| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Lonafarnib perturbation in COLO 205 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Lonafarnib_COLO 205 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0827977 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | 0.0816234 |
| SMAD3 | SMAD family member 3 | 0.0806372 |
| LMO7 | LIM domain 7 | 0.074158 |
| LCN2 | lipocalin 2 | 0.0652548 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | 0.0517397 |
| EXT1 | exostosin glycosyltransferase 1 | 0.049751 |
| ANXA2 | annexin A2 | 0.0482908 |
| EFNB2 | ephrin-B2 | 0.0457795 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0445558 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0427085 |
| ASPH | aspartate beta-hydroxylase | 0.04158 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0413283 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0408169 |
| MYO1E | myosin IE | 0.0396025 |
| RUNX1 | runt-related transcription factor 1 | 0.0365127 |
| FAT1 | FAT atypical cadherin 1 | 0.0332161 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0322824 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0307425 |
| TJP1 | tight junction protein 1 | 0.0302624 |
| SIPA1L2 | signal-induced proliferation-associated 1 like 2 | 0.0299916 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | 0.0295712 |
| MYO5B | myosin VB | 0.0287345 |
| ANKRD10 | ankyrin repeat domain 10 | 0.0287245 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0266276 |
| B2M | beta-2-microglobulin | 0.0254114 |
| MACC1 | metastasis associated in colon cancer 1 | 0.0251529 |
| STS | steroid sulfatase (microsomal), isozyme S | 0.0250036 |
| MAP7 | microtubule-associated protein 7 | 0.0250004 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0245777 |
| TRERF1 | transcriptional regulating factor 1 | 0.0243664 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.024025 |
| AREG | amphiregulin | 0.0237983 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0235265 |
| ETV6 | ets variant 6 | 0.0234486 |
| IFNGR1 | interferon gamma receptor 1 | 0.0230377 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.0227036 |
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | 0.022555 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | 0.0221888 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0220009 |
| STK24 | serine/threonine kinase 24 | 0.021069 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0206171 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0205042 |
| YAP1 | Yes-associated protein 1 | 0.0204497 |
| ADAR | adenosine deaminase, RNA-specific | 0.0201754 |
| PRELID2 | PRELI domain containing 2 | 0.0200757 |
| SEPTIN9 | septin 9 | 0.0200558 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | 0.0200418 |
| MSI2 | musashi RNA-binding protein 2 | 0.019942 |
| SBF2 | SET binding factor 2 | 0.019835 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.0197759 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | 0.0197475 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.0196699 |
| PLSCR2 | phospholipid scramblase 2 | 0.0193578 |
| C6ORF132 | chromosome 6 open reading frame 132 | 0.0192014 |
| DIAPH1 | diaphanous-related formin 1 | 0.0191387 |
| ELOF1 | elongation factor 1 homolog (S. cerevisiae) | 0.0191271 |
| HKDC1 | hexokinase domain containing 1 | 0.0185054 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | 0.0183156 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0182626 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0182189 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | 0.0179958 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0178784 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0178683 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0174763 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0174057 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0172647 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0172481 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0171788 |
| APP | amyloid beta (A4) precursor protein | 0.0171594 |
| FHIT | fragile histidine triad | 0.0171561 |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) | 0.0171178 |
| EREG | epiregulin | 0.0170324 |
| BCL2L1 | BCL2-like 1 | 0.0166752 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0166619 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | 0.0166145 |
| FHL2 | four and a half LIM domains 2 | 0.016541 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0165339 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0162623 |
| PACSIN2 | protein kinase C and casein kinase substrate in neurons 2 | 0.0162622 |
| SAMD12 | sterile alpha motif domain containing 12 | 0.0161975 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0160042 |
| KYNU | kynureninase | 0.0159969 |
| DIP2B | DIP2 disco-interacting protein 2 homolog B (Drosophila) | 0.0158807 |
| PDZD8 | PDZ domain containing 8 | 0.0157908 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0154236 |
| RND3 | Rho family GTPase 3 | 0.0153026 |
| DUSP10 | dual specificity phosphatase 10 | 0.0151941 |
| DPP4 | dipeptidyl-peptidase 4 | 0.01476 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0147146 |
| ZNF292 | zinc finger protein 292 | 0.0146933 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | 0.0146663 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | 0.0145126 |
| CTSB | cathepsin B | 0.0144109 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0143655 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.0142712 |
| ZHX2 | zinc fingers and homeoboxes 2 | 0.0142142 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0140912 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | 0.014029 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0138359 |
| Symbol | Name | Standardized Value |
|---|---|---|
| LYZ | lysozyme | -0.0451809 |
| EGR1 | early growth response 1 | -0.0408328 |
| PTMA | prothymosin, alpha | -0.0379285 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0349431 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0347275 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0329106 |
| NPSR1 | neuropeptide S receptor 1 | -0.030554 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | -0.0289044 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0267896 |
| EPSTI1 | epithelial stromal interaction 1 (breast) | -0.0260703 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0257467 |
| RIGI | RNA sensor RIG-I | -0.023792 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.022622 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0207951 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.019469 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -0.0184982 |
| NDRG1 | N-myc downstream regulated 1 | -0.0178182 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0170612 |
| MUC20 | mucin 20, cell surface associated | -0.0166927 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) | -0.0166723 |
| PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) | -0.0157531 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | -0.0150722 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0147484 |
| GOLGB1 | golgin B1 | -0.0145339 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0142247 |
| CSTPP1 | centriolar satellite-associated tubulin polyglutamylase complex regulator 1 | -0.0134925 |
| SCARB1 | scavenger receptor class B, member 1 | -0.0132527 |
| JUN | jun proto-oncogene | -0.0130766 |
| DIAPH3 | diaphanous-related formin 3 | -0.0127525 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0126842 |
| SP100 | SP100 nuclear antigen | -0.0124296 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0123767 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.012261 |
| EZR | ezrin | -0.011889 |
| OASL | 2'-5'-oligoadenylate synthetase-like | -0.011667 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.0113868 |
| ADIPOR2 | adiponectin receptor 2 | -0.0113815 |
| MECOM | MDS1 and EVI1 complex locus | -0.0113567 |
| HDLBP | high density lipoprotein binding protein | -0.0112507 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | -0.0111341 |
| CTSD | cathepsin D | -0.0111303 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.011093 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0110756 |
| RAB6A | RAB6A, member RAS oncogene family | -0.0110534 |
| COG6 | component of oligomeric golgi complex 6 | -0.0109664 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0109611 |
| ARF4 | ADP-ribosylation factor 4 | -0.0109005 |
| GRK3 | G protein-coupled receptor kinase 3 | -0.0107077 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0106522 |
| AGR2 | anterior gradient 2 | -0.0106317 |
| SLC44A1 | solute carrier family 44 (choline transporter), member 1 | -0.0106263 |
| H1-0 | H1.0 linker histone | -0.0103903 |
| GOLPH3L | golgi phosphoprotein 3-like | -0.0103747 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -0.0103744 |
| FDPS | farnesyl diphosphate synthase | -0.0102148 |
| IRF1 | interferon regulatory factor 1 | -0.0100904 |
| NT5C3A | 5'-nucleotidase, cytosolic IIIA | -0.0100347 |
| SCFD1 | sec1 family domain containing 1 | -0.00997636 |
| SMC4 | structural maintenance of chromosomes 4 | -0.00993982 |
| SDCBP2 | syndecan binding protein (syntenin) 2 | -0.00989718 |
| PMP22 | peripheral myelin protein 22 | -0.00984756 |
| WASF2 | WAS protein family, member 2 | -0.00982082 |
| PTEN | phosphatase and tensin homolog | -0.00979991 |
| KAT6B | K(lysine) acetyltransferase 6B | -0.00954139 |
| XAF1 | XIAP associated factor 1 | -0.00932103 |
| STARD4 | StAR-related lipid transfer (START) domain containing 4 | -0.00923789 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0091594 |
| TMEM263 | transmembrane protein 263 | -0.00910037 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0090755 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.00905877 |
| APOL6 | apolipoprotein L, 6 | -0.00900403 |
| PDXDC1 | pyridoxal-dependent decarboxylase domain containing 1 | -0.00896309 |
| DDIT3 | DNA-damage-inducible transcript 3 | -0.00891733 |
| HM13 | histocompatibility (minor) 13 | -0.00883544 |
| LGMN | legumain | -0.00881097 |
| ARHGEF38 | Rho guanine nucleotide exchange factor (GEF) 38 | -0.0088025 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.00877792 |
| CANX | calnexin | -0.00877315 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.00873924 |
| GOLGA2 | golgin A2 | -0.00873019 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.00869316 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | -0.00849913 |
| HUNK | hormonally up-regulated Neu-associated kinase | -0.00838222 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.00830521 |
| FOXP1 | forkhead box P1 | -0.00813129 |
| LAP3 | leucine aminopeptidase 3 | -0.00804735 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.00801694 |
| COPA | coatomer protein complex, subunit alpha | -0.00799332 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.00798008 |
| GOLGA3 | golgin A3 | -0.00797682 |
| INSIG1 | insulin induced gene 1 | -0.00777438 |
| AFMID | arylformamidase | -0.00774832 |
| MPHOSPH8 | M-phase phosphoprotein 8 | -0.00773563 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.00772298 |
| ITPKC | inositol-trisphosphate 3-kinase C | -0.0076673 |
| ZNF395 | zinc finger protein 395 | -0.00761869 |
| ZBTB7C | zinc finger and BTB domain containing 7C | -0.00758708 |
| LDLRAD4 | low density lipoprotein receptor class A domain containing 4 | -0.00758302 |
| KIF16B | kinesin family member 16B | -0.00754653 |
| CLYBL | citrate lyase beta like | -0.00753165 |
