| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Lonafarnib perturbation in A-172 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Lonafarnib_A-172 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AHNAK | AHNAK nucleoprotein | 0.156407 |
| PODXL | podocalyxin-like | 0.155095 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.140736 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.136346 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.101281 |
| CDH13 | cadherin 13 | 0.0929193 |
| NAV1 | neuron navigator 1 | 0.0878674 |
| CD44 | CD44 molecule (Indian blood group) | 0.0699369 |
| SLC39A11 | solute carrier family 39, member 11 | 0.0640895 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0609677 |
| FLNB | filamin B, beta | 0.0608333 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0596246 |
| COL5A1 | collagen, type V, alpha 1 | 0.0590293 |
| RUNX1 | runt-related transcription factor 1 | 0.0570221 |
| FSTL1 | follistatin-like 1 | 0.0510567 |
| NDRG1 | N-myc downstream regulated 1 | 0.0496643 |
| CANX | calnexin | 0.0494222 |
| THBS2 | thrombospondin 2 | 0.0487249 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0480216 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0480013 |
| HDAC9 | histone deacetylase 9 | 0.0477281 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | 0.0473782 |
| MAP1B | microtubule-associated protein 1B | 0.0471328 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0469213 |
| ANXA2 | annexin A2 | 0.0461276 |
| EGFR | epidermal growth factor receptor | 0.0454126 |
| FLNA | filamin A, alpha | 0.0431845 |
| DST | dystonin | 0.0429388 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.041498 |
| HS3ST3A1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1 | 0.0408671 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0407381 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0397958 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.0391457 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0380507 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0378548 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | 0.0377084 |
| SEPTIN9 | septin 9 | 0.0372675 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0365584 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0361392 |
| EFNA5 | ephrin-A5 | 0.0356294 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0352749 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0348553 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.034077 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | 0.0338367 |
| GLIS3 | GLIS family zinc finger 3 | 0.0333483 |
| DPYSL2 | dihydropyrimidinase-like 2 | 0.0332688 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0328799 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0328024 |
| ASPH | aspartate beta-hydroxylase | 0.032041 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0318221 |
| NAV2 | neuron navigator 2 | 0.0311925 |
| APP | amyloid beta (A4) precursor protein | 0.0307679 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0305978 |
| RHOBTB3 | Rho-related BTB domain containing 3 | 0.0305694 |
| PRELID2 | PRELI domain containing 2 | 0.0300057 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0297152 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0294511 |
| LOXL2 | lysyl oxidase-like 2 | 0.0293774 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0290689 |
| RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 | 0.0290571 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.028616 |
| MYOF | myoferlin | 0.0285518 |
| TPM3 | tropomyosin 3 | 0.0279877 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0278127 |
| SMYD3 | SET and MYND domain containing 3 | 0.0277764 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | 0.0277312 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0275078 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0271726 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 | 0.0271373 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0269142 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0267382 |
| TMSB4X | thymosin beta 4, X-linked | 0.0265016 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0263498 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0262422 |
| FNIP1 | folliculin interacting protein 1 | 0.0261334 |
| MB21D2 | Mab-21 domain containing 2 | 0.0258612 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0253233 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0252633 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0247853 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0247592 |
| CAPN2 | calpain 2, (m/II) large subunit | 0.0236624 |
| CSTB | cystatin B (stefin B) | 0.0234494 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0232897 |
| OR51B5 | olfactory receptor, family 51, subfamily B, member 5 | 0.0228334 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0225386 |
| COL3A1 | collagen, type III, alpha 1 | 0.0219737 |
| OGA | O-GlcNAcase | 0.0219538 |
| ZNF217 | zinc finger protein 217 | 0.0219237 |
| DCLK2 | doublecortin-like kinase 2 | 0.0218749 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.02184 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.0216195 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0215505 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | 0.0213792 |
| PLEC | plectin | 0.0212609 |
| ANO6 | anoctamin 6 | 0.0210904 |
| TENM3 | teneurin transmembrane protein 3 | 0.0209969 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0208635 |
| PRKAG2 | protein kinase, AMP-activated, gamma 2 non-catalytic subunit | 0.020603 |
| TRAM2 | translocation associated membrane protein 2 | 0.020414 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0204126 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.0772009 |
| MT2A | metallothionein 2A | -0.0507976 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0289094 |
| FTL | ferritin, light polypeptide | -0.0261015 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0245077 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0244508 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0241751 |
| FBN1 | fibrillin 1 | -0.0239751 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0225395 |
| COL1A2 | collagen, type I, alpha 2 | -0.0224309 |
| B2M | beta-2-microglobulin | -0.0208402 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0199866 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0191918 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0190886 |
| PTMA | prothymosin, alpha | -0.0186442 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0184885 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0176951 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0169912 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0138959 |
| WTAP | Wilms tumor 1 associated protein | -0.0138542 |
| RPS6 | ribosomal protein S6 | -0.0138347 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0137525 |
| MX2 | MX dynamin-like GTPase 2 | -0.013607 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0131183 |
| UBC | ubiquitin C | -0.0128112 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0128002 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0115803 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0115407 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0114774 |
| OASL | 2'-5'-oligoadenylate synthetase-like | -0.0112385 |
| LPCAT2 | lysophosphatidylcholine acyltransferase 2 | -0.0111613 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0109203 |
| IER3 | immediate early response 3 | -0.0107185 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0105788 |
| CCL5 | chemokine (C-C motif) ligand 5 | -0.0102171 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0101872 |
| S100A9 | S100 calcium binding protein A9 | -0.0101552 |
| S100A6 | S100 calcium binding protein A6 | -0.0100954 |
| RPL35A | ribosomal protein L35a | -0.00935679 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.00933094 |
| TAGLN2 | transgelin 2 | -0.00930671 |
| RIGI | RNA sensor RIG-I | -0.00930091 |
| DIRAS3 | DIRAS family, GTP-binding RAS-like 3 | -0.00918086 |
| ADM | adrenomedullin | -0.00885433 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.00885343 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | -0.00872373 |
| RPLP2 | ribosomal protein, large, P2 | -0.00860003 |
| ARL15 | ADP-ribosylation factor-like 15 | -0.00857853 |
| IFI44 | interferon-induced protein 44 | -0.00825618 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0082043 |
| TPM1 | tropomyosin 1 (alpha) | -0.00811596 |
| RPS19 | ribosomal protein S19 | -0.00800595 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.00791209 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | -0.00777458 |
| FN1 | fibronectin 1 | -0.00770417 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | -0.00755371 |
| SH3BGRL3 | SH3 domain binding glutamate-rich protein like 3 | -0.00745407 |
| MYADM | myeloid-associated differentiation marker | -0.00740895 |
| ITM2B | integral membrane protein 2B | -0.00722546 |
| HERC5 | HECT and RLD domain containing E3 ubiquitin protein ligase 5 | -0.00721548 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.00716818 |
| POTEF | POTE ankyrin domain family, member F | -0.00711031 |
| CLU | clusterin | -0.006949 |
| IL32 | interleukin 32 | -0.00689331 |
| COL6A1 | collagen, type VI, alpha 1 | -0.00687863 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.00686438 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.00679028 |
| TAPBP | TAP binding protein (tapasin) | -0.00678904 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.00672526 |
| CNNM2 | cyclin and CBS domain divalent metal cation transport mediator 2 | -0.00667564 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.00661384 |
| KDM6A | lysine (K)-specific demethylase 6A | -0.00652053 |
| GNAS | GNAS complex locus | -0.00646793 |
| HMGA1 | high mobility group AT-hook 1 | -0.0064301 |
| SLC22A4 | solute carrier family 22 (organic cation/zwitterion transporter), member 4 | -0.00640774 |
| NUPR1 | nuclear protein, transcriptional regulator, 1 | -0.00635134 |
| TUBB2A | tubulin, beta 2A class IIa | -0.00633513 |
| FAM162A | family with sequence similarity 162, member A | -0.00628134 |
| TNIP1 | TNFAIP3 interacting protein 1 | -0.00620895 |
| DDIT3 | DNA-damage-inducible transcript 3 | -0.00613904 |
| FADS2 | fatty acid desaturase 2 | -0.00611531 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.00610965 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0060943 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 | -0.0060895 |
| TMOD1 | tropomodulin 1 | -0.00608784 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.00607614 |
| RPL36 | ribosomal protein L36 | -0.0059851 |
| SKIC3 | SKI3 subunit of superkiller complex | -0.00594416 |
| HMGB1 | high mobility group box 1 | -0.00593038 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | -0.0058673 |
| PABPN1 | poly(A) binding protein, nuclear 1 | -0.00577912 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | -0.00575524 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.00571719 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.00571536 |
| CST3 | cystatin C | -0.00571246 |
| IRF1 | interferon regulatory factor 1 | -0.00565522 |
| NFIX | nuclear factor I/X (CCAAT-binding transcription factor) | -0.00558148 |
| DPYSL3 | dihydropyrimidinase-like 3 | -0.00557638 |
| ECM1 | extracellular matrix protein 1 | -0.00555485 |
| RPLP1 | ribosomal protein, large, P1 | -0.00553998 |
