| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Lipoic acid perturbation in SW1417 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Lipoic acid_SW1417 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.137677 |
| GOLGA4 | golgin A4 | 0.113151 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.107089 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0897142 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.068875 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0687588 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0672748 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0646462 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0640156 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0633478 |
| RBM39 | RNA binding motif protein 39 | 0.0622415 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0598349 |
| FAM3C | family with sequence similarity 3, member C | 0.0591051 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0588013 |
| TMF1 | TATA element modulatory factor 1 | 0.0561777 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0539657 |
| COG5 | component of oligomeric golgi complex 5 | 0.0536889 |
| GOLGB1 | golgin B1 | 0.0527013 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0524111 |
| HM13 | histocompatibility (minor) 13 | 0.051438 |
| SPAG9 | sperm associated antigen 9 | 0.0506731 |
| VMP1 | vacuole membrane protein 1 | 0.0497178 |
| CANX | calnexin | 0.0476176 |
| TOP1 | topoisomerase (DNA) I | 0.047591 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0475258 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | 0.0472677 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0465475 |
| SUCO | SUN domain containing ossification factor | 0.0455566 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0451003 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.0450761 |
| RBM33 | RNA binding motif protein 33 | 0.0450119 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0441219 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0440291 |
| HYOU1 | hypoxia up-regulated 1 | 0.0439421 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | 0.0435364 |
| UBN2 | ubinuclein 2 | 0.0426179 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0424392 |
| MON2 | MON2 homolog (S. cerevisiae) | 0.0411945 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | 0.0394637 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0391558 |
| CREB3L2 | cAMP responsive element binding protein 3-like 2 | 0.0385213 |
| PDIA5 | protein disulfide isomerase family A, member 5 | 0.0383193 |
| NCOA3 | nuclear receptor coactivator 3 | 0.0358335 |
| SEC61A1 | Sec61 alpha 1 subunit (S. cerevisiae) | 0.0352587 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0352492 |
| SIL1 | SIL1 nucleotide exchange factor | 0.035078 |
| EIF2AK3 | eukaryotic translation initiation factor 2-alpha kinase 3 | 0.0349229 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0348955 |
| CTBP2 | C-terminal binding protein 2 | 0.0348834 |
| CLINT1 | clathrin interactor 1 | 0.0345891 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0345701 |
| NKTR | natural killer cell triggering receptor | 0.034544 |
| PTGES2 | prostaglandin E synthase 2 | 0.0342234 |
| WWC1 | WW and C2 domain containing 1 | 0.0340389 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.0339262 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0338786 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0338698 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0336933 |
| JMJD1C | jumonji domain containing 1C | 0.0335115 |
| LRP12 | low density lipoprotein receptor-related protein 12 | 0.0334875 |
| ZNF292 | zinc finger protein 292 | 0.0334307 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0330906 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0322305 |
| TFG | TRK-fused gene | 0.0320512 |
| CADPS2 | Ca++-dependent secretion activator 2 | 0.03204 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0319904 |
| RALGAPB | Ral GTPase activating protein, beta subunit (non-catalytic) | 0.0318769 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0315811 |
| SETD2 | SET domain containing 2 | 0.0315512 |
| MYO1E | myosin IE | 0.0314513 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0311671 |
| SMAD3 | SMAD family member 3 | 0.0310879 |
| BRD2 | bromodomain containing 2 | 0.031034 |
| FTL | ferritin, light polypeptide | 0.030673 |
| AFTPH | aftiphilin | 0.0306188 |
| HERC1 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 | 0.0302489 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.0301403 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0300712 |
| MTMR3 | myotubularin related protein 3 | 0.0299373 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0299138 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0299064 |
| DIAPH1 | diaphanous-related formin 1 | 0.0298217 |
| PTK2 | protein tyrosine kinase 2 | 0.0297089 |
| LRRFIP2 | leucine rich repeat (in FLII) interacting protein 2 | 0.0296122 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.029546 |
| OGA | O-GlcNAcase | 0.0291752 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0291498 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | 0.0290633 |
| COPA | coatomer protein complex, subunit alpha | 0.0290469 |
| SIK3 | SIK family kinase 3 | 0.0290203 |
| FBXO11 | F-box protein 11 | 0.0289949 |
| LRRC1 | leucine rich repeat containing 1 | 0.028954 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | 0.0288079 |
| COPB1 | coatomer protein complex, subunit beta 1 | 0.0287235 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | 0.0286954 |
| SNX13 | sorting nexin 13 | 0.0286188 |
| MAGT1 | magnesium transporter 1 | 0.0282068 |
| XPO1 | exportin 1 | 0.0282027 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0279672 |
| CLTC | clathrin, heavy chain (Hc) | 0.0277445 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MAML2 | mastermind-like 2 (Drosophila) | -0.172161 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.122337 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.11201 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0913634 |
| KRT8 | keratin 8, type II | -0.0864418 |
| KRT18 | keratin 18, type I | -0.0780849 |
| PTMA | prothymosin, alpha | -0.0749567 |
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | -0.0742529 |
| MACC1 | metastasis associated in colon cancer 1 | -0.0739184 |
| EHBP1 | EH domain binding protein 1 | -0.0690443 |
| CCND1 | cyclin D1 | -0.0689632 |
| TMSB10 | thymosin beta 10 | -0.0685117 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | -0.0675847 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0572445 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | -0.0541861 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0514684 |
| RPS21 | ribosomal protein S21 | -0.0508908 |
| EPCAM | epithelial cell adhesion molecule | -0.0505435 |
| MSI2 | musashi RNA-binding protein 2 | -0.0478798 |
| EXOC4 | exocyst complex component 4 | -0.0472095 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0454806 |
| AHNAK | AHNAK nucleoprotein | -0.0433909 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0424769 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0424409 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0405629 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0401031 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0377222 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0370865 |
| RPS24 | ribosomal protein S24 | -0.0370428 |
| EGR1 | early growth response 1 | -0.0367825 |
| CENPF | centromere protein F, 350/400kDa | -0.035059 |
| NFIA | nuclear factor I/A | -0.0350387 |
| TMSB4X | thymosin beta 4, X-linked | -0.0347498 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.034674 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0335043 |
| ACTN4 | actinin, alpha 4 | -0.0334936 |
| CBX3 | chromobox homolog 3 | -0.0331043 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | -0.033045 |
| PGK1 | phosphoglycerate kinase 1 | -0.0329467 |
| ANO1 | anoctamin 1, calcium activated chloride channel | -0.0324442 |
| RPS12 | ribosomal protein S12 | -0.0323545 |
| RNF213 | ring finger protein 213 | -0.0322869 |
| MX2 | MX dynamin-like GTPase 2 | -0.0321878 |
| RPL12 | ribosomal protein L12 | -0.0318141 |
| KCNH8 | potassium channel, voltage gated eag related subfamily H, member 8 | -0.0310252 |
| RPLP1 | ribosomal protein, large, P1 | -0.0308499 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0304856 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.030439 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0300879 |
| CADPS | Ca++-dependent secretion activator | -0.0300639 |
| PLSCR1 | phospholipid scramblase 1 | -0.0299498 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0298799 |
| RPLP0 | ribosomal protein, large, P0 | -0.0297458 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0293329 |
| GNAS | GNAS complex locus | -0.0291482 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | -0.0289823 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0286521 |
| EEPD1 | endonuclease/exonuclease/phosphatase family domain containing 1 | -0.028642 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0285593 |
| FRAS1 | Fraser extracellular matrix complex subunit 1 | -0.027978 |
| TMEM123 | transmembrane protein 123 | -0.0275807 |
| SCG2 | secretogranin II | -0.0275233 |
| TPM4 | tropomyosin 4 | -0.0274602 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0271613 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0270351 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0269693 |
| RPL18 | ribosomal protein L18 | -0.0269248 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0265571 |
| DENND1A | DENN/MADD domain containing 1A | -0.0260812 |
| RHPN2 | rhophilin, Rho GTPase binding protein 2 | -0.0260693 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | -0.0259836 |
| EZR | ezrin | -0.025972 |
| RPS19 | ribosomal protein S19 | -0.025807 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.0256076 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0256066 |
| RIGI | RNA sensor RIG-I | -0.0254961 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | -0.0253172 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0252199 |
| DIAPH2 | diaphanous-related formin 2 | -0.0250578 |
| RPL34 | ribosomal protein L34 | -0.0249056 |
| OXSR1 | oxidative stress responsive 1 | -0.0248214 |
| CMTM7 | CKLF-like MARVEL transmembrane domain containing 7 | -0.0241582 |
| LAMB3 | laminin, beta 3 | -0.0241234 |
| VCL | vinculin | -0.0235197 |
| HMGA2 | high mobility group AT-hook 2 | -0.0235066 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0234502 |
| NUDT4 | nudix (nucleoside diphosphate linked moiety X)-type motif 4 | -0.0231388 |
| TPX2 | TPX2, microtubule-associated | -0.0229266 |
| PERP | PERP, TP53 apoptosis effector | -0.0228666 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0228257 |
| NAV2 | neuron navigator 2 | -0.0227991 |
| PRELID2 | PRELI domain containing 2 | -0.0227683 |
| B2M | beta-2-microglobulin | -0.0225406 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0224636 |
| KRT19 | keratin 19, type I | -0.0224392 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.0224297 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0222395 |
| CNKSR3 | CNKSR family member 3 | -0.021744 |
| XYLT1 | xylosyltransferase I | -0.0213996 |
| NSUN6 | NOP2/Sun domain family, member 6 | -0.0213033 |
