Locally Advanced Breast Cancer Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
External Link https://www.disgenet.org/browser/0/1/0/C3495949
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Genes

67 genes associated with the disease Locally Advanced Breast Cancer in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
ADRB2 adrenoceptor beta 2, surface
ARHGEF7 Rho guanine nucleotide exchange factor (GEF) 7
ASCC1 activating signal cointegrator 1 complex subunit 1
ATM ATM serine/threonine kinase
BAG1 BCL2-associated athanogene
BBC3 BCL2 binding component 3
BCL2 B-cell CLL/lymphoma 2
CA9 carbonic anhydrase IX
CASP3 caspase 3, apoptosis-related cysteine peptidase
CCL5 chemokine (C-C motif) ligand 5
CD274 CD274 molecule
CD40 CD40 molecule, TNF receptor superfamily member 5
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CXCR4 chemokine (C-X-C motif) receptor 4
CXXC5 CXXC finger protein 5
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1
DHCR24 24-dehydrocholesterol reductase
EGF epidermal growth factor
EGFR epidermal growth factor receptor
ERBB2 erb-b2 receptor tyrosine kinase 2
ESR1 estrogen receptor 1
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit
FANCC Fanconi anemia, complementation group C
GHR growth hormone receptor
GSTM1 glutathione S-transferase mu 1
GSTP1 glutathione S-transferase pi 1
GSTT1 glutathione S-transferase theta 1
HPGDS hematopoietic prostaglandin D synthase
IL18 interleukin 18
ITK IL2-inducible T-cell kinase
KRT19 keratin 19, type I
LRP1 low density lipoprotein receptor-related protein 1
MAGEA4 melanoma antigen family A4
MAP1LC3B microtubule-associated protein 1 light chain 3 beta
MIB1 mindbomb E3 ubiquitin protein ligase 1
MLH1 mutL homolog 1
MVP major vault protein
NEU1 sialidase 1 (lysosomal sialidase)
NEURL1 neuralized E3 ubiquitin protein ligase 1
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NLRP1 NLR family, pyrin domain containing 1
NRP1 neuropilin 1
PGR progesterone receptor
PTEN phosphatase and tensin homolog
PTPRA protein tyrosine phosphatase, receptor type, A
REST RE1-silencing transcription factor
RMDN1 regulator of microtubule dynamics 1
RMDN2 regulator of microtubule dynamics 2
RMDN3 regulator of microtubule dynamics 3
RPSA ribosomal protein SA
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
SLC22A3 solute carrier family 22 (organic cation transporter), member 3
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1
SPINT1 serine peptidase inhibitor, Kunitz type 1
ST14 suppression of tumorigenicity 14 (colon carcinoma)
SYBU syntabulin (syntaxin-interacting)
TBC1D9 TBC1 domain family, member 9 (with GRAM domain)
TOP2A topoisomerase (DNA) II alpha 170kDa
TP53 tumor protein p53
VEGFA vascular endothelial growth factor A
WIF1 WNT inhibitory factor 1
WISP3 WNT1 inducible signaling pathway protein 3
XK X-linked Kx blood group