Liver Failure, Acute Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
External Link https://www.disgenet.org/browser/0/1/0/C0162557
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Genes

267 genes associated with the disease Liver Failure, Acute in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group)
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
ACAD9 acyl-CoA dehydrogenase family, member 9
ACADM acyl-CoA dehydrogenase, C-4 to C-12 straight chain
ACKR3 atypical chemokine receptor 3
ACP3 acid phosphatase 3
AFM afamin
AFP alpha-fetoprotein
AHR aryl hydrocarbon receptor
AHSG alpha-2-HS-glycoprotein
AIM2 absent in melanoma 2
AKT1 v-akt murine thymoma viral oncogene homolog 1
ALAS1 5'-aminolevulinate synthase 1
ALB albumin
ALDOB aldolase B, fructose-bisphosphate
ALPP alkaline phosphatase, placental
APOA5 apolipoprotein A-V
AQP4 aquaporin 4
AR androgen receptor
ARHGEF5 Rho guanine nucleotide exchange factor (GEF) 5
ASRGL1 asparaginase like 1
ATG7 autophagy related 7
ATM ATM serine/threonine kinase
ATP7B ATPase, Cu++ transporting, beta polypeptide
ATRNL1 attractin-like 1
BCHE butyrylcholinesterase
BCL2 B-cell CLL/lymphoma 2
BCL2L11 BCL2-like 11 (apoptosis facilitator)
BECN1 beclin 1, autophagy related
BID BH3 interacting domain death agonist
BRIP1 BRCA1 interacting protein C-terminal helicase 1
BST2 bone marrow stromal cell antigen 2
BTBD8 BTB (POZ) domain containing 8
CACNA1S calcium channel, voltage-dependent, L type, alpha 1S subunit
CASP12 caspase 12 (gene/pseudogene)
CASP3 caspase 3, apoptosis-related cysteine peptidase
CASP8 caspase 8, apoptosis-related cysteine peptidase
CASP9 caspase 9, apoptosis-related cysteine peptidase
CAST calpastatin
CCL2 chemokine (C-C motif) ligand 2
CCL27 chemokine (C-C motif) ligand 27
CCL4 chemokine (C-C motif) ligand 4
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
CD14 CD14 molecule
CD40LG CD40 ligand
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain
CD86 CD86 molecule
CEL carboxyl ester lipase
CGA glycoprotein hormones, alpha polypeptide
COL1A2 collagen, type I, alpha 2
COX2
CRP C-reactive protein, pentraxin-related
CSF3 colony stimulating factor 3 (granulocyte)
CTLA4 cytotoxic T-lymphocyte-associated protein 4
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CX3CR1 chemokine (C-X3-C motif) receptor 1
CXCL12 chemokine (C-X-C motif) ligand 12
CXCL16 chemokine (C-X-C motif) ligand 16
CXCL8 chemokine (C-X-C motif) ligand 8
CXCR3 chemokine (C-X-C motif) receptor 3
CYC1 cytochrome c-1
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4
CYSLTR1 cysteinyl leukotriene receptor 1
DCTN4 dynactin 4 (p62)
DDIT3 DNA-damage-inducible transcript 3
DGUOK deoxyguanosine kinase
DHDDS dehydrodolichyl diphosphate synthase
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3
ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1
ERO1A endoplasmic reticulum oxidoreductase 1 alpha
ESR1 estrogen receptor 1
EVA1A eva-1 homolog A (C. elegans)
EXOSC3 exosome component 3
F2 coagulation factor II (thrombin)
F5 coagulation factor V (proaccelerin, labile factor)
FABP1 fatty acid binding protein 1, liver
FABP7 fatty acid binding protein 7, brain
FAH fumarylacetoacetate hydrolase (fumarylacetoacetase)
FAS Fas cell surface death receptor
FASLG Fas ligand (TNF superfamily, member 6)
FBP1 fructose-1,6-bisphosphatase 1
FCGR3A Fc fragment of IgG, low affinity IIIa, receptor (CD16a)
FCGR3B Fc fragment of IgG, low affinity IIIb, receptor (CD16b)
FGA fibrinogen alpha chain
FOXO3 forkhead box O3
FST follistatin
G6PD glucose-6-phosphate dehydrogenase
GABPA GA binding protein transcription factor, alpha subunit 60kDa
GC group-specific component (vitamin D binding protein)
GFAP glial fibrillary acidic protein
GFER growth factor, augmenter of liver regeneration
GFM1 G elongation factor, mitochondrial 1
GORASP1 golgi reassembly stacking protein 1, 65kDa
GPNMB glycoprotein (transmembrane) nmb
GPR35 G protein-coupled receptor 35
GPT glutamic-pyruvate transaminase (alanine aminotransferase)
GSDMD gasdermin D
GSK3B glycogen synthase kinase 3 beta
GTF2A1L general transcription factor IIA, 1-like
GTF2H1 general transcription factor IIH, polypeptide 1, 62kDa
HADH hydroxyacyl-CoA dehydrogenase
HAMP hepcidin antimicrobial peptide
HAVCR1 hepatitis A virus cellular receptor 1
HDAC2 histone deacetylase 2
HDAC6 histone deacetylase 6
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HLA-B major histocompatibility complex, class I, B
HMGB1 high mobility group box 1
HMOX1 heme oxygenase 1
HNF4A hepatocyte nuclear factor 4, alpha
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
HSPA8 heat shock 70kDa protein 8
HSPG2 heparan sulfate proteoglycan 2
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
IFNA1 interferon, alpha 1
IFNA13 interferon, alpha 13
IFNB1 interferon, beta 1, fibroblast
IFNG interferon, gamma
IFNL3 interferon, lambda 3
IKZF1 IKAROS family zinc finger 1 (Ikaros)
IL10 interleukin 10
IL18 interleukin 18
IL1A interleukin 1, alpha
IL1B interleukin 1, beta
IL1R1 interleukin 1 receptor, type I
IL1RN interleukin 1 receptor antagonist
IL2 interleukin 2
IL6 interleukin 6
INHBA inhibin, beta A
INS insulin
INS-IGF2 INS-IGF2 readthrough
ITCH itchy E3 ubiquitin protein ligase
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit)
JAK2 Janus kinase 2
KCNJ10 potassium channel, inwardly rectifying subfamily J, member 10
KCTD9 potassium channel tetramerization domain containing 9
KHDRBS1 KH domain containing, RNA binding, signal transduction associated 1
KLF6 Kruppel-like factor 6
KMT2A lysine (K)-specific methyltransferase 2A
KRT18 keratin 18, type I
KRT8 keratin 8, type II
LARS1 leucyl-tRNA synthetase 1
LMLN leishmanolysin-like (metallopeptidase M8 family)
LONP1 lon peptidase 1, mitochondrial
LTC4S leukotriene C4 synthase
MAP3K7 mitogen-activated protein kinase kinase kinase 7
MAPK8 mitogen-activated protein kinase 8
MARS1 methionyl-tRNA synthetase 1
MEFV Mediterranean fever
MET MET proto-oncogene, receptor tyrosine kinase
MFN2 mitofusin 2
MPO myeloperoxidase
MPV17 MpV17 mitochondrial inner membrane protein
MSC musculin
MSMB microseminoprotein, beta-
MST1 macrophage stimulating 1
MYD88 myeloid differentiation primary response 88
NAT10 N-acetyltransferase 10 (GCN5-related)
NBAS neuroblastoma amplified sequence
NFE2L2 nuclear factor, erythroid 2-like 2
NLRP3 NLR family, pyrin domain containing 3
NOS2 nitric oxide synthase 2, inducible
NOS3 nitric oxide synthase 3 (endothelial cell)
NT5E 5'-nucleotidase, ecto (CD73)
NUP62 nucleoporin 62kDa
OCLN occludin
OPN1SW opsin 1 (cone pigments), short-wave-sensitive
OTC ornithine carbamoyltransferase
PANX1 pannexin 1
PARP9 poly (ADP-ribose) polymerase family, member 9
PDLIM3 PDZ and LIM domain 3
PEBP1 phosphatidylethanolamine binding protein 1
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
PIK3IP1 phosphoinositide-3-kinase interacting protein 1
PIM1 Pim-1 proto-oncogene, serine/threonine kinase
PIM3 Pim-3 proto-oncogene, serine/threonine kinase
POLG polymerase (DNA directed), gamma
POLG2 polymerase (DNA directed), gamma 2, accessory subunit
POMC proopiomelanocortin
PORCN porcupine homolog (Drosophila)
PPARA peroxisome proliferator-activated receptor alpha
PPARGC1B peroxisome proliferator-activated receptor gamma, coactivator 1 beta
PPIG peptidylprolyl isomerase G (cyclophilin G)
PPP1R11 protein phosphatase 1, regulatory (inhibitor) subunit 11
PPP2R5A protein phosphatase 2, regulatory subunit B', alpha
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit
PRKAA2 protein kinase, AMP-activated, alpha 2 catalytic subunit
PRKAB1 protein kinase, AMP-activated, beta 1 non-catalytic subunit
PTAFR platelet-activating factor receptor
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
RBP4 retinol binding protein 4, plasma
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
RGN regucalcin
RHD Rh blood group, D antigen
RINT1 RAD50 interactor 1
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1
RRM2B ribonucleotide reductase M2 B (TP53 inducible)
RYR1 ryanodine receptor 1 (skeletal)
S100A10 S100 calcium binding protein A10
S100A12 S100 calcium binding protein A12
SCO1 SCO1 cytochrome c oxidase assembly protein
SCYL1 SCY1-like 1 (S. cerevisiae)
SDC1 syndecan 1
SERAC1 serine active site containing 1
SERPINC1 serpin peptidase inhibitor, clade C (antithrombin), member 1
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SERPINF2 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2
SESN2 sestrin 2
SHANK3 SH3 and multiple ankyrin repeat domains 3
SIGLEC9 sialic acid binding Ig-like lectin 9
SIRT1 sirtuin 1
SIRT2 sirtuin 2
SLA2 Src-like-adaptor 2
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2
SLC17A5 solute carrier family 17 (acidic sugar transporter), member 5
SLC1A2 solute carrier family 1 (glial high affinity glutamate transporter), member 2
SLC25A37 solute carrier family 25 (mitochondrial iron transporter), member 37
SLC27A5 solute carrier family 27 (fatty acid transporter), member 5
SLC6A12 solute carrier family 6 (neurotransmitter transporter), member 12
SLPI secretory leukocyte peptidase inhibitor
SOAT1 sterol O-acyltransferase 1
SOCS1 suppressor of cytokine signaling 1
SQSTM1 sequestosome 1
STAR steroidogenic acute regulatory protein
STAT1 signal transducer and activator of transcription 1, 91kDa
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STON1 stonin 1
STON1-GTF2A1L STON1-GTF2A1L readthrough
STX18 syntaxin 18
SYT1 synaptotagmin I
TBC1D9 TBC1 domain family, member 9 (with GRAM domain)
TCF4 transcription factor 4
TFEB transcription factor EB
TGFB1 transforming growth factor, beta 1
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
THBD thrombomodulin
THBS1 thrombospondin 1
THPO thrombopoietin
TIMELESS timeless circadian clock
TLR2 toll-like receptor 2
TLR3 toll-like receptor 3
TLR4 toll-like receptor 4
TLR9 toll-like receptor 9
TMPRSS13 transmembrane protease, serine 13
TNF tumor necrosis factor
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TNFAIP6 tumor necrosis factor, alpha-induced protein 6
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b
TP53 tumor protein p53
TRMU tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase
TXN thioredoxin
TXNIP thioredoxin interacting protein
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)
UGT2B7 UDP glucuronosyltransferase 2 family, polypeptide B7
VIP vasoactive intestinal peptide
VPS13A vacuolar protein sorting 13 homolog A (S. cerevisiae)
VWF von Willebrand factor
WNK1 WNK lysine deficient protein kinase 1
YAP1 Yes-associated protein 1