| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Lipoic acid perturbation in SW480 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Lipoic acid_SW480 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NKD1 | naked cuticle homolog 1 (Drosophila) | 0.153969 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | 0.0607696 |
| CDH13 | cadherin 13 | 0.047452 |
| INTS6 | integrator complex subunit 6 | 0.0472091 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0332303 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0274727 |
| RAD51B | RAD51 paralog B | 0.0267365 |
| DST | dystonin | 0.0264773 |
| EXOC4 | exocyst complex component 4 | 0.0253907 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | 0.0246747 |
| SPATA13 | spermatogenesis associated 13 | 0.0233448 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0231221 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0227574 |
| CDK6 | cyclin-dependent kinase 6 | 0.0205471 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | 0.0204039 |
| WWOX | WW domain containing oxidoreductase | 0.0195933 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0185711 |
| FTL | ferritin, light polypeptide | 0.0184539 |
| CUX1 | cut-like homeobox 1 | 0.0170086 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.016722 |
| NTSR1 | neurotensin receptor 1 (high affinity) | 0.0165477 |
| CTDSPL | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like | 0.0164049 |
| ASPH | aspartate beta-hydroxylase | 0.0162719 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0162419 |
| FHIT | fragile histidine triad | 0.0159128 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0157001 |
| VOPP1 | vesicular, overexpressed in cancer, prosurvival protein 1 | 0.0156492 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0154866 |
| SKAP1 | src kinase associated phosphoprotein 1 | 0.0149178 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0147315 |
| FRMD5 | FERM domain containing 5 | 0.0142228 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0139211 |
| GRIK5 | glutamate receptor, ionotropic, kainate 5 | 0.0136974 |
| YAP1 | Yes-associated protein 1 | 0.0134844 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0133971 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0129972 |
| UBAP2 | ubiquitin associated protein 2 | 0.0129142 |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 | 0.012636 |
| SEPTIN9 | septin 9 | 0.0123782 |
| ANO1 | anoctamin 1, calcium activated chloride channel | 0.0123552 |
| PCNX4 | pecanex 4 | 0.0122462 |
| MTCL1 | microtubule crosslinking factor 1 | 0.0122149 |
| RPL35A | ribosomal protein L35a | 0.012171 |
| GATAD2A | GATA zinc finger domain containing 2A | 0.0120937 |
| LRMDA | leucine rich melanocyte differentiation associated | 0.0118673 |
| TRMT11 | tRNA methyltransferase 11 homolog (S. cerevisiae) | 0.0118244 |
| AIG1 | androgen-induced 1 | 0.0117317 |
| H1-4 | H1.4 linker histone, cluster member | 0.0116148 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | 0.0114897 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0112935 |
| MRPS6 | mitochondrial ribosomal protein S6 | 0.0109655 |
| NOTUM | notum pectinacetylesterase homolog (Drosophila) | 0.0109256 |
| IGF2 | insulin-like growth factor 2 | 0.0107983 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.0106327 |
| WDR43 | WD repeat domain 43 | 0.0106218 |
| VKORC1L1 | vitamin K epoxide reductase complex, subunit 1-like 1 | 0.0105946 |
| GSPT1 | G1 to S phase transition 1 | 0.0105237 |
| MBTD1 | mbt domain containing 1 | 0.0102863 |
| AGPAT5 | 1-acylglycerol-3-phosphate O-acyltransferase 5 | 0.0102629 |
| KAT6B | K(lysine) acetyltransferase 6B | 0.0102392 |
| NUDT4 | nudix (nucleoside diphosphate linked moiety X)-type motif 4 | 0.0102183 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0101468 |
| EPC2 | enhancer of polycomb homolog 2 (Drosophila) | 0.0100937 |
| RCOR1 | REST corepressor 1 | 0.0100695 |
| NPAS3 | neuronal PAS domain protein 3 | 0.00998365 |
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | 0.00989912 |
| MTAP | methylthioadenosine phosphorylase | 0.00988234 |
| GOLGB1 | golgin B1 | 0.00964113 |
| EGFR | epidermal growth factor receptor | 0.00937405 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | 0.00937015 |
| NOP56 | NOP56 ribonucleoprotein | 0.00936915 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.00933231 |
| ZNF75D | zinc finger protein 75D | 0.00933219 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.00931284 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.00920807 |
| CNKSR3 | CNKSR family member 3 | 0.00920774 |
| COMMD10 | COMM domain containing 10 | 0.00915345 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.00913266 |
| GLI3 | GLI family zinc finger 3 | 0.00912632 |
| BCL2L1 | BCL2-like 1 | 0.00894338 |
| UBN2 | ubinuclein 2 | 0.00880193 |
| TNNC1 | troponin C type 1 (slow) | 0.00870301 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.00868635 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.00856261 |
| FOXQ1 | forkhead box Q1 | 0.00856105 |
| SCFD2 | sec1 family domain containing 2 | 0.00853297 |
| RBP1 | retinol binding protein 1, cellular | 0.00849486 |
| LARP4B | La ribonucleoprotein domain family, member 4B | 0.00844391 |
| EPHB2 | EPH receptor B2 | 0.00843861 |
| PFN1 | profilin 1 | 0.00843238 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.00843104 |
| HMGA2 | high mobility group AT-hook 2 | 0.00842629 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.00840752 |
| BAG6 | BCL2-associated athanogene 6 | 0.00835886 |
| TGFB1 | transforming growth factor, beta 1 | 0.00834784 |
| AXIN2 | axin 2 | 0.00828832 |
| ATXN7L1 | ataxin 7-like 1 | 0.00809823 |
| PMM2 | phosphomannomutase 2 | 0.00809226 |
| SLC39A11 | solute carrier family 39, member 11 | 0.00804066 |
| ZFHX3 | zinc finger homeobox 3 | 0.00803091 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.132266 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.115288 |
| RPS27A | ribosomal protein S27a | -0.0962151 |
| UBC | ubiquitin C | -0.0892755 |
| AHNAK | AHNAK nucleoprotein | -0.086447 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0799736 |
| ENO1 | enolase 1, (alpha) | -0.0574853 |
| PCBP2 | poly(rC) binding protein 2 | -0.0567074 |
| EZR | ezrin | -0.0558412 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0525923 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0502224 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0463945 |
| PTMA | prothymosin, alpha | -0.0456924 |
| TMSB10 | thymosin beta 10 | -0.0456864 |
| RPL23 | ribosomal protein L23 | -0.0449537 |
| OGA | O-GlcNAcase | -0.0421236 |
| PGK1 | phosphoglycerate kinase 1 | -0.0405929 |
| ANLN | anillin, actin binding protein | -0.040022 |
| JUN | jun proto-oncogene | -0.0396225 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0390786 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0389218 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | -0.0378622 |
| PKM | pyruvate kinase, muscle | -0.0373506 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0361397 |
| ZNF292 | zinc finger protein 292 | -0.0341847 |
| ACTN4 | actinin, alpha 4 | -0.0337268 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | -0.0334917 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0325937 |
| RAD21 | RAD21 homolog (S. pombe) | -0.031883 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0318442 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0312369 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0310182 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0308576 |
| MATR3 | matrin 3 | -0.0306476 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0304272 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.0300337 |
| DIAPH3 | diaphanous-related formin 3 | -0.0291561 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.029074 |
| HMGB2 | high mobility group box 2 | -0.0290011 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.0289722 |
| RPS3 | ribosomal protein S3 | -0.0288558 |
| USP34 | ubiquitin specific peptidase 34 | -0.0287913 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.028707 |
| RPL4 | ribosomal protein L4 | -0.0276339 |
| EMP1 | epithelial membrane protein 1 | -0.0276208 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.0273107 |
| KRT8 | keratin 8, type II | -0.027176 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0266809 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0264106 |
| RPL26 | ribosomal protein L26 | -0.0264049 |
| LMO7 | LIM domain 7 | -0.0259688 |
| RPS24 | ribosomal protein S24 | -0.0257931 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0255615 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | -0.0253313 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | -0.0251432 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | -0.024901 |
| XPO1 | exportin 1 | -0.0247003 |
| PERP | PERP, TP53 apoptosis effector | -0.0246019 |
| RLF | rearranged L-myc fusion | -0.024434 |
| RPLP1 | ribosomal protein, large, P1 | -0.0243871 |
| IFRD1 | interferon-related developmental regulator 1 | -0.0243735 |
| ZNF638 | zinc finger protein 638 | -0.0242413 |
| RBM25 | RNA binding motif protein 25 | -0.0240399 |
| NONO | non-POU domain containing, octamer-binding | -0.0240206 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.0237798 |
| NF1 | neurofibromin 1 | -0.0234329 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0233565 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0232977 |
| VMP1 | vacuole membrane protein 1 | -0.0231705 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0230847 |
| PDE8A | phosphodiesterase 8A | -0.0230241 |
| ACTG1 | actin gamma 1 | -0.0229876 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0229568 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0229497 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0228687 |
| RBM39 | RNA binding motif protein 39 | -0.0228322 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | -0.0227396 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0227162 |
| ETNK1 | ethanolamine kinase 1 | -0.0224587 |
| RPL5 | ribosomal protein L5 | -0.0222828 |
| SET | SET nuclear proto-oncogene | -0.0222734 |
| CANX | calnexin | -0.0220881 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0220264 |
| ARGLU1 | arginine and glutamate rich 1 | -0.02192 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0218771 |
| SERINC3 | serine incorporator 3 | -0.0216167 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0212037 |
| USP9X | ubiquitin specific peptidase 9, X-linked | -0.0211496 |
| SLC1A5 | solute carrier family 1 (neutral amino acid transporter), member 5 | -0.0210758 |
| NFATC3 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 | -0.0207534 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.020751 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0206843 |
| RPS12 | ribosomal protein S12 | -0.0204676 |
| RPLP2 | ribosomal protein, large, P2 | -0.020463 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0201797 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0200898 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | -0.0199682 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.019823 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0198213 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0196863 |
