| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Lipoic acid perturbation in SW48 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Lipoic acid_SW48 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HMGA2 | high mobility group AT-hook 2 | 0.0947747 |
| RAD51B | RAD51 paralog B | 0.0695991 |
| LAMA4 | laminin, alpha 4 | 0.0676146 |
| RCOR1 | REST corepressor 1 | 0.0603412 |
| FHIT | fragile histidine triad | 0.0485865 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0460031 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0448352 |
| EGFR | epidermal growth factor receptor | 0.0412353 |
| VCL | vinculin | 0.0410335 |
| ATXN1 | ataxin 1 | 0.0376059 |
| ANXA2 | annexin A2 | 0.037284 |
| CCSER1 | coiled-coil serine-rich protein 1 | 0.0336404 |
| EHBP1 | EH domain binding protein 1 | 0.0331416 |
| LAMB3 | laminin, beta 3 | 0.0315893 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0309014 |
| SLCO1B3-SLCO1B7 | SLCO1B3-SLCO1B7 readthrough | 0.0307073 |
| CDK13 | cyclin-dependent kinase 13 | 0.0306988 |
| VMP1 | vacuole membrane protein 1 | 0.0300054 |
| GPC5 | glypican 5 | 0.0296886 |
| EMP1 | epithelial membrane protein 1 | 0.0280132 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0278845 |
| VTI1A | vesicle transport through interaction with t-SNAREs 1A | 0.0273181 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.0262731 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0260997 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0260243 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0255405 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0242572 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0239847 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0235733 |
| NUP50 | nucleoporin 50kDa | 0.0227822 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | 0.0221554 |
| HDAC4 | histone deacetylase 4 | 0.021322 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0205433 |
| SLCO1B3 | solute carrier organic anion transporter family, member 1B3 | 0.0203969 |
| ABR | active BCR-related | 0.0200377 |
| FHL2 | four and a half LIM domains 2 | 0.0199074 |
| HOMER1 | homer scaffolding protein 1 | 0.0198149 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0198137 |
| CMIP | c-Maf inducing protein | 0.0197084 |
| ITGA6 | integrin, alpha 6 | 0.0196911 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | 0.0196371 |
| PRELID2 | PRELI domain containing 2 | 0.0196261 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0195719 |
| SLC30A10 | solute carrier family 30, member 10 | 0.0195405 |
| EXOC4 | exocyst complex component 4 | 0.0192289 |
| PARD3B | par-3 family cell polarity regulator beta | 0.0189453 |
| SGMS2 | sphingomyelin synthase 2 | 0.0188816 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0187242 |
| ASPH | aspartate beta-hydroxylase | 0.0184512 |
| CD9 | CD9 molecule | 0.0182325 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | 0.0181029 |
| PHF14 | PHD finger protein 14 | 0.0180911 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | 0.0178081 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0178023 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0175985 |
| GPHN | gephyrin | 0.0175778 |
| NF1 | neurofibromin 1 | 0.0174771 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0172734 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0172691 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0170698 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0170584 |
| CREB5 | cAMP responsive element binding protein 5 | 0.0169865 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0169008 |
| CDHR3 | cadherin-related family member 3 | 0.0167394 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | 0.016617 |
| WWOX | WW domain containing oxidoreductase | 0.0166049 |
| LGALS12 | lectin, galactoside-binding, soluble, 12 | 0.0165936 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0164181 |
| FNIP1 | folliculin interacting protein 1 | 0.0164048 |
| GLCCI1 | glucocorticoid induced 1 | 0.0162281 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0161117 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.015851 |
| RRM2 | ribonucleotide reductase M2 | 0.0156654 |
| OSBPL10 | oxysterol binding protein-like 10 | 0.0156609 |
| SPATA13 | spermatogenesis associated 13 | 0.0154892 |
| PRKN | parkin RBR E3 ubiquitin protein ligase | 0.0154694 |
| DST | dystonin | 0.0153143 |
| EFNB2 | ephrin-B2 | 0.0151189 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0149856 |
| CUX1 | cut-like homeobox 1 | 0.0144858 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.0140851 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | 0.014076 |
| EGR1 | early growth response 1 | 0.0140645 |
| UGGT2 | UDP-glucose glycoprotein glucosyltransferase 2 | 0.0140447 |
| GOLGB1 | golgin B1 | 0.0140359 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0139303 |
| UGDH | UDP-glucose 6-dehydrogenase | 0.0139183 |
| BBS9 | Bardet-Biedl syndrome 9 | 0.0138602 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.013368 |
| SEPTIN9 | septin 9 | 0.0133662 |
| SETX | senataxin | 0.0133067 |
| TENM3 | teneurin transmembrane protein 3 | 0.0132586 |
| SMAD3 | SMAD family member 3 | 0.0129574 |
| NHSL1 | NHS-like 1 | 0.0128935 |
| LEMD1 | LEM domain containing 1 | 0.0128853 |
| FRAS1 | Fraser extracellular matrix complex subunit 1 | 0.0128834 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.012775 |
| DENND1A | DENN/MADD domain containing 1A | 0.012674 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0126661 |
| IARS1 | isoleucyl-tRNA synthetase 1 | 0.0126661 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | -0.109522 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.107922 |
| AREG | amphiregulin | -0.0847689 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0760201 |
| RPS6 | ribosomal protein S6 | -0.0740808 |
| LMO7 | LIM domain 7 | -0.0711891 |
| ANXA1 | annexin A1 | -0.066473 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0595483 |
| TMSB10 | thymosin beta 10 | -0.0578309 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0554625 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0549575 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0534076 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.0517543 |
| RPS2 | ribosomal protein S2 | -0.0475815 |
| RPL35A | ribosomal protein L35a | -0.0471142 |
| RPS8 | ribosomal protein S8 | -0.043206 |
| RPL26 | ribosomal protein L26 | -0.0429766 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0416095 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | -0.0414158 |
| ACTG1 | actin gamma 1 | -0.0413153 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0405711 |
| RPS24 | ribosomal protein S24 | -0.039398 |
| RPL11 | ribosomal protein L11 | -0.0392391 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0392027 |
| RPLP1 | ribosomal protein, large, P1 | -0.0389456 |
| RPS12 | ribosomal protein S12 | -0.0386188 |
| RPLP2 | ribosomal protein, large, P2 | -0.0372561 |
| RPL12 | ribosomal protein L12 | -0.0371624 |
| GOLGA4 | golgin A4 | -0.0371337 |
| RPS19 | ribosomal protein S19 | -0.0368498 |
| EREG | epiregulin | -0.0363589 |
| TXNRD1 | thioredoxin reductase 1 | -0.0357056 |
| RPL37A | ribosomal protein L37a | -0.034591 |
| RPLP0 | ribosomal protein, large, P0 | -0.0334022 |
| IER3 | immediate early response 3 | -0.0331936 |
| S100A6 | S100 calcium binding protein A6 | -0.0315874 |
| OXR1 | oxidation resistance 1 | -0.0314421 |
| RPL34 | ribosomal protein L34 | -0.0313743 |
| TOP1 | topoisomerase (DNA) I | -0.0305191 |
| PKM | pyruvate kinase, muscle | -0.0302167 |
| RBM25 | RNA binding motif protein 25 | -0.0300818 |
| RPL9 | ribosomal protein L9 | -0.0299534 |
| RPL19 | ribosomal protein L19 | -0.0297202 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0292809 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.029053 |
| RPL32 | ribosomal protein L32 | -0.0285071 |
| RPS29 | ribosomal protein S29 | -0.0279295 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0274213 |
| BBX | bobby sox homolog (Drosophila) | -0.027102 |
| RPS27A | ribosomal protein S27a | -0.0270294 |
| RPL36 | ribosomal protein L36 | -0.0266243 |
| RPS23 | ribosomal protein S23 | -0.0264497 |
| RPS13 | ribosomal protein S13 | -0.0264171 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0261747 |
| S100A10 | S100 calcium binding protein A10 | -0.0257474 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | -0.0256407 |
| PTBP2 | polypyrimidine tract binding protein 2 | -0.0250495 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | -0.0249377 |
| ITPRID2 | ITPR interacting domain containing 2 | -0.024465 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0243221 |
| RACK1 | receptor for activated C kinase 1 | -0.0243171 |
| RNF145 | ring finger protein 145 | -0.0242853 |
| WAC | WW domain containing adaptor with coiled-coil | -0.024264 |
| RPS21 | ribosomal protein S21 | -0.0241946 |
| RPL7 | ribosomal protein L7 | -0.0238741 |
| RPS25 | ribosomal protein S25 | -0.0236288 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0231565 |
| PLAUR | plasminogen activator, urokinase receptor | -0.023048 |
| RPS3 | ribosomal protein S3 | -0.0230457 |
| RPL5 | ribosomal protein L5 | -0.0226449 |
| RPL8 | ribosomal protein L8 | -0.0224813 |
| NEMF | nuclear export mediator factor | -0.022325 |
| RPS17 | ribosomal protein S17 | -0.0222188 |
| RPL23 | ribosomal protein L23 | -0.0221978 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0218822 |
| RAB6A | RAB6A, member RAS oncogene family | -0.0216456 |
| MT2A | metallothionein 2A | -0.0216323 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | -0.0214724 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.0213221 |
| TNPO1 | transportin 1 | -0.0208571 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0206273 |
| RPL7A | ribosomal protein L7a | -0.0203463 |
| HDAC2 | histone deacetylase 2 | -0.0202901 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | -0.0202761 |
| RPL15 | ribosomal protein L15 | -0.0202161 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | -0.0201997 |
| RPL3 | ribosomal protein L3 | -0.0201733 |
| SEPTIN7 | septin 7 | -0.02001 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0199687 |
| RLF | rearranged L-myc fusion | -0.0197873 |
| RUNX2 | runt-related transcription factor 2 | -0.0197819 |
| KDM6A | lysine (K)-specific demethylase 6A | -0.019554 |
| HSPA8 | heat shock 70kDa protein 8 | -0.0192642 |
| GPBP1 | GC-rich promoter binding protein 1 | -0.0190708 |
| CD36 | CD36 molecule (thrombospondin receptor) | -0.0189888 |
| USP3 | ubiquitin specific peptidase 3 | -0.0189706 |
| CSDE1 | cold shock domain containing E1, RNA-binding | -0.0188881 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0188796 |
| RPL35 | ribosomal protein L35 | -0.0187714 |
| TOP2B | topoisomerase (DNA) II beta 180kDa | -0.0187694 |
