Liver Cirrhosis, Alcoholic Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
External Link https://www.disgenet.org/browser/0/1/0/C0023891
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Genes

108 genes associated with the disease Liver Cirrhosis, Alcoholic in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ACE angiotensin I converting enzyme
ACTB actin, beta
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
ADH1C alcohol dehydrogenase 1C (class I), gamma polypeptide
ADH4 alcohol dehydrogenase 4 (class II), pi polypeptide
ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide
AFM afamin
AKR1A1 aldo-keto reductase family 1, member A1 (aldehyde reductase)
ALB albumin
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
APOE apolipoprotein E
ARG1 arginase 1
ARSH arylsulfatase family, member H
AVP arginine vasopressin
BCL2 B-cell CLL/lymphoma 2
CALCOCO2 calcium binding and coiled-coil domain 2
CAT catalase
CAV1 caveolin 1, caveolae protein, 22kDa
CCL4 chemokine (C-C motif) ligand 4
CCL4L1 chemokine (C-C motif) ligand 4-like 1
CCL4L2 chemokine (C-C motif) ligand 4-like 2
CD14 CD14 molecule
CEL carboxyl ester lipase
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
COL3A1 collagen, type III, alpha 1
CSTB cystatin B (stefin B)
CTLA4 cytotoxic T-lymphocyte-associated protein 4
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
CXCL8 chemokine (C-X-C motif) ligand 8
CYBB cytochrome b-245, beta polypeptide
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1
CYP4A11 cytochrome P450, family 4, subfamily A, polypeptide 11
ENG endoglin
ENHO energy homeostasis associated
FAS Fas cell surface death receptor
FGF19 fibroblast growth factor 19
GABPA GA binding protein transcription factor, alpha subunit 60kDa
GABRG2 gamma-aminobutyric acid (GABA) A receptor, gamma 2
GDF15 growth differentiation factor 15
GGT1 gamma-glutamyltransferase 1
GGTLC3 gamma-glutamyltransferase light chain 3
GLUL glutamate-ammonia ligase
GPC3 glypican 3
GPT glutamic-pyruvate transaminase (alanine aminotransferase)
GPX1 glutathione peroxidase 1
GRB2 growth factor receptor-bound protein 2
GSTM1 glutathione S-transferase mu 1
GSTP1 glutathione S-transferase pi 1
GSTT1 glutathione S-transferase theta 1
HFE hemochromatosis
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HLA-A major histocompatibility complex, class I, A
HLA-B major histocompatibility complex, class I, B
IFNG interferon, gamma
IL10 interleukin 10
IL1B interleukin 1, beta
IL1RN interleukin 1 receptor antagonist
IL2 interleukin 2
IL6 interleukin 6
INSRR insulin receptor-related receptor
LMNA lamin A/C
MAT1A methionine adenosyltransferase I, alpha
MBOAT7 membrane bound O-acyltransferase domain containing 7
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MMP13 matrix metallopeptidase 13
MMP2 matrix metallopeptidase 2
MPO myeloperoxidase
MSC musculin
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
NAT2 N-acetyltransferase 2 (arylamine N-acetyltransferase)
NCAN neurocan
NFE2L2 nuclear factor, erythroid 2-like 2
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NOS3 nitric oxide synthase 3 (endothelial cell)
NQO1 NAD(P)H dehydrogenase, quinone 1
PIAS3 protein inhibitor of activated STAT, 3
PLAU plasminogen activator, urokinase
PNPLA3 patatin-like phospholipase domain containing 3
PPARG peroxisome proliferator-activated receptor gamma
PPP1R16B protein phosphatase 1, regulatory subunit 16B
RARRES2 retinoic acid receptor responder (tazarotene induced) 2
RASGRF2 Ras protein-specific guanine nucleotide-releasing factor 2
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
RIPK3 receptor-interacting serine-threonine kinase 3
SELE selectin E
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3
SERPINB4 serpin peptidase inhibitor, clade B (ovalbumin), member 4
SLC17A5 solute carrier family 17 (acidic sugar transporter), member 5
SLC1A2 solute carrier family 1 (glial high affinity glutamate transporter), member 2
SMAD3 SMAD family member 3
SOD2 superoxide dismutase 2, mitochondrial
SPHK2 sphingosine kinase 2
ST8SIA4 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
SUGP1 SURP and G patch domain containing 1
TGFB1 transforming growth factor, beta 1
TIMP1 TIMP metallopeptidase inhibitor 1
TLR2 toll-like receptor 2
TLR4 toll-like receptor 4
TM6SF2 transmembrane 6 superfamily member 2
TNF tumor necrosis factor
TP53 tumor protein p53
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1