| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Lonafarnib perturbation in HS-578T cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Lonafarnib_HS-578T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.162278 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.156 |
| MT2A | metallothionein 2A | 0.147025 |
| VEGFA | vascular endothelial growth factor A | 0.139149 |
| CD44 | CD44 molecule (Indian blood group) | 0.119863 |
| FN1 | fibronectin 1 | 0.0973155 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0740078 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0694096 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0666521 |
| ENO1 | enolase 1, (alpha) | 0.0569003 |
| AHNAK | AHNAK nucleoprotein | 0.0534394 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.053427 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0529092 |
| ASPH | aspartate beta-hydroxylase | 0.0437473 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0405866 |
| RPS8 | ribosomal protein S8 | 0.0396708 |
| NDRG1 | N-myc downstream regulated 1 | 0.0385308 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0369853 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0359972 |
| CALR | calreticulin | 0.035942 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.0343837 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0338796 |
| NAV1 | neuron navigator 1 | 0.0318331 |
| FAT1 | FAT atypical cadherin 1 | 0.0310339 |
| STC1 | stanniocalcin 1 | 0.0305988 |
| PLEC | plectin | 0.0304577 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0300771 |
| CDH13 | cadherin 13 | 0.0298112 |
| PRELID2 | PRELI domain containing 2 | 0.0293311 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0282194 |
| ATXN1 | ataxin 1 | 0.0258085 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0250106 |
| RUNX1 | runt-related transcription factor 1 | 0.0249449 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0243651 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0243183 |
| RPS19 | ribosomal protein S19 | 0.0239589 |
| EGFR | epidermal growth factor receptor | 0.0237774 |
| IL6 | interleukin 6 | 0.0237517 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0233375 |
| IGFBP7 | insulin-like growth factor binding protein 7 | 0.0232751 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0226228 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.022027 |
| DPYSL2 | dihydropyrimidinase-like 2 | 0.0216923 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0215668 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0215022 |
| HMGA2 | high mobility group AT-hook 2 | 0.0213588 |
| HDAC9 | histone deacetylase 9 | 0.0211711 |
| ADAM12 | ADAM metallopeptidase domain 12 | 0.0209114 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | 0.020854 |
| HLA-A | major histocompatibility complex, class I, A | 0.0208175 |
| S100A9 | S100 calcium binding protein A9 | 0.0207094 |
| FLNA | filamin A, alpha | 0.0206382 |
| GLIS3 | GLIS family zinc finger 3 | 0.0205639 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0199068 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | 0.0195837 |
| RACK1 | receptor for activated C kinase 1 | 0.0192947 |
| HLA-B | major histocompatibility complex, class I, B | 0.0190114 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0189549 |
| ECE1 | endothelin converting enzyme 1 | 0.0188833 |
| ACTG1 | actin gamma 1 | 0.0187924 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0187516 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0185788 |
| RPLP2 | ribosomal protein, large, P2 | 0.0185042 |
| RPL28 | ribosomal protein L28 | 0.0184496 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0181544 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0178956 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0178404 |
| NT5E | 5'-nucleotidase, ecto (CD73) | 0.0178009 |
| FER | fer (fps/fes related) tyrosine kinase | 0.0177245 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0175699 |
| RPS15 | ribosomal protein S15 | 0.0173737 |
| FBXL13 | F-box and leucine-rich repeat protein 13 | 0.0173399 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.017208 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0171698 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0167095 |
| RPL36 | ribosomal protein L36 | 0.0165414 |
| ANGPTL4 | angiopoietin-like 4 | 0.0162936 |
| NKAIN3 | Na+/K+ transporting ATPase interacting 3 | 0.0159817 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | 0.0158735 |
| RPN1 | ribophorin I | 0.0157977 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0156342 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | 0.0155636 |
| INHBA | inhibin, beta A | 0.0155551 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0154442 |
| EFNA5 | ephrin-A5 | 0.0153377 |
| BRD2 | bromodomain containing 2 | 0.0153183 |
| JAG1 | jagged 1 | 0.0152968 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0151594 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.0150304 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0146389 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0145504 |
| OSMR | oncostatin M receptor | 0.0145073 |
| RPL7 | ribosomal protein L7 | 0.014464 |
| SVIL | supervillin | 0.0144502 |
| SETBP1 | SET binding protein 1 | 0.0144217 |
| RPL5 | ribosomal protein L5 | 0.0143134 |
| VCL | vinculin | 0.0141873 |
| FAM107B | family with sequence similarity 107, member B | 0.0141061 |
| KIAA1217 | KIAA1217 | 0.0140231 |
| RPS3 | ribosomal protein S3 | 0.0138877 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0923467 |
| VIM | vimentin | -0.0833002 |
| COL1A2 | collagen, type I, alpha 2 | -0.0608595 |
| COL1A1 | collagen, type I, alpha 1 | -0.0603415 |
| CADM1 | cell adhesion molecule 1 | -0.0603222 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0577383 |
| IER3 | immediate early response 3 | -0.0497929 |
| TPM4 | tropomyosin 4 | -0.0438775 |
| ATP13A3 | ATPase type 13A3 | -0.0367642 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0305071 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0299162 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0295951 |
| LOX | lysyl oxidase | -0.0291456 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0284675 |
| PTMA | prothymosin, alpha | -0.0281012 |
| USP3 | ubiquitin specific peptidase 3 | -0.0279541 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0265979 |
| QKI | QKI, KH domain containing, RNA binding | -0.0250361 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0247324 |
| FBN1 | fibrillin 1 | -0.0236737 |
| GOLGA4 | golgin A4 | -0.0230513 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0228115 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0217318 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.0208761 |
| ZNF292 | zinc finger protein 292 | -0.0207459 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0202788 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0201935 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.02016 |
| GNAS | GNAS complex locus | -0.0198911 |
| SQLE | squalene epoxidase | -0.0196051 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0194524 |
| RLF | rearranged L-myc fusion | -0.0191344 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.019016 |
| ADM | adrenomedullin | -0.018529 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 | -0.0183513 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0178476 |
| PGK1 | phosphoglycerate kinase 1 | -0.017835 |
| SLC16A1 | solute carrier family 16 (monocarboxylate transporter), member 1 | -0.0177593 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0177367 |
| FBXO32 | F-box protein 32 | -0.0175428 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.01725 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0167864 |
| TRAM1 | translocation associated membrane protein 1 | -0.0166915 |
| TPM2 | tropomyosin 2 (beta) | -0.0159256 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0158099 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0155295 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | -0.0155259 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0155177 |
| CSDE1 | cold shock domain containing E1, RNA-binding | -0.0153706 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0150489 |
| JARID2 | jumonji, AT rich interactive domain 2 | -0.0149031 |
| MATR3 | matrin 3 | -0.0148797 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0148778 |
| CAVIN1 | caveolae associated protein 1 | -0.0147935 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | -0.0147469 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0146073 |
| PRRC1 | proline-rich coiled-coil 1 | -0.0144952 |
| HMGA1 | high mobility group AT-hook 1 | -0.0144854 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0144737 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0144428 |
| DSTN | destrin (actin depolymerizing factor) | -0.0144084 |
| VCAN | versican | -0.0143933 |
| RAB6A | RAB6A, member RAS oncogene family | -0.0140919 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | -0.0139731 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0137459 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0134981 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0133312 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0133031 |
| LOXL2 | lysyl oxidase-like 2 | -0.0132672 |
| KCTD9 | potassium channel tetramerization domain containing 9 | -0.0130473 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0130103 |
| BNC2 | basonuclin 2 | -0.0130065 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0129892 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | -0.0129161 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0127773 |
| THY1 | Thy-1 cell surface antigen | -0.0127765 |
| CD109 | CD109 molecule | -0.0126107 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0125141 |
| RBM39 | RNA binding motif protein 39 | -0.0124903 |
| S100A6 | S100 calcium binding protein A6 | -0.0122711 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.0122652 |
| OXR1 | oxidation resistance 1 | -0.0122619 |
| SPAG9 | sperm associated antigen 9 | -0.0121674 |
| PRR16 | proline rich 16 | -0.0120965 |
| TMEM165 | transmembrane protein 165 | -0.0120565 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | -0.0118693 |
| ABI1 | abl-interactor 1 | -0.0118646 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0118593 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0118531 |
| SEC63 | SEC63 homolog (S. cerevisiae) | -0.011721 |
| FAM162A | family with sequence similarity 162, member A | -0.0115731 |
| RNF145 | ring finger protein 145 | -0.011335 |
| LAMB3 | laminin, beta 3 | -0.0113148 |
| MYO1B | myosin IB | -0.0113092 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0112891 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0111057 |
| FGFR1 | fibroblast growth factor receptor 1 | -0.0110704 |
| HDLBP | high density lipoprotein binding protein | -0.0110628 |
| AFAP1 | actin filament associated protein 1 | -0.0110431 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0109862 |
