0389403 |
| TMSB4X | thymosin beta 4, X-linked | -0.038907 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.038693 |
| RPL36A | ribosomal protein L36a | -0.0386442 |
| CD44 | CD44 molecule (Indian blood group) | -0.0384239 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0380643 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.037506 |
| RTN4 | reticulon 4 | -0.0372096 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | -0.0369843 |
| NAV2 | neuron navigator 2 | -0.0364205 |
| ANLN | anillin, actin binding protein | -0.035981 |
| BICC1 | BicC family RNA binding protein 1 | -0.0357127 |
| ENO1 | enolase 1, (alpha) | -0.0354373 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0354189 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0354131 |
| SBF2 | SET binding factor 2 | -0.0352332 |
| ZNF292 | zinc finger protein 292 | -0.0330866 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0326816 |
| KLF6 | Kruppel-like factor 6 | -0.0324053 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0323109 |
| CASK | calcium/calmodulin-dependent serine protein kinase (MAGUK family) | -0.0321104 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0316521 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0314626 |
| RPLP2 | ribosomal protein, large, P2 | -0.0314512 |
| TNIP1 | TNFAIP3 interacting protein 1 | -0.0310894 |
| GNAS | GNAS complex locus | -0.0308058 |
| RPL35A | ribosomal protein L35a | -0.0304364 |
| GRIN2A | glutamate receptor, ionotropic, N-methyl D-aspartate 2A | -0.0301607 |
| PRR11 | proline rich 11 | -0.030115 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0300795 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0299192 |
| SYNJ2 | synaptojanin 2 | -0.0298248 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0293472 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0292646 |
| SYAP1 | synapse associated protein 1 | -0.0284854 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0282724 |
| RPS21 | ribosomal protein S21 | -0.0278851 |
| COL1A1 | collagen, type I, alpha 1 | -0.0276674 |
| SRGN | serglycin | -0.027566 |
| RPL9 | ribosomal protein L9 | -0.0275614 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -0.0274011 |
| DIAPH3 | diaphanous-related formin 3 | -0.0271162 |
| GLIPR1 | GLI pathogenesis-related 1 | -0.0271005 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0270988 |
| TPM1 | tropomyosin 1 (alpha) | -0.0270704 |
| XRN1 | 5'-3' exoribonuclease 1 | -0.0269906 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0266947 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0266619 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | -0.0263632 |
| TMEM41B | transmembrane protein 41B | -0.0262838 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0262359 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.026208 |
| NF1 | neurofibromin 1 | -0.0256262 |
| TUBB | tubulin, beta class I | -0.0256199 |
| RPL37A | ribosomal protein L37a | -0.0255026 |
| YBX3 | Y box binding protein 3 | -0.0250441 |
| SLC22A4 | solute carrier family 22 (organic cation/zwitterion transporter), member 4 | -0.0249671 |
