| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Lonafarnib perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Lonafarnib_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.137767 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.120645 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0981491 |
| NDRG1 | N-myc downstream regulated 1 | 0.0956352 |
| VEGFA | vascular endothelial growth factor A | 0.0811992 |
| HDAC9 | histone deacetylase 9 | 0.0585273 |
| CD44 | CD44 molecule (Indian blood group) | 0.0575554 |
| NAV2 | neuron navigator 2 | 0.0491085 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0459878 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0446748 |
| HLA-B | major histocompatibility complex, class I, B | 0.0441376 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0440348 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.0440219 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0437828 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0434253 |
| RND3 | Rho family GTPase 3 | 0.0412803 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0391948 |
| FNIP1 | folliculin interacting protein 1 | 0.0391584 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0387773 |
| PRELID2 | PRELI domain containing 2 | 0.0385763 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0371372 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0326262 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.0325273 |
| STC1 | stanniocalcin 1 | 0.0318302 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0317435 |
| SYNJ2 | synaptojanin 2 | 0.0315327 |
| SQSTM1 | sequestosome 1 | 0.0307814 |
| HELZ | helicase with zinc finger | 0.0296551 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0277975 |
| SPAG9 | sperm associated antigen 9 | 0.0275899 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0272442 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0268784 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0266773 |
| PDE10A | phosphodiesterase 10A | 0.0265102 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0262633 |
| HLA-C | major histocompatibility complex, class I, C | 0.0261146 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0258716 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0256156 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.02518 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0245588 |
| TRAM2 | translocation associated membrane protein 2 | 0.0243316 |
| LOXL2 | lysyl oxidase-like 2 | 0.0242915 |
| ARFGEF3 | ARFGEF family member 3 | 0.0238774 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0236452 |
| JMJD1C | jumonji domain containing 1C | 0.02323 |
| RUNX1 | runt-related transcription factor 1 | 0.0229152 |
| SFTPA2 | surfactant protein A2 | 0.0228534 |
| MYOF | myoferlin | 0.0226573 |
| ZNF292 | zinc finger protein 292 | 0.0225662 |
| ASPH | aspartate beta-hydroxylase | 0.0221899 |
| SEPTIN9 | septin 9 | 0.0217975 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0217829 |
| ICAM1 | intercellular adhesion molecule 1 | 0.021709 |
| DUSP10 | dual specificity phosphatase 10 | 0.0215297 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.020835 |
| ANXA2 | annexin A2 | 0.0207704 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.020599 |
| HLA-A | major histocompatibility complex, class I, A | 0.0205911 |
| ARRDC3 | arrestin domain containing 3 | 0.0203987 |
| FHIT | fragile histidine triad | 0.0200458 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0199541 |
| FMNL2 | formin-like 2 | 0.0197341 |
| ADM | adrenomedullin | 0.0196644 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | 0.0193295 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | 0.0192466 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0189464 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0189048 |
| ARL4C | ADP-ribosylation factor-like 4C | 0.0187399 |
| NT5E | 5'-nucleotidase, ecto (CD73) | 0.0187177 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0184195 |
| FOXO3 | forkhead box O3 | 0.0183414 |
| AHNAK | AHNAK nucleoprotein | 0.0180405 |
| COL5A1 | collagen, type V, alpha 1 | 0.0179506 |
| VAC14 | Vac14 homolog (S. cerevisiae) | 0.0178844 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0177711 |
| WWOX | WW domain containing oxidoreductase | 0.0176549 |
| CTSB | cathepsin B | 0.0173868 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0173396 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0172382 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0171746 |
| OGA | O-GlcNAcase | 0.0170398 |
| RHOBTB3 | Rho-related BTB domain containing 3 | 0.0170364 |
| WDFY1 | WD repeat and FYVE domain containing 1 | 0.0168125 |
| NOTCH2 | notch 2 | 0.01666 |
| GOLGA4 | golgin A4 | 0.0166548 |
| CRYBG3 | beta-gamma crystallin domain containing 3 | 0.0157369 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0156198 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0156117 |
| ANKRD1 | ankyrin repeat domain 1 (cardiac muscle) | 0.0154579 |
| CDCP1 | CUB domain containing protein 1 | 0.015369 |
| SMAD3 | SMAD family member 3 | 0.0152916 |
| KLF6 | Kruppel-like factor 6 | 0.0151672 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0149415 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0149119 |
| IRS2 | insulin receptor substrate 2 | 0.0148514 |
| PGM3 | phosphoglucomutase 3 | 0.0147967 |
| RPS2 | ribosomal protein S2 | 0.0147076 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0144715 |
| B2M | beta-2-microglobulin | 0.01425 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0142392 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FRMD4A | FERM domain containing 4A | -0.130779 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0664251 |
| GLIS3 | GLIS family zinc finger 3 | -0.064963 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.053329 |
| THBS1 | thrombospondin 1 | -0.0532257 |
| DST | dystonin | -0.0528084 |
| BICC1 | BicC family RNA binding protein 1 | -0.0502279 |
| VIM | vimentin | -0.0474715 |
| TPM4 | tropomyosin 4 | -0.0445571 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0439605 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0438605 |
| VCL | vinculin | -0.0411777 |
| RAI14 | retinoic acid induced 14 | -0.040861 |
| POTEF | POTE ankyrin domain family, member F | -0.0398524 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0391799 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0385435 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0385186 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.0360639 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0349462 |
| TMSB10 | thymosin beta 10 | -0.0325735 |
| CADM1 | cell adhesion molecule 1 | -0.0305754 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0303986 |
| PTMA | prothymosin, alpha | -0.0293301 |
| RPS27A | ribosomal protein S27a | -0.0278798 |
| DIAPH2 | diaphanous-related formin 2 | -0.027438 |
| TPM1 | tropomyosin 1 (alpha) | -0.0266586 |
| COL1A1 | collagen, type I, alpha 1 | -0.0264296 |
| TENM2 | teneurin transmembrane protein 2 | -0.0261264 |
| LRRC7 | leucine rich repeat containing 7 | -0.0257587 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0255983 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0255979 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0253824 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0246956 |
| TXNRD1 | thioredoxin reductase 1 | -0.0245215 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0245103 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | -0.0236593 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0226143 |
| FN1 | fibronectin 1 | -0.0218942 |
| IL6 | interleukin 6 | -0.0218479 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0218073 |
| PALLD | palladin, cytoskeletal associated protein | -0.0214801 |
| PDE1C | phosphodiesterase 1C, calmodulin-dependent 70kDa | -0.0212444 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0209961 |
| DCBLD1 | discoidin, CUB and LCCL domain containing 1 | -0.0204572 |
| SRGN | serglycin | -0.020444 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0204212 |
| COL1A2 | collagen, type I, alpha 2 | -0.0200295 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | -0.019925 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.019678 |
| CLIC4 | chloride intracellular channel 4 | -0.0192417 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0188995 |
| RPS3 | ribosomal protein S3 | -0.0186989 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0186626 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0186174 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0178627 |
| QKI | QKI, KH domain containing, RNA binding | -0.0178268 |
| CASK | calcium/calmodulin-dependent serine protein kinase (MAGUK family) | -0.0178183 |
| RIGI | RNA sensor RIG-I | -0.0177914 |
| ARFGAP3 | ADP-ribosylation factor GTPase activating protein 3 | -0.0176837 |
| CALD1 | caldesmon 1 | -0.017204 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0171289 |
| CSDE1 | cold shock domain containing E1, RNA-binding | -0.0170673 |
| TMEM123 | transmembrane protein 123 | -0.0168073 |
| NCKAP5 | NCK-associated protein 5 | -0.0166938 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0165818 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0164913 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0164389 |
| ACTG1 | actin gamma 1 | -0.0161915 |
| CLMP | CXADR-like membrane protein | -0.0158885 |
| TNIP1 | TNFAIP3 interacting protein 1 | -0.0157695 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.0155335 |
| THOC2 | THO complex 2 | -0.0155268 |
| DSTN | destrin (actin depolymerizing factor) | -0.0155226 |
| RASAL2 | RAS protein activator like 2 | -0.0154522 |
| CNTN6 | contactin 6 | -0.0154017 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0153547 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0152484 |
| TCF12 | transcription factor 12 | -0.0150918 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0150579 |
| COL8A1 | collagen, type VIII, alpha 1 | -0.0150349 |
| GREM1 | gremlin 1, DAN family BMP antagonist | -0.0149278 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0149148 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0148783 |
| FOXP1 | forkhead box P1 | -0.0148139 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0147739 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0147677 |
| TAOK3 | TAO kinase 3 | -0.0147494 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0144963 |
| RUNX2 | runt-related transcription factor 2 | -0.0144036 |
| BNC2 | basonuclin 2 | -0.0142598 |
| PCBP2 | poly(rC) binding protein 2 | -0.0142412 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0142403 |
| TNS3 | tensin 3 | -0.0142162 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | -0.0141737 |
| UBC | ubiquitin C | -0.0141048 |
| TGFB2 | transforming growth factor, beta 2 | -0.0137679 |
| VCAN | versican | -0.0137358 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.0136569 |
| EHBP1 | EH domain binding protein 1 | -0.0135223 |
| PRR16 | proline rich 16 | -0.0135183 |
