| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Lipoic acid perturbation in hTERT-HPNE cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Lipoic acid_hTERT-HPNE drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | 0.150709 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.107161 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.100333 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.060595 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0575248 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0490325 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0430814 |
| CD44 | CD44 molecule (Indian blood group) | 0.0367466 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0349404 |
| NAA16 | N(alpha)-acetyltransferase 16, NatA auxiliary subunit | 0.0344078 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | 0.0336467 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0321724 |
| HDAC9 | histone deacetylase 9 | 0.0296829 |
| EGFR | epidermal growth factor receptor | 0.0291882 |
| ASPH | aspartate beta-hydroxylase | 0.0291837 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0281571 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0279076 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0275825 |
| MYO10 | myosin X | 0.027393 |
| INTS6 | integrator complex subunit 6 | 0.0262585 |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) | 0.0259557 |
| GLIS3 | GLIS family zinc finger 3 | 0.0259447 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0252727 |
| AMOTL1 | angiomotin like 1 | 0.0249175 |
| PRELID2 | PRELI domain containing 2 | 0.0243056 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0235622 |
| ADAMTS16 | ADAM metallopeptidase with thrombospondin type 1 motif, 16 | 0.0232999 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.023083 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0229762 |
| GOLGB1 | golgin B1 | 0.0222179 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0212266 |
| RAD51B | RAD51 paralog B | 0.0207856 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0194468 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | 0.0192036 |
| ATM | ATM serine/threonine kinase | 0.0190487 |
| AEBP2 | AE binding protein 2 | 0.0187718 |
| ARHGAP22 | Rho GTPase activating protein 22 | 0.0187624 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0177823 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0177195 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0174577 |
| SH3RF1 | SH3 domain containing ring finger 1 | 0.0174305 |
| DGKI | diacylglycerol kinase, iota | 0.0173956 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.0170653 |
| SMYD3 | SET and MYND domain containing 3 | 0.0168092 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0166651 |
| ATXN1 | ataxin 1 | 0.0165091 |
| NAV2 | neuron navigator 2 | 0.0164846 |
| KIAA1217 | KIAA1217 | 0.0164118 |
| BBS9 | Bardet-Biedl syndrome 9 | 0.0163559 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0161193 |
| STC2 | stanniocalcin 2 | 0.0161161 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.015611 |
| EXOC6B | exocyst complex component 6B | 0.0155334 |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | 0.0154629 |
| JAK1 | Janus kinase 1 | 0.0152281 |
| DNMBP | dynamin binding protein | 0.0150202 |
| DNER | delta/notch-like EGF repeat containing | 0.0145944 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0144828 |
| PHF3 | PHD finger protein 3 | 0.0141478 |
| PCBP3 | poly(rC) binding protein 3 | 0.0137966 |
| PHC2 | polyhomeotic homolog 2 (Drosophila) | 0.0137401 |
| NIBAN1 | niban apoptosis regulator 1 | 0.0137042 |
| TRPC1 | transient receptor potential cation channel, subfamily C, member 1 | 0.0136894 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0136621 |
| COG6 | component of oligomeric golgi complex 6 | 0.0136412 |
| FRMPD4 | FERM and PDZ domain containing 4 | 0.0135889 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0134816 |
| HSPA8 | heat shock 70kDa protein 8 | 0.013473 |
| SH3PXD2A | SH3 and PX domains 2A | 0.0133058 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0132689 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0132456 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0131897 |
| ANK2 | ankyrin 2, neuronal | 0.0131763 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.012966 |
| NDEL1 | nudE neurodevelopment protein 1-like 1 | 0.0126884 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | 0.0126337 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0125772 |
| WNT2B | wingless-type MMTV integration site family, member 2B | 0.012563 |
| NOTCH2 | notch 2 | 0.0123813 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0123643 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0123613 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0123443 |
| ALPK1 | alpha-kinase 1 | 0.0122236 |
| HYOU1 | hypoxia up-regulated 1 | 0.0121136 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | 0.0119214 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0119148 |
| TXNIP | thioredoxin interacting protein | 0.0118281 |
| PLPP3 | phospholipid phosphatase 3 | 0.0118002 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0117639 |
| METTL15 | methyltransferase like 15 | 0.0117064 |
| ADAM32 | ADAM metallopeptidase domain 32 | 0.0114551 |
| LRRC49 | leucine rich repeat containing 49 | 0.0114497 |
| GALK2 | galactokinase 2 | 0.0114108 |
| VGLL3 | vestigial-like family member 3 | 0.0113877 |
| CLIC4 | chloride intracellular channel 4 | 0.0112771 |
| ARHGAP31 | Rho GTPase activating protein 31 | 0.011268 |
| PMM2 | phosphomannomutase 2 | 0.0112369 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0112118 |
| GLRX | glutaredoxin (thioltransferase) | 0.0112063 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0112041 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.17654 |
| COL1A1 | collagen, type I, alpha 1 | -0.165248 |
| INHBA | inhibin, beta A | -0.136198 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.132514 |
| COL1A2 | collagen, type I, alpha 2 | -0.105748 |
| STC1 | stanniocalcin 1 | -0.0979732 |
| COL6A3 | collagen, type VI, alpha 3 | -0.0713033 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0640478 |
| EMP1 | epithelial membrane protein 1 | -0.0558363 |
| COL6A2 | collagen, type VI, alpha 2 | -0.0514595 |
| MMP1 | matrix metallopeptidase 1 | -0.0514415 |
| ADM | adrenomedullin | -0.0498012 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.045758 |
| TMSB10 | thymosin beta 10 | -0.0454826 |
| ATP13A3 | ATPase type 13A3 | -0.0445348 |
| FTL | ferritin, light polypeptide | -0.042562 |
| FAM13A | family with sequence similarity 13, member A | -0.0422765 |
| ADGRB3 | adhesion G protein-coupled receptor B3 | -0.0407783 |
| CAVIN1 | caveolae associated protein 1 | -0.0395252 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0389259 |
| ACTG1 | actin gamma 1 | -0.0387953 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0387456 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0383906 |
| IER3 | immediate early response 3 | -0.0381584 |
| COL3A1 | collagen, type III, alpha 1 | -0.0381183 |
| PTMA | prothymosin, alpha | -0.0378352 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | -0.0362984 |
| TPM4 | tropomyosin 4 | -0.0357867 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0348521 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0348398 |
| CALU | calumenin | -0.0330419 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0328038 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0314678 |
| VCAN | versican | -0.0305538 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.02959 |
| CALD1 | caldesmon 1 | -0.0288571 |
| B2M | beta-2-microglobulin | -0.0272437 |
| GREM1 | gremlin 1, DAN family BMP antagonist | -0.0262178 |
| PRR16 | proline rich 16 | -0.0257057 |
| FSTL1 | follistatin-like 1 | -0.0256458 |
| MED13L | mediator complex subunit 13-like | -0.0242863 |
| HLA-B | major histocompatibility complex, class I, B | -0.023818 |
| POTEF | POTE ankyrin domain family, member F | -0.0236673 |
| ATP8B1 | ATPase, aminophospholipid transporter, class I, type 8B, member 1 | -0.0235877 |
| RPLP1 | ribosomal protein, large, P1 | -0.0235476 |
| CDH13 | cadherin 13 | -0.0233896 |
| NDRG1 | N-myc downstream regulated 1 | -0.0231344 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0230277 |
| INSIG1 | insulin induced gene 1 | -0.0230126 |
| CCND1 | cyclin D1 | -0.0228639 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0227373 |
| USP3 | ubiquitin specific peptidase 3 | -0.0226232 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0222664 |
| S100A6 | S100 calcium binding protein A6 | -0.0221964 |
| AHNAK | AHNAK nucleoprotein | -0.0213047 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | -0.0212813 |
| RLF | rearranged L-myc fusion | -0.0211911 |
| OXR1 | oxidation resistance 1 | -0.0204409 |
| ADAMTS12 | ADAM metallopeptidase with thrombospondin type 1 motif, 12 | -0.0202801 |
| TMSB4X | thymosin beta 4, X-linked | -0.0202591 |
| SPAG9 | sperm associated antigen 9 | -0.0200835 |
| SEPTIN11 | septin 11 | -0.0197975 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0197083 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0196988 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0194865 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0194025 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.019378 |
| PGK1 | phosphoglycerate kinase 1 | -0.0186165 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0184432 |
| PRSS23 | protease, serine, 23 | -0.0182664 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0179766 |
| SLC8A1 | solute carrier family 8 (sodium/calcium exchanger), member 1 | -0.0179313 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0178627 |
| RPL34 | ribosomal protein L34 | -0.017613 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0175108 |
| PRKG1 | protein kinase, cGMP-dependent, type I | -0.0174023 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0173497 |
| DDIT4 | DNA-damage-inducible transcript 4 | -0.0173015 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 | -0.017162 |
| FBN1 | fibrillin 1 | -0.0171162 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0170947 |
| RAI14 | retinoic acid induced 14 | -0.0170366 |
| TNPO1 | transportin 1 | -0.0169926 |
| WDR45B | WD repeat domain 45B | -0.0168199 |
| SEPTIN7 | septin 7 | -0.0167414 |
| PKM | pyruvate kinase, muscle | -0.0164914 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0164752 |
| ARHGAP21 | Rho GTPase activating protein 21 | -0.0163588 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0160331 |
| IGFBP4 | insulin-like growth factor binding protein 4 | -0.0159307 |
| DKK3 | dickkopf WNT signaling pathway inhibitor 3 | -0.0159076 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0159075 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0158754 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | -0.0158307 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | -0.0156584 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0155545 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0155146 |
| PRRX1 | paired related homeobox 1 | -0.0153943 |
| NUP58 | nucleoporin 58 | -0.0153912 |
| JUN | jun proto-oncogene | -0.0153599 |
