Lissencephaly Gene Set

Dataset DISEASES Text-mining Gene-Disease Association Evidence Scores 2025
Category disease or phenotype associations
Type disease
Description A congenital nervous system abnormality characterized by the absence of folds in the cerebral cortex and caused_by defective neuronal migration during the 12th to 24th weeks of gestation. (Human Disease Ontology, DOID_0050453)
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Genes

762 genes co-occuring with the disease Lissencephaly in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores 2025 dataset.

Symbol Name Standardized Value
PAFAH1B1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) 3.678
NDEL1 nudE neurodevelopment protein 1-like 1 3.458
TUBA1A tubulin, alpha 1a 3.402
NDE1 nudE neurodevelopment protein 1 3.372
DCX doublecortin 3.319
RELN reelin 3.212
ARX aristaless related homeobox 3.078
TUBB2B tubulin, beta 2B class IIb 2.97
POMGNT1 protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-) 2.936
POMT1 protein-O-mannosyltransferase 1 2.933
GPR101 G protein-coupled receptor 101 2.905
POMT2 protein-O-mannosyltransferase 2 2.884
RMND5A required for meiotic nuclear division 5 homolog A (S. cerevisiae) 2.867
DAG1 dystroglycan 1 (dystrophin-associated glycoprotein 1) 2.867
TUBG1 tubulin, gamma 1 2.845
WDR62 WD repeat domain 62 2.842
FKTN fukutin 2.839
NUDC nudC nuclear distribution protein 2.775
VLDLR very low density lipoprotein receptor 2.775
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon 2.762
FKRP fukutin related protein 2.726
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1 2.681
RXYLT1 ribitol xylosyltransferase 1 2.653
TUBA8 tubulin, alpha 8 2.626
TUBB3 tubulin, beta 3 class III 2.619
ADGRG1 adhesion G protein-coupled receptor G1 2.609
KATNB1 katanin p80 (WD repeat containing) subunit B 1 2.591
DISC1 disrupted in schizophrenia 1 2.571
LRP8 low density lipoprotein receptor-related protein 8, apolipoprotein e receptor 2.545
BICD2 bicaudal D homolog 2 (Drosophila) 2.529
TMTC3 transmembrane and tetratricopeptide repeat containing 3 2.5
TBR1 T-box, brain, 1 2.499
CDK5 cyclin-dependent kinase 5 2.492
RANBP9 RAN binding protein 9 2.488
TUBB4A tubulin, beta 4A class IVa 2.484
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila) 2.481
TUBB2A tubulin, beta 2A class IIa 2.467
ARFGEF2 ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) 2.459
CRPPA CDP-L-ribitol pyrophosphorylase A 2.443
KIF5C kinesin family member 5C 2.408
POMGNT2 protein O-linked mannose N-acetylglucosaminyltransferase 2 (beta 1,4-) 2.408
FLNA filamin A, alpha 2.407
B3GALNT2 beta-1,3-N-acetylgalactosaminyltransferase 2 2.391
CDK5RAP2 CDK5 regulatory subunit associated protein 2 2.367
KIF2A kinesin heavy chain member 2A 2.365
TUBB tubulin, beta class I 2.294
MCPH1 microcephalin 1 2.291
PAX6 paired box 6 2.288
EOMES eomesodermin 2.285
EMX1 empty spiracles homeobox 1 2.269
CLIP1 CAP-GLY domain containing linker protein 1 2.262
DCTN2 dynactin 2 (p50) 2.261
PAFAH1B3 platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa) 2.261
DCLK1 doublecortin-like kinase 1 2.243
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein) 2.241
BICD1 bicaudal D homolog 1 (Drosophila) 2.24
DCLK2 doublecortin-like kinase 2 2.221
EML1 echinoderm microtubule associated protein like 1 2.219
FOXG1 forkhead box G1 2.213
CRK v-crk avian sarcoma virus CT10 oncogene homolog 2.209
GID8 GID complex subunit 8 2.202
PAFAH1B2 platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa) 2.199
CRADD CASP2 and RIPK1 domain containing adaptor with death domain 2.19
MKLN1 muskelin 1, intracellular mediator containing kelch motifs 2.179
RTTN rotatin 2.179
POMK protein-O-mannose kinase 2.173
ACTG1 actin gamma 1 2.169
TUBB6 tubulin, beta 6 class V 2.16
DCTN1 dynactin 1 2.146
CUX1 cut-like homeobox 1 2.126
GMPPB GDP-mannose pyrophosphorylase B 2.125
STIL SCL/TAL1 interrupting locus 2.124
STXBP1 syntaxin binding protein 1 2.112
CNTLN centlein, centrosomal protein 2.11
TRNP1 TMF1-regulated nuclear protein 1 2.098
AIP aryl hydrocarbon receptor interacting protein 2.088
PCNT pericentrin 2.067
EMX2 empty spiracles homeobox 2 2.066
KIF1A kinesin family member 1A 2.064
NES nestin 2.05
LARGE1 LARGE xylosyl- and glucuronyltransferase 1 2.05
NUDCD2 NudC domain containing 2 2.047
ARMC8 armadillo repeat containing 8 2.046
CDKL5 cyclin-dependent kinase-like 5 2.044
TUBA4A tubulin, alpha 4a 2.033
SATB2 SATB homeobox 2 2.026
LAMA2 laminin, alpha 2 2.026
MECP2 methyl CpG binding protein 2 2.011
NRXN1 neurexin 1 2.011
LAMB1 laminin, beta 1 1.99
CEP85L centrosomal protein 85kDa-like 1.987
PVALB parvalbumin 1.986
DYNLL1 dynein, light chain, LC8-type 1 1.966
APLP2 amyloid beta (A4) precursor-like protein 2 1.957
SCN1A sodium channel, voltage gated, type I alpha subunit 1.953
CALB1 calbindin 1, 28kDa 1.944
HOOK3 hook microtubule-tethering protein 3 1.934
MACF1 microtubule-actin crosslinking factor 1 1.932
APLP1 amyloid beta (A4) precursor-like protein 1 1.929
MAPRE3 microtubule-associated protein, RP/EB family, member 3 1.927
NRXN2 neurexin 2 1.923
CALB2 calbindin 2 1.911
TSC2 tuberous sclerosis 2 1.896
EGFLAM EGF-like, fibronectin type III and laminin G domains 1.896
ARHGAP11B Rho GTPase activating protein 11B 1.894
RBFOX3 RNA binding protein, fox-1 homolog (C. elegans) 3 1.889
GID4 GID complex subunit 4 1.881
PCDH19 protocadherin 19 1.88
MAP1B microtubule-associated protein 1B 1.88
CEP135 centrosomal protein 135kDa 1.876
BICDL1 BICD family like cargo adaptor 1 1.876
CDC42 cell division cycle 42 1.874
WDR47 WD repeat domain 47 1.87
FMR1 fragile X mental retardation 1 1.869
SHH sonic hedgehog 1.864
CEP63 centrosomal protein 63kDa 1.862
GHRH growth hormone releasing hormone 1.855
FOXP2 forkhead box P2 1.855
SCN2A sodium channel, voltage gated, type II alpha subunit 1.85
TRARG1 trafficking regulator of GLUT4 (SLC2A4) 1 1.831
CEP152 centrosomal protein 152kDa 1.827
RHOA ras homolog family member A 1.824
RANBP10 RAN binding protein 10 1.823
GFAP glial fibrillary acidic protein 1.823
TMTC4 transmembrane and tetratricopeptide repeat containing 4 1.822
FEZ1 fasciculation and elongation protein zeta 1 (zygin I) 1.813
DCDC2 doublecortin domain containing 2 1.812
WDR26 WD repeat domain 26 1.803
WDR81 WD repeat domain 81 1.802
PPP1R9B protein phosphatase 1, regulatory subunit 9B 1.792
KCNQ2 potassium channel, voltage gated KQT-like subfamily Q, member 2 1.79
PHC3 polyhomeotic homolog 3 (Drosophila) 1.788
SRPX2 sushi-repeat containing protein, X-linked 2 1.779
AGRN agrin 1.776
SUN1 Sad1 and UNC84 domain containing 1 1.772
TMTC1 transmembrane and tetratricopeptide repeat containing 1 1.772
CIB3 calcium and integrin binding family member 3 1.771
GAD1 glutamate decarboxylase 1 (brain, 67kDa) 1.769
DMD dystrophin 1.766
SOX2 SRY (sex determining region Y)-box 2 1.763
PCDH10 protocadherin 10 1.759
B4GAT1 beta-1,4-glucuronyltransferase 1 1.755
SYNE2 spectrin repeat containing, nuclear envelope 2 1.755
DEPDC5 DEP domain containing 5 1.755
APBB1 amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65) 1.751
CDH2 cadherin 2, type 1, N-cadherin (neuronal) 1.749
CFL1 cofilin 1 (non-muscle) 1.745
SST somatostatin 1.743
NEUROG2 neurogenin 2 1.743
DPM3 dolichyl-phosphate mannosyltransferase polypeptide 3 1.741
HSPG2 heparan sulfate proteoglycan 2 1.741
CDH17 cadherin 17, LI cadherin (liver-intestine) 1.733
APP amyloid beta (A4) precursor protein 1.732
MYH14 myosin, heavy chain 14, non-muscle 1.72
FABP7 fatty acid binding protein 7, brain 1.718
MTOR mechanistic target of rapamycin (serine/threonine kinase) 1.709
SPAST spastin 1.708
CFL2 cofilin 2 (muscle) 1.706
TUBGCP2 tubulin, gamma complex associated protein 2 1.702
ERMARD ER membrane-associated RNA degradation 1.699
SHANK3 SH3 and multiple ankyrin repeat domains 3 1.688
TMX2 thioredoxin-related transmembrane protein 2 1.682
DLX2 distal-less homeobox 2 1.682
L1CAM L1 cell adhesion molecule 1.682
TMTC2 transmembrane and tetratricopeptide repeat containing 2 1.68
AUTS2 autism susceptibility candidate 2 1.676
LGALS4 lectin, galactoside-binding, soluble, 4 1.675
DCHS1 dachsous cadherin-related 1 1.675
LAMC3 laminin, gamma 3 1.674
DIXDC1 DIX domain containing 1 1.673
DLG4 discs, large homolog 4 (Drosophila) 1.672
CLASP2 cytoplasmic linker associated protein 2 1.671
MEN1 multiple endocrine neoplasia I 1.669
OPHN1 oligophrenin 1 1.666
ACTR10 actin-related protein 10 homolog (S. cerevisiae) 1.666
MAP2 microtubule-associated protein 2 1.664
NIN ninein (GSK3B interacting protein) 1.661
RAB6A RAB6A, member RAS oncogene family 1.659
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 1.658
DLX5 distal-less homeobox 5 1.657
FLRT1 fibronectin leucine rich transmembrane protein 1 1.657
UBE3A ubiquitin protein ligase E3A 1.648
PLEKHG6 pleckstrin homology domain containing, family G (with RhoGef domain) member 6 1.646
MAEA macrophage erythroblast attacher 1.644
BDNF brain-derived neurotrophic factor 1.64
PCM1 pericentriolar material 1 1.639
GSX2 GS homeobox 2 1.638
TUBB4B tubulin, beta 4B class IVb 1.637
ARHGEF6 Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6 1.636
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2 1.636
CUX2 cut-like homeobox 2 1.635
PRL prolactin 1.634
PQBP1 polyglutamine binding protein 1 1.632
DOLK dolichol kinase 1.632
RAB11A RAB11A, member RAS oncogene family 1.631
TRAK1 trafficking protein, kinesin binding 1 1.63
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 1.629
POTEF POTE ankyrin domain family, member F 1.628
DPM2 dolichyl-phosphate mannosyltransferase polypeptide 2, regulatory subunit 1.624
KATNAL1 katanin p60 subunit A-like 1 1.624
TSEN54 TSEN54 tRNA splicing endonuclease subunit 1.622
POU3F2 POU class 3 homeobox 2 1.618
NUDCD3 NudC domain containing 3 1.616
KCNT1 potassium channel, sodium activated subfamily T, member 1 1.614
TUBA1C tubulin, alpha 1c 1.612
COL4A1 collagen, type IV, alpha 1 1.61
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B 1.605
PIDD1 p53-induced death domain protein 1 1.604
ACTB actin, beta 1.604
DPM1 dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit 1.603
ZNF335 zinc finger protein 335 1.596
ZIC2 Zic family member 2 1.594
HOPX HOP homeobox 1.594
PRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha 1.588
ASCL1 achaete-scute family bHLH transcription factor 1 1.582
DMRTA2 DMRT-like family A2 1.579
CHD8 chromodomain helicase DNA binding protein 8 1.578
ASTN1 astrotactin 1 1.573
GSK3B glycogen synthase kinase 3 beta 1.572
DSCAM Down syndrome cell adhesion molecule 1.572
CENPE centromere protein E, 312kDa 1.571
SYNE1 spectrin repeat containing, nuclear envelope 1 1.57
MAPRE1 microtubule-associated protein, RP/EB family, member 1 1.567
SCN8A sodium channel, voltage gated, type VIII alpha subunit 1.564
FEZF2 FEZ family zinc finger 2 1.564
DYNC1I1 dynein, cytoplasmic 1, intermediate chain 1 1.562
IQGAP1 IQ motif containing GTPase activating protein 1 1.562
GRIN2A glutamate receptor, ionotropic, N-methyl D-aspartate 2A 1.56
DAB1 Dab, reelin signal transducer, homolog 1 (Drosophila) 1.557
NUMA1 nuclear mitotic apparatus protein 1 1.557
AKT1 v-akt murine thymoma viral oncogene homolog 1 1.552
NUMBL numb homolog (Drosophila)-like 1.552
FAT4 FAT atypical cadherin 4 1.548
ZIC1 Zic family member 1 1.546
TSEN34 TSEN34 tRNA splicing endonuclease subunit 1.545
POMC proopiomelanocortin 1.542
MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3 1.541
TUBGCP4 tubulin, gamma complex associated protein 4 1.541
NFASC neurofascin 1.54
DPYSL2 dihydropyrimidinase-like 2 1.539
IGF1 insulin-like growth factor 1 (somatomedin C) 1.537
OLIG2 oligodendrocyte lineage transcription factor 2 1.536
CKMT1B creatine kinase, mitochondrial 1B 1.533
KALRN kalirin, RhoGEF kinase 1.526
CKB creatine kinase, brain 1.525
CKMT2 creatine kinase, mitochondrial 2 (sarcomeric) 1.524
CKM creatine kinase, muscle 1.524
CCDC88A coiled-coil domain containing 88A 1.522
NUMB numb homolog (Drosophila) 1.522
TUBGCP6 tubulin, gamma complex associated protein 6 1.521
RAB5A RAB5A, member RAS oncogene family 1.52
LHX2 LIM homeobox 2 1.518
EGF epidermal growth factor 1.518
FXR2 fragile X mental retardation, autosomal homolog 2 1.517
KNL1 kinetochore scaffold 1 1.515
SEMA3A sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A 1.513
KIF5A kinesin family member 5A 1.51
SRGAP2C SLIT-ROBO Rho GTPase activating protein 2C 1.508
MYO5A myosin VA (heavy chain 12, myoxin) 1.502
SYNE4 spectrin repeat containing, nuclear envelope family member 4 1.5
CNTN2 contactin 2 (axonal) 1.495
PRKACB protein kinase, cAMP-dependent, catalytic, beta 1.495
MAPT microtubule-associated protein tau 1.493
TRAK2 trafficking protein, kinesin binding 2 1.493
USP8 ubiquitin specific peptidase 8 1.492
NEUROD1 neuronal differentiation 1 1.49
RABIF RAB interacting factor 1.49
CENPF centromere protein F, 350/400kDa 1.488
PTPRZ1 protein tyrosine phosphatase, receptor-type, Z polypeptide 1 1.488
FYN FYN proto-oncogene, Src family tyrosine kinase 1.487
TUBB1 tubulin, beta 1 class VI 1.484
DLX1 distal-less homeobox 1 1.482
TUBA3E tubulin, alpha 3e 1.48
ARL13B ADP-ribosylation factor-like 13B 1.479
DYNLT1 dynein, light chain, Tctex-type 1 1.474
ZW10 zw10 kinetochore protein 1.474
TBCD tubulin folding cofactor D 1.472
GABRA1 gamma-aminobutyric acid (GABA) A receptor, alpha 1 1.472
KATNAL2 katanin p60 subunit A-like 2 1.472
NOTCH2NLB notch 2 N-terminal like B 1.47
SPON1 spondin 1, extracellular matrix protein 1.469
CNTNAP2 contactin associated protein-like 2 1.467
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3 1.466
NUDCD1 NudC domain containing 1 1.465
RND2 Rho family GTPase 2 1.465
CEP170 centrosomal protein 170kDa 1.464
DNAH8 dynein, axonemal, heavy chain 8 1.463
NUP133 nucleoporin 133kDa 1.459
PTEN phosphatase and tensin homolog 1.459
OFD1 oral-facial-digital syndrome 1 1.459
AKT3 v-akt murine thymoma viral oncogene homolog 3 1.459
KATNA1 katanin p60 (ATPase containing) subunit A 1 1.458
CALML6 calmodulin-like 6 1.455
SUN2 Sad1 and UNC84 domain containing 2 1.455
CALML4 calmodulin-like 4 1.455
PCDH11X protocadherin 11 X-linked 1.455
CALML3 calmodulin-like 3 1.453
CALM3 calmodulin 3 (phosphorylase kinase, delta) 1.453
SYN1 synapsin I 1.453
CALML5 calmodulin-like 5 1.452
SLC25A22 solute carrier family 25 (mitochondrial carrier: glutamate), member 22 1.451
GPHN gephyrin 1.451
TUBA1B tubulin, alpha 1b 1.45
SIX3 SIX homeobox 3 1.449
FXR1 fragile X mental retardation, autosomal homolog 1 1.444
PARD3 par-3 family cell polarity regulator 1.444
PHGDH phosphoglycerate dehydrogenase 1.444
KIFBP kinesin family binding protein 1.442
PRKACA protein kinase, cAMP-dependent, catalytic, alpha 1.442
PRKACG protein kinase, cAMP-dependent, catalytic, gamma 1.441
SHANK2 SH3 and multiple ankyrin repeat domains 2 1.439
OTX2 orthodenticle homeobox 2 1.439
SMG6 SMG6 nonsense mediated mRNA decay factor 1.438
BICDL2 BICD family like cargo adaptor 2 1.431
TBCB tubulin folding cofactor B 1.429
COPB1 coatomer protein complex, subunit beta 1 1.429
GPSM2 G-protein signaling modulator 2 1.427
EFHC1 EF-hand domain (C-terminal) containing 1 1.426
SRD5A3 steroid 5 alpha-reductase 3 1.425
TUBAL3 tubulin, alpha-like 3 1.419
KIAA0319 KIAA0319 1.416
FGF2 fibroblast growth factor 2 (basic) 1.416
BLOC1S2 biogenesis of lysosomal organelles complex-1, subunit 2 1.415
KCNQ3 potassium channel, voltage gated KQT-like subfamily Q, member 3 1.415
CLASRP CLK4-associating serine/arginine rich protein 1.413
NEDD1 neural precursor cell expressed, developmentally down-regulated 1 1.413
ATAT1 alpha tubulin acetyltransferase 1 1.413
DNAAF4 dynein axonemal assembly factor 4 1.409
TSC1 tuberous sclerosis 1 1.406
TUBD1 tubulin, delta 1 1.402
ACTR3B ARP3 actin-related protein 3 homolog B (yeast) 1.401
SLIT3 slit homolog 3 (Drosophila) 1.401
CLASP1 cytoplasmic linker associated protein 1 1.4
PHC1 polyhomeotic homolog 1 (Drosophila) 1.4
GAPDH glyceraldehyde-3-phosphate dehydrogenase 1.399
TSEN2 TSEN2 tRNA splicing endonuclease subunit 1.397
CKAP5 cytoskeleton associated protein 5 1.396
KLC2 kinesin light chain 2 1.394
ACTR3C ARP3 actin-related protein 3 homolog C (yeast) 1.39
RANBP2 RAN binding protein 2 1.39
FOXC1 forkhead box C1 1.387
BHLHA9 basic helix-loop-helix family, member a9 1.383
STMN1 stathmin 1 1.383
SASS6 spindle assembly 6 homolog (C. elegans) 1.38
TPPP tubulin polymerization promoting protein 1.379
GNAS GNAS complex locus 1.379
UTRN utrophin 1.375
LMNB2 lamin B2 1.373
NR2F1 nuclear receptor subfamily 2, group F, member 1 1.372
SRC SRC proto-oncogene, non-receptor tyrosine kinase 1.372
TP53 tumor protein p53 1.371
CCDC141 coiled-coil domain containing 141 1.367
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha 1.365
NLGN4X neuroligin 4, X-linked 1.364
FGF8 fibroblast growth factor 8 (androgen-induced) 1.364
RAB11FIP3 RAB11 family interacting protein 3 (class II) 1.364
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila) 1.362
SLIT1 slit homolog 1 (Drosophila) 1.358
HTT huntingtin 1.358
CHAMP1 chromosome alignment maintaining phosphoprotein 1 1.356
H3C13 H3 clustered histone 13 1.356
CRKL v-crk avian sarcoma virus CT10 oncogene homolog-like 1.356
KLC3 kinesin light chain 3 1.355
TUBA3D tubulin, alpha 3d 1.352
LAMA1 laminin, alpha 1 1.352
NRG1 neuregulin 1 1.35
ADGRL2 adhesion G protein-coupled receptor L2 1.35
H3-5 H3.5 histone 1.349
H3-4 H3.4 histone, cluster member 1.349
BBS4 Bardet-Biedl syndrome 4 1.348
SPTAN1 spectrin, alpha, non-erythrocytic 1 1.346
SRGAP2 SLIT-ROBO Rho GTPase activating protein 2 1.344
PARD6A par-6 family cell polarity regulator alpha 1.343
CAMSAP1 calmodulin regulated spectrin-associated protein 1 1.343
H3-3B H3.3 histone B 1.342
NTN1 netrin 1 1.342
LHX6 LIM homeobox 6 1.34
H3C12 H3 clustered histone 12 1.338
GABRB3 gamma-aminobutyric acid (GABA) A receptor, beta 3 1.338
WASL Wiskott-Aldrich syndrome-like 1.337
NTRK2 neurotrophic tyrosine kinase, receptor, type 2 1.335
SH3RF1 SH3 domain containing ring finger 1 1.335
GSX1 GS homeobox 1 1.332
DYNC1LI1 dynein, cytoplasmic 1, light intermediate chain 1 1.332
CASP2 caspase 2, apoptosis-related cysteine peptidase 1.332
FLNC filamin C, gamma 1.332
MYO5B myosin VB 1.331
GHRHR growth hormone releasing hormone receptor 1.331
FLNB filamin B, beta 1.33
TMEM14B transmembrane protein 14B 1.329
CLIP2 CAP-GLY domain containing linker protein 2 1.325
RBMX RNA binding motif protein, X-linked 1.325
KATNBL1 katanin p80 subunit B-like 1 1.324
NKX2-1 NK2 homeobox 1 1.324
KIF26A kinesin family member 26A 1.323
NCK2 NCK adaptor protein 2 1.321
LMNA lamin A/C 1.319
ATP6V0A2 ATPase, H+ transporting, lysosomal V0 subunit a2 1.318
TXNDC15 thioredoxin domain containing 15 1.317
ILK integrin-linked kinase 1.316
SNAPIN SNAP-associated protein 1.315
PLP1 proteolipid protein 1 1.311
ADSL adenylosuccinate lyase 1.311
KIF21A kinesin family member 21A 1.31
LIMK1 LIM domain kinase 1 1.307
ERBB4 erb-b2 receptor tyrosine kinase 4 1.307
KIF2C kinesin family member 2C 1.307
RAPGEF2 Rap guanine nucleotide exchange factor (GEF) 2 1.307
PLEK pleckstrin 1.306
RORB RAR-related orphan receptor B 1.305
ACTR1A ARP1 actin-related protein 1 homolog A, centractin alpha (yeast) 1.305
DYNC2H1 dynein, cytoplasmic 2, heavy chain 1 1.305
GBX2 gastrulation brain homeobox 2 1.303
FIGN fidgetin 1.303
SLC12A5 solute carrier family 12 (potassium/chloride transporter), member 5 1.302
FN1 fibronectin 1 1.3
CASP3 caspase 3, apoptosis-related cysteine peptidase 1.296
CABLES1 Cdk5 and Abl enzyme substrate 1 1.292
CREB1 cAMP responsive element binding protein 1 1.291
NPY neuropeptide Y 1.287
PLEK2 pleckstrin 2 1.287
KIF3A kinesin family member 3A 1.287
SYNGAP1 synaptic Ras GTPase activating protein 1 1.286
KIF7 kinesin family member 7 1.286
ARHGEF9 Cdc42 guanine nucleotide exchange factor (GEF) 9 1.285
FGF13 fibroblast growth factor 13 1.282
ISL1 ISL LIM homeobox 1 1.282
RAPGEF1 Rap guanine nucleotide exchange factor (GEF) 1 1.281
PNPO pyridoxamine 5'-phosphate oxidase 1.28
MYO5C myosin VC 1.278
GHR growth hormone receptor 1.278
DYNLRB1 dynein, light chain, roadblock-type 1 1.277
CEP83 centrosomal protein 83kDa 1.277
ALG13 ALG13, UDP-N-acetylglucosaminyltransferase subunit 1.275
ROBO2 roundabout, axon guidance receptor, homolog 2 (Drosophila) 1.273
ZIC3 Zic family member 3 1.273
IPO13 importin 13 1.273
USP48 ubiquitin specific peptidase 48 1.272
CACNA1A calcium channel, voltage-dependent, P/Q type, alpha 1A subunit 1.27
SRGAP3 SLIT-ROBO Rho GTPase activating protein 3 1.269
MAGOH mago-nashi homolog, proliferation-associated (Drosophila) 1.268
NF1 neurofibromin 1 1.268
TBC1D24 TBC1 domain family, member 24 1.267
AP1S2 adaptor-related protein complex 1, sigma 2 subunit 1.265
CHCHD2 coiled-coil-helix-coiled-coil-helix domain containing 2 1.262
ANK3 ankyrin 3, node of Ranvier (ankyrin G) 1.261
LHX5 LIM homeobox 5 1.26
ZNF519 zinc finger protein 519 1.258
TUB tubby bipartite transcription factor 1.258
SOX1 SRY (sex determining region Y)-box 1 1.258
STMN2 stathmin 2 1.255
CTNNA2 catenin (cadherin-associated protein), alpha 2 1.253
NLGN2 neuroligin 2 1.253
FAM107A family with sequence similarity 107, member A 1.252
USP9X ubiquitin specific peptidase 9, X-linked 1.251
MPV17L MPV17 mitochondrial membrane protein-like 1.25
SOX3 SRY (sex determining region Y)-box 3 1.25
DCDC1 doublecortin domain containing 1 1.249
RASA1 RAS p21 protein activator (GTPase activating protein) 1 1.247
DOCK7 dedicator of cytokinesis 7 1.244
SCN1B sodium channel, voltage gated, type I beta subunit 1.239
NKX2-2 NK2 homeobox 2 1.238
NOTCH2NLA notch 2 N-terminal like A 1.238
HIC1 hypermethylated in cancer 1 1.236
NEUROD6 neuronal differentiation 6 1.236
CDK1 cyclin-dependent kinase 1 1.234
MYC v-myc avian myelocytomatosis viral oncogene homolog 1.234
ETV1 ets variant 1 1.234
CELSR3 cadherin, EGF LAG seven-pass G-type receptor 3 1.231
GLI3 GLI family zinc finger 3 1.231
AFDN afadin, adherens junction formation factor 1.231
LRRK2 leucine-rich repeat kinase 2 1.23
ETV2 ets variant 2 1.229
NPRL3 nitrogen permease regulator-like 3 (S. cerevisiae) 1.227
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma 1.227
HOOK1 hook microtubule-tethering protein 1 1.225
HAPLN1 hyaluronan and proteoglycan link protein 1 1.224
LGI1 leucine-rich, glioma inactivated 1 1.224
NBEA neurobeachin 1.223
PDE4A phosphodiesterase 4A, cAMP-specific 1.217
CEP120 centrosomal protein 120kDa 1.217
EEA1 early endosome antigen 1 1.216
LMNB1 lamin B1 1.216
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7 1.215
SZT2 seizure threshold 2 homolog (mouse) 1.215
GRB2 growth factor receptor-bound protein 2 1.214
KIF21B kinesin family member 21B 1.212
LZTS3 leucine zipper, putative tumor suppressor family member 3 1.212
CEP41 centrosomal protein 41kDa 1.211
MEF2C myocyte enhancer factor 2C 1.211
KIF5B kinesin family member 5B 1.21
TTL tubulin tyrosine ligase 1.209
DNM1 dynamin 1 1.207
RAB3GAP1 RAB3 GTPase activating protein subunit 1 (catalytic) 1.206
NLGN3 neuroligin 3 1.205
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta 1.203
GABRG2 gamma-aminobutyric acid (GABA) A receptor, gamma 2 1.203
MAP6 microtubule-associated protein 6 1.203
CDH8 cadherin 8, type 2 1.203
RAB18 RAB18, member RAS oncogene family 1.202
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta 1.201
AURKA aurora kinase A 1.199
GRIA1 glutamate receptor, ionotropic, AMPA 1 1.199
PLK4 polo-like kinase 4 1.198
IFT88 intraflagellar transport 88 1.194
KLC1 kinesin light chain 1 1.194
PFN1 profilin 1 1.193
HDAC6 histone deacetylase 6 1.192
SNAP25 synaptosomal-associated protein, 25kDa 1.192
DBX1 developing brain homeobox 1 1.192
ANK2 ankyrin 2, neuronal 1.191
CAMSAP2 calmodulin regulated spectrin-associated protein family, member 2 1.19
DES desmin 1.189
TH tyrosine hydroxylase 1.189
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta 1.189
RARS2 arginyl-tRNA synthetase 2, mitochondrial 1.188
ZWILCH zwilch kinetochore protein 1.188
CDK5R1 cyclin-dependent kinase 5, regulatory subunit 1 (p35) 1.187
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta 1.187
IFT172 intraflagellar transport 172 1.186
TUBB8 tubulin, beta 8 class VIII 1.185
MAGOHB mago-nashi homolog B (Drosophila) 1.184
FLRT3 fibronectin leucine rich transmembrane protein 3 1.184
CHMP1A charged multivesicular body protein 1A 1.184
NEXN nexilin (F actin binding protein) 1.183
GPR161 G protein-coupled receptor 161 1.183
HOOK2 hook microtubule-tethering protein 2 1.183
NRXN3 neurexin 3 1.182
PRUNE1 prune exopolyphosphatase 1 1.182
ZNF365 zinc finger protein 365 1.182
VRK1 vaccinia related kinase 1 1.181
CHD7 chromodomain helicase DNA binding protein 7 1.18
PLEC plectin 1.18
HES5 hes family bHLH transcription factor 5 1.18
PSEN1 presenilin 1 1.179
PXDN peroxidasin 1.177
JUN jun proto-oncogene 1.175
PDE4B phosphodiesterase 4B, cAMP-specific 1.175
GCNT2 glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) 1.172
DAW1 dynein assembly factor with WDR repeat domains 1 1.171
NGF nerve growth factor (beta polypeptide) 1.171
ZNF34 zinc finger protein 34 1.17
IQSEC2 IQ motif and Sec7 domain 2 1.17
NEFM neurofilament, medium polypeptide 1.17
EXOSC3 exosome component 3 1.169
ALB albumin 1.168
FOXP1 forkhead box P1 1.167
INSC inscuteable homolog (Drosophila) 1.167
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) 1.165
MARK2 MAP/microtubule affinity-regulating kinase 2 1.164
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) 1.163
KIF24 kinesin family member 24 1.163
ANKLE2 ankyrin repeat and LEM domain containing 2 1.162
BMP4 bone morphogenetic protein 4 1.161
PFN3 profilin 3 1.158
DICER1 dicer 1, ribonuclease type III 1.158
SNPH syntaphilin 1.156
GDNF glial cell derived neurotrophic factor 1.155
EFNB3 ephrin-B3 1.155
NRCAM neuronal cell adhesion molecule 1.155
PXDNL peroxidasin-like 1.154
FOXJ1 forkhead box J1 1.153
EMD emerin 1.153
SYP synaptophysin 1.152
CACNA1C calcium channel, voltage-dependent, L type, alpha 1C subunit 1.152
CAMK2G calcium/calmodulin-dependent protein kinase II gamma 1.151
SRY sex determining region Y 1.151
KIF11 kinesin family member 11 1.15
DYNC1I2 dynein, cytoplasmic 1, intermediate chain 2 1.149
POU3F3 POU class 3 homeobox 3 1.149
DNM2 dynamin 2 1.148
TRIM8 tripartite motif containing 8 1.147
SLCO6A1 solute carrier organic anion transporter family, member 6A1 1.146
GOLGA2 golgin A2 1.145
PALMD palmdelphin 1.143
EPHA4 EPH receptor A4 1.14
KIF2B kinesin family member 2B 1.14
PNKP polynucleotide kinase 3'-phosphatase 1.137
SSBP3 single stranded DNA binding protein 3 1.137
MAP7 microtubule-associated protein 7 1.136
MARCKS myristoylated alanine-rich protein kinase C substrate 1.133
PFN4 profilin family, member 4 1.132
DIAPH3 diaphanous-related formin 3 1.132
MFSD8 major facilitator superfamily domain containing 8 1.131
AXL AXL receptor tyrosine kinase 1.129
SUOX sulfite oxidase 1.129
CUL5 cullin 5 1.129
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 1.128
ZNF81 zinc finger protein 81 1.128
FGF10 fibroblast growth factor 10 1.126
SCN3A sodium channel, voltage gated, type III alpha subunit 1.124
TP73 tumor protein p73 1.124
NEUROG1 neurogenin 1 1.123
NLGN1 neuroligin 1 1.121
CLN5 ceroid-lipofuscinosis, neuronal 5 1.12
RAB39B RAB39B, member RAS oncogene family 1.12
DYNC1LI2 dynein, cytoplasmic 1, light intermediate chain 2 1.12
PLXNA3 plexin A3 1.12
SSTR5 somatostatin receptor 5 1.119
PLA2G7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) 1.119
PRRT2 proline-rich transmembrane protein 2 1.118
KANK1 KN motif and ankyrin repeat domains 1 1.118
CAMK4 calcium/calmodulin-dependent protein kinase IV 1.116
DMRT3 doublesex and mab-3 related transcription factor 3 1.116
ARF6 ADP-ribosylation factor 6 1.111
PLXNA2 plexin A2 1.111
WAS Wiskott-Aldrich syndrome 1.11
FMN2 formin 2 1.11
CTU2 cytosolic thiouridylase subunit 2 homolog (S. pombe) 1.11
PPP4C protein phosphatase 4, catalytic subunit 1.108
EN1 engrailed homeobox 1 1.108
PMM2 phosphomannomutase 2 1.106
PIGW phosphatidylinositol glycan anchor biosynthesis, class W 1.106
UGDH UDP-glucose 6-dehydrogenase 1.106
PEPD peptidase D 1.105
IGSF1 immunoglobulin superfamily, member 1 1.105
PSAT1 phosphoserine aminotransferase 1 1.105
AKNA AT-hook transcription factor 1.104
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2 1.104
EFNA5 ephrin-A5 1.103
DBN1 drebrin 1 1.102
CACNB4 calcium channel, voltage-dependent, beta 4 subunit 1.102
CAPN8 calpain 8 1.101
ALDH7A1 aldehyde dehydrogenase 7 family, member A1 1.101
LARGE2 LARGE xylosyl- and glucuronyltransferase 2 1.099
LMX1A LIM homeobox transcription factor 1, alpha 1.099
LAMC1 laminin, gamma 1 (formerly LAMB2) 1.099
SHANK1 SH3 and multiple ankyrin repeat domains 1 1.099
TMEM260 transmembrane protein 260 1.099
RAB8A RAB8A, member RAS oncogene family 1.098
WNT3A wingless-type MMTV integration site family, member 3A 1.096
BCAN brevican 1.094
TBC1D23 TBC1 domain family, member 23 1.089
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal) 1.088
MAPK8IP1 mitogen-activated protein kinase 8 interacting protein 1 1.087
TOGARAM1 TOG array regulator of axonemal microtubules 1 1.086
BHLHE22 basic helix-loop-helix family, member e22 1.086
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8 1.085
WDR89 WD repeat domain 89 1.083
ALG1 ALG1, chitobiosyldiphosphodolichol beta-mannosyltransferase 1.08
PIGQ phosphatidylinositol glycan anchor biosynthesis, class Q 1.08
ROBO3 roundabout, axon guidance receptor, homolog 3 (Drosophila) 1.079
KRBOX4 KRAB box domain containing 4 1.079
KIF13B kinesin family member 13B 1.079
EPHA1 EPH receptor A1 1.078
TIAM1 T-cell lymphoma invasion and metastasis 1 1.078
ARHGAP1 Rho GTPase activating protein 1 1.078
MLPH melanophilin 1.077
FDXACB1 ferredoxin-fold anticodon binding domain containing 1 1.076
DCTN5 dynactin 5 (p25) 1.075
MAP9 microtubule-associated protein 9 1.074
FGF17 fibroblast growth factor 17 1.071
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta 1.071
NEFL neurofilament, light polypeptide 1.071
APPL1 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1 1.07
BAIAP2 BAI1-associated protein 2 1.069
WWOX WW domain containing oxidoreductase 1.069
SGCE sarcoglycan, epsilon 1.068
GMPPA GDP-mannose pyrophosphorylase A 1.067
TGFB1 transforming growth factor, beta 1 1.066
VASP vasodilator-stimulated phosphoprotein 1.066
RHO rhodopsin 1.066
DTNBP1 dystrobrevin binding protein 1 1.065
SPTBN2 spectrin, beta, non-erythrocytic 2 1.065
FGF4 fibroblast growth factor 4 1.064
CTNND2 catenin (cadherin-associated protein), delta 2 1.064
TRAPPC11 trafficking protein particle complex 11 1.063
POU3F4 POU class 3 homeobox 4 1.062
NEUROG3 neurogenin 3 1.062
COL3A1 collagen, type III, alpha 1 1.061
CCP110 centriolar coiled coil protein 110kDa 1.06
GAP43 growth associated protein 43 1.06
NSG1 neuron specific gene family member 1 1.06
DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A 1.059
S100B S100 calcium binding protein B 1.058
PPP1R9A protein phosphatase 1, regulatory subunit 9A 1.056
DEFB124 defensin, beta 124 1.055
WDFY3 WD repeat and FYVE domain containing 3 1.055
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant 1.054
CCND2 cyclin D2 1.053
PLXNA1 plexin A1 1.05
PTK2 protein tyrosine kinase 2 1.049
NEFH neurofilament, heavy polypeptide 1.049
CXCL12 chemokine (C-X-C motif) ligand 12 1.048
YWHAH tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta 1.045
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa) 1.045
SMAD9 SMAD family member 9 1.044
MOCS1 molybdenum cofactor synthesis 1 1.041
LOX lysyl oxidase 1.039
ORC4 origin recognition complex, subunit 4 1.039
TUBGCP5 tubulin, gamma complex associated protein 5 1.038
CEP290 centrosomal protein 290kDa 1.038
DPAGT1 dolichyl-phosphate (UDP-N-acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase) 1.038
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta) 1.038
PPIL1 peptidylprolyl isomerase (cyclophilin)-like 1 1.036
OTX1 orthodenticle homeobox 1 1.035
DLX6 distal-less homeobox 6 1.035
SEMA6A sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A 1.033
CAMK2A calcium/calmodulin-dependent protein kinase II alpha 1.033
CAPN2 calpain 2, (m/II) large subunit 1.032
MAPK3 mitogen-activated protein kinase 3 1.032
MARF1 meiosis regulator and mRNA stability factor 1 1.032
SP8 Sp8 transcription factor 1.031
OCRL oculocerebrorenal syndrome of Lowe 1.031
ZIC4 Zic family member 4 1.03
APOE apolipoprotein E 1.03
DIAPH1 diaphanous-related formin 1 1.03
ZNF804A zinc finger protein 804A 1.03
H2BC21 H2B clustered histone 21 1.029
TOE1 target of EGR1, member 1 (nuclear) 1.029
EFNB1 ephrin-B1 1.029
CXCR4 chemokine (C-X-C motif) receptor 4 1.027
SGCA sarcoglycan, alpha (50kDa dystrophin-associated glycoprotein) 1.026
CAPZA2 capping protein (actin filament) muscle Z-line, alpha 2 1.024
DCDC2B doublecortin domain containing 2B 1.024
INPP5K inositol polyphosphate-5-phosphatase K 1.022
CAMSAP3 calmodulin regulated spectrin-associated protein family, member 3 1.022
MAP3K4 mitogen-activated protein kinase kinase kinase 4 1.022
VPS72 vacuolar protein sorting 72 homolog (S. cerevisiae) 1.022
EMC1 ER membrane protein complex subunit 1 1.022
FSCN1 fascin actin-bundling protein 1 1.021
KIRREL3 kin of IRRE like 3 (Drosophila) 1.019
POU5F1 POU class 5 homeobox 1 1.018
HCLS1 hematopoietic cell-specific Lyn substrate 1 1.018
PLEKHM1 pleckstrin homology domain containing, family M (with RUN domain) member 1 1.018
ZNF674 zinc finger protein 674 1.018
DPY19L1 dpy-19-like 1 (C. elegans) 1.017
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B 1.017
POU1F1 POU class 1 homeobox 1 1.014
PHOX2B paired-like homeobox 2b 1.014
CNTN4 contactin 4 1.014
NOVA2 neuro-oncological ventral antigen 2 1.012
ADGRL1 adhesion G protein-coupled receptor L1 1.012
SCRIB scribbled planar cell polarity protein 1.012
GABRD gamma-aminobutyric acid (GABA) A receptor, delta 1.011
CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family) 1.011
LNX1 ligand of numb-protein X 1, E3 ubiquitin protein ligase 1.011
PRTG protogenin 1.01
CCDC63 coiled-coil domain containing 63 1.01
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 1.009
TTLL11 tubulin tyrosine ligase-like family member 11 1.009
RMND5B required for meiotic nuclear division 5 homolog B (S. cerevisiae) 1.008
FGF9 fibroblast growth factor 9 1.008
TTLL1 tubulin tyrosine ligase-like family member 1 1.008
USP6NL USP6 N-terminal like 1.008
VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2) 1.007
SNCA synuclein, alpha (non A4 component of amyloid precursor) 1.007
TTC21B tetratricopeptide repeat domain 21B 1.007
CEP97 centrosomal protein 97kDa 1.007
DOCK1 dedicator of cytokinesis 1 1.007
TBL1X transducin (beta)-like 1X-linked 1.007
TUBG2 tubulin, gamma 2 1.006
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific) 1.005
NINL ninein-like 1.005
TMX1 thioredoxin-related transmembrane protein 1 1.005
POLG polymerase (DNA directed), gamma 1.005
C17ORF78 chromosome 17 open reading frame 78 1.004
MEMO1 mediator of cell motility 1 1.004
CTTN cortactin 1.004
COL4A2 collagen, type IV, alpha 2 1.002
CCDC88C coiled-coil domain containing 88C 1.001
FGF22 fibroblast growth factor 22 1.001