Lipoma Gene Set

Dataset DISEASES Text-mining Gene-Disease Association Evidence Scores 2025
Category disease or phenotype associations
Type disease
Description A benign, usually painless, well-circumscribed lipomatous tumor composed of adipose tissue. (Experimental Factor Ontology, EFO_0000759)
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Genes

367 genes co-occuring with the disease Lipoma in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores 2025 dataset.

Symbol Name Standardized Value
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase 3.135
HMGA2 high mobility group AT-hook 2 3.122
CD34 CD34 molecule 3.116
MEN1 multiple endocrine neoplasia I 2.905
CDK4 cyclin-dependent kinase 4 2.76
PLAG1 pleiomorphic adenoma gene 1 2.609
LHFPL6 LHFPL tetraspan subfamily member 6 2.577
LPP LIM domain containing preferred translocation partner in lipoma 2.559
NF1 neurofibromin 1 2.457
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog 2.445
CD99L2 CD99 molecule-like 2 2.434
PTEN phosphatase and tensin homolog 2.433
CD99 CD99 molecule 2.417
CALD1 caldesmon 1 2.321
ANO1 anoctamin 1, calcium activated chloride channel 2.255
TSPAN31 tetraspanin 31 2.221
PECAM1 platelet/endothelial cell adhesion molecule 1 2.177
FUS FUS RNA binding protein 2.174
EWSR1 EWS RNA-binding protein 1 2.173
TP53 tumor protein p53 2.144
NAB2 NGFI-A binding protein 2 (EGR1 binding protein 2) 2.134
SOX10 SRY (sex determining region Y)-box 10 2.127
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced 2.124
CD68 CD68 molecule 2.119
LHFPL5 lipoma HMGIC fusion partner-like 5 2.086
AFP alpha-fetoprotein 2.081
MRTFB myocardin related transcription factor B 2.066
CDKN2A cyclin-dependent kinase inhibitor 2A 2.061
SPRED1 sprouty-related, EVH1 domain containing 1 2.051
SYP synaptophysin 2.043
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5 2.035
KRT7 keratin 7, type II 2.032
ENO2 enolase 2 (gamma, neuronal) 2.001
TSC2 tuberous sclerosis 2 1.992
MTOR mechanistic target of rapamycin (serine/threonine kinase) 1.99
HMGA1 high mobility group AT-hook 1 1.987
BCL2 B-cell CLL/lymphoma 2 1.966
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha 1.96
MNX1 motor neuron and pancreas homeobox 1 1.955
AKT1 v-akt murine thymoma viral oncogene homolog 1 1.949
MYOG myogenin (myogenic factor 4) 1.941
MME membrane metallo-endopeptidase 1.933
LHFPL3 lipoma HMGIC fusion partner-like 3 1.933
SMIM10L1 small integral membrane protein 10 like 1 1.878
NFIB nuclear factor I/B 1.873
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 1.872
PRL prolactin 1.868
CHGA chromogranin A 1.862
CALB2 calbindin 2 1.86
GAST gastrin 1.856
ESR1 estrogen receptor 1 1.851
CRP C-reactive protein, pentraxin-related 1.848
PGR progesterone receptor 1.845
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 1.842
KRT20 keratin 20, type I 1.82
INS insulin 1.816
YEATS4 YEATS domain containing 4 1.8
NF2 neurofibromin 2 (merlin) 1.792
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 1.779
KLLN killin, p53-regulated DNA replication inhibitor 1.772
SMARCB1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 1.771
KRT5 keratin 5, type II 1.76
LHFPL2 lipoma HMGIC fusion partner-like 2 1.75
PRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha 1.749
FOXO1 forkhead box O1 1.745
FLCN folliculin 1.743
PTH parathyroid hormone 1.724
PPARG peroxisome proliferator-activated receptor gamma 1.72
POMC proopiomelanocortin 1.716
ATP12A ATPase, H+/K+ transporting, nongastric, alpha polypeptide 1.715
ATP4A ATPase, H+/K+ exchanging, alpha polypeptide 1.715
TSC1 tuberous sclerosis 1 1.708
BRAF B-Raf proto-oncogene, serine/threonine kinase 1.705
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) 1.689
SSX2 synovial sarcoma, X breakpoint 2 1.674
LHFPL1 lipoma HMGIC fusion partner-like 1 1.671
WT1 Wilms tumor 1 1.653
CPM carboxypeptidase M 1.651
RET ret proto-oncogene 1.634
PAX8 paired box 8 1.634
PPIAL4C peptidylprolyl isomerase A (cyclophilin A)-like 4C 1.622
SSX1 synovial sarcoma, X breakpoint 1 1.621
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 1.614
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma 1.613
BMPR1A bone morphogenetic protein receptor, type IA 1.609
TPRG1 tumor protein p63 regulated 1 1.609
SS18 synovial sarcoma translocation, chromosome 18 1.609
MYOD1 myogenic differentiation 1 1.604
NCAM1 neural cell adhesion molecule 1 1.602
TFE3 transcription factor binding to IGHM enhancer 3 1.601
ZSWIM6 zinc finger, SWIM-type containing 6 1.601
PPIAL4E peptidylprolyl isomerase A (cyclophilin A)-like 4E 1.596
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta 1.587
UCP1 uncoupling protein 1 (mitochondrial, proton carrier) 1.586
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta 1.575
SST somatostatin 1.572
IGF1 insulin-like growth factor 1 (somatomedin C) 1.564
PDPN podoplanin 1.553
PPIAL4G peptidylprolyl isomerase A (cyclophilin A)-like 4G 1.553
ERBB2 erb-b2 receptor tyrosine kinase 2 1.538
PPY pancreatic polypeptide 1.537
ALK anaplastic lymphoma receptor tyrosine kinase 1.531
PAX3 paired box 3 1.527
VANGL1 VANGL planar cell polarity protein 1 1.525
FRS2 fibroblast growth factor receptor substrate 2 1.524
RB1 retinoblastoma 1 1.523
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog 1.518
RASA1 RAS p21 protein activator (GTPase activating protein) 1 1.517
AFAP1 actin filament associated protein 1 1.51
ALB albumin 1.509
GFAP glial fibrillary acidic protein 1.508
PPIAL4A peptidylprolyl isomerase A (cyclophilin A)-like 4A 1.508
DHRS12 dehydrogenase/reductase (SDR family) member 12 1.506
FH fumarate hydratase 1.502
HOOK2 hook microtubule-tethering protein 2 1.502
FGFR1 fibroblast growth factor receptor 1 1.498
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip) 1.49
KANSL1L KAT8 regulatory NSL complex subunit 1-like 1.49
MSH6 mutS homolog 6 1.486
CDC73 cell division cycle 73 1.485
SDHD succinate dehydrogenase complex, subunit D, integral membrane protein 1.484
MUTYH mutY homolog 1.484
KRAS Kirsten rat sarcoma viral oncogene homolog 1.482
ZYX zyxin 1.481
PRAMEF13 PRAME family member 13 1.475
JUND jun D proto-oncogene 1.473
ACR acrosin 1.472
CCND1 cyclin D1 1.467
NTRK1 neurotrophic tyrosine kinase, receptor, type 1 1.466
USP6 ubiquitin specific peptidase 6 1.464
GCG glucagon 1.464
TMC2 transmembrane channel-like 2 1.458
PTPRC protein tyrosine phosphatase, receptor type, C 1.454
BRCA1 breast cancer 1, early onset 1.444
MYC v-myc avian myelocytomatosis viral oncogene homolog 1.439
ZNF444 zinc finger protein 444 1.436
NKX2-1 NK2 homeobox 1 1.425
LEP leptin 1.417
ZDBF2 zinc finger, DBF-type containing 2 1.416
KRT19 keratin 19, type I 1.415
MSH2 mutS homolog 2 1.41
TNFRSF8 tumor necrosis factor receptor superfamily, member 8 1.409
MUC4 mucin 4, cell surface associated 1.395
PRDM10 PR domain containing 10 1.394
NBPF12 neuroblastoma breakpoint family, member 12 1.394
ATRX alpha thalassemia/mental retardation syndrome X-linked 1.393
IGF2 insulin-like growth factor 2 1.392
BRCA2 breast cancer 2, early onset 1.392
STK11 serine/threonine kinase 11 1.389
CDKN2C cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) 1.386
CD1B CD1b molecule 1.373
MLH1 mutL homolog 1 1.371
EGFR epidermal growth factor receptor 1.368
CD1A CD1a molecule 1.368
GOLGA6L9 golgin A6 family-like 9 1.368
CD1E CD1e molecule 1.367
PDGFB platelet-derived growth factor beta polypeptide 1.364
PMS2 PMS2 postmeiotic segregation increased 2 (S. cerevisiae) 1.363
CAMTA1 calmodulin binding transcription activator 1 1.357
HAS2 hyaluronan synthase 2 1.352
PLIN1 perilipin 1 1.35
HRAS Harvey rat sarcoma viral oncogene homolog 1.345
TCHP trichoplein, keratin filament binding 1.342
PLIN2 perilipin 2 1.336
TG thyroglobulin 1.33
CDX2 caudal type homeobox 2 1.327
MITF microphthalmia-associated transcription factor 1.326
SHH sonic hedgehog 1.326
COL1A1 collagen, type I, alpha 1 1.322
ITM2B integral membrane protein 2B 1.319
JUN jun proto-oncogene 1.317
MB myoglobin 1.314
PXDN peroxidasin 1.312
PXDNL peroxidasin-like 1.308
SSX4B synovial sarcoma, X breakpoint 4B 1.305
SMAD4 SMAD family member 4 1.303
GNAS GNAS complex locus 1.302
CELSR1 cadherin, EGF LAG seven-pass G-type receptor 1 1.301
SSX4 synovial sarcoma, X breakpoint 4 1.299
VIP vasoactive intestinal peptide 1.295
KRTAP4-9 keratin associated protein 4-9 1.294
GNRH1 gonadotropin-releasing hormone 1 (luteinizing-releasing hormone) 1.292
PDGFRB platelet-derived growth factor receptor, beta polypeptide 1.291
CD1C CD1c molecule 1.28
IL6 interleukin 6 1.274
GCM2 glial cells missing homolog 2 (Drosophila) 1.268
TGFB1 transforming growth factor, beta 1 1.264
VGLL3 vestigial-like family member 3 1.259
ARMC5 armadillo repeat containing 5 1.257
LZTR1 leucine-zipper-like transcription regulator 1 1.256
GPT glutamic-pyruvate transaminase (alanine aminotransferase) 1.25
KRT8 keratin 8, type II 1.248
CD5 CD5 molecule 1.248
MED12 mediator complex subunit 12 1.247
CD1D CD1d molecule 1.245
CD79A CD79a molecule, immunoglobulin-associated alpha 1.24
MAP2K1 mitogen-activated protein kinase kinase 1 1.238
VANGL2 VANGL planar cell polarity protein 2 1.237
F2 coagulation factor II (thrombin) 1.234
TMC1 transmembrane channel-like 1 1.232
CD163 CD163 molecule 1.23
OR4M2 olfactory receptor, family 4, subfamily M, member 2 1.23
FGF2 fibroblast growth factor 2 (basic) 1.227
AKT3 v-akt murine thymoma viral oncogene homolog 3 1.226
PRICKLE1 prickle homolog 1 (Drosophila) 1.225
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 1.225
C6ORF118 chromosome 6 open reading frame 118 1.222
MYH14 myosin, heavy chain 14, non-muscle 1.222
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 1.222
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha 1.221
ADIPOQ adiponectin, C1Q and collagen domain containing 1.218
PAX7 paired box 7 1.215
CDK11A cyclin-dependent kinase 11A 1.215
CD4 CD4 molecule 1.215
LIPE lipase, hormone-sensitive 1.215
AKT2 v-akt murine thymoma viral oncogene homolog 2 1.213
PCNA proliferating cell nuclear antigen 1.212
FABP4 fatty acid binding protein 4, adipocyte 1.211
CAPSL calcyphosine-like 1.21
SOS1 son of sevenless homolog 1 (Drosophila) 1.209
PIK3C3 phosphatidylinositol 3-kinase, catalytic subunit type 3 1.207
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta) 1.207
ATM ATM serine/threonine kinase 1.205
PRKACB protein kinase, cAMP-dependent, catalytic, beta 1.205
GTF2I general transcription factor IIi 1.2
IGF1R insulin-like growth factor 1 receptor 1.199
SLC35E3 solute carrier family 35, member E3 1.198
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1 1.192
CREB3L1 cAMP responsive element binding protein 3-like 1 1.189
PRKACA protein kinase, cAMP-dependent, catalytic, alpha 1.188
NCOA2 nuclear receptor coactivator 2 1.184
SDHC succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa 1.182
MSRB3 methionine sulfoxide reductase B3 1.18
NKAIN2 Na+/K+ transporting ATPase interacting 2 1.179
VASP vasodilator-stimulated phosphoprotein 1.175
LMNA lamin A/C 1.17
CREB3L2 cAMP responsive element binding protein 3-like 2 1.17
IFNA17 interferon, alpha 17 1.168
IFNA2 interferon, alpha 2 1.167
SOX9 SRY (sex determining region Y)-box 9 1.164
GLI1 GLI family zinc finger 1 1.162
GLMN glomulin, FKBP associated protein 1.161
PTPN11 protein tyrosine phosphatase, non-receptor type 11 1.157
DNTT DNA nucleotidylexotransferase 1.157
NTRK3 neurotrophic tyrosine kinase, receptor, type 3 1.157
CD8A CD8a molecule 1.154
CD44 CD44 molecule (Indian blood group) 1.154
AHDC1 AT hook, DNA binding motif, containing 1 1.149
PRKACG protein kinase, cAMP-dependent, catalytic, gamma 1.149
SDHA succinate dehydrogenase complex, subunit A, flavoprotein (Fp) 1.145
FOXE1 forkhead box E1 1.145
DYTN dystrotelin 1.143
ACTB actin, beta 1.141
TNF tumor necrosis factor 1.141
FGF23 fibroblast growth factor 23 1.141
TMEM127 transmembrane protein 127 1.139
AR androgen receptor 1.136
VGLL2 vestigial-like family member 2 1.136
ALX1 ALX homeobox 1 1.132
FGF8 fibroblast growth factor 8 (androgen-induced) 1.131
CCNB3 cyclin B3 1.126
KMT2A lysine (K)-specific methyltransferase 2A 1.125
HMGB3 high mobility group box 3 1.125
PORCN porcupine homolog (Drosophila) 1.12
H3-3B H3.3 histone B 1.118
CR2 complement component (3d/Epstein Barr virus) receptor 2 1.117
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class) 1.117
PIP prolactin-induced protein 1.116
SRC SRC proto-oncogene, non-receptor tyrosine kinase 1.116
KITLG KIT ligand 1.115
NES nestin 1.115
COX6C cytochrome c oxidase subunit VIc 1.115
TMEM242 transmembrane protein 242 1.114
IFNA16 interferon, alpha 16 1.113
SUZ12 SUZ12 polycomb repressive complex 2 subunit 1.113
IFNA21 interferon, alpha 21 1.112
IFNA10 interferon, alpha 10 1.112
IFNA14 interferon, alpha 14 1.112
IFNA7 interferon, alpha 7 1.112
GPC3 glypican 3 1.111
IFNA6 interferon, alpha 6 1.111
IFNA8 interferon, alpha 8 1.111
YAP1 Yes-associated protein 1 1.11
IFNA5 interferon, alpha 5 1.11
SATB2 SATB homeobox 2 1.109
APC adenomatous polyposis coli 1.109
IFNA13 interferon, alpha 13 1.109
GRHL3 grainyhead-like 3 (Drosophila) 1.108
IFNA4 interferon, alpha 4 1.107
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 1.102
SHOC2 soc-2 suppressor of clear homolog (C. elegans) 1.098
B3GAT1 beta-1,3-glucuronyltransferase 1 1.093
INSYN2B inhibitory synaptic factor family member 2B 1.093
FOLH1 folate hydrolase (prostate-specific membrane antigen) 1 1.09
CHEK2 checkpoint kinase 2 1.089
SYNGAP1 synaptic Ras GTPase activating protein 1 1.087
RAD51B RAD51 paralog B 1.087
POLD1 polymerase (DNA directed), delta 1, catalytic subunit 1.086
CSNK1A1 casein kinase 1, alpha 1 1.084
GNAQ guanine nucleotide binding protein (G protein), q polypeptide 1.084
SRF serum response factor (c-fos serum response element-binding transcription factor) 1.084
GAPDH glyceraldehyde-3-phosphate dehydrogenase 1.083
VIM vimentin 1.083
BCR breakpoint cluster region 1.082
EPCAM epithelial cell adhesion molecule 1.08
CASR calcium-sensing receptor 1.079
RAB2A RAB2A, member RAS oncogene family 1.078
ELN elastin 1.077
ANKRD11 ankyrin repeat domain 11 1.075
CTAG1B cancer/testis antigen 1B 1.073
GH1 growth hormone 1 1.071
MYB v-myb avian myeloblastosis viral oncogene homolog 1.071
SERGEF secretion regulating guanine nucleotide exchange factor 1.07
PALB2 partner and localizer of BRCA2 1.066
TERT telomerase reverse transcriptase 1.065
COL6A3 collagen, type VI, alpha 3 1.064
CIB2 calcium and integrin binding family member 2 1.061
MYOCD myocardin 1.061
WWTR1 WW domain containing transcription regulator 1 1.051
RAPH1 Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 1.05
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 1.048
CDKN2B cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) 1.048
PPARA peroxisome proliferator-activated receptor alpha 1.048
FN1 fibronectin 1 1.048
RHEB Ras homolog enriched in brain 1.047
MED22 mediator complex subunit 22 1.044
FKBP1A FK506 binding protein 1A, 12kDa 1.044
FZD6 frizzled class receptor 6 1.044
SDHAF2 succinate dehydrogenase complex assembly factor 2 1.043
TMIE transmembrane inner ear 1.041
RETREG2 reticulophagy regulator family member 2 1.041
CD274 CD274 molecule 1.041
CRTC1 CREB regulated transcription coactivator 1 1.041
BCL6 B-cell CLL/lymphoma 6 1.041
PDE11A phosphodiesterase 11A 1.039
MAP3K5 mitogen-activated protein kinase kinase kinase 5 1.038
CENPC centromere protein C 1.037
ACKR3 atypical chemokine receptor 3 1.036
EGF epidermal growth factor 1.036
TYR tyrosinase 1.032
GH2 growth hormone 2 1.031
NCOA1 nuclear receptor coactivator 1 1.027
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1 1.026
SSTR2 somatostatin receptor 2 1.022
SPN sialophorin 1.022
RUNX2 runt-related transcription factor 2 1.021
ZNF791 zinc finger protein 791 1.019
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog 1.018
ENG endoglin 1.014
TP63 tumor protein p63 1.013
SRY sex determining region Y 1.013
NUTM1 NUT midline carcinoma, family member 1 1.013
AIP aryl hydrocarbon receptor interacting protein 1.011
CKMT2 creatine kinase, mitochondrial 2 (sarcomeric) 1.009
CFAP54 cilia and flagella associated 54 1.009
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2) 1.008
PTCH1 patched 1 1.008
DVL1 dishevelled segment polarity protein 1 1.007
FGF7 fibroblast growth factor 7 1.006
EIF3CL eukaryotic translation initiation factor 3, subunit C-like 1.006
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble 1.005
THY1 Thy-1 cell surface antigen 1.005
TNS2 tensin 2 1.005
FGF3 fibroblast growth factor 3 1.004
FGF10 fibroblast growth factor 10 1.004
SPRYD7 SPRY domain containing 7 1.004
GPR101 G protein-coupled receptor 101 1.002