| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Lonafarnib perturbation in SNU-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Lonafarnib_SNU-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AHNAK | AHNAK nucleoprotein | 0.12202 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.103453 |
| FOXP1 | forkhead box P1 | 0.0615601 |
| VCL | vinculin | 0.0602318 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.0520159 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.050495 |
| TMSB4X | thymosin beta 4, X-linked | 0.0502434 |
| HDAC9 | histone deacetylase 9 | 0.0499912 |
| SOX6 | SRY (sex determining region Y)-box 6 | 0.048385 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0478672 |
| PRELID2 | PRELI domain containing 2 | 0.0403363 |
| EGFR | epidermal growth factor receptor | 0.039898 |
| MYO5C | myosin VC | 0.0373658 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0369403 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0365911 |
| GSE1 | Gse1 coiled-coil protein | 0.0353103 |
| MACROD2 | MACRO domain containing 2 | 0.0341734 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | 0.0330426 |
| EZR | ezrin | 0.0328977 |
| GLI3 | GLI family zinc finger 3 | 0.0306934 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0301254 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0290244 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0288226 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0282219 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0277968 |
| PTMA | prothymosin, alpha | 0.0275996 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | 0.027587 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | 0.0271251 |
| BMP2K | BMP2 inducible kinase | 0.0268656 |
| PKM | pyruvate kinase, muscle | 0.0265304 |
| MKI67 | marker of proliferation Ki-67 | 0.0261185 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0255868 |
| ENO1 | enolase 1, (alpha) | 0.0250182 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0239942 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.023473 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0232299 |
| FER1L6 | fer-1-like family member 6 | 0.0230714 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.0228557 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0225835 |
| RHOA | ras homolog family member A | 0.0223887 |
| EML4 | echinoderm microtubule associated protein like 4 | 0.0222607 |
| PDGFC | platelet derived growth factor C | 0.0222514 |
| MLIP | muscular LMNA-interacting protein | 0.0213499 |
| ALDH1A2 | aldehyde dehydrogenase 1 family, member A2 | 0.0213246 |
| NAV2 | neuron navigator 2 | 0.0209771 |
| GLI2 | GLI family zinc finger 2 | 0.0205308 |
| SEPTIN9 | septin 9 | 0.0204084 |
| RFC3 | replication factor C (activator 1) 3, 38kDa | 0.0199047 |
| ZNF608 | zinc finger protein 608 | 0.0195483 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0194767 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | 0.0194272 |
| DUSP4 | dual specificity phosphatase 4 | 0.0187982 |
| DIAPH3 | diaphanous-related formin 3 | 0.0187838 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0185814 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0184165 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0183575 |
| TJP1 | tight junction protein 1 | 0.0182858 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.018083 |
| BMP10 | bone morphogenetic protein 10 | 0.0180274 |
| NBEA | neurobeachin | 0.0179378 |
| AHCYL2 | adenosylhomocysteinase-like 2 | 0.0175854 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0175441 |
| RRM2 | ribonucleotide reductase M2 | 0.0175299 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0172146 |
| FAT1 | FAT atypical cadherin 1 | 0.0171648 |
| ANLN | anillin, actin binding protein | 0.0169297 |
| AMOTL2 | angiomotin like 2 | 0.0168741 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | 0.0168434 |
| ARL4C | ADP-ribosylation factor-like 4C | 0.0166837 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0166673 |
| IFI16 | interferon, gamma-inducible protein 16 | 0.0163315 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.0162211 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.0160374 |
| SMYD3 | SET and MYND domain containing 3 | 0.0158559 |
| FER | fer (fps/fes related) tyrosine kinase | 0.0157602 |
| LRRC7 | leucine rich repeat containing 7 | 0.0155506 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0154407 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.01543 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0153845 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0153513 |
| EXOC4 | exocyst complex component 4 | 0.0153493 |
| CUX1 | cut-like homeobox 1 | 0.0153219 |
| ANXA1 | annexin A1 | 0.0151634 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0148405 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | 0.0147401 |
| RFX3 | regulatory factor X, 3 (influences HLA class II expression) | 0.014732 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0146369 |
| CREB5 | cAMP responsive element binding protein 5 | 0.0143219 |
| SQSTM1 | sequestosome 1 | 0.0142884 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0138635 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.013861 |
| TGFBR3 | transforming growth factor, beta receptor III | 0.0136146 |
| DOCK1 | dedicator of cytokinesis 1 | 0.0135814 |
| DPYD | dihydropyrimidine dehydrogenase | 0.0134716 |
| TBC1D5 | TBC1 domain family, member 5 | 0.013431 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0134251 |
| INTS6 | integrator complex subunit 6 | 0.0133931 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.0132668 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0131106 |
| LMCD1 | LIM and cysteine-rich domains 1 | 0.0130464 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0486474 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.032717 |
| RBM39 | RNA binding motif protein 39 | -0.0253341 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0235876 |
| TXNRD1 | thioredoxin reductase 1 | -0.0231501 |
| GOLGA4 | golgin A4 | -0.0219403 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0210328 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0177777 |
| RTN4 | reticulon 4 | -0.0172381 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0169744 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0169247 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -0.0143496 |
| LDHA | lactate dehydrogenase A | -0.0139625 |
| SLC1A3 | solute carrier family 1 (glial high affinity glutamate transporter), member 3 | -0.0137014 |
| S100A6 | S100 calcium binding protein A6 | -0.0129391 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0126649 |
| SESN2 | sestrin 2 | -0.0120276 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0120142 |
| NEBL | nebulette | -0.0116613 |
| ANK2 | ankyrin 2, neuronal | -0.0114735 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0111608 |
| TFG | TRK-fused gene | -0.0110688 |
| CHD1 | chromodomain helicase DNA binding protein 1 | -0.0110308 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0110254 |
| COG5 | component of oligomeric golgi complex 5 | -0.0109314 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0107955 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0106668 |
| SRSF11 | serine/arginine-rich splicing factor 11 | -0.0106552 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.0106323 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0105459 |
| HMGA1 | high mobility group AT-hook 1 | -0.0103729 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0102649 |
| TMEM41B | transmembrane protein 41B | -0.0102226 |
| WDR43 | WD repeat domain 43 | -0.00988453 |
| CCNL1 | cyclin L1 | -0.00985309 |
| SETD5 | SET domain containing 5 | -0.00955569 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.00944553 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.00941003 |
| ZMAT3 | zinc finger, matrin-type 3 | -0.00938586 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.00929397 |
| RPS19 | ribosomal protein S19 | -0.00899699 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.00871452 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | -0.00869692 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.00862351 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.00854123 |
| IBTK | inhibitor of Bruton agammaglobulinemia tyrosine kinase | -0.00829908 |
| RPL35A | ribosomal protein L35a | -0.0081731 |
| TMEM39A | transmembrane protein 39A | -0.00811161 |
| NOP58 | NOP58 ribonucleoprotein | -0.00800478 |
| COPA | coatomer protein complex, subunit alpha | -0.00780623 |
| XPO1 | exportin 1 | -0.007794 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.00779083 |
| NUP58 | nucleoporin 58 | -0.0076774 |
| RPL27A | ribosomal protein L27a | -0.00755303 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | -0.00751714 |
| EPB41 | erythrocyte membrane protein band 4.1 | -0.00749178 |
| RB1CC1 | RB1-inducible coiled-coil 1 | -0.00740805 |
| RPL13A | ribosomal protein L13a | -0.00737993 |
| RPS24 | ribosomal protein S24 | -0.00732472 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | -0.00732301 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.00730996 |
| PRRC1 | proline-rich coiled-coil 1 | -0.00724991 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.00718519 |
| PTEN | phosphatase and tensin homolog | -0.00717804 |
| MSI2 | musashi RNA-binding protein 2 | -0.00714136 |
| PSAT1 | phosphoserine aminotransferase 1 | -0.00708392 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.00707165 |
| VIM | vimentin | -0.00700074 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.00697212 |
| CEP95 | centrosomal protein 95kDa | -0.0069218 |
| PREPL | prolyl endopeptidase-like | -0.00678776 |
| RPS16 | ribosomal protein S16 | -0.00678149 |
| TBC1D23 | TBC1 domain family, member 23 | -0.00677495 |
| TIGAR | TP53 induced glycolysis regulatory phosphatase | -0.00661377 |
| SMC3 | structural maintenance of chromosomes 3 | -0.006581 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.00655994 |
| MT2A | metallothionein 2A | -0.00649505 |
| GOLT1B | golgi transport 1B | -0.00648624 |
| RNMT | RNA (guanine-7-) methyltransferase | -0.00646352 |
| GNL3 | guanine nucleotide binding protein-like 3 (nucleolar) | -0.00641414 |
| FTL | ferritin, light polypeptide | -0.00640093 |
| MSMO1 | methylsterol monooxygenase 1 | -0.00636886 |
| INSIG1 | insulin induced gene 1 | -0.00630951 |
| CLIC4 | chloride intracellular channel 4 | -0.00627462 |
| NCOR1 | nuclear receptor corepressor 1 | -0.00614296 |
| NUP54 | nucleoporin 54kDa | -0.00610932 |
| CD46 | CD46 molecule, complement regulatory protein | -0.00610216 |
| RPLP2 | ribosomal protein, large, P2 | -0.00602783 |
| LMAN1 | lectin, mannose-binding, 1 | -0.00600013 |
| LUC7L2 | LUC7-like 2 (S. cerevisiae) | -0.00599102 |
| PPP4R3A | protein phosphatase 4 regulatory subunit 3A | -0.00598652 |
| USP3 | ubiquitin specific peptidase 3 | -0.00594398 |
| RNF149 | ring finger protein 149 | -0.0059379 |
| VPS13A | vacuolar protein sorting 13 homolog A (S. cerevisiae) | -0.00592149 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.00591048 |
| ZBTB10 | zinc finger and BTB domain containing 10 | -0.0059044 |
| TNPO1 | transportin 1 | -0.00587463 |
| ZFAND6 | zinc finger, AN1-type domain 6 | -0.00587056 |
| FDPS | farnesyl diphosphate synthase | -0.00583916 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | -0.00579856 |
