| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Lonafarnib perturbation in NCI-H1792 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Lonafarnib_NCI-H1792 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CD44 | CD44 molecule (Indian blood group) | 0.155314 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0706294 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0677398 |
| AHNAK | AHNAK nucleoprotein | 0.0638696 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0635946 |
| NAV2 | neuron navigator 2 | 0.0624274 |
| SMAD3 | SMAD family member 3 | 0.0600302 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0549346 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0548909 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0525577 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0512319 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0481953 |
| ANTXR2 | anthrax toxin receptor 2 | 0.0477193 |
| STC1 | stanniocalcin 1 | 0.0476918 |
| NDRG1 | N-myc downstream regulated 1 | 0.047351 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0446433 |
| RPS12 | ribosomal protein S12 | 0.044641 |
| RPS8 | ribosomal protein S8 | 0.044155 |
| VEGFA | vascular endothelial growth factor A | 0.0421083 |
| CDCP1 | CUB domain containing protein 1 | 0.0414392 |
| VIM | vimentin | 0.038962 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0386788 |
| RUNX1 | runt-related transcription factor 1 | 0.0384065 |
| LOX | lysyl oxidase | 0.0378998 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0376831 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0376087 |
| ENO1 | enolase 1, (alpha) | 0.0368455 |
| RPL37A | ribosomal protein L37a | 0.035901 |
| PRELID2 | PRELI domain containing 2 | 0.0358503 |
| EFNA5 | ephrin-A5 | 0.035748 |
| ANGPTL4 | angiopoietin-like 4 | 0.0348642 |
| RPS3 | ribosomal protein S3 | 0.0344867 |
| RPS6 | ribosomal protein S6 | 0.0334832 |
| OSMR | oncostatin M receptor | 0.0327956 |
| ANXA2 | annexin A2 | 0.0327645 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0319976 |
| HMGA2 | high mobility group AT-hook 2 | 0.0319882 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0314601 |
| LOXL2 | lysyl oxidase-like 2 | 0.0313694 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0312966 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | 0.0310826 |
| ECE1 | endothelin converting enzyme 1 | 0.0307671 |
| FBXL13 | F-box and leucine-rich repeat protein 13 | 0.0297417 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0294915 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0289498 |
| PKM | pyruvate kinase, muscle | 0.0287736 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | 0.0287594 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0281632 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.027979 |
| CA12 | carbonic anhydrase XII | 0.0278895 |
| ASPH | aspartate beta-hydroxylase | 0.0276157 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0275015 |
| SEPTIN9 | septin 9 | 0.0272439 |
| TGM2 | transglutaminase 2 | 0.0269659 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0268466 |
| RPL5 | ribosomal protein L5 | 0.026784 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0262304 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0258557 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0258374 |
| TMSB4X | thymosin beta 4, X-linked | 0.0257926 |
| RAI14 | retinoic acid induced 14 | 0.0256874 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0256652 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0254731 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0250999 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0245948 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0244611 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0242846 |
| MYO10 | myosin X | 0.0242731 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0239462 |
| MCL1 | myeloid cell leukemia 1 | 0.0234239 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.023215 |
| RPS13 | ribosomal protein S13 | 0.0231013 |
| RPLP2 | ribosomal protein, large, P2 | 0.0230842 |
| IRAK2 | interleukin-1 receptor-associated kinase 2 | 0.0229586 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.022822 |
| B2M | beta-2-microglobulin | 0.0223135 |
| RPL13A | ribosomal protein L13a | 0.0219944 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0219538 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0218997 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0214981 |
| RPL28 | ribosomal protein L28 | 0.0211993 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0208154 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0206955 |
| MSRB3 | methionine sulfoxide reductase B3 | 0.0205881 |
| RPLP0 | ribosomal protein, large, P0 | 0.020579 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0205122 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0204691 |
| GNGT1 | guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 | 0.0202311 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.020063 |
| FER | fer (fps/fes related) tyrosine kinase | 0.0197761 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0197494 |
| RPS29 | ribosomal protein S29 | 0.0197461 |
| RPL11 | ribosomal protein L11 | 0.0197457 |
| AMPD3 | adenosine monophosphate deaminase 3 | 0.0196576 |
| RPL37 | ribosomal protein L37 | 0.0195908 |
| EGFR | epidermal growth factor receptor | 0.0195212 |
| SLC41A2 | solute carrier family 41 (magnesium transporter), member 2 | 0.0193406 |
| RACK1 | receptor for activated C kinase 1 | 0.0193165 |
| MGST1 | microsomal glutathione S-transferase 1 | 0.0193024 |
| CAPN2 | calpain 2, (m/II) large subunit | 0.019162 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0765238 |
| TMSB10 | thymosin beta 10 | -0.0590167 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0404594 |
| RBM39 | RNA binding motif protein 39 | -0.0401113 |
| FTL | ferritin, light polypeptide | -0.0374279 |
| GOLGA4 | golgin A4 | -0.0351652 |
| PTMA | prothymosin, alpha | -0.0331518 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0314641 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0314118 |
| GLCCI1 | glucocorticoid induced 1 | -0.0275071 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0275026 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0262244 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.0259543 |
| HBP1 | HMG-box transcription factor 1 | -0.0228409 |
| MORF4L2 | mortality factor 4 like 2 | -0.0227738 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0189476 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0188567 |
| ARF4 | ADP-ribosylation factor 4 | -0.0188011 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.018672 |
| HDLBP | high density lipoprotein binding protein | -0.0186504 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0184323 |
| SPAG9 | sperm associated antigen 9 | -0.018258 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0182103 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0180471 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0178235 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0177868 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0177841 |
| SRP54 | signal recognition particle 54kDa | -0.0176637 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0176562 |
| GPC6 | glypican 6 | -0.0172788 |
| MECOM | MDS1 and EVI1 complex locus | -0.0167067 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.015891 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0157642 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0157413 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0151693 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.0148888 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0146884 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.0146001 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0145676 |
| COG5 | component of oligomeric golgi complex 5 | -0.0144783 |
| SYT1 | synaptotagmin I | -0.0144433 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 | -0.0143724 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.014302 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.0142621 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.014043 |
| GLG1 | golgi glycoprotein 1 | -0.0138194 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0137044 |
| USP3 | ubiquitin specific peptidase 3 | -0.0136741 |
| COPA | coatomer protein complex, subunit alpha | -0.0136737 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.0136529 |
| PARD3 | par-3 family cell polarity regulator | -0.0134217 |
| DDIT3 | DNA-damage-inducible transcript 3 | -0.0130515 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | -0.012906 |
| TMEM263 | transmembrane protein 263 | -0.0125437 |
| LRRFIP2 | leucine rich repeat (in FLII) interacting protein 2 | -0.0122915 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.012247 |
| RAB5A | RAB5A, member RAS oncogene family | -0.0121644 |
| AUH | AU RNA binding protein/enoyl-CoA hydratase | -0.0121495 |
| IFI44 | interferon-induced protein 44 | -0.012005 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0119921 |
| SUCO | SUN domain containing ossification factor | -0.0118574 |
| ATXN2 | ataxin 2 | -0.0118501 |
| ZNF609 | zinc finger protein 609 | -0.0115747 |
| GNAS | GNAS complex locus | -0.0115698 |
| TMTC1 | transmembrane and tetratricopeptide repeat containing 1 | -0.0114781 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0114677 |
| TAOK1 | TAO kinase 1 | -0.0113471 |
| RIGI | RNA sensor RIG-I | -0.0113383 |
| EIF2AK3 | eukaryotic translation initiation factor 2-alpha kinase 3 | -0.0112131 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.0111923 |
| KLHL24 | kelch-like family member 24 | -0.010973 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0109301 |
| VMP1 | vacuole membrane protein 1 | -0.0109292 |
| WASF2 | WAS protein family, member 2 | -0.0109208 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0107352 |
| UBE2B | ubiquitin-conjugating enzyme E2B | -0.0106547 |
| HIBADH | 3-hydroxyisobutyrate dehydrogenase | -0.0105805 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.0105657 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0104718 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | -0.010378 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0102669 |
| CFAP73 | cilia and flagella associated protein 73 | -0.0102374 |
| POU2F1 | POU class 2 homeobox 1 | -0.0102082 |
| TNS3 | tensin 3 | -0.0101635 |
| MEF2A | myocyte enhancer factor 2A | -0.00999796 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.00994576 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.00982454 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.00981674 |
| TJP1 | tight junction protein 1 | -0.00968617 |
| PHF21A | PHD finger protein 21A | -0.00967811 |
| CFDP1 | craniofacial development protein 1 | -0.00965457 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.00963319 |
| EGR1 | early growth response 1 | -0.00962151 |
| CCDC88A | coiled-coil domain containing 88A | -0.00956726 |
| RB1CC1 | RB1-inducible coiled-coil 1 | -0.00954909 |
| RAB6A | RAB6A, member RAS oncogene family | -0.00954016 |
| DNER | delta/notch-like EGF repeat containing | -0.00943996 |
| CLINT1 | clathrin interactor 1 | -0.00941672 |
| PHIP | pleckstrin homology domain interacting protein | -0.00939659 |
| IFI44L | interferon-induced protein 44-like | -0.00937245 |
