| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Lipoic acid perturbation in SW 1088 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Lipoic acid_SW 1088 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.226831 |
| COL6A3 | collagen, type VI, alpha 3 | 0.16799 |
| FN1 | fibronectin 1 | 0.091647 |
| CDH13 | cadherin 13 | 0.0719264 |
| EGFR | epidermal growth factor receptor | 0.0626747 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0569257 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0550488 |
| COL5A1 | collagen, type V, alpha 1 | 0.0531872 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0520968 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0517873 |
| LOX | lysyl oxidase | 0.0508513 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0492389 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | 0.0490072 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0479745 |
| KYNU | kynureninase | 0.0456159 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0452115 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.044714 |
| TNS3 | tensin 3 | 0.0435866 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0427351 |
| IL6 | interleukin 6 | 0.0421016 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0417478 |
| INTS6 | integrator complex subunit 6 | 0.0412106 |
| VEGFC | vascular endothelial growth factor C | 0.0403949 |
| FAM13A | family with sequence similarity 13, member A | 0.0386249 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.0381894 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | 0.0372248 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0366408 |
| EXOC4 | exocyst complex component 4 | 0.0365207 |
| HMGA2 | high mobility group AT-hook 2 | 0.0357455 |
| ATXN1 | ataxin 1 | 0.0357272 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0351753 |
| GOLGB1 | golgin B1 | 0.0343923 |
| PRELID2 | PRELI domain containing 2 | 0.0334942 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | 0.0330037 |
| MAP1B | microtubule-associated protein 1B | 0.0328387 |
| SEPTIN9 | septin 9 | 0.0318813 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0315874 |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) | 0.031574 |
| CANX | calnexin | 0.0309606 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.0305909 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0300595 |
| CALD1 | caldesmon 1 | 0.029968 |
| NRXN3 | neurexin 3 | 0.0296119 |
| CADM1 | cell adhesion molecule 1 | 0.0294216 |
| B4GALT1 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 | 0.0286761 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.028185 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.028153 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0279417 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.027021 |
| FNDC3B | fibronectin type III domain containing 3B | 0.026245 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0260725 |
| DNAH11 | dynein, axonemal, heavy chain 11 | 0.0255331 |
| EHBP1 | EH domain binding protein 1 | 0.025517 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.025425 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0252936 |
| COL7A1 | collagen, type VII, alpha 1 | 0.0251905 |
| NABP1 | nucleic acid binding protein 1 | 0.0250487 |
| CRYBG3 | beta-gamma crystallin domain containing 3 | 0.0246706 |
| COPA | coatomer protein complex, subunit alpha | 0.0241154 |
| HDAC9 | histone deacetylase 9 | 0.0240288 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0236955 |
| STK10 | serine/threonine kinase 10 | 0.023661 |
| COG6 | component of oligomeric golgi complex 6 | 0.0234709 |
| FER | fer (fps/fes related) tyrosine kinase | 0.023309 |
| PDGFC | platelet derived growth factor C | 0.0231159 |
| RAI14 | retinoic acid induced 14 | 0.0228765 |
| CDK13 | cyclin-dependent kinase 13 | 0.0228113 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0226558 |
| AHNAK | AHNAK nucleoprotein | 0.0222436 |
| MSN | moesin | 0.0221184 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0220504 |
| DCLK2 | doublecortin-like kinase 2 | 0.0220147 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0219652 |
| NAV3 | neuron navigator 3 | 0.0217785 |
| STC2 | stanniocalcin 2 | 0.0217567 |
| FNIP1 | folliculin interacting protein 1 | 0.0217559 |
| NAV1 | neuron navigator 1 | 0.021739 |
| LOXL2 | lysyl oxidase-like 2 | 0.0216484 |
| TLK1 | tousled-like kinase 1 | 0.0215155 |
| ABLIM3 | actin binding LIM protein family, member 3 | 0.0212611 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 | 0.0211701 |
| ANO6 | anoctamin 6 | 0.021082 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0210699 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0210117 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0209619 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | 0.0208595 |
| LMAN1 | lectin, mannose-binding, 1 | 0.0207284 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0206206 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0204892 |
| DST | dystonin | 0.0204546 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.020427 |
| DNAJB6 | DnaJ (Hsp40) homolog, subfamily B, member 6 | 0.0204212 |
| PDLIM5 | PDZ and LIM domain 5 | 0.020374 |
| NRP1 | neuropilin 1 | 0.0202827 |
| C1D | C1D nuclear receptor corepressor | 0.0202598 |
| CCDC14 | coiled-coil domain containing 14 | 0.02025 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0201853 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0201607 |
| DHRSX | dehydrogenase/reductase (SDR family) X-linked | 0.0201512 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 0.0198603 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.2288 |
| MT2A | metallothionein 2A | -0.217682 |
| B2M | beta-2-microglobulin | -0.139541 |
| PTMA | prothymosin, alpha | -0.11812 |
| HLA-B | major histocompatibility complex, class I, B | -0.11739 |
| TMSB10 | thymosin beta 10 | -0.093191 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0686702 |
| VIM | vimentin | -0.0664403 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0639675 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0595582 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0564608 |
| IGFBP7 | insulin-like growth factor binding protein 7 | -0.0562288 |
| H3-3B | H3.3 histone B | -0.0522758 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0494942 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0493973 |
| ZNF292 | zinc finger protein 292 | -0.047917 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0448709 |
| RPL11 | ribosomal protein L11 | -0.044728 |
| RPL26 | ribosomal protein L26 | -0.0419534 |
| FTL | ferritin, light polypeptide | -0.0410016 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0407414 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0404618 |
| HLA-C | major histocompatibility complex, class I, C | -0.0401638 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0393147 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0390005 |
| TFG | TRK-fused gene | -0.0389299 |
| ANLN | anillin, actin binding protein | -0.0370983 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0367235 |
| MT1X | metallothionein 1X | -0.0355418 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0350325 |
| RPL37 | ribosomal protein L37 | -0.034557 |
| S100A10 | S100 calcium binding protein A10 | -0.0327811 |
| GNAS | GNAS complex locus | -0.0325375 |
| RPL15 | ribosomal protein L15 | -0.0323936 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0321569 |
| RPL19 | ribosomal protein L19 | -0.0318662 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0318483 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0317634 |
| MTPN | myotrophin | -0.0316365 |
| PGK1 | phosphoglycerate kinase 1 | -0.0314798 |
| ARRDC3 | arrestin domain containing 3 | -0.0312598 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0311404 |
| MATR3 | matrin 3 | -0.0310596 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.030872 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.03064 |
| COL1A1 | collagen, type I, alpha 1 | -0.0305573 |
| ADM | adrenomedullin | -0.0301879 |
| RPL34 | ribosomal protein L34 | -0.0300693 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0299682 |
| GOLGA4 | golgin A4 | -0.0297581 |
| CXCL3 | chemokine (C-X-C motif) ligand 3 | -0.0289086 |
| SETD5 | SET domain containing 5 | -0.0287495 |
| DDIT4 | DNA-damage-inducible transcript 4 | -0.0287228 |
| CAVIN1 | caveolae associated protein 1 | -0.0286485 |
| SUB1 | SUB1 homolog (S. cerevisiae) | -0.0284692 |
| WDR45B | WD repeat domain 45B | -0.0280266 |
| RPS23 | ribosomal protein S23 | -0.0270214 |
| RPL23 | ribosomal protein L23 | -0.026878 |
| TMSB4X | thymosin beta 4, X-linked | -0.0268412 |
| COL1A2 | collagen, type I, alpha 2 | -0.0267549 |
| CHCHD2 | coiled-coil-helix-coiled-coil-helix domain containing 2 | -0.0262178 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0249715 |
| TPM4 | tropomyosin 4 | -0.0247813 |
| RPL37A | ribosomal protein L37a | -0.024605 |
| RPLP2 | ribosomal protein, large, P2 | -0.0245834 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.024359 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | -0.024181 |
| MKI67 | marker of proliferation Ki-67 | -0.0241419 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | -0.0240752 |
| VEZT | vezatin, adherens junctions transmembrane protein | -0.0240027 |
| RPS8 | ribosomal protein S8 | -0.0235536 |
| RPL35A | ribosomal protein L35a | -0.0233159 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0231518 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0230961 |
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) | -0.022933 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0229322 |
| PDE10A | phosphodiesterase 10A | -0.0229259 |
| RACK1 | receptor for activated C kinase 1 | -0.0227996 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0227934 |
| OGA | O-GlcNAcase | -0.0227826 |
| RPL32 | ribosomal protein L32 | -0.0225944 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0224929 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0223983 |
| RALA | v-ral simian leukemia viral oncogene homolog A (ras related) | -0.0223604 |
| PKM | pyruvate kinase, muscle | -0.022148 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0219989 |
| RNF24 | ring finger protein 24 | -0.0219612 |
| PPME1 | protein phosphatase methylesterase 1 | -0.0217806 |
| SEC63 | SEC63 homolog (S. cerevisiae) | -0.021694 |
| SUCO | SUN domain containing ossification factor | -0.021556 |
| PTN | pleiotrophin | -0.0215529 |
| EGR1 | early growth response 1 | -0.0215006 |
| MAPK8 | mitogen-activated protein kinase 8 | -0.0213728 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | -0.0212911 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.021104 |
| RPS24 | ribosomal protein S24 | -0.0210893 |
| RPL12 | ribosomal protein L12 | -0.0210125 |
| HMGB2 | high mobility group box 2 | -0.0209797 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0207046 |
| RAI1 | retinoic acid induced 1 | -0.0206499 |
