| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Lipoic acid perturbation in SW 900 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Lipoic acid_SW 900 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0582678 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.052339 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.050512 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0504646 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0462808 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.045617 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0443527 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0439822 |
| ASPH | aspartate beta-hydroxylase | 0.0435422 |
| STC2 | stanniocalcin 2 | 0.0426472 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0419994 |
| EFNA5 | ephrin-A5 | 0.0406639 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0334872 |
| SVIL | supervillin | 0.0332667 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0319406 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0315689 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0297188 |
| INTS6 | integrator complex subunit 6 | 0.0295272 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | 0.0288459 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 0.0286478 |
| EREG | epiregulin | 0.027995 |
| SEPTIN9 | septin 9 | 0.0276132 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | 0.027459 |
| EMP1 | epithelial membrane protein 1 | 0.0273279 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0270823 |
| VEGFA | vascular endothelial growth factor A | 0.0267941 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0267346 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0265631 |
| RAI14 | retinoic acid induced 14 | 0.0264453 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0261926 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0236045 |
| TMF1 | TATA element modulatory factor 1 | 0.0232959 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 0.0232638 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0229407 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0221591 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | 0.0216865 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0216012 |
| PCBP2 | poly(rC) binding protein 2 | 0.0215174 |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A | 0.0212342 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0211697 |
| FAT1 | FAT atypical cadherin 1 | 0.0210226 |
| PAPOLA | poly(A) polymerase alpha | 0.0209911 |
| CAPZA2 | capping protein (actin filament) muscle Z-line, alpha 2 | 0.0206047 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0205382 |
| GPC6 | glypican 6 | 0.0196084 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0195734 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0190676 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0189178 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0188739 |
| NDRG1 | N-myc downstream regulated 1 | 0.0188011 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0185561 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0184981 |
| TPM3 | tropomyosin 3 | 0.0183061 |
| CSGALNACT2 | chondroitin sulfate N-acetylgalactosaminyltransferase 2 | 0.0182389 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0180776 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.0177811 |
| PTK2 | protein tyrosine kinase 2 | 0.0177488 |
| CNIH3 | cornichon family AMPA receptor auxiliary protein 3 | 0.0175952 |
| LRRC23 | leucine rich repeat containing 23 | 0.0173904 |
| ZNRF1 | zinc and ring finger 1, E3 ubiquitin protein ligase | 0.0173868 |
| IL6ST | interleukin 6 signal transducer | 0.0173279 |
| RFX2 | regulatory factor X, 2 (influences HLA class II expression) | 0.017293 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0166354 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0163344 |
| COPA | coatomer protein complex, subunit alpha | 0.0162895 |
| VMP1 | vacuole membrane protein 1 | 0.0161122 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.0160186 |
| FRY | furry homolog (Drosophila) | 0.0158515 |
| TUFT1 | tuftelin 1 | 0.0158127 |
| MXD1 | MAX dimerization protein 1 | 0.0157067 |
| MCL1 | myeloid cell leukemia 1 | 0.0156208 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0155837 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0154239 |
| ARHGAP42 | Rho GTPase activating protein 42 | 0.0153975 |
| RUNX1 | runt-related transcription factor 1 | 0.0153923 |
| POU2F2 | POU class 2 homeobox 2 | 0.0152395 |
| FERMT2 | fermitin family member 2 | 0.0150847 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0150097 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | 0.014958 |
| CADM1 | cell adhesion molecule 1 | 0.0148105 |
| PAG1 | phosphoprotein membrane anchor with glycosphingolipid microdomains 1 | 0.0148093 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0147449 |
| ARF4 | ADP-ribosylation factor 4 | 0.0146166 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0144553 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0143946 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0143766 |
| GPATCH2L | G patch domain containing 2-like | 0.0143085 |
| CCNL1 | cyclin L1 | 0.0142449 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0142414 |
| AGPAT4 | 1-acylglycerol-3-phosphate O-acyltransferase 4 | 0.0141325 |
| RCOR1 | REST corepressor 1 | 0.0141149 |
| AGO2 | argonaute RISC catalytic component 2 | 0.0139283 |
| FAM107B | family with sequence similarity 107, member B | 0.0139085 |
| MYADM | myeloid-associated differentiation marker | 0.0138982 |
| RND3 | Rho family GTPase 3 | 0.0137512 |
| FGF18 | fibroblast growth factor 18 | 0.0137329 |
| PCM1 | pericentriolar material 1 | 0.0136937 |
| IPMK | inositol polyphosphate multikinase | 0.0135962 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0135786 |
| KDM3B | lysine (K)-specific demethylase 3B | 0.0134151 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.284153 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.213962 |
| TMSB10 | thymosin beta 10 | -0.135089 |
| HLA-B | major histocompatibility complex, class I, B | -0.130983 |
| PTMA | prothymosin, alpha | -0.116888 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.113992 |
| FN1 | fibronectin 1 | -0.113159 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.110346 |
| SQSTM1 | sequestosome 1 | -0.110086 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.102538 |
| TMSB4X | thymosin beta 4, X-linked | -0.0929684 |
| S100A6 | S100 calcium binding protein A6 | -0.0906565 |
| ITGA1 | integrin, alpha 1 | -0.086404 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0761203 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0741168 |
| CANX | calnexin | -0.0642046 |
| FTL | ferritin, light polypeptide | -0.0629674 |
| CENPF | centromere protein F, 350/400kDa | -0.0607693 |
| RPL35A | ribosomal protein L35a | -0.0562594 |
| SYT1 | synaptotagmin I | -0.0546264 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0544049 |
| VIM | vimentin | -0.0524156 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0518381 |
| IER3 | immediate early response 3 | -0.0472733 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.046386 |
| KLHL5 | kelch-like family member 5 | -0.0455467 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0442064 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0435077 |
| HLA-A | major histocompatibility complex, class I, A | -0.0417342 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0409572 |
| RPS21 | ribosomal protein S21 | -0.0408069 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0404006 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0400241 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0391881 |
| RBM25 | RNA binding motif protein 25 | -0.0383968 |
| MKI67 | marker of proliferation Ki-67 | -0.0382641 |
| ACTG1 | actin gamma 1 | -0.0381562 |
| RPS24 | ribosomal protein S24 | -0.0379959 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0377408 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0371789 |
| RRBP1 | ribosome binding protein 1 | -0.0368446 |
| RPL38 | ribosomal protein L38 | -0.0366389 |
| PLIN2 | perilipin 2 | -0.03602 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0359095 |
| ETV1 | ets variant 1 | -0.0352369 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0352256 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0351146 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0350107 |
| TPI1 | triosephosphate isomerase 1 | -0.0346852 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0346672 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0344732 |
| GNAS | GNAS complex locus | -0.0342645 |
| S100A10 | S100 calcium binding protein A10 | -0.0335775 |
| UBE2K | ubiquitin-conjugating enzyme E2K | -0.0327595 |
| RNF213 | ring finger protein 213 | -0.0324942 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0322351 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0322102 |
| PGK1 | phosphoglycerate kinase 1 | -0.031764 |
| TMEM156 | transmembrane protein 156 | -0.031252 |
| VCL | vinculin | -0.0310895 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0310428 |
| RPL31 | ribosomal protein L31 | -0.0310341 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0307888 |
| ARF1 | ADP-ribosylation factor 1 | -0.0301868 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0300448 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0293497 |
| MAP1B | microtubule-associated protein 1B | -0.0293393 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0293228 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0286931 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0285625 |
| ENO1 | enolase 1, (alpha) | -0.0282582 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0277682 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0276603 |
| RPLP1 | ribosomal protein, large, P1 | -0.027639 |
| HMGA1 | high mobility group AT-hook 1 | -0.0275748 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0274447 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.0273945 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0273199 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.027042 |
| FAF2 | Fas associated factor family member 2 | -0.0270125 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0267423 |
| CALU | calumenin | -0.0266111 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0266097 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0263319 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0262636 |
| RPL11 | ribosomal protein L11 | -0.0262046 |
| SEPTIN7 | septin 7 | -0.0260946 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.0258573 |
| RPS27A | ribosomal protein S27a | -0.0257985 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0255547 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0252349 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0251756 |
| RPS8 | ribosomal protein S8 | -0.0251283 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0250374 |
| OGA | O-GlcNAcase | -0.0249379 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.024729 |
| RPS29 | ribosomal protein S29 | -0.024629 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0244945 |
| RPL26 | ribosomal protein L26 | -0.0242564 |
| CLTC | clathrin, heavy chain (Hc) | -0.0241531 |
