| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Lonafarnib perturbation in CHP-212 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Lonafarnib_CHP-212 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IGF2 | insulin-like growth factor 2 | 0.15387 |
| TLE4 | transducin-like enhancer of split 4 | 0.0633901 |
| MEIS2 | Meis homeobox 2 | 0.051627 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0511492 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0465699 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0462643 |
| RPS6 | ribosomal protein S6 | 0.0427567 |
| RPS12 | ribosomal protein S12 | 0.0426032 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0423131 |
| TPST1 | tyrosylprotein sulfotransferase 1 | 0.0396988 |
| RACK1 | receptor for activated C kinase 1 | 0.0374697 |
| FMN1 | formin 1 | 0.0374673 |
| RPL37A | ribosomal protein L37a | 0.0369753 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | 0.0365364 |
| B2M | beta-2-microglobulin | 0.0364609 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0361577 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0355846 |
| RPS27A | ribosomal protein S27a | 0.0335456 |
| SLIT2 | slit homolog 2 (Drosophila) | 0.0320969 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0314244 |
| ADAMTS9 | ADAM metallopeptidase with thrombospondin type 1 motif, 9 | 0.0312791 |
| KLHL13 | kelch-like family member 13 | 0.0306654 |
| PCBP2 | poly(rC) binding protein 2 | 0.0305797 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0298235 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.029061 |
| RPL35A | ribosomal protein L35a | 0.0286471 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | 0.0285969 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0284914 |
| SMAD3 | SMAD family member 3 | 0.0278929 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0277313 |
| MYCN | v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog | 0.027354 |
| GLCCI1 | glucocorticoid induced 1 | 0.0262463 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.0258932 |
| RPS25 | ribosomal protein S25 | 0.0256814 |
| ADAR | adenosine deaminase, RNA-specific | 0.0253794 |
| BPTF | bromodomain PHD finger transcription factor | 0.0253237 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0251397 |
| AOPEP | aminopeptidase O (putative) | 0.025088 |
| COX16 | COX16 cytochrome c oxidase assembly homolog (S. cerevisiae) | 0.0248471 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0248364 |
| RPL13A | ribosomal protein L13a | 0.0246083 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | 0.0245513 |
| PELO | pelota homolog (Drosophila) | 0.024388 |
| AHNAK | AHNAK nucleoprotein | 0.0243256 |
| RPS3 | ribosomal protein S3 | 0.024287 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0242627 |
| VMP1 | vacuole membrane protein 1 | 0.0241523 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0240018 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0237196 |
| ANXA2 | annexin A2 | 0.023548 |
| FLNA | filamin A, alpha | 0.023493 |
| ZNF292 | zinc finger protein 292 | 0.0230827 |
| FERMT2 | fermitin family member 2 | 0.023062 |
| RPL26 | ribosomal protein L26 | 0.0229648 |
| TRPS1 | trichorhinophalangeal syndrome I | 0.0227143 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0223649 |
| RPS8 | ribosomal protein S8 | 0.0221966 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | 0.0218257 |
| BRD4 | bromodomain containing 4 | 0.0215402 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | 0.0213826 |
| TCF12 | transcription factor 12 | 0.021381 |
| RPL9 | ribosomal protein L9 | 0.0212365 |
| TPR | translocated promoter region, nuclear basket protein | 0.0210427 |
| DCAF7 | DDB1 and CUL4 associated factor 7 | 0.0209326 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0207756 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | 0.0206891 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0204811 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0202517 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | 0.020219 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0201183 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0197703 |
| ITGA1 | integrin, alpha 1 | 0.0197542 |
| COL1A1 | collagen, type I, alpha 1 | 0.0197278 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | 0.0196653 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | 0.0195968 |
| RPS2 | ribosomal protein S2 | 0.0195536 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.019329 |
| KLF6 | Kruppel-like factor 6 | 0.0190886 |
| SON | SON DNA binding protein | 0.0189788 |
| KAT6A | K(lysine) acetyltransferase 6A | 0.0189222 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0188654 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0188042 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0187661 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0187169 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0186013 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0185987 |
| FUS | FUS RNA binding protein | 0.0185622 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0185402 |
| CCNL1 | cyclin L1 | 0.0185177 |
| RPL19 | ribosomal protein L19 | 0.0185173 |
| PDE10A | phosphodiesterase 10A | 0.0184512 |
| RPS13 | ribosomal protein S13 | 0.018391 |
| POTEF | POTE ankyrin domain family, member F | 0.0183368 |
| RPL5 | ribosomal protein L5 | 0.0182921 |
| SET | SET nuclear proto-oncogene | 0.0180787 |
| YBX1 | Y box binding protein 1 | 0.0179296 |
| CUL3 | cullin 3 | 0.0178893 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0178802 |
| RBM25 | RNA binding motif protein 25 | 0.0178489 |
| RPL36 | ribosomal protein L36 | 0.017817 |
| Symbol | Name | Standardized Value |
|---|---|---|
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | -0.126314 |
| PTMA | prothymosin, alpha | -0.0929159 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0691331 |
| VCL | vinculin | -0.0638853 |
| LSAMP | limbic system-associated membrane protein | -0.0529981 |
| VIM | vimentin | -0.0517156 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0481567 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0470809 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | -0.0466062 |
| MEF2A | myocyte enhancer factor 2A | -0.0376179 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.0331295 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | -0.0318807 |
| MSI2 | musashi RNA-binding protein 2 | -0.0293825 |
| GPC6 | glypican 6 | -0.0265856 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0251508 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0239827 |
| ATRNL1 | attractin-like 1 | -0.0238023 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0237284 |
| SLC8A1 | solute carrier family 8 (sodium/calcium exchanger), member 1 | -0.0233427 |
| GPC5 | glypican 5 | -0.0233276 |
| DTNA | dystrobrevin, alpha | -0.0232129 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.0228711 |
| CNTN4 | contactin 4 | -0.0223522 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0216846 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0214342 |
| HMGA2 | high mobility group AT-hook 2 | -0.0213716 |
| NPR2 | natriuretic peptide receptor 2 | -0.0213084 |
| CDH13 | cadherin 13 | -0.0211293 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0207606 |
| RAI14 | retinoic acid induced 14 | -0.0203352 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0193605 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0192775 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | -0.0189423 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0181977 |
| MORF4L1 | mortality factor 4 like 1 | -0.0181907 |
| PRKCA | protein kinase C, alpha | -0.0179521 |
| RPL31 | ribosomal protein L31 | -0.0177939 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0177229 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0176728 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0176072 |
| IER3 | immediate early response 3 | -0.0175749 |
| SCG2 | secretogranin II | -0.0175716 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0169495 |
| SAMD5 | sterile alpha motif domain containing 5 | -0.0169297 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0168084 |
| LDHA | lactate dehydrogenase A | -0.0166562 |
| PARD3 | par-3 family cell polarity regulator | -0.0165408 |
| FN1 | fibronectin 1 | -0.0164063 |
| TMSB10 | thymosin beta 10 | -0.0162169 |
| CUX1 | cut-like homeobox 1 | -0.0161373 |
| ST6GALNAC3 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3 | -0.0161363 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.015823 |
| ZC3H11A | zinc finger CCCH-type containing 11A | -0.015814 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | -0.0157738 |
| CFDP1 | craniofacial development protein 1 | -0.0155855 |
| ATM | ATM serine/threonine kinase | -0.0155779 |
| ARCN1 | archain 1 | -0.0154327 |
| SYT1 | synaptotagmin I | -0.0153693 |
| CA12 | carbonic anhydrase XII | -0.0152691 |
| MORF4L2 | mortality factor 4 like 2 | -0.0151868 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0151772 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0151602 |
| HIP1 | huntingtin interacting protein 1 | -0.0150976 |
| RBMX | RNA binding motif protein, X-linked | -0.0149581 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0149333 |
| CANX | calnexin | -0.0148998 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0147385 |
| PDZRN3 | PDZ domain containing ring finger 3 | -0.0146602 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0146401 |
| WDFY2 | WD repeat and FYVE domain containing 2 | -0.014473 |
| HSPA13 | heat shock protein 70kDa family, member 13 | -0.0141981 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0141764 |
| OXR1 | oxidation resistance 1 | -0.0141657 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.0140793 |
| SRP54 | signal recognition particle 54kDa | -0.0140746 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0140606 |
| CPNE8 | copine VIII | -0.0140269 |
| RANBP17 | RAN binding protein 17 | -0.0139399 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | -0.013893 |
| IGFBP4 | insulin-like growth factor binding protein 4 | -0.0138778 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | -0.0138729 |
| SETD5 | SET domain containing 5 | -0.0138135 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0137641 |
| NRG1 | neuregulin 1 | -0.0137352 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0137236 |
| NAV2 | neuron navigator 2 | -0.0135935 |
| PRKG1 | protein kinase, cGMP-dependent, type I | -0.0134635 |
| UNC5C | unc-5 homolog C (C. elegans) | -0.0134611 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0132421 |
| SSBP2 | single-stranded DNA binding protein 2 | -0.0131104 |
| HM13 | histocompatibility (minor) 13 | -0.0130886 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0130827 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0130237 |
| RBFOX2 | RNA binding protein, fox-1 homolog (C. elegans) 2 | -0.012903 |
| XPR1 | xenotropic and polytropic retrovirus receptor 1 | -0.0128981 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | -0.0128741 |
| NBEA | neurobeachin | -0.0128219 |
| PLCB4 | phospholipase C, beta 4 | -0.0126355 |
| CACNA1C | calcium channel, voltage-dependent, L type, alpha 1C subunit | -0.0125009 |
| COL18A1 | collagen, type XVIII, alpha 1 | -0.0124823 |
